FTHL17 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FTHL17
Entrez Gene ID	53940
Full Name	ferritin heavy chain like 17
Synonyms	CT38
General protein information	Preferred Names ferritin heavy chain like 17 Names ferritin heavy polypeptide-like 17 cancer/testis antigen 38 ferritin, heavy polypeptide-like 17
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp21.2
Summary	This gene encodes a ferritin heavy chain-like protein. This gene is primarily expressed in embryonic germ cells. The encoded protein may lack ferroxidase activity. Multiple pseudogenes of this gene are found on chromosome X. [provided by RefSeq, Oct 2016].
Disorder MIM:	300308

mRNA and Protein(s)

mRNA	Protein	Name
NM_031894.2	NP_114100.1	ferritin heavy polypeptide-like 17
NM_031894.3	NP_114100.1	ferritin heavy polypeptide-like 17

Pathways from BioSystems

Homologies

Homo sapiens (human)	FTHL17	NP_114100.1
	FTHL17	XP_001096278.2
Pan troglodytes (chimpanzee)	FTHL17	XP_528923.2

Gene Ontology
Bibliography

Related articles in PubMed

The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization.
Ruzzenenti P, Asperti M, Mitola S, Crescini E, Maccarinelli F, Gryzik M, Regoni M, Finazzi D, Arosio P, Poli M
Biochimica et biophysica acta1850(6)1267-73(2015 Jun)

Severe XIST hypomethylation clearly distinguishes (SRY+) 46,XX-maleness from Klinefelter syndrome.
Poplinski A, Wieacker P, Kliesch S, Gromoll J
European journal of endocrinology162(1)169-75(2010 Jan)

Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma.
Atanackovic D, Blum I, Cao Y, Wenzel S, Bartels K, Faltz C, Hossfeld DK, Hegewisch-Becker S, Bokemeyer C, Leuwer R
Cancer biology & therapy5(9)1218-25(2006 Sep)

Molecular and cytogenetic characterization of two azoospermic patients with X-autosome translocation.
Lee S, Lee SH, Chung TG, Kim HJ, Yoon TK, Kwak IP, Park SH, Cha WT, Cho SW, Cha KY
Journal of assisted reproduction and genetics20(9)385-9(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FTHL17 encodes a ferritin-like protein without ferroxidase activity. Its restricted embryonic expression and partial nuclear localization suggest that this novel ferritin type may have functions other than iron storage.
Title: The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization.

The following FTHL17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FTHL17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17859	NM_031894.3 Latest version!	Homo sapiens ferritin heavy chain like 17 (FTHL17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu17859	NM_031894.2	Homo sapiens ferritin heavy chain like 17 (FTHL17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FTHL17 ( NM_031894.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_114100.1 Homo sapiens ferritin heavy chain like 17 (FTHL17), mRNA.

Price & Availability↑

CloneID	OHu17859
Clone ID Related Accession (Same CDS sequence)	NM_031894.2 , NM_031894.3
Accession Version	NM_031894.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	ferritin heavy polypeptide-like 17
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF285592.1. This sequence is a reference standard in the RefSeqGene project. On Oct 22, 2009 this sequence version replaced NM_031894.1. ##Evidence-Data-START## Transcript is intronless :: AF285592.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCACCG CCCAGCCGTC GCAGGTGCGC CAGAAGTACG ACACCAACTG CGACGCCGCC 
ATCAACAGCC ACATCACGCT GGAGCTCTAC ACCTCCTACC TGTACCTGTC TATGGCCTTC 
TACTTCAACC GGGACGACGT GGCCCTGGAG AACTTCTTCC GCTACTTCCT GCGCCTGTCG 
GACGACAAAA TGGAGCATGC CCAGAAGCTG ATGAGGCTGC AGAACCTGCG CGGTGGCCAC 
ATCTGCCTTC ACGATATCAG GAAGCCAGAG TGCCAAGGCT GGGAGAGCGG GCTCGTGGCC 
ATGGAGTCCG CCTTCCACCT GGAGAAGAAC GTCAACCAGA GCCTGCTGGA TCTGTACCAG 
CTGGCCGTGG AGAAGGGCGA CCCCCAGCTG TGCCACTTCC TGGAGAGCCA CTACCTGCAC 
GAGCAAGTCA AGACCATCAA AGAGCTGGGT GGCTACGTGA GCAACCTGCG CAAGATTTGT 
TCCCCGGAAG CCGGCCTGGC TGAGTACCTG TTCGACAAGC TCACCCTGGG CGGCCGCGTC 
AAAGAGACTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114100.1
CDS	101..652
Translation	MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLSDDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQLAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRVKET

Target ORF information:

RefSeq Version	NM_031894.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ferritin heavy chain like 17 (FTHL17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031894.2

ORF Insert Sequence:

ATGGCCACCG CCCAGCCGTC GCAGGTGCGC CAGAAGTACG ACACCAACTG CGACGCCGCC 
ATCAACAGCC ACATCACGCT GGAGCTCTAC ACCTCCTACC TGTACCTGTC TATGGCCTTC 
TACTTCAACC GGGACGACGT GGCCCTGGAG AACTTCTTCC GCTACTTCCT GCGCCTGTCG 
GACGACAAAA TGGAGCATGC CCAGAAGCTG ATGAGGCTGC AGAACCTGCG CGGTGGCCAC 
ATCTGCCTTC ACGATATCAG GAAGCCAGAG TGCCAAGGCT GGGAGAGCGG GCTCGTGGCC 
ATGGAGTCCG CCTTCCACCT GGAGAAGAAC GTCAACCAGA GCCTGCTGGA TCTGTACCAG 
CTGGCCGTGG AGAAGGGCGA CCCCCAGCTG TGCCACTTCC TGGAGAGCCA CTACCTGCAC 
GAGCAAGTCA AGACCATCAA AGAGCTGGGT GGCTACGTGA GCAACCTGCG CAAGATTTGT 
TCCCCGGAAG CCGGCCTGGC TGAGTACCTG TTCGACAAGC TCACCCTGGG CGGCCGCGTC 
AAAGAGACTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FTHL17 ( NM_031894.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_114100.1 Homo sapiens ferritin heavy chain like 17 (FTHL17), mRNA.

Price & Availability↑

CloneID	OHu17859
Clone ID Related Accession (Same CDS sequence)	NM_031894.2 , NM_031894.3
Accession Version	NM_031894.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	ferritin heavy polypeptide-like 17
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF285592.1 and AC006061.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_031894.2. ##Evidence-Data-START## Transcript is intronless :: BC100770.1, GQ891506.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000359202.5/ ENSP00000368207.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCACCG CCCAGCCGTC GCAGGTGCGC CAGAAGTACG ACACCAACTG CGACGCCGCC 
ATCAACAGCC ACATCACGCT GGAGCTCTAC ACCTCCTACC TGTACCTGTC TATGGCCTTC 
TACTTCAACC GGGACGACGT GGCCCTGGAG AACTTCTTCC GCTACTTCCT GCGCCTGTCG 
GACGACAAAA TGGAGCATGC CCAGAAGCTG ATGAGGCTGC AGAACCTGCG CGGTGGCCAC 
ATCTGCCTTC ACGATATCAG GAAGCCAGAG TGCCAAGGCT GGGAGAGCGG GCTCGTGGCC 
ATGGAGTCCG CCTTCCACCT GGAGAAGAAC GTCAACCAGA GCCTGCTGGA TCTGTACCAG 
CTGGCCGTGG AGAAGGGCGA CCCCCAGCTG TGCCACTTCC TGGAGAGCCA CTACCTGCAC 
GAGCAAGTCA AGACCATCAA AGAGCTGGGT GGCTACGTGA GCAACCTGCG CAAGATTTGT 
TCCCCGGAAG CCGGCCTGGC TGAGTACCTG TTCGACAAGC TCACCCTGGG CGGCCGCGTC 
AAAGAGACTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114100.1
CDS	89..640
Translation	MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLSDDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQLAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRVKET

Target ORF information:

RefSeq Version	NM_031894.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ferritin heavy chain like 17 (FTHL17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031894.3

ORF Insert Sequence:

ATGGCCACCG CCCAGCCGTC GCAGGTGCGC CAGAAGTACG ACACCAACTG CGACGCCGCC 
ATCAACAGCC ACATCACGCT GGAGCTCTAC ACCTCCTACC TGTACCTGTC TATGGCCTTC 
TACTTCAACC GGGACGACGT GGCCCTGGAG AACTTCTTCC GCTACTTCCT GCGCCTGTCG 
GACGACAAAA TGGAGCATGC CCAGAAGCTG ATGAGGCTGC AGAACCTGCG CGGTGGCCAC 
ATCTGCCTTC ACGATATCAG GAAGCCAGAG TGCCAAGGCT GGGAGAGCGG GCTCGTGGCC 
ATGGAGTCCG CCTTCCACCT GGAGAAGAAC GTCAACCAGA GCCTGCTGGA TCTGTACCAG 
CTGGCCGTGG AGAAGGGCGA CCCCCAGCTG TGCCACTTCC TGGAGAGCCA CTACCTGCAC 
GAGCAAGTCA AGACCATCAA AGAGCTGGGT GGCTACGTGA GCAACCTGCG CAAGATTTGT 
TCCCCGGAAG CCGGCCTGGC TGAGTACCTG TTCGACAAGC TCACCCTGGG CGGCCGCGTC 
AAAGAGACTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization.
Biochimica et biophysica acta1850(6)1267-73(2015 Jun)
Ruzzenenti P,Asperti M,Mitola S,Crescini E,Maccarinelli F,Gryzik M,Regoni M,Finazzi D,Arosio P,Poli M

Severe XIST hypomethylation clearly distinguishes (SRY+) 46,XX-maleness from Klinefelter syndrome.
European journal of endocrinology162(1)169-75(2010 Jan)
Poplinski A,Wieacker P,Kliesch S,Gromoll J

Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma.
Cancer biology & therapy5(9)1218-25(2006 Sep)
Atanackovic D,Blum I,Cao Y,Wenzel S,Bartels K,Faltz C,Hossfeld DK,Hegewisch-Becker S,Bokemeyer C,Leuwer R

Molecular and cytogenetic characterization of two azoospermic patients with X-autosome translocation.
Journal of assisted reproduction and genetics20(9)385-9(2003 Sep)
Lee S,Lee SH,Chung TG,Kim HJ,Yoon TK,Kwak IP,Park SH,Cha WT,Cho SW,Cha KY

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FTHL17 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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