PLG cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLG
Entrez Gene ID	5340
Full Name	plasminogen
General protein information	Preferred Names plasminogen Names plasminogen plasmin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q26
Summary	The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009].
Disorder MIM:	173350
Disorder Html:	Dysplasminogenemia, 217090 (3); Plasminogen deficiency, type I, 217090 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000301.4	NP_000292.1	plasminogen isoform 1 precursor
NM_001168338.1	NP_001161810.1	plasminogen isoform 2 precursor
NM_000301.3	NP_000292.1	plasminogen isoform 1 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PLG	NP_776376.1
Mus musculus (house mouse)	Plg	NP_032903.3
Danio rerio (zebrafish)	plg	NP_958880.1
Pan troglodytes (chimpanzee)	PLG	XP_001152889.1
	PLG	NP_001036540.1
Canis lupus familiaris (dog)	PLG	XP_005615617.1
Rattus norvegicus (Norway rat)	Plg	NP_445943.1
Caenorhabditis elegans (roundworm)	try-1	NP_494910.2
Xenopus tropicalis (tropical clawed frog)	LOC100496227	XP_002938616.2
Homo sapiens (human)	PLG	NP_000292.1
Gallus gallus (chicken)	PLG	XP_419618.2

Gene Ontology

The following PLG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22248	NM_001168338.1 Latest version!	Homo sapiens plasminogen (PLG), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu22912	NM_000301.4 Latest version!	Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu22912	NM_000301.3	Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLG ( NM_001168338.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001161810.1 Homo sapiens plasminogen (PLG), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22248
Clone ID Related Accession (Same CDS sequence)	NM_001168338.1
Accession Version	NM_001168338.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	plasminogen isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR004070.1 and AL109933.25. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CB116968.1, DA639760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC 
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT 
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001161810.1
CDS	113..523
Translation	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPR

Target ORF information:

RefSeq Version	NM_001168338.1
Organism	Homo sapiens(human)
Definition	Homo sapiens plasminogen (PLG), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001168338.1

ORF Insert Sequence:

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC 
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT 
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLG ( NM_000301.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000292.1 Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22912
Clone ID Related Accession (Same CDS sequence)	NM_000301.4 , NM_000301.3
Accession Version	NM_000301.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-22
Organism	Homo sapiens(human)
Product	plasminogen isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR004070.1, M74220.1, X05199.1 and AL109933.25. This sequence is a reference standard in the RefSeqGene project. On Dec 3, 2009 this sequence version replaced NM_000301.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X05199.1, BC060513.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC 
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT 
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGATT CTCACCTGCT 
ACACACCCCT CAGAGGGACT GGAGGAGAAC TACTGCAGGA ATCCAGACAA CGATCCGCAG 
GGGCCCTGGT GCTATACTAC TGATCCAGAA AAGAGATATG ACTACTGCGA CATTCTTGAG 
TGTGAAGAGG AATGTATGCA TTGCAGTGGA GAAAACTATG ACGGCAAAAT TTCCAAGACC 
ATGTCTGGAC TGGAATGCCA GGCCTGGGAC TCTCAGAGCC CACACGCTCA TGGATACATT 
CCTTCCAAAT TTCCAAACAA GAACCTGAAG AAGAATTACT GTCGTAACCC CGATAGGGAG 
CTGCGGCCTT GGTGTTTCAC CACCGACCCC AACAAGCGCT GGGAACTTTG TGACATCCCC 
CGCTGCACAA CACCTCCACC ATCTTCTGGT CCCACCTACC AGTGTCTGAA GGGAACAGGT 
GAAAACTATC GCGGGAATGT GGCTGTTACC GTGTCCGGGC ACACCTGTCA GCACTGGAGT 
GCACAGACCC CTCACACACA TAACAGGACA CCAGAAAACT TCCCCTGCAA AAATTTGGAT 
GAAAACTACT GCCGCAATCC TGACGGAAAA AGGGCCCCAT GGTGCCATAC AACCAACAGC 
CAAGTGCGGT GGGAGTACTG TAAGATACCG TCCTGTGACT CCTCCCCAGT ATCCACGGAA 
CAATTGGCTC CCACAGCACC ACCTGAGCTA ACCCCTGTGG TCCAGGACTG CTACCATGGT 
GATGGACAGA GCTACCGAGG CACATCCTCC ACCACCACCA CAGGAAAGAA GTGTCAGTCT 
TGGTCATCTA TGACACCACA CCGGCACCAG AAGACCCCAG AAAACTACCC AAATGCTGGC 
CTGACAATGA ACTACTGCAG GAATCCAGAT GCCGATAAAG GCCCCTGGTG TTTTACCACA 
GACCCCAGCG TCAGGTGGGA GTACTGCAAC CTGAAAAAAT GCTCAGGAAC AGAAGCGAGT 
GTTGTAGCAC CTCCGCCTGT TGTCCTGCTT CCAGATGTAG AGACTCCTTC CGAAGAAGAC 
TGTATGTTTG GGAATGGGAA AGGATACCGA GGCAAGAGGG CGACCACTGT TACTGGGACG 
CCATGCCAGG ACTGGGCTGC CCAGGAGCCC CATAGACACA GCATTTTCAC TCCAGAGACA 
AATCCACGGG CGGGTCTGGA AAAAAATTAC TGCCGTAACC CTGATGGTGA TGTAGGTGGT 
CCCTGGTGCT ACACGACAAA TCCAAGAAAA CTTTACGACT ACTGTGATGT CCCTCAGTGT 
GCGGCCCCTT CATTTGATTG TGGGAAGCCT CAAGTGGAGC CGAAGAAATG TCCTGGAAGG 
GTTGTAGGGG GGTGTGTGGC CCACCCACAT TCCTGGCCCT GGCAAGTCAG TCTTAGAACA 
AGGTTTGGAA TGCACTTCTG TGGAGGCACC TTGATATCCC CAGAGTGGGT GTTGACTGCT 
GCCCACTGCT TGGAGAAGTC CCCAAGGCCT TCATCCTACA AGGTCATCCT GGGTGCACAC 
CAAGAAGTGA ATCTCGAACC GCATGTTCAG GAAATAGAAG TGTCTAGGCT GTTCTTGGAG 
CCCACACGAA AAGATATTGC CTTGCTAAAG CTAAGCAGTC CTGCCGTCAT CACTGACAAA 
GTAATCCCAG CTTGTCTGCC ATCCCCAAAT TATGTGGTCG CTGACCGGAC CGAATGTTTC 
ATCACTGGCT GGGGAGAAAC CCAAGGTACT TTTGGAGCTG GCCTTCTCAA GGAAGCCCAG 
CTCCCTGTGA TTGAGAATAA AGTGTGCAAT CGCTATGAGT TTCTGAATGG AAGAGTCCAA 
TCCACCGAAC TCTGTGCTGG GCATTTGGCC GGAGGCACTG ACAGTTGCCA GGGTGACAGT 
GGAGGTCCTC TGGTTTGCTT CGAGAAGGAC AAATACATTT TACAAGGAGT CACTTCTTGG 
GGTCTTGGCT GTGCACGCCC CAATAAGCCT GGTGTCTATG TTCGTGTTTC AAGGTTTGTT 
ACTTGGATTG AGGGAGTGAT GAGAAATAAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000292.1
CDS	113..2545
Translation	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN

Target ORF information:

RefSeq Version	NM_000301.3
Organism	Homo sapiens(human)
Definition	Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000301.3

ORF Insert Sequence:

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC 
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT 
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGATT CTCACCTGCT 
ACACACCCCT CAGAGGGACT GGAGGAGAAC TACTGCAGGA ATCCAGACAA CGATCCGCAG 
GGGCCCTGGT GCTATACTAC TGATCCAGAA AAGAGATATG ACTACTGCGA CATTCTTGAG 
TGTGAAGAGG AATGTATGCA TTGCAGTGGA GAAAACTATG ACGGCAAAAT TTCCAAGACC 
ATGTCTGGAC TGGAATGCCA GGCCTGGGAC TCTCAGAGCC CACACGCTCA TGGATACATT 
CCTTCCAAAT TTCCAAACAA GAACCTGAAG AAGAATTACT GTCGTAACCC CGATAGGGAG 
CTGCGGCCTT GGTGTTTCAC CACCGACCCC AACAAGCGCT GGGAACTTTG TGACATCCCC 
CGCTGCACAA CACCTCCACC ATCTTCTGGT CCCACCTACC AGTGTCTGAA GGGAACAGGT 
GAAAACTATC GCGGGAATGT GGCTGTTACC GTGTCCGGGC ACACCTGTCA GCACTGGAGT 
GCACAGACCC CTCACACACA TAACAGGACA CCAGAAAACT TCCCCTGCAA AAATTTGGAT 
GAAAACTACT GCCGCAATCC TGACGGAAAA AGGGCCCCAT GGTGCCATAC AACCAACAGC 
CAAGTGCGGT GGGAGTACTG TAAGATACCG TCCTGTGACT CCTCCCCAGT ATCCACGGAA 
CAATTGGCTC CCACAGCACC ACCTGAGCTA ACCCCTGTGG TCCAGGACTG CTACCATGGT 
GATGGACAGA GCTACCGAGG CACATCCTCC ACCACCACCA CAGGAAAGAA GTGTCAGTCT 
TGGTCATCTA TGACACCACA CCGGCACCAG AAGACCCCAG AAAACTACCC AAATGCTGGC 
CTGACAATGA ACTACTGCAG GAATCCAGAT GCCGATAAAG GCCCCTGGTG TTTTACCACA 
GACCCCAGCG TCAGGTGGGA GTACTGCAAC CTGAAAAAAT GCTCAGGAAC AGAAGCGAGT 
GTTGTAGCAC CTCCGCCTGT TGTCCTGCTT CCAGATGTAG AGACTCCTTC CGAAGAAGAC 
TGTATGTTTG GGAATGGGAA AGGATACCGA GGCAAGAGGG CGACCACTGT TACTGGGACG 
CCATGCCAGG ACTGGGCTGC CCAGGAGCCC CATAGACACA GCATTTTCAC TCCAGAGACA 
AATCCACGGG CGGGTCTGGA AAAAAATTAC TGCCGTAACC CTGATGGTGA TGTAGGTGGT 
CCCTGGTGCT ACACGACAAA TCCAAGAAAA CTTTACGACT ACTGTGATGT CCCTCAGTGT 
GCGGCCCCTT CATTTGATTG TGGGAAGCCT CAAGTGGAGC CGAAGAAATG TCCTGGAAGG 
GTTGTAGGGG GGTGTGTGGC CCACCCACAT TCCTGGCCCT GGCAAGTCAG TCTTAGAACA 
AGGTTTGGAA TGCACTTCTG TGGAGGCACC TTGATATCCC CAGAGTGGGT GTTGACTGCT 
GCCCACTGCT TGGAGAAGTC CCCAAGGCCT TCATCCTACA AGGTCATCCT GGGTGCACAC 
CAAGAAGTGA ATCTCGAACC GCATGTTCAG GAAATAGAAG TGTCTAGGCT GTTCTTGGAG 
CCCACACGAA AAGATATTGC CTTGCTAAAG CTAAGCAGTC CTGCCGTCAT CACTGACAAA 
GTAATCCCAG CTTGTCTGCC ATCCCCAAAT TATGTGGTCG CTGACCGGAC CGAATGTTTC 
ATCACTGGCT GGGGAGAAAC CCAAGGTACT TTTGGAGCTG GCCTTCTCAA GGAAGCCCAG 
CTCCCTGTGA TTGAGAATAA AGTGTGCAAT CGCTATGAGT TTCTGAATGG AAGAGTCCAA 
TCCACCGAAC TCTGTGCTGG GCATTTGGCC GGAGGCACTG ACAGTTGCCA GGGTGACAGT 
GGAGGTCCTC TGGTTTGCTT CGAGAAGGAC AAATACATTT TACAAGGAGT CACTTCTTGG 
GGTCTTGGCT GTGCACGCCC CAATAAGCCT GGTGTCTATG TTCGTGTTTC AAGGTTTGTT 
ACTTGGATTG AGGGAGTGAT GAGAAATAAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLG ( NM_000301.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000292.1 Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22912
Clone ID Related Accession (Same CDS sequence)	NM_000301.4 , NM_000301.3
Accession Version	NM_000301.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-23
Organism	Homo sapiens(human)
Product	plasminogen isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL109933.25. On Nov 21, 2019 this sequence version replaced NM_000301.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK312966.1, X05199.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC 
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT 
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGATT CTCACCTGCT 
ACACACCCCT CAGAGGGACT GGAGGAGAAC TACTGCAGGA ATCCAGACAA CGATCCGCAG 
GGGCCCTGGT GCTATACTAC TGATCCAGAA AAGAGATATG ACTACTGCGA CATTCTTGAG 
TGTGAAGAGG AATGTATGCA TTGCAGTGGA GAAAACTATG ACGGCAAAAT TTCCAAGACC 
ATGTCTGGAC TGGAATGCCA GGCCTGGGAC TCTCAGAGCC CACACGCTCA TGGATACATT 
CCTTCCAAAT TTCCAAACAA GAACCTGAAG AAGAATTACT GTCGTAACCC CGATAGGGAG 
CTGCGGCCTT GGTGTTTCAC CACCGACCCC AACAAGCGCT GGGAACTTTG TGACATCCCC 
CGCTGCACAA CACCTCCACC ATCTTCTGGT CCCACCTACC AGTGTCTGAA GGGAACAGGT 
GAAAACTATC GCGGGAATGT GGCTGTTACC GTGTCCGGGC ACACCTGTCA GCACTGGAGT 
GCACAGACCC CTCACACACA TAACAGGACA CCAGAAAACT TCCCCTGCAA AAATTTGGAT 
GAAAACTACT GCCGCAATCC TGACGGAAAA AGGGCCCCAT GGTGCCATAC AACCAACAGC 
CAAGTGCGGT GGGAGTACTG TAAGATACCG TCCTGTGACT CCTCCCCAGT ATCCACGGAA 
CAATTGGCTC CCACAGCACC ACCTGAGCTA ACCCCTGTGG TCCAGGACTG CTACCATGGT 
GATGGACAGA GCTACCGAGG CACATCCTCC ACCACCACCA CAGGAAAGAA GTGTCAGTCT 
TGGTCATCTA TGACACCACA CCGGCACCAG AAGACCCCAG AAAACTACCC AAATGCTGGC 
CTGACAATGA ACTACTGCAG GAATCCAGAT GCCGATAAAG GCCCCTGGTG TTTTACCACA 
GACCCCAGCG TCAGGTGGGA GTACTGCAAC CTGAAAAAAT GCTCAGGAAC AGAAGCGAGT 
GTTGTAGCAC CTCCGCCTGT TGTCCTGCTT CCAGATGTAG AGACTCCTTC CGAAGAAGAC 
TGTATGTTTG GGAATGGGAA AGGATACCGA GGCAAGAGGG CGACCACTGT TACTGGGACG 
CCATGCCAGG ACTGGGCTGC CCAGGAGCCC CATAGACACA GCATTTTCAC TCCAGAGACA 
AATCCACGGG CGGGTCTGGA AAAAAATTAC TGCCGTAACC CTGATGGTGA TGTAGGTGGT 
CCCTGGTGCT ACACGACAAA TCCAAGAAAA CTTTACGACT ACTGTGATGT CCCTCAGTGT 
GCGGCCCCTT CATTTGATTG TGGGAAGCCT CAAGTGGAGC CGAAGAAATG TCCTGGAAGG 
GTTGTAGGGG GGTGTGTGGC CCACCCACAT TCCTGGCCCT GGCAAGTCAG TCTTAGAACA 
AGGTTTGGAA TGCACTTCTG TGGAGGCACC TTGATATCCC CAGAGTGGGT GTTGACTGCT 
GCCCACTGCT TGGAGAAGTC CCCAAGGCCT TCATCCTACA AGGTCATCCT GGGTGCACAC 
CAAGAAGTGA ATCTCGAACC GCATGTTCAG GAAATAGAAG TGTCTAGGCT GTTCTTGGAG 
CCCACACGAA AAGATATTGC CTTGCTAAAG CTAAGCAGTC CTGCCGTCAT CACTGACAAA 
GTAATCCCAG CTTGTCTGCC ATCCCCAAAT TATGTGGTCG CTGACCGGAC CGAATGTTTC 
ATCACTGGCT GGGGAGAAAC CCAAGGTACT TTTGGAGCTG GCCTTCTCAA GGAAGCCCAG 
CTCCCTGTGA TTGAGAATAA AGTGTGCAAT CGCTATGAGT TTCTGAATGG AAGAGTCCAA 
TCCACCGAAC TCTGTGCTGG GCATTTGGCC GGAGGCACTG ACAGTTGCCA GGGTGACAGT 
GGAGGTCCTC TGGTTTGCTT CGAGAAGGAC AAATACATTT TACAAGGAGT CACTTCTTGG 
GGTCTTGGCT GTGCACGCCC CAATAAGCCT GGTGTCTATG TTCGTGTTTC AAGGTTTGTT 
ACTTGGATTG AGGGAGTGAT GAGAAATAAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000292.1
CDS	64..2496
Translation	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFTCRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRELRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTEQLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN

Target ORF information:

RefSeq Version	NM_000301.4
Organism	Homo sapiens(human)
Definition	Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000301.4

ORF Insert Sequence:

ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG 
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC 
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG 
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC 
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT 
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGATT CTCACCTGCT 
ACACACCCCT CAGAGGGACT GGAGGAGAAC TACTGCAGGA ATCCAGACAA CGATCCGCAG 
GGGCCCTGGT GCTATACTAC TGATCCAGAA AAGAGATATG ACTACTGCGA CATTCTTGAG 
TGTGAAGAGG AATGTATGCA TTGCAGTGGA GAAAACTATG ACGGCAAAAT TTCCAAGACC 
ATGTCTGGAC TGGAATGCCA GGCCTGGGAC TCTCAGAGCC CACACGCTCA TGGATACATT 
CCTTCCAAAT TTCCAAACAA GAACCTGAAG AAGAATTACT GTCGTAACCC CGATAGGGAG 
CTGCGGCCTT GGTGTTTCAC CACCGACCCC AACAAGCGCT GGGAACTTTG TGACATCCCC 
CGCTGCACAA CACCTCCACC ATCTTCTGGT CCCACCTACC AGTGTCTGAA GGGAACAGGT 
GAAAACTATC GCGGGAATGT GGCTGTTACC GTGTCCGGGC ACACCTGTCA GCACTGGAGT 
GCACAGACCC CTCACACACA TAACAGGACA CCAGAAAACT TCCCCTGCAA AAATTTGGAT 
GAAAACTACT GCCGCAATCC TGACGGAAAA AGGGCCCCAT GGTGCCATAC AACCAACAGC 
CAAGTGCGGT GGGAGTACTG TAAGATACCG TCCTGTGACT CCTCCCCAGT ATCCACGGAA 
CAATTGGCTC CCACAGCACC ACCTGAGCTA ACCCCTGTGG TCCAGGACTG CTACCATGGT 
GATGGACAGA GCTACCGAGG CACATCCTCC ACCACCACCA CAGGAAAGAA GTGTCAGTCT 
TGGTCATCTA TGACACCACA CCGGCACCAG AAGACCCCAG AAAACTACCC AAATGCTGGC 
CTGACAATGA ACTACTGCAG GAATCCAGAT GCCGATAAAG GCCCCTGGTG TTTTACCACA 
GACCCCAGCG TCAGGTGGGA GTACTGCAAC CTGAAAAAAT GCTCAGGAAC AGAAGCGAGT 
GTTGTAGCAC CTCCGCCTGT TGTCCTGCTT CCAGATGTAG AGACTCCTTC CGAAGAAGAC 
TGTATGTTTG GGAATGGGAA AGGATACCGA GGCAAGAGGG CGACCACTGT TACTGGGACG 
CCATGCCAGG ACTGGGCTGC CCAGGAGCCC CATAGACACA GCATTTTCAC TCCAGAGACA 
AATCCACGGG CGGGTCTGGA AAAAAATTAC TGCCGTAACC CTGATGGTGA TGTAGGTGGT 
CCCTGGTGCT ACACGACAAA TCCAAGAAAA CTTTACGACT ACTGTGATGT CCCTCAGTGT 
GCGGCCCCTT CATTTGATTG TGGGAAGCCT CAAGTGGAGC CGAAGAAATG TCCTGGAAGG 
GTTGTAGGGG GGTGTGTGGC CCACCCACAT TCCTGGCCCT GGCAAGTCAG TCTTAGAACA 
AGGTTTGGAA TGCACTTCTG TGGAGGCACC TTGATATCCC CAGAGTGGGT GTTGACTGCT 
GCCCACTGCT TGGAGAAGTC CCCAAGGCCT TCATCCTACA AGGTCATCCT GGGTGCACAC 
CAAGAAGTGA ATCTCGAACC GCATGTTCAG GAAATAGAAG TGTCTAGGCT GTTCTTGGAG 
CCCACACGAA AAGATATTGC CTTGCTAAAG CTAAGCAGTC CTGCCGTCAT CACTGACAAA 
GTAATCCCAG CTTGTCTGCC ATCCCCAAAT TATGTGGTCG CTGACCGGAC CGAATGTTTC 
ATCACTGGCT GGGGAGAAAC CCAAGGTACT TTTGGAGCTG GCCTTCTCAA GGAAGCCCAG 
CTCCCTGTGA TTGAGAATAA AGTGTGCAAT CGCTATGAGT TTCTGAATGG AAGAGTCCAA 
TCCACCGAAC TCTGTGCTGG GCATTTGGCC GGAGGCACTG ACAGTTGCCA GGGTGACAGT 
GGAGGTCCTC TGGTTTGCTT CGAGAAGGAC AAATACATTT TACAAGGAGT CACTTCTTGG 
GGTCTTGGCT GTGCACGCCC CAATAAGCCT GGTGTCTATG TTCGTGTTTC AAGGTTTGTT 
ACTTGGATTG AGGGAGTGAT GAGAAATAAT TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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PLG cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

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見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

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