ATP6V1G2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATP6V1G2
Entrez Gene ID	534
Full Name	ATPase H+ transporting V1 subunit G2
Synonyms	ATP6G,ATP6G2,NG38,VMA10
General protein information	Preferred Names ATPase H+ transporting V1 subunit G2 Names V-type proton ATPase subunit G 2 ATPase, H+ transporting, lysosomal (vacuolar proton pump) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 H(+)-transporting two-sector ATPase, subunit G2 V-ATPase 13 kDa subunit 2 vacuolar ATP synthase subunit G 2 vacuolar proton pump G subunit 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.33
Summary	This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene. [provided by RefSeq, Feb 2011].
Disorder MIM:	606853

mRNA and Protein(s)

mRNA	Protein	Name
NM_138282.3	NP_612139.1	V-type proton ATPase subunit G 2 isoform b
NM_001204078.2	NP_001191007.1	V-type proton ATPase subunit G 2 isoform c
NM_001204078.1	NP_001191007.1	V-type proton ATPase subunit G 2 isoform c
NM_138282.2	NP_612139.1	V-type proton ATPase subunit G 2 isoform b
NM_130463.3	NP_569730.1	V-type proton ATPase subunit G 2 isoform a
NM_130463.4	NP_569730.1	V-type proton ATPase subunit G 2 isoform a

Pathways from BioSystems

Homologies

Homo sapiens (human)	ATP6V1G2	NP_569730.1
	ATP6V1G2	NP_001040610.1
Mus musculus (house mouse)	Atp6v1g2	NP_075668.1
Xenopus tropicalis (tropical clawed frog)	atp6v1g2	NP_001072840.1
Rattus norvegicus (Norway rat)	Atp6v1g2	NP_997655.1
Bos taurus (cattle)	ATP6V1G2	NP_001069132.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001823	XP_321230.2
Pan troglodytes (chimpanzee)	ATP6V1G2	NP_001107639.1
Canis lupus familiaris (dog)	ATP6V1G2	NP_001014398.1
Drosophila melanogaster (fruit fly)	Vha13	NP_477437.1

Gene Ontology
Bibliography

Related articles in PubMed

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.
H?hn A, Sittig A, Jung T, Grimm S, Grune T
Free radical biology & medicine53(9)1760-9(2012 Nov)

Haplotype-specific gene expression profiles in a telomeric major histocompatibility complex gene cluster and susceptibility to autoimmune diseases.
Mewar D, Marinou I, Lee ME, Timms JM, Kilding R, Teare MD, Read RC, Wilson AG
Genes and immunity7(8)625-31(2006 Dec)

The haplotype block, NFKBIL1-ATP6V1G2-BAT1-MICB-MICA, within the class III-class I boundary region of the human major histocompatibility complex may control susceptibility to hepatitis C virus-associated dilated cardiomyopathy.
Shichi D, Kikkawa EF, Ota M, Katsuyama Y, Kimura A, Matsumori A, Kulski JK, Naruse TK, Inoko H
Tissue antigens66(3)200-8(2005 Sep)

Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.
Lehner B, Semple JI, Brown SE, Counsell D, Campbell RD, Sanderson CM
Genomics83(1)153-67(2004 Jan)

Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosis.
Smith AN, Borthwick KJ, Karet FE
Gene297(1-2)169-77(2002 Sep)

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The following ATP6V1G2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP6V1G2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06053	NM_138282.3 Latest version!	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05874	NM_130463.4 Latest version!	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu32348	NM_001204078.2 Latest version!	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu32348	NM_001204078.1	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06053	NM_138282.2	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu05874	NM_130463.3	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATP6V1G2 ( NM_138282.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_612139.1 Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06053
Clone ID Related Accession (Same CDS sequence)	NM_138282.3 , NM_138282.2
Accession Version	NM_138282.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 234bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit G 2 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA401769.1 and AL662801.7. On Nov 21, 2018 this sequence version replaced NM_138282.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1123564.1, SRR3476690.214045.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGTGG AGCAATACCG CAGAGAGCGA GAGCACGAAT TCCAGAGCAA GCAGCAGGCG 
GCCATGGGCT CCCAGGGGAA CCTGTCTGCT GAGGTGGAGC AGGCTACAAG GCGCCAGGTG 
CAGGGCATGC AGAGCTCCCA GCAGAGAAAC CGAGAGCGTG TCCTGGCCCA GCTTCTTGGC 
ATGGTCTGCG ACGTCAGGCC CCAGGTCCAC CCCAACTACC GGATTTCTGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612139.1
CDS	153..386
Translation	MEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA

Target ORF information:

RefSeq Version	NM_138282.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138282.3

ORF Insert Sequence:

ATGGAGGTGG AGCAATACCG CAGAGAGCGA GAGCACGAAT TCCAGAGCAA GCAGCAGGCG 
GCCATGGGCT CCCAGGGGAA CCTGTCTGCT GAGGTGGAGC AGGCTACAAG GCGCCAGGTG 
CAGGGCATGC AGAGCTCCCA GCAGAGAAAC CGAGAGCGTG TCCTGGCCCA GCTTCTTGGC 
ATGGTCTGCG ACGTCAGGCC CCAGGTCCAC CCCAACTACC GGATTTCTGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V1G2 ( NM_138282.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_612139.1 Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06053
Clone ID Related Accession (Same CDS sequence)	NM_138282.3 , NM_138282.2
Accession Version	NM_138282.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 234bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit G 2 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA401769.1, BP195978.1, BC068023.1 and C20601.1. On Feb 11, 2011 this sequence version replaced NM_138282.1. Transcript Variant: This variant (2) lacks a segment of the 5' UTR and 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (b), also known as ATP6Galt, is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AA401769.1, SRR1660807.363450.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGTGG AGCAATACCG CAGAGAGCGA GAGCACGAAT TCCAGAGCAA GCAGCAGGCG 
GCCATGGGCT CCCAGGGGAA CCTGTCTGCT GAGGTGGAGC AGGCTACAAG GCGCCAGGTG 
CAGGGCATGC AGAGCTCCCA GCAGAGAAAC CGAGAGCGTG TCCTGGCCCA GCTTCTTGGC 
ATGGTCTGCG ACGTCAGGCC CCAGGTCCAC CCCAACTACC GGATTTCTGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612139.1
CDS	259..492
Translation	MEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA

Target ORF information:

RefSeq Version	NM_138282.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138282.2

ORF Insert Sequence:

ATGGAGGTGG AGCAATACCG CAGAGAGCGA GAGCACGAAT TCCAGAGCAA GCAGCAGGCG 
GCCATGGGCT CCCAGGGGAA CCTGTCTGCT GAGGTGGAGC AGGCTACAAG GCGCCAGGTG 
CAGGGCATGC AGAGCTCCCA GCAGAGAAAC CGAGAGCGTG TCCTGGCCCA GCTTCTTGGC 
ATGGTCTGCG ACGTCAGGCC CCAGGTCCAC CCCAACTACC GGATTTCTGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V1G2 ( NM_130463.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_569730.1 Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05874
Clone ID Related Accession (Same CDS sequence)	NM_130463.3 , NM_130463.4
Accession Version	NM_130463.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit G 2 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA401769.1, BC119726.1, BC068023.1 and C20601.1. On Feb 11, 2011 this sequence version replaced NM_130463.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.312046.1, SRR1660805.376067.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCAAA GGAGGAGGCA 
CAGATGGAGG TGGAGCAATA CCGCAGAGAG CGAGAGCACG AATTCCAGAG CAAGCAGCAG 
GCGGCCATGG GCTCCCAGGG GAACCTGTCT GCTGAGGTGG AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569730.1
CDS	290..646
Translation	MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA

Target ORF information:

RefSeq Version	NM_130463.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130463.3

ORF Insert Sequence:

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCAAA GGAGGAGGCA 
CAGATGGAGG TGGAGCAATA CCGCAGAGAG CGAGAGCACG AATTCCAGAG CAAGCAGCAG 
GCGGCCATGG GCTCCCAGGG GAACCTGTCT GCTGAGGTGG AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V1G2 ( NM_130463.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_569730.1 Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05874
Clone ID Related Accession (Same CDS sequence)	NM_130463.3 , NM_130463.4
Accession Version	NM_130463.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit G 2 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA129116.1, BC068023.2 and AL662801.7. On Nov 21, 2018 this sequence version replaced NM_130463.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.80342.1, SRR5189655.203385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCAAA GGAGGAGGCA 
CAGATGGAGG TGGAGCAATA CCGCAGAGAG CGAGAGCACG AATTCCAGAG CAAGCAGCAG 
GCGGCCATGG GCTCCCAGGG GAACCTGTCT GCTGAGGTGG AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569730.1
CDS	50..406
Translation	MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVEQYRREREHEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA

Target ORF information:

RefSeq Version	NM_130463.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130463.4

ORF Insert Sequence:

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCAAA GGAGGAGGCA 
CAGATGGAGG TGGAGCAATA CCGCAGAGAG CGAGAGCACG AATTCCAGAG CAAGCAGCAG 
GCGGCCATGG GCTCCCAGGG GAACCTGTCT GCTGAGGTGG AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V1G2 ( NM_001204078.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191007.1 Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu32348
Clone ID Related Accession (Same CDS sequence)	NM_001204078.2 , NM_001204078.1
Accession Version	NM_001204078.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit G 2 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC047791.1 and AL662801.7. On Nov 21, 2018 this sequence version replaced NM_001204078.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047791.1, BQ959563.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191007.1
CDS	50..286
Translation	MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA

Target ORF information:

RefSeq Version	NM_001204078.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204078.2

ORF Insert Sequence:

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATP6V1G2 ( NM_001204078.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191007.1 Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu32348
Clone ID Related Accession (Same CDS sequence)	NM_001204078.2 , NM_001204078.1
Accession Version	NM_001204078.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	V-type proton ATPase subunit G 2 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA401769.1, BC119726.1, BC047791.1, BC068023.1 and C20601.1. Transcript Variant: This variant (3) uses two alternate splice sites that result in the loss of an in-frame segment in the central coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047791.1, BQ959563.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191007.1
CDS	290..526
Translation	MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRISA

Target ORF information:

RefSeq Version	NM_001204078.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase H+ transporting V1 subunit G2 (ATP6V1G2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204078.1

ORF Insert Sequence:

ATGGCCAGTC AGTCCCAAGG TATCCAGCAG CTTCTGCAAG CTGAGAAGCG GGCAGCTGAG 
AAGGTGGCAG ATGCCAGAAA GAGGAAGGCC CGGCGACTGA AGCAGGCTAC AAGGCGCCAG 
GTGCAGGGCA TGCAGAGCTC CCAGCAGAGA AACCGAGAGC GTGTCCTGGC CCAGCTTCTT 
GGCATGGTCT GCGACGTCAG GCCCCAGGTC CACCCCAACT ACCGGATTTC TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.
Free radical biology & medicine53(9)1760-9(2012 Nov)
H?hn A,Sittig A,Jung T,Grimm S,Grune T

Haplotype-specific gene expression profiles in a telomeric major histocompatibility complex gene cluster and susceptibility to autoimmune diseases.
Genes and immunity7(8)625-31(2006 Dec)
Mewar D,Marinou I,Lee ME,Timms JM,Kilding R,Teare MD,Read RC,Wilson AG

The haplotype block, NFKBIL1-ATP6V1G2-BAT1-MICB-MICA, within the class III-class I boundary region of the human major histocompatibility complex may control susceptibility to hepatitis C virus-associated dilated cardiomyopathy.
Tissue antigens66(3)200-8(2005 Sep)
Shichi D,Kikkawa EF,Ota M,Katsuyama Y,Kimura A,Matsumori A,Kulski JK,Naruse TK,Inoko H

Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.
Genomics83(1)153-67(2004 Jan)
Lehner B,Semple JI,Brown SE,Counsell D,Campbell RD,Sanderson CM

Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosis.
Gene297(1-2)169-77(2002 Sep)
Smith AN,Borthwick KJ,Karet FE

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ATP6V1G2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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