CHIC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CHIC1
Entrez Gene ID	53344
Full Name	cysteine rich hydrophobic domain 1
Synonyms	BRX
General protein information	Preferred Names cysteine rich hydrophobic domain 1 Names cysteine-rich hydrophobic domain-containing protein 1 brain X-linked protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq13.2
Summary	This gene encodes a cysteine-rich hydrophobic (CHIC) domain-containing protein, and is one of the few protein-coding genes found near the X-inactivation center. Studies in mouse indicate that the mouse ortholog of this gene is subject to X-inactivation in mouse. Experiments with other CHIC domain-containing family members show that the cysteine residues are palmitoylated post-translationally, resulting in membrane association. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017].
Disorder MIM:	300922

mRNA and Protein(s)

mRNA	Protein	Name
XM_017029583.1	XP_016885072.1	cysteine-rich hydrophobic domain-containing protein 1 isoform X2
NM_001039840.2	NP_001034929.2	cysteine-rich hydrophobic domain-containing protein 1 isoform 1
NM_001300884.1	NP_001287813.1	cysteine-rich hydrophobic domain-containing protein 1 isoform 2
NM_001039840.3	NP_001034929.2	cysteine-rich hydrophobic domain-containing protein 1 isoform 1
XM_017029584.1	XP_016885073.1	cysteine-rich hydrophobic domain-containing protein 1 isoform X3
XM_017029582.1	XP_016885071.1	cysteine-rich hydrophobic domain-containing protein 1 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CHIC1	NP_001034929.2
Xenopus tropicalis (tropical clawed frog)	LOC101732617	XP_004916890.1
Pan troglodytes (chimpanzee)	CHIC1	XP_521135.3
Canis lupus familiaris (dog)	CHIC1	XP_003435625.1
Bos taurus (cattle)	CHIC1	NP_001193124.1
Danio rerio (zebrafish)	chic1	NP_001188392.1
Rattus norvegicus (Norway rat)	Chic1	XP_001056014.2
Caenorhabditis elegans (roundworm)	tag-266	NP_497227.1
	CHIC1	XP_001095379.1
Mus musculus (house mouse)	Chic1	NP_033897.1
Gallus gallus (chicken)	CHIC1	NP_001026293.1

Gene Ontology
Bibliography

Related articles in PubMed

The DNA sequence of the human X chromosome.
Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Gl?ckner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, M?ller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR
Nature434(7031)325-37(2005 Mar)

A new family of small, palmitoylated, membrane-associated proteins, characterized by the presence of a cysteine-rich hydrophobic motif.
Cools J, Mentens N, Marynen P
FEBS letters492(3)204-9(2001 Mar)

Localization and expression analysis of a novel conserved brain expressed transcript, Brx/BRX, lying within the Xic/XIC candidate region.
Simmler MC, Heard E, Rougeulle C, Cruaud C, Weissenbach J, Avner P
Mammalian genome : official journal of the International Mammalian Genome Society8(10)760-6(1997 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CHIC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHIC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24674	NM_001039840.3 Latest version!	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu99338	XM_017029583.1 Latest version!	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu54174	NM_001300884.1 Latest version!	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu99337	XM_017029582.1 Latest version!	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu99339	XM_017029584.1 Latest version!	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu24674	NM_001039840.2	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CHIC1 ( NM_001039840.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034929.2 Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24674
Clone ID Related Accession (Same CDS sequence)	NM_001039840.2 , NM_001039840.3
Accession Version	NM_001039840.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-29
Organism	Homo sapiens(Human)
Product	cysteine-rich hydrophobic domain-containing protein 1 isoform 1
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC382882.1, BC127728.1 and AL356513.15. On Aug 4, 2007 this sequence version replaced NM_001039840.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.176750.1, SRR1660809.251167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAACC AGAAGATCAA TTCAGAAGTT AATAGAATGG 
GAAAATAACA GATTATATCA CAAGCTTGCT TTGCACTGGA AGTTGACTAA GAGGAAATGT 
GAAACTAGCA ATATGATGGA GTATGTAATA CTAATAGAAT TCTTACCAAA ATATCCCATA 
TTCCGACCTG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034929.2
CDS	138..812
Translation	MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD

Target ORF information:

RefSeq Version	NM_001039840.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039840.2

ORF Insert Sequence:

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAACC AGAAGATCAA TTCAGAAGTT AATAGAATGG 
GAAAATAACA GATTATATCA CAAGCTTGCT TTGCACTGGA AGTTGACTAA GAGGAAATGT 
GAAACTAGCA ATATGATGGA GTATGTAATA CTAATAGAAT TCTTACCAAA ATATCCCATA 
TTCCGACCTG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHIC1 ( NM_001039840.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034929.2 Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24674
Clone ID Related Accession (Same CDS sequence)	NM_001039840.2 , NM_001039840.3
Accession Version	NM_001039840.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	cysteine-rich hydrophobic domain-containing protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC382882.1, BC127728.1, AL356513.15 and AI580377.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2017 this sequence version replaced NM_001039840.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.176750.1, SRR1660809.251167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAACC AGAAGATCAA TTCAGAAGTT AATAGAATGG 
GAAAATAACA GATTATATCA CAAGCTTGCT TTGCACTGGA AGTTGACTAA GAGGAAATGT 
GAAACTAGCA ATATGATGGA GTATGTAATA CTAATAGAAT TCTTACCAAA ATATCCCATA 
TTCCGACCTG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034929.2
CDS	138..812
Translation	MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD

Target ORF information:

RefSeq Version	NM_001039840.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039840.3

ORF Insert Sequence:

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAACC AGAAGATCAA TTCAGAAGTT AATAGAATGG 
GAAAATAACA GATTATATCA CAAGCTTGCT TTGCACTGGA AGTTGACTAA GAGGAAATGT 
GAAACTAGCA ATATGATGGA GTATGTAATA CTAATAGAAT TCTTACCAAA ATATCCCATA 
TTCCGACCTG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHIC1 ( XM_017029583.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885072.1 Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu99338
Clone ID Related Accession (Same CDS sequence)	XM_017029583.1
Accession Version	XM_017029583.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cysteine-rich hydrophobic domain-containing protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATAGAG GCAAGGGAGA AAAGAAGTTG AATATTGCTG TTGGAGAGGT GGCCCCAGAA 
GAATTTAAAA CCAGCATTGG CCGTGTGAAT GCATGTTTGA AAAAGGCTCT CCCGGTCAAT 
GTGAAATGGC TGCTGTGTGG TTGTCTCTGC TGCTGTTGCA CACTGGGTTG CAGCCTATGG 
CCTGTTATTT GTCTCAACAA AAGAACCAGA AGATCAATTC AGAAGTTAAT AGAATGGGAA 
AATAACAGAT TATATCACAA GCTTGCTTTG CACTGGAAGT TGACTAAGAG GAAATGTGAA 
ACTAGCAATA TGATGGAGTA TGTAATACTA ATAGAATTCT TACCAAAATA TCCCATATTC 
CGACCTGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885072.1
CDS	122..493
Translation	MDRGKGEKKLNIAVGEVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD

Target ORF information:

RefSeq Version	XM_017029583.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029583.1

ORF Insert Sequence:

ATGGATAGAG GCAAGGGAGA AAAGAAGTTG AATATTGCTG TTGGAGAGGT GGCCCCAGAA 
GAATTTAAAA CCAGCATTGG CCGTGTGAAT GCATGTTTGA AAAAGGCTCT CCCGGTCAAT 
GTGAAATGGC TGCTGTGTGG TTGTCTCTGC TGCTGTTGCA CACTGGGTTG CAGCCTATGG 
CCTGTTATTT GTCTCAACAA AAGAACCAGA AGATCAATTC AGAAGTTAAT AGAATGGGAA 
AATAACAGAT TATATCACAA GCTTGCTTTG CACTGGAAGT TGACTAAGAG GAAATGTGAA 
ACTAGCAATA TGATGGAGTA TGTAATACTA ATAGAATTCT TACCAAAATA TCCCATATTC 
CGACCTGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHIC1 ( NM_001300884.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001287813.1 Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu54174
Clone ID Related Accession (Same CDS sequence)	NM_001300884.1
Accession Version	NM_001300884.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 615bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	cysteine-rich hydrophobic domain-containing protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL358796.43, BC127727.1 and AL356513.15. On Jul 16, 2014 this sequence version replaced XM_005262276.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region comapred to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CR936642.1, SRR1660803.172667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAACC AGAAGATCAA TTCAGAAGTT AATAGAATGG 
GAAAATAACA GATTATATCA CAAGGTAATA CTAATAGAAT TCTTACCAAA ATATCCCATA 
TTCCGACCTG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287813.1
CDS	138..752
Translation	MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKVILIEFLPKYPIFRPD

Target ORF information:

RefSeq Version	NM_001300884.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300884.1

ORF Insert Sequence:

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAACC AGAAGATCAA TTCAGAAGTT AATAGAATGG 
GAAAATAACA GATTATATCA CAAGGTAATA CTAATAGAAT TCTTACCAAA ATATCCCATA 
TTCCGACCTG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHIC1 ( XM_017029582.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885071.1 Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu99337
Clone ID Related Accession (Same CDS sequence)	XM_017029582.1
Accession Version	XM_017029582.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cysteine-rich hydrophobic domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAGTG TGGACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885071.1
CDS	241..759
Translation	MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRVWT

Target ORF information:

RefSeq Version	XM_017029582.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029582.1

ORF Insert Sequence:

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GGTGGCCCCA 
GAAGAATTTA AAACCAGCAT TGGCCGTGTG AATGCATGTT TGAAAAAGGC TCTCCCGGTC 
AATGTGAAAT GGCTGCTGTG TGGTTGTCTC TGCTGCTGTT GCACACTGGG TTGCAGCCTA 
TGGCCTGTTA TTTGTCTCAA CAAAAGAGTG TGGACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHIC1 ( XM_017029584.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885073.1 Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu99339
Clone ID Related Accession (Same CDS sequence)	XM_017029584.1
Accession Version	XM_017029584.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cysteine-rich hydrophobic domain-containing protein 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GAAATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885073.1
CDS	241..600
Translation	MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKKF

Target ORF information:

RefSeq Version	XM_017029584.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cysteine rich hydrophobic domain 1 (CHIC1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029584.1

ORF Insert Sequence:

ATGAGCATCC TGCTGCCCAA CATGGCGGAG TTCGACACCA TCTCGGAACT GGAGGAGGAG 
GAGGAAGAAG AAGCGGCAAC GTCGTCGTCG TCGCCGTCGT CGTCGTCGTC GGTATCTGGG 
CCCGACGATG ACGAGGAGGA TGAGGAGGAA GAGGAGGAAG AGGAGGAGGA GGAAGAAGAG 
GAGGAGGAGG AAGAGGAGGA GGAAGCGCCG CCCCCGCCTC GGGTAGTGAG CGAGGAGCAT 
CTGCGGAGAT ATGCTCCCGA CCCTGTATTA GTGCGGGGTG CCGGCCACAT CACTGTGTTT 
GGCTTGAGCA ACAAGTTTGA TACTGAATTT CCCTCCGTTC TAACAGGGAA GAAATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The DNA sequence of the human X chromosome.
Nature434(7031)325-37(2005 Mar)
Ross MT,Grafham DV,Coffey AJ,Scherer S,McLay K,Muzny D,Platzer M,Howell GR,Burrows C,Bird CP,Frankish A,Lovell FL,Howe KL,Ashurst JL,Fulton RS,Sudbrak R,Wen G,Jones MC,Hurles ME,Andrews TD,Scott CE,Searle S,Ramser J,Whittaker A,Deadman R,Carter NP,Hunt SE,Chen R,Cree A,Gunaratne P,Havlak P,Hodgson A,Metzker ML,Richards S,Scott G,Steffen D,Sodergren E,Wheeler DA,Worley KC,Ainscough R,Ambrose KD,Ansari-Lari MA,Aradhya S,Ashwell RI,Babbage AK,Bagguley CL,Ballabio A,Banerjee R,Barker GE,Barlow KF,Barrett IP,Bates KN,Beare DM,Beasley H,Beasley O,Beck A,Bethel G,Blechschmidt K,Brady N,Bray-Allen S,Bridgeman AM,Brown AJ,Brown MJ,Bonnin D,Bruford EA,Buhay C,Burch P,Burford D,Burgess J,Burrill W,Burton J,Bye JM,Carder C,Carrel L,Chako J,Chapman JC,Chavez D,Chen E,Chen G,Chen Y,Chen Z,Chinault C,Ciccodicola A,Clark SY,Clarke G,Clee CM,Clegg S,Clerc-Blankenburg K,Clifford K,Cobley V,Cole CG,Conquer JS,Corby N,Connor RE,David R,Davies J,Davis C,Davis J,Delgado O,Deshazo D,Dhami P,Ding Y,Dinh H,Dodsworth S,Draper H,Dugan-Rocha S,Dunham A,Dunn M,Durbin KJ,Dutta I,Eades T,Ellwood M,Emery-Cohen A,Errington H,Evans KL,Faulkner L,Francis F,Frankland J,Fraser AE,Galgoczy P,Gilbert J,Gill R,Gl?ckner G,Gregory SG,Gribble S,Griffiths C,Grocock R,Gu Y,Gwilliam R,Hamilton C,Hart EA,Hawes A,Heath PD,Heitmann K,Hennig S,Hernandez J,Hinzmann B,Ho S,Hoffs M,Howden PJ,Huckle EJ,Hume J,Hunt PJ,Hunt AR,Isherwood J,Jacob L,Johnson D,Jones S,de Jong PJ,Joseph SS,Keenan S,Kelly S,Kershaw JK,Khan Z,Kioschis P,Klages S,Knights AJ,Kosiura A,Kovar-Smith C,Laird GK,Langford C,Lawlor S,Leversha M,Lewis L,Liu W,Lloyd C,Lloyd DM,Loulseged H,Loveland JE,Lovell JD,Lozado R,Lu J,Lyne R,Ma J,Maheshwari M,Matthews LH,McDowall J,McLaren S,McMurray A,Meidl P,Meitinger T,Milne S,Miner G,Mistry SL,Morgan M,Morris S,M?ller I,Mullikin JC,Nguyen N,Nordsiek G,Nyakatura G,O'Dell CN,Okwuonu G,Palmer S,Pandian R,Parker D,Parrish J,Pasternak S,Patel D,Pearce AV,Pearson DM,Pelan SE,Perez L,Porter KM,Ramsey Y,Reichwald K,Rhodes S,Ridler KA,Schlessinger D,Schueler MG,Sehra HK,Shaw-Smith C,Shen H,Sheridan EM,Shownkeen R,Skuce CD,Smith ML,Sotheran EC,Steingruber HE,Steward CA,Storey R,Swann RM,Swarbreck D,Tabor PE,Taudien S,Taylor T,Teague B,Thomas K,Thorpe A,Timms K,Tracey A,Trevanion S,Tromans AC,d'Urso M,Verduzco D,Villasana D,Waldron L,Wall M,Wang Q,Warren J,Warry GL,Wei X,West A,Whitehead SL,Whiteley MN,Wilkinson JE,Willey DL,Williams G,Williams L,Williamson A,Williamson H,Wilming L,Woodmansey RL,Wray PW,Yen J,Zhang J,Zhou J,Zoghbi H,Zorilla S,Buck D,Reinhardt R,Poustka A,Rosenthal A,Lehrach H,Meindl A,Minx PJ,Hillier LW,Willard HF,Wilson RK,Waterston RH,Rice CM,Vaudin M,Coulson A,Nelson DL,Weinstock G,Sulston JE,Durbin R,Hubbard T,Gibbs RA,Beck S,Rogers J,Bentley DR

A new family of small, palmitoylated, membrane-associated proteins, characterized by the presence of a cysteine-rich hydrophobic motif.
FEBS letters492(3)204-9(2001 Mar)
Cools J,Mentens N,Marynen P

Localization and expression analysis of a novel conserved brain expressed transcript, Brx/BRX, lying within the Xic/XIC candidate region.
Mammalian genome : official journal of the International Mammalian Genome Society8(10)760-6(1997 Oct)
Simmler MC,Heard E,Rougeulle C,Cruaud C,Weissenbach J,Avner P

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CHIC1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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