BTBD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BTBD1
Entrez Gene ID	53339
Full Name	BTB domain containing 1
Synonyms	C15orf1,NS5ATP8
General protein information	Preferred Names BTB domain containing 1 Names BTB/POZ domain-containing protein 1 BTB (POZ) domain containing 1 HCV NS5A-transactivated protein 8 hepatitis C virus NS5A-transactivated protein 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q25.2
Summary	The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Disorder MIM:	608530

mRNA and Protein(s)

mRNA	Protein	Name
NM_025238.4	NP_079514.1	BTB/POZ domain-containing protein 1 isoform 1
NM_001011885.2	NP_001011885.1	BTB/POZ domain-containing protein 1 isoform 2
NM_001011885.1	NP_001011885.1	BTB/POZ domain-containing protein 1 isoform 2
NM_025238.3	NP_079514.1	BTB/POZ domain-containing protein 1 isoform 1

Pathways from BioSystems

Homologies

	BTBD1	XP_002804966.1
Homo sapiens (human)	BTBD1	NP_079514.1
Canis lupus familiaris (dog)	BTBD1	XP_005618450.1
Bos taurus (cattle)	BTBD1	NP_001091529.1
Mus musculus (house mouse)	Btbd1	NP_666305.2
Gallus gallus (chicken)	BTBD1	NP_001005819.1
Pan troglodytes (chimpanzee)	BTBD1	XP_001160707.1
Rattus norvegicus (Norway rat)	Btbd1	NP_001011932.1

Gene Ontology
Bibliography

Related articles in PubMed

Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions.
Muller M, Jacob Y, Jones L, Weiss A, Brino L, Chantier T, Lotteau V, Favre M, Demeret C
PLoS pathogens8(6)e1002761(2012)

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study.
Tsai FJ, Lee YC, Chang JS, Huang LM, Huang FY, Chiu NC, Chen MR, Chi H, Lee YJ, Chang LC, Liu YM, Wang HH, Chen CH, Chen YT, Wu JY
PloS one6(2)e16853(2011 Feb)

Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection.
Khurana B, Zhuang L, Moitra PK, Stantchev TS, Broder CC, Cutler ML, D'Arpa P
Virology journal7332(2010 Nov)

CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592.
Nicolas E, Poitelon Y, Chouery E, Salem N, Levy N, M?garban? A, Delague V
European journal of human genetics : EJHG18(10)1107-13(2010 Oct)

Search for cellular partners of human papillomavirus type 16 E2 protein.
Olejnik-Schmidt AK, Schmidt MT, Kedzia W, Go?dzicka-J?zefiak A
Archives of virology153(5)983-90(2008)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interaction of BTBD1 and BTBD2 with TOP1 requires TOP1 residues 236 and 237, the same residues required to enhance the infectivity of progeny virions when TOP1 is expressed in African Green Monkey producer cells.
Title: Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection.

BTBD1 is essential for myogenic differentiation
Title: The topoisomerase 1-interacting protein BTBD1 is essential for muscle cell differentiation.

subcellular colocalization of BTBD1 and BTBD2 to cytoplasmic bodies; TRIM5delta colocalized with BTBD1/2 and appeared to serve as a scaffold for the assembly of endogenous BTBD1/2 proteins
Title: BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta.

The following BTBD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BTBD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04433	NM_025238.4 Latest version!	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu04020	NM_001011885.2 Latest version!	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu04020	NM_001011885.1	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu04433	NM_025238.3	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BTBD1 ( NM_025238.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_079514.1 Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04433
Clone ID Related Accession (Same CDS sequence)	NM_025238.4 , NM_025238.3
Accession Version	NM_025238.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	BTB/POZ domain-containing protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI553790.1, BC028097.1 and AF257241.1. On May 17, 2019 this sequence version replaced NM_025238.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803617.63500.1, SRR1803617.257145.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261721.9/ ENSP00000261721.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATTCA CAGTTAATAG AAGGATCTCT 
ATAGTTGGAT TTGGCTTGTA TGGATCTATT CATGGCCCTA CAGATTATCA AGTGAATATA 
CAGATCATTG AATATGAGAA AAAGCAAACC CTGGGACAGA ATGATACCGG CTTTAGTTGT 
GATGGGACAG CTAACACATT CAGGGTCATG TTCAAGGAAC CCATAGAGAT CCTGCCCAAT 
GTGTGCTACA CAGCATGTGC AACACTCAAA GGTCCAGATT CCCACTATGG CACAAAAGGA 
TTGAAGAAAG TAGTGCATGA GACACCTGCT GCAAGCAAGA CTGTTTTTTT CTTTTTTAGT 
TCCCCTGGCA ATAATAATGG CACTTCAATA GAAGATGGAC AAATTCCAGA AATCATATTT 
TATACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079514.1
CDS	102..1550
Translation	MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRISIVGFGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCYTACATLKGPDSHYGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSIEDGQIPEIIFYT

Target ORF information:

RefSeq Version	NM_025238.4
Organism	Homo sapiens(human)
Definition	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025238.4

ORF Insert Sequence:

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATTCA CAGTTAATAG AAGGATCTCT 
ATAGTTGGAT TTGGCTTGTA TGGATCTATT CATGGCCCTA CAGATTATCA AGTGAATATA 
CAGATCATTG AATATGAGAA AAAGCAAACC CTGGGACAGA ATGATACCGG CTTTAGTTGT 
GATGGGACAG CTAACACATT CAGGGTCATG TTCAAGGAAC CCATAGAGAT CCTGCCCAAT 
GTGTGCTACA CAGCATGTGC AACACTCAAA GGTCCAGATT CCCACTATGG CACAAAAGGA 
TTGAAGAAAG TAGTGCATGA GACACCTGCT GCAAGCAAGA CTGTTTTTTT CTTTTTTAGT 
TCCCCTGGCA ATAATAATGG CACTTCAATA GAAGATGGAC AAATTCCAGA AATCATATTT 
TATACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BTBD1 ( NM_025238.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079514.1 Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04433
Clone ID Related Accession (Same CDS sequence)	NM_025238.4 , NM_025238.3
Accession Version	NM_025238.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	BTB/POZ domain-containing protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI553790.1, BC028097.1 and AF257241.1. On Feb 15, 2005 this sequence version replaced NM_025238.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AF257241.1, SRR1660807.158178.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATTCA CAGTTAATAG AAGGATCTCT 
ATAGTTGGAT TTGGCTTGTA TGGATCTATT CATGGCCCTA CAGATTATCA AGTGAATATA 
CAGATCATTG AATATGAGAA AAAGCAAACC CTGGGACAGA ATGATACCGG CTTTAGTTGT 
GATGGGACAG CTAACACATT CAGGGTCATG TTCAAGGAAC CCATAGAGAT CCTGCCCAAT 
GTGTGCTACA CAGCATGTGC AACACTCAAA GGTCCAGATT CCCACTATGG CACAAAAGGA 
TTGAAGAAAG TAGTGCATGA GACACCTGCT GCAAGCAAGA CTGTTTTTTT CTTTTTTAGT 
TCCCCTGGCA ATAATAATGG CACTTCAATA GAAGATGGAC AAATTCCAGA AATCATATTT 
TATACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079514.1
CDS	204..1652
Translation	MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRFTVNRRISIVGFGLYGSIHGPTDYQVNIQIIEYEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCYTACATLKGPDSHYGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSIEDGQIPEIIFYT

Target ORF information:

RefSeq Version	NM_025238.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025238.3

ORF Insert Sequence:

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATTCA CAGTTAATAG AAGGATCTCT 
ATAGTTGGAT TTGGCTTGTA TGGATCTATT CATGGCCCTA CAGATTATCA AGTGAATATA 
CAGATCATTG AATATGAGAA AAAGCAAACC CTGGGACAGA ATGATACCGG CTTTAGTTGT 
GATGGGACAG CTAACACATT CAGGGTCATG TTCAAGGAAC CCATAGAGAT CCTGCCCAAT 
GTGTGCTACA CAGCATGTGC AACACTCAAA GGTCCAGATT CCCACTATGG CACAAAAGGA 
TTGAAGAAAG TAGTGCATGA GACACCTGCT GCAAGCAAGA CTGTTTTTTT CTTTTTTAGT 
TCCCCTGGCA ATAATAATGG CACTTCAATA GAAGATGGAC AAATTCCAGA AATCATATTT 
TATACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BTBD1 ( NM_001011885.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001011885.1 Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04020
Clone ID Related Accession (Same CDS sequence)	NM_001011885.2 , NM_001011885.1
Accession Version	NM_001011885.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	BTB/POZ domain-containing protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI553790.1, BC028097.1, BF095127.1 and AF257241.1. On May 31, 2019 this sequence version replaced NM_001011885.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.72861.1, SRR1660805.235889.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATCAT TGAATATGAG AAAAAGCAAA 
CCCTGGGACA GAATGATACC GGCTTTAGTT GTGATGGGAC AGCTAACACA TTCAGGGTCA 
TGTTCAAGGA ACCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011885.1
CDS	102..1259
Translation	MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRSLNMRKSKPWDRMIPALVVMGQLTHSGSCSRNP

Target ORF information:

RefSeq Version	NM_001011885.2
Organism	Homo sapiens(human)
Definition	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011885.2

ORF Insert Sequence:

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATCAT TGAATATGAG AAAAAGCAAA 
CCCTGGGACA GAATGATACC GGCTTTAGTT GTGATGGGAC AGCTAACACA TTCAGGGTCA 
TGTTCAAGGA ACCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BTBD1 ( NM_001011885.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001011885.1 Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 2, mRNA.

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CloneID	OHu04020
Clone ID Related Accession (Same CDS sequence)	NM_001011885.2 , NM_001011885.1
Accession Version	NM_001011885.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	BTB/POZ domain-containing protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI553790.1, BC028097.1, BF095127.1 and AF257241.1. Transcript Variant: This variant (2) lacks an exon in the 3' coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.180965.1, SRR1660809.173295.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATCAT TGAATATGAG AAAAAGCAAA 
CCCTGGGACA GAATGATACC GGCTTTAGTT GTGATGGGAC AGCTAACACA TTCAGGGTCA 
TGTTCAAGGA ACCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011885.1
CDS	204..1361
Translation	MASLGPAAAGEQASGAEAEPGPAGPPPPPSPSSLGPLLPLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFVLAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSIRESRLFGAVVRWAEAECQRQQLPVTFGNKQKVLGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGKECCINRFQQVESRWGYSGTSDRIRSLNMRKSKPWDRMIPALVVMGQLTHSGSCSRNP

Target ORF information:

RefSeq Version	NM_001011885.1
Organism	Homo sapiens(human)
Definition	Homo sapiens BTB domain containing 1 (BTBD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011885.1

ORF Insert Sequence:

ATGGCCTCAC TCGGGCCTGC CGCAGCTGGG GAGCAGGCGT CGGGGGCTGA GGCGGAGCCG 
GGCCCCGCGG GGCCGCCGCC GCCGCCCTCA CCGTCCTCTC TGGGGCCCCT GCTCCCCCTG 
CAGCGGGAAC CTCTCTACAA CTGGCAGGCG ACCAAGGCGT CGCTGAAGGA GCGCTTCGCC 
TTCCTCTTCA ACTCGGAGCT GCTGAGCGAT GTGCGCTTCG TACTGGGCAA GGGTCGCGGC 
GCCGCCGCCG CTGGGGGCCC GCAGCGCATC CCCGCCCACC GCTTCGTGCT GGCGGCCGGC 
AGCGCCGTCT TTGACGCCAT GTTCAACGGC GGCATGGCCA CCACGTCGGC CGAGATCGAG 
CTGCCGGACG TGGAGCCCGC AGCCTTCCTG GCGCTGCTGA GATTTCTATA TTCAGATGAA 
GTTCAAATTG GTCCAGAAAC AGTTATGACC ACTCTTTATA CTGCCAAGAA ATACGCAGTC 
CCAGCCTTGG AAGCACACTG TGTAGAATTT CTCACCAAAC ATCTTAGGGC AGATAATGCC 
TTTATGTTAC TTACTCAGGC TCGATTATTT GATGAACCTC AGCTTGCTAG TCTTTGTCTA 
GATACAATAG ACAAAAGCAC AATGGATGCA ATAAGTGCAG AAGGGTTTAC TGATATTGAT 
ATAGATACAC TCTGTGCAGT TTTAGAGAGA GACACACTCA GTATTCGAGA AAGTCGACTT 
TTTGGAGCTG TTGTACGCTG GGCAGAAGCA GAATGTCAGA GACAACAATT ACCTGTGACT 
TTTGGGAATA AACAAAAAGT TCTAGGAAAA GCACTTTCCT TAATCCGGTT CCCACTGATG 
ACAATTGAGG AATTTGCAGC AGGTCCTGCT CAATCTGGAA TTTTGTCAGA TCGTGAAGTG 
GTAAACCTCT TTCTTCATTT TACTGTCAAC CCTAAACCCC GAGTTGAATA CATTGACCGA 
CCAAGATGCT GTCTCAGGGG AAAGGAATGC TGCATCAATA GATTCCAGCA AGTAGAAAGC 
CGCTGGGGTT ACAGTGGGAC GAGTGATCGA ATCAGATCAT TGAATATGAG AAAAAGCAAA 
CCCTGGGACA GAATGATACC GGCTTTAGTT GTGATGGGAC AGCTAACACA TTCAGGGTCA 
TGTTCAAGGA ACCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions.
PLoS pathogens8(6)e1002761(2012)
Muller M,Jacob Y,Jones L,Weiss A,Brino L,Chantier T,Lotteau V,Favre M,Demeret C

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study.
PloS one6(2)e16853(2011 Feb)
Tsai FJ,Lee YC,Chang JS,Huang LM,Huang FY,Chiu NC,Chen MR,Chi H,Lee YJ,Chang LC,Liu YM,Wang HH,Chen CH,Chen YT,Wu JY

Human TOP1 residues implicated in species specificity of HIV-1 infection are required for interaction with BTBD2, and RNAi of BTBD2 in old world monkey and human cells increases permissiveness to HIV-1 infection.
Virology journal7332(2010 Nov)
Khurana B,Zhuang L,Moitra PK,Stantchev TS,Broder CC,Cutler ML,D'Arpa P

CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592.
European journal of human genetics : EJHG18(10)1107-13(2010 Oct)
Nicolas E,Poitelon Y,Chouery E,Salem N,Levy N,M?garban? A,Delague V

Search for cellular partners of human papillomavirus type 16 E2 protein.
Archives of virology153(5)983-90(2008)
Olejnik-Schmidt AK,Schmidt MT,Kedzia W,Go?dzicka-J?zefiak A

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BTBD1 cDNA ORF clone, Homo sapiens(human)

Gene

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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