PIP4K2A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PIP4K2A
Entrez Gene ID	5305
Full Name	phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
Synonyms	PI5P4KA,PIP5K2A,PIP5KII-alpha,PIP5KIIA,PIPK
General protein information	Preferred Names phosphatidylinositol-5-phosphate 4-kinase type 2 alpha Names phosphatidylinositol 5-phosphate 4-kinase type-2 alpha 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha 1-phosphatidylinositol-4-phosphate kinase 1-phosphatidylinositol-4-phosphate-5-kinase PI(5)P 4-kinase type II alpha PIP4KII-alpha PIP5KIII PIP5KIIalpha PtdIns(4)P-5-kinase B isoform diphosphoinositide kinase 2-alpha phosphatidylinositol 5-phosphate 4-kinase type II alpha phosphatidylinositol-4-phosphate 5-kinase, type II, alpha ptdIns(4)P-5-kinase C isoform ptdIns(5)P-4-kinase isoform 2-alpha type II phosphatidylinositol-4-phosphate 5-kinase 53 K isoform
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p12.2
Summary	Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq, Jul 2008].
Disorder MIM:	603140

mRNA and Protein(s)

mRNA	Protein	Name
NM_005028.4	NP_005019.2	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 1
NM_001330062.1	NP_001316991.1	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 2
XM_006717450.2	XP_006717513.1	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1
XM_017016330.1	XP_016871819.1	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2
XM_017016331.1	XP_016871820.1	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2
NM_005028.5	NP_005019.2	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 1
XM_017016332.1	XP_016871821.1	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X3

Pathways from BioSystems

Homologies

Homo sapiens (human)	PIP4K2A	NP_005019.2
Canis lupus familiaris (dog)	PIP4K2A	XP_850532.1
Danio rerio (zebrafish)	pip4k2aa	NP_001122174.1
	PIP4K2A	XP_001099389.2
Mus musculus (house mouse)	Pip4k2a	NP_032871.3
Rattus norvegicus (Norway rat)	Pip4k2a	NP_446378.1
Xenopus tropicalis (tropical clawed frog)	pip4k2b	NP_001123723.1
Pan troglodytes (chimpanzee)	PIP4K2A	XP_001145662.2
Bos taurus (cattle)	PIP4K2A	NP_001179698.1
Gallus gallus (chicken)	PIP4K2A	NP_001026142.1

Gene Ontology
Bibliography

Related articles in PubMed

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.
Hu A, Zhao XT, Tu H, Xiao T, Fu T, Wang Y, Liu Y, Shi XJ, Luo J, Song BL
Journal of lipid research(2018 Jan)

ARID5B, CEBPE and PIP4K2A Germline Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in Mexican Patients: A?MIGICCL Study.
Bekker-M?ndez VC, N??ez-Enr?quez JC, Torres Escalante JL, Alvarez-Olmos E, Gonz?lez-Montalvoc PM, Jim?nez-Hern?ndez E, Sans?n AM, Leal YA, Ramos-Cervantes MT, Guerra-Castillo FX, Ortiz-Maganda MP, Flores-Lujano J, P?rez-Saldivar ML, Velazquez-Avi?a MM, Bolea-Murga V, Torres-Nava JR, Amador-Sanchez R, Solis-Labastida KA, R?mirez-Bello J, Fragoso JM, Mej?a-Arangur? JM,
Archives of medical research47(8)623-628(2016 Nov)

Association Between PIP4K2A Polymorphisms and Acute Lymphoblastic Leukemia Susceptibility.
Liao F, Yin D, Zhang Y, Hou Q, Zheng Z, Yang L, Shu Y, Xu H, Li Y
Medicine95(18)e3542(2016 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the rs7088318 (PIP4K2A) and rs2239633 (CEBPE) polymorphisms were not associated with ALL risk.
Title: ARID5B, CEBPE and PIP4K2A Germline Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in Mexican Patients: A?MIGICCL Study.

meta-analysis of association of SNPs rs7088318 and rs4748793 and acute lymphoblastic leukemia susceptibility
Title: Association Between PIP4K2A Polymorphisms and Acute Lymphoblastic Leukemia Susceptibility.

PIP5K2A is possibly involved in a mechanism protecting against tardive dyskinesia-inducing neurotoxicity.
Title: Association study indicates a protective role of phosphatidylinositol-4-phosphate-5-kinase against tardive dyskinesia.

We also showed that PIPKIIalpha silencing can induce alpha and gamma globin expression and decrease cell proliferation in K562 cells.
Title: PIPKII? is widely expressed in hematopoietic-derived cells and may play a role in the expression of alpha- and gamma-globins in K562 cells.

The diplotype ATTGCT/ATTGCT of the PIP4K2A gene confers approximately three-times higher incomplete responsiveness towards antipsychotics in severely ill patients.
Title: Genetic variations of PIP4K2A confer vulnerability to poor antipsychotic response in severely ill schizophrenia patients.

The following PIP4K2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PIP4K2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13335	NM_005028.5 Latest version!	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu59709	NM_001330062.1 Latest version!	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu59709	XM_017016330.1 Latest version!	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu59709	XM_017016331.1 Latest version!	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OHu43763	XM_006717450.2 Latest version!	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu91468	XM_017016332.1 Latest version!	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu13335	NM_005028.4	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PIP4K2A ( NM_005028.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005019.2 Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13335
Clone ID Related Accession (Same CDS sequence)	NM_005028.4 , NM_005028.5
Accession Version	NM_005028.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB504104.1, BC018034.1 and AL513128.11. On Aug 24, 2007 this sequence version replaced NM_005028.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC018034.1, SRR1163655.444891.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGACCC CCGGCAACCT AGGGTCCTCT GTCCTGGCGA GCAAGACCAA GACCAAGAAG 
AAGCACTTCG TAGCGCAGAA AGTGAAGCTG TTTCGGGCCA GCGACCCGCT GCTCAGCGTC 
CTCATGTGGG GGGTAAACCA CTCGATCAAT GAACTGAGCC ATGTTCAAAT CCCTGTTATG 
TTGATGCCAG ATGACTTCAA AGCCTATTCA AAAATAAAGG TGGACAATCA CCTTTTTAAC 
AAAGAAAACA TGCCGAGCCA TTTCAAGTTT AAGGAATACT GCCCGATGGT CTTCCGTAAC 
CTGCGGGAGA GGTTTGGAAT TGATGATCAA GATTTCCAGA ATTCCCTGAC CAGGAGCGCA 
CCCCTCCCCA ACGACTCCCA GGCCCGCAGT GGAGCTCGTT TTCACACTTC CTACGACAAA 
AGATACATCA TCAAGACTAT TACCAGTGAA GACGTGGCCG AAATGCACAA CATCCTGAAG 
AAATACCACC AGTACATAGT GGAATGTCAT GGGATCACCC TTCTTCCCCA GTTCTTGGGC 
ATGTACCGGC TTAATGTTGA TGGAGTTGAA ATATATGTGA TAGTTACAAG AAATGTATTC 
AGCCACCGTT TGTCTGTGTA TAGGAAATAC GACTTAAAGG GCTCTACAGT GGCTAGAGAA 
GCTAGTGACA AAGAAAAGGC CAAAGAACTG CCAACTCTGA AAGATAATGA TTTCATTAAT 
GAGGGCCAAA AGATTTATAT TGATGACAAC AACAAGAAGG TCTTCCTGGA AAAACTAAAA 
AAGGATGTTG AGTTTCTGGC CCAGCTGAAG CTCATGGACT ACAGTCTGCT GGTGGGAATT 
CATGATGTGG AGAGAGCCGA ACAGGAGGAA GTGGAGTGTG AGGAGAACGA TGGGGAGGAG 
GAGGGCGAGA GCGATGGCAC CCACCCGGTG GGAACCCCCC CAGATAGCCC CGGGAATACA 
CTGAACAGCT CACCACCCCT GGCTCCCGGG GAGTTCGATC CGAACATCGA CGTCTATGGA 
ATTAAGTGCC ATGAAAACTC GCCTAGGAAG GAGGTGTACT TCATGGCAAT TATTGACATC 
CTTACTCATT ATGATGCAAA AAAGAAAGCT GCCCATGCTG CAAAAACTGT TAAACATGGC 
GCTGGCGCGG AGATCTCCAC CGTGAACCCA GAACAGTATT CAAAGCGCTT TTTGGACTTT 
ATTGGCCACA TCTTGACGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005019.2
CDS	249..1469
Translation	MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT

Target ORF information:

RefSeq Version	NM_005028.4
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005028.4

ORF Insert Sequence:

ATGGCGACCC CCGGCAACCT AGGGTCCTCT GTCCTGGCGA GCAAGACCAA GACCAAGAAG 
AAGCACTTCG TAGCGCAGAA AGTGAAGCTG TTTCGGGCCA GCGACCCGCT GCTCAGCGTC 
CTCATGTGGG GGGTAAACCA CTCGATCAAT GAACTGAGCC ATGTTCAAAT CCCTGTTATG 
TTGATGCCAG ATGACTTCAA AGCCTATTCA AAAATAAAGG TGGACAATCA CCTTTTTAAC 
AAAGAAAACA TGCCGAGCCA TTTCAAGTTT AAGGAATACT GCCCGATGGT CTTCCGTAAC 
CTGCGGGAGA GGTTTGGAAT TGATGATCAA GATTTCCAGA ATTCCCTGAC CAGGAGCGCA 
CCCCTCCCCA ACGACTCCCA GGCCCGCAGT GGAGCTCGTT TTCACACTTC CTACGACAAA 
AGATACATCA TCAAGACTAT TACCAGTGAA GACGTGGCCG AAATGCACAA CATCCTGAAG 
AAATACCACC AGTACATAGT GGAATGTCAT GGGATCACCC TTCTTCCCCA GTTCTTGGGC 
ATGTACCGGC TTAATGTTGA TGGAGTTGAA ATATATGTGA TAGTTACAAG AAATGTATTC 
AGCCACCGTT TGTCTGTGTA TAGGAAATAC GACTTAAAGG GCTCTACAGT GGCTAGAGAA 
GCTAGTGACA AAGAAAAGGC CAAAGAACTG CCAACTCTGA AAGATAATGA TTTCATTAAT 
GAGGGCCAAA AGATTTATAT TGATGACAAC AACAAGAAGG TCTTCCTGGA AAAACTAAAA 
AAGGATGTTG AGTTTCTGGC CCAGCTGAAG CTCATGGACT ACAGTCTGCT GGTGGGAATT 
CATGATGTGG AGAGAGCCGA ACAGGAGGAA GTGGAGTGTG AGGAGAACGA TGGGGAGGAG 
GAGGGCGAGA GCGATGGCAC CCACCCGGTG GGAACCCCCC CAGATAGCCC CGGGAATACA 
CTGAACAGCT CACCACCCCT GGCTCCCGGG GAGTTCGATC CGAACATCGA CGTCTATGGA 
ATTAAGTGCC ATGAAAACTC GCCTAGGAAG GAGGTGTACT TCATGGCAAT TATTGACATC 
CTTACTCATT ATGATGCAAA AAAGAAAGCT GCCCATGCTG CAAAAACTGT TAAACATGGC 
GCTGGCGCGG AGATCTCCAC CGTGAACCCA GAACAGTATT CAAAGCGCTT TTTGGACTTT 
ATTGGCCACA TCTTGACGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIP4K2A ( NM_005028.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005019.2 Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13335
Clone ID Related Accession (Same CDS sequence)	NM_005028.4 , NM_005028.5
Accession Version	NM_005028.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL390318.20, DB504104.1, BC018034.1 and AL513128.11. On Nov 23, 2018 this sequence version replaced NM_005028.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC018034.1, SRR1163655.444891.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000376573.9/ ENSP00000365757.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGACCC CCGGCAACCT AGGGTCCTCT GTCCTGGCGA GCAAGACCAA GACCAAGAAG 
AAGCACTTCG TAGCGCAGAA AGTGAAGCTG TTTCGGGCCA GCGACCCGCT GCTCAGCGTC 
CTCATGTGGG GGGTAAACCA CTCGATCAAT GAACTGAGCC ATGTTCAAAT CCCTGTTATG 
TTGATGCCAG ATGACTTCAA AGCCTATTCA AAAATAAAGG TGGACAATCA CCTTTTTAAC 
AAAGAAAACA TGCCGAGCCA TTTCAAGTTT AAGGAATACT GCCCGATGGT CTTCCGTAAC 
CTGCGGGAGA GGTTTGGAAT TGATGATCAA GATTTCCAGA ATTCCCTGAC CAGGAGCGCA 
CCCCTCCCCA ACGACTCCCA GGCCCGCAGT GGAGCTCGTT TTCACACTTC CTACGACAAA 
AGATACATCA TCAAGACTAT TACCAGTGAA GACGTGGCCG AAATGCACAA CATCCTGAAG 
AAATACCACC AGTACATAGT GGAATGTCAT GGGATCACCC TTCTTCCCCA GTTCTTGGGC 
ATGTACCGGC TTAATGTTGA TGGAGTTGAA ATATATGTGA TAGTTACAAG AAATGTATTC 
AGCCACCGTT TGTCTGTGTA TAGGAAATAC GACTTAAAGG GCTCTACAGT GGCTAGAGAA 
GCTAGTGACA AAGAAAAGGC CAAAGAACTG CCAACTCTGA AAGATAATGA TTTCATTAAT 
GAGGGCCAAA AGATTTATAT TGATGACAAC AACAAGAAGG TCTTCCTGGA AAAACTAAAA 
AAGGATGTTG AGTTTCTGGC CCAGCTGAAG CTCATGGACT ACAGTCTGCT GGTGGGAATT 
CATGATGTGG AGAGAGCCGA ACAGGAGGAA GTGGAGTGTG AGGAGAACGA TGGGGAGGAG 
GAGGGCGAGA GCGATGGCAC CCACCCGGTG GGAACCCCCC CAGATAGCCC CGGGAATACA 
CTGAACAGCT CACCACCCCT GGCTCCCGGG GAGTTCGATC CGAACATCGA CGTCTATGGA 
ATTAAGTGCC ATGAAAACTC GCCTAGGAAG GAGGTGTACT TCATGGCAAT TATTGACATC 
CTTACTCATT ATGATGCAAA AAAGAAAGCT GCCCATGCTG CAAAAACTGT TAAACATGGC 
GCTGGCGCGG AGATCTCCAC CGTGAACCCA GAACAGTATT CAAAGCGCTT TTTGGACTTT 
ATTGGCCACA TCTTGACGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005019.2
CDS	253..1473
Translation	MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT

Target ORF information:

RefSeq Version	NM_005028.5
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005028.5

ORF Insert Sequence:

ATGGCGACCC CCGGCAACCT AGGGTCCTCT GTCCTGGCGA GCAAGACCAA GACCAAGAAG 
AAGCACTTCG TAGCGCAGAA AGTGAAGCTG TTTCGGGCCA GCGACCCGCT GCTCAGCGTC 
CTCATGTGGG GGGTAAACCA CTCGATCAAT GAACTGAGCC ATGTTCAAAT CCCTGTTATG 
TTGATGCCAG ATGACTTCAA AGCCTATTCA AAAATAAAGG TGGACAATCA CCTTTTTAAC 
AAAGAAAACA TGCCGAGCCA TTTCAAGTTT AAGGAATACT GCCCGATGGT CTTCCGTAAC 
CTGCGGGAGA GGTTTGGAAT TGATGATCAA GATTTCCAGA ATTCCCTGAC CAGGAGCGCA 
CCCCTCCCCA ACGACTCCCA GGCCCGCAGT GGAGCTCGTT TTCACACTTC CTACGACAAA 
AGATACATCA TCAAGACTAT TACCAGTGAA GACGTGGCCG AAATGCACAA CATCCTGAAG 
AAATACCACC AGTACATAGT GGAATGTCAT GGGATCACCC TTCTTCCCCA GTTCTTGGGC 
ATGTACCGGC TTAATGTTGA TGGAGTTGAA ATATATGTGA TAGTTACAAG AAATGTATTC 
AGCCACCGTT TGTCTGTGTA TAGGAAATAC GACTTAAAGG GCTCTACAGT GGCTAGAGAA 
GCTAGTGACA AAGAAAAGGC CAAAGAACTG CCAACTCTGA AAGATAATGA TTTCATTAAT 
GAGGGCCAAA AGATTTATAT TGATGACAAC AACAAGAAGG TCTTCCTGGA AAAACTAAAA 
AAGGATGTTG AGTTTCTGGC CCAGCTGAAG CTCATGGACT ACAGTCTGCT GGTGGGAATT 
CATGATGTGG AGAGAGCCGA ACAGGAGGAA GTGGAGTGTG AGGAGAACGA TGGGGAGGAG 
GAGGGCGAGA GCGATGGCAC CCACCCGGTG GGAACCCCCC CAGATAGCCC CGGGAATACA 
CTGAACAGCT CACCACCCCT GGCTCCCGGG GAGTTCGATC CGAACATCGA CGTCTATGGA 
ATTAAGTGCC ATGAAAACTC GCCTAGGAAG GAGGTGTACT TCATGGCAAT TATTGACATC 
CTTACTCATT ATGATGCAAA AAAGAAAGCT GCCCATGCTG CAAAAACTGT TAAACATGGC 
GCTGGCGCGG AGATCTCCAC CGTGAACCCA GAACAGTATT CAAAGCGCTT TTTGGACTTT 
ATTGGCCACA TCTTGACGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIP4K2A ( NM_001330062.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001316991.1 Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu59709
Clone ID Related Accession (Same CDS sequence)	NM_001330062.1 , XM_017016330.1 , XM_017016331.1
Accession Version	NM_001330062.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Homo sapiens(human)
Product	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK294817.1, AL513128.11 and HY318006.1. On Aug 16, 2016 this sequence version replaced XM_011519496.1. Transcript Variant: This variant (2) uses an alternate 5'-terminal exon resulting in a different 5' UTR and use of a downstream AUG compared to variant 1. It encodes isoform 2, which has a shorter N-terminus than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294817.1, SRR1660807.291399.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGAATTCCCT GACCAGGAGC 
GCACCCCTCC CCAACGACTC CCAGGCCCGC AGTGGAGCTC GTTTTCACAC TTCCTACGAC 
AAAAGATACA TCATCAAGAC TATTACCAGT GAAGACGTGG CCGAAATGCA CAACATCCTG 
AAGAAATACC ACCAGTACAT AGTGGAATGT CATGGGATCA CCCTTCTTCC CCAGTTCTTG 
GGCATGTACC GGCTTAATGT TGATGGAGTT GAAATATATG TGATAGTTAC AAGAAATGTA 
TTCAGCCACC GTTTGTCTGT GTATAGGAAA TACGACTTAA AGGGCTCTAC AGTGGCTAGA 
GAAGCTAGTG ACAAAGAAAA GGCCAAAGAA CTGCCAACTC TGAAAGATAA TGATTTCATT 
AATGAGGGCC AAAAGATTTA TATTGATGAC AACAACAAGA AGGTCTTCCT GGAAAAACTA 
AAAAAGGATG TTGAGTTTCT GGCCCAGCTG AAGCTCATGG ACTACAGTCT GCTGGTGGGA 
ATTCATGATG TGGAGAGAGC CGAACAGGAG GAAGTGGAGT GTGAGGAGAA CGATGGGGAG 
GAGGAGGGCG AGAGCGATGG CACCCACCCG GTGGGAACCC CCCCAGATAG CCCCGGGAAT 
ACACTGAACA GCTCACCACC CCTGGCTCCC GGGGAGTTCG ATCCGAACAT CGACGTCTAT 
GGAATTAAGT GCCATGAAAA CTCGCCTAGG AAGGAGGTGT ACTTCATGGC AATTATTGAC 
ATCCTTACTC ATTATGATGC AAAAAAGAAA GCTGCCCATG CTGCAAAAAC TGTTAAACAT 
GGCGCTGGCG CGGAGATCTC CACCGTGAAC CCAGAACAGT ATTCAAAGCG CTTTTTGGAC 
TTTATTGGCC ACATCTTGAC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001316991.1
CDS	207..1250
Translation	MLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT

Target ORF information:

RefSeq Version	NM_001330062.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330062.1

ORF Insert Sequence:

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGAATTCCCT GACCAGGAGC 
GCACCCCTCC CCAACGACTC CCAGGCCCGC AGTGGAGCTC GTTTTCACAC TTCCTACGAC 
AAAAGATACA TCATCAAGAC TATTACCAGT GAAGACGTGG CCGAAATGCA CAACATCCTG 
AAGAAATACC ACCAGTACAT AGTGGAATGT CATGGGATCA CCCTTCTTCC CCAGTTCTTG 
GGCATGTACC GGCTTAATGT TGATGGAGTT GAAATATATG TGATAGTTAC AAGAAATGTA 
TTCAGCCACC GTTTGTCTGT GTATAGGAAA TACGACTTAA AGGGCTCTAC AGTGGCTAGA 
GAAGCTAGTG ACAAAGAAAA GGCCAAAGAA CTGCCAACTC TGAAAGATAA TGATTTCATT 
AATGAGGGCC AAAAGATTTA TATTGATGAC AACAACAAGA AGGTCTTCCT GGAAAAACTA 
AAAAAGGATG TTGAGTTTCT GGCCCAGCTG AAGCTCATGG ACTACAGTCT GCTGGTGGGA 
ATTCATGATG TGGAGAGAGC CGAACAGGAG GAAGTGGAGT GTGAGGAGAA CGATGGGGAG 
GAGGAGGGCG AGAGCGATGG CACCCACCCG GTGGGAACCC CCCCAGATAG CCCCGGGAAT 
ACACTGAACA GCTCACCACC CCTGGCTCCC GGGGAGTTCG ATCCGAACAT CGACGTCTAT 
GGAATTAAGT GCCATGAAAA CTCGCCTAGG AAGGAGGTGT ACTTCATGGC AATTATTGAC 
ATCCTTACTC ATTATGATGC AAAAAAGAAA GCTGCCCATG CTGCAAAAAC TGTTAAACAT 
GGCGCTGGCG CGGAGATCTC CACCGTGAAC CCAGAACAGT ATTCAAAGCG CTTTTTGGAC 
TTTATTGGCC ACATCTTGAC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIP4K2A ( XM_017016330.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016871819.1 Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu59709
Clone ID Related Accession (Same CDS sequence)	NM_001330062.1 , XM_017016330.1 , XM_017016331.1
Accession Version	XM_017016330.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGAATTCCCT GACCAGGAGC 
GCACCCCTCC CCAACGACTC CCAGGCCCGC AGTGGAGCTC GTTTTCACAC TTCCTACGAC 
AAAAGATACA TCATCAAGAC TATTACCAGT GAAGACGTGG CCGAAATGCA CAACATCCTG 
AAGAAATACC ACCAGTACAT AGTGGAATGT CATGGGATCA CCCTTCTTCC CCAGTTCTTG 
GGCATGTACC GGCTTAATGT TGATGGAGTT GAAATATATG TGATAGTTAC AAGAAATGTA 
TTCAGCCACC GTTTGTCTGT GTATAGGAAA TACGACTTAA AGGGCTCTAC AGTGGCTAGA 
GAAGCTAGTG ACAAAGAAAA GGCCAAAGAA CTGCCAACTC TGAAAGATAA TGATTTCATT 
AATGAGGGCC AAAAGATTTA TATTGATGAC AACAACAAGA AGGTCTTCCT GGAAAAACTA 
AAAAAGGATG TTGAGTTTCT GGCCCAGCTG AAGCTCATGG ACTACAGTCT GCTGGTGGGA 
ATTCATGATG TGGAGAGAGC CGAACAGGAG GAAGTGGAGT GTGAGGAGAA CGATGGGGAG 
GAGGAGGGCG AGAGCGATGG CACCCACCCG GTGGGAACCC CCCCAGATAG CCCCGGGAAT 
ACACTGAACA GCTCACCACC CCTGGCTCCC GGGGAGTTCG ATCCGAACAT CGACGTCTAT 
GGAATTAAGT GCCATGAAAA CTCGCCTAGG AAGGAGGTGT ACTTCATGGC AATTATTGAC 
ATCCTTACTC ATTATGATGC AAAAAAGAAA GCTGCCCATG CTGCAAAAAC TGTTAAACAT 
GGCGCTGGCG CGGAGATCTC CACCGTGAAC CCAGAACAGT ATTCAAAGCG CTTTTTGGAC 
TTTATTGGCC ACATCTTGAC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016871819.1
CDS	260..1303
Translation	MLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT

Target ORF information:

RefSeq Version	XM_017016330.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016330.1

ORF Insert Sequence:

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGAATTCCCT GACCAGGAGC 
GCACCCCTCC CCAACGACTC CCAGGCCCGC AGTGGAGCTC GTTTTCACAC TTCCTACGAC 
AAAAGATACA TCATCAAGAC TATTACCAGT GAAGACGTGG CCGAAATGCA CAACATCCTG 
AAGAAATACC ACCAGTACAT AGTGGAATGT CATGGGATCA CCCTTCTTCC CCAGTTCTTG 
GGCATGTACC GGCTTAATGT TGATGGAGTT GAAATATATG TGATAGTTAC AAGAAATGTA 
TTCAGCCACC GTTTGTCTGT GTATAGGAAA TACGACTTAA AGGGCTCTAC AGTGGCTAGA 
GAAGCTAGTG ACAAAGAAAA GGCCAAAGAA CTGCCAACTC TGAAAGATAA TGATTTCATT 
AATGAGGGCC AAAAGATTTA TATTGATGAC AACAACAAGA AGGTCTTCCT GGAAAAACTA 
AAAAAGGATG TTGAGTTTCT GGCCCAGCTG AAGCTCATGG ACTACAGTCT GCTGGTGGGA 
ATTCATGATG TGGAGAGAGC CGAACAGGAG GAAGTGGAGT GTGAGGAGAA CGATGGGGAG 
GAGGAGGGCG AGAGCGATGG CACCCACCCG GTGGGAACCC CCCCAGATAG CCCCGGGAAT 
ACACTGAACA GCTCACCACC CCTGGCTCCC GGGGAGTTCG ATCCGAACAT CGACGTCTAT 
GGAATTAAGT GCCATGAAAA CTCGCCTAGG AAGGAGGTGT ACTTCATGGC AATTATTGAC 
ATCCTTACTC ATTATGATGC AAAAAAGAAA GCTGCCCATG CTGCAAAAAC TGTTAAACAT 
GGCGCTGGCG CGGAGATCTC CACCGTGAAC CCAGAACAGT ATTCAAAGCG CTTTTTGGAC 
TTTATTGGCC ACATCTTGAC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIP4K2A ( XM_017016331.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016871820.1 Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu59709
Clone ID Related Accession (Same CDS sequence)	NM_001330062.1 , XM_017016330.1 , XM_017016331.1
Accession Version	XM_017016331.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGAATTCCCT GACCAGGAGC 
GCACCCCTCC CCAACGACTC CCAGGCCCGC AGTGGAGCTC GTTTTCACAC TTCCTACGAC 
AAAAGATACA TCATCAAGAC TATTACCAGT GAAGACGTGG CCGAAATGCA CAACATCCTG 
AAGAAATACC ACCAGTACAT AGTGGAATGT CATGGGATCA CCCTTCTTCC CCAGTTCTTG 
GGCATGTACC GGCTTAATGT TGATGGAGTT GAAATATATG TGATAGTTAC AAGAAATGTA 
TTCAGCCACC GTTTGTCTGT GTATAGGAAA TACGACTTAA AGGGCTCTAC AGTGGCTAGA 
GAAGCTAGTG ACAAAGAAAA GGCCAAAGAA CTGCCAACTC TGAAAGATAA TGATTTCATT 
AATGAGGGCC AAAAGATTTA TATTGATGAC AACAACAAGA AGGTCTTCCT GGAAAAACTA 
AAAAAGGATG TTGAGTTTCT GGCCCAGCTG AAGCTCATGG ACTACAGTCT GCTGGTGGGA 
ATTCATGATG TGGAGAGAGC CGAACAGGAG GAAGTGGAGT GTGAGGAGAA CGATGGGGAG 
GAGGAGGGCG AGAGCGATGG CACCCACCCG GTGGGAACCC CCCCAGATAG CCCCGGGAAT 
ACACTGAACA GCTCACCACC CCTGGCTCCC GGGGAGTTCG ATCCGAACAT CGACGTCTAT 
GGAATTAAGT GCCATGAAAA CTCGCCTAGG AAGGAGGTGT ACTTCATGGC AATTATTGAC 
ATCCTTACTC ATTATGATGC AAAAAAGAAA GCTGCCCATG CTGCAAAAAC TGTTAAACAT 
GGCGCTGGCG CGGAGATCTC CACCGTGAAC CCAGAACAGT ATTCAAAGCG CTTTTTGGAC 
TTTATTGGCC ACATCTTGAC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016871820.1
CDS	355..1398
Translation	MLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT

Target ORF information:

RefSeq Version	XM_017016331.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016331.1

ORF Insert Sequence:

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGAATTCCCT GACCAGGAGC 
GCACCCCTCC CCAACGACTC CCAGGCCCGC AGTGGAGCTC GTTTTCACAC TTCCTACGAC 
AAAAGATACA TCATCAAGAC TATTACCAGT GAAGACGTGG CCGAAATGCA CAACATCCTG 
AAGAAATACC ACCAGTACAT AGTGGAATGT CATGGGATCA CCCTTCTTCC CCAGTTCTTG 
GGCATGTACC GGCTTAATGT TGATGGAGTT GAAATATATG TGATAGTTAC AAGAAATGTA 
TTCAGCCACC GTTTGTCTGT GTATAGGAAA TACGACTTAA AGGGCTCTAC AGTGGCTAGA 
GAAGCTAGTG ACAAAGAAAA GGCCAAAGAA CTGCCAACTC TGAAAGATAA TGATTTCATT 
AATGAGGGCC AAAAGATTTA TATTGATGAC AACAACAAGA AGGTCTTCCT GGAAAAACTA 
AAAAAGGATG TTGAGTTTCT GGCCCAGCTG AAGCTCATGG ACTACAGTCT GCTGGTGGGA 
ATTCATGATG TGGAGAGAGC CGAACAGGAG GAAGTGGAGT GTGAGGAGAA CGATGGGGAG 
GAGGAGGGCG AGAGCGATGG CACCCACCCG GTGGGAACCC CCCCAGATAG CCCCGGGAAT 
ACACTGAACA GCTCACCACC CCTGGCTCCC GGGGAGTTCG ATCCGAACAT CGACGTCTAT 
GGAATTAAGT GCCATGAAAA CTCGCCTAGG AAGGAGGTGT ACTTCATGGC AATTATTGAC 
ATCCTTACTC ATTATGATGC AAAAAAGAAA GCTGCCCATG CTGCAAAAAC TGTTAAACAT 
GGCGCTGGCG CGGAGATCTC CACCGTGAAC CCAGAACAGT ATTCAAAGCG CTTTTTGGAC 
TTTATTGGCC ACATCTTGAC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIP4K2A ( XM_006717450.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006717513.1 Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu43763
Clone ID Related Accession (Same CDS sequence)	XM_006717450.2
Accession Version	XM_006717450.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1068bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006717450.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACCC CCGGCAACCT AGGGTCCTCT GTCCTGGCGA GCAAGACCAA GACCAAGAAG 
AAGCACTTCG TAGCGCAGAA AGTGAAGCTG TTTCGGGCCA GCGACCCGCT GCTCAGCGTC 
CTCATGTGGG GGGTAAACCA CTCGATCAAT GAACTGAGCC ATGTTCAAAT CCCTGTTATG 
TTGATGCCAG ATGACTTCAA AGCCTATTCA AAAATAAAGG TGGACAATCA CCTTTTTAAC 
AAAGAAAACA TGCCGAGCCA TTTCAAGTTT AAGGAATACT GCCCGATGGT CTTCCGTAAC 
CTGCGGGAGA GGTTTGGAAT TGATGATCAA GATTTCCAGT ACATAGTGGA ATGTCATGGG 
ATCACCCTTC TTCCCCAGTT CTTGGGCATG TACCGGCTTA ATGTTGATGG AGTTGAAATA 
TATGTGATAG TTACAAGAAA TGTATTCAGC CACCGTTTGT CTGTGTATAG GAAATACGAC 
TTAAAGGGCT CTACAGTGGC TAGAGAAGCT AGTGACAAAG AAAAGGCCAA AGAACTGCCA 
ACTCTGAAAG ATAATGATTT CATTAATGAG GGCCAAAAGA TTTATATTGA TGACAACAAC 
AAGAAGGTCT TCCTGGAAAA ACTAAAAAAG GATGTTGAGT TTCTGGCCCA GCTGAAGCTC 
ATGGACTACA GTCTGCTGGT GGGAATTCAT GATGTGGAGA GAGCCGAACA GGAGGAAGTG 
GAGTGTGAGG AGAACGATGG GGAGGAGGAG GGCGAGAGCG ATGGCACCCA CCCGGTGGGA 
ACCCCCCCAG ATAGCCCCGG GAATACACTG AACAGCTCAC CACCCCTGGC TCCCGGGGAG 
TTCGATCCGA ACATCGACGT CTATGGAATT AAGTGCCATG AAAACTCGCC TAGGAAGGAG 
GTGTACTTCA TGGCAATTAT TGACATCCTT ACTCATTATG ATGCAAAAAA GAAAGCTGCC 
CATGCTGCAA AAACTGTTAA ACATGGCGCT GGCGCGGAGA TCTCCACCGT GAACCCAGAA 
CAGTATTCAA AGCGCTTTTT GGACTTTATT GGCCACATCT TGACGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006717513.1
CDS	244..1311
Translation	MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT

Target ORF information:

RefSeq Version	XM_006717450.2
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006717450.2

ORF Insert Sequence:

ATGGCGACCC CCGGCAACCT AGGGTCCTCT GTCCTGGCGA GCAAGACCAA GACCAAGAAG 
AAGCACTTCG TAGCGCAGAA AGTGAAGCTG TTTCGGGCCA GCGACCCGCT GCTCAGCGTC 
CTCATGTGGG GGGTAAACCA CTCGATCAAT GAACTGAGCC ATGTTCAAAT CCCTGTTATG 
TTGATGCCAG ATGACTTCAA AGCCTATTCA AAAATAAAGG TGGACAATCA CCTTTTTAAC 
AAAGAAAACA TGCCGAGCCA TTTCAAGTTT AAGGAATACT GCCCGATGGT CTTCCGTAAC 
CTGCGGGAGA GGTTTGGAAT TGATGATCAA GATTTCCAGT ACATAGTGGA ATGTCATGGG 
ATCACCCTTC TTCCCCAGTT CTTGGGCATG TACCGGCTTA ATGTTGATGG AGTTGAAATA 
TATGTGATAG TTACAAGAAA TGTATTCAGC CACCGTTTGT CTGTGTATAG GAAATACGAC 
TTAAAGGGCT CTACAGTGGC TAGAGAAGCT AGTGACAAAG AAAAGGCCAA AGAACTGCCA 
ACTCTGAAAG ATAATGATTT CATTAATGAG GGCCAAAAGA TTTATATTGA TGACAACAAC 
AAGAAGGTCT TCCTGGAAAA ACTAAAAAAG GATGTTGAGT TTCTGGCCCA GCTGAAGCTC 
ATGGACTACA GTCTGCTGGT GGGAATTCAT GATGTGGAGA GAGCCGAACA GGAGGAAGTG 
GAGTGTGAGG AGAACGATGG GGAGGAGGAG GGCGAGAGCG ATGGCACCCA CCCGGTGGGA 
ACCCCCCCAG ATAGCCCCGG GAATACACTG AACAGCTCAC CACCCCTGGC TCCCGGGGAG 
TTCGATCCGA ACATCGACGT CTATGGAATT AAGTGCCATG AAAACTCGCC TAGGAAGGAG 
GTGTACTTCA TGGCAATTAT TGACATCCTT ACTCATTATG ATGCAAAAAA GAAAGCTGCC 
CATGCTGCAA AAACTGTTAA ACATGGCGCT GGCGCGGAGA TCTCCACCGT GAACCCAGAA 
CAGTATTCAA AGCGCTTTTT GGACTTTATT GGCCACATCT TGACGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIP4K2A ( XM_017016332.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016871821.1 Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu91468
Clone ID Related Accession (Same CDS sequence)	XM_017016332.1
Accession Version	XM_017016332.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGTACATAGT GGAATGTCAT 
GGGATCACCC TTCTTCCCCA GTTCTTGGGC ATGTACCGGC TTAATGTTGA TGGAGTTGAA 
ATATATGTGA TAGTTACAAG AAATGTATTC AGCCACCGTT TGTCTGTGTA TAGGAAATAC 
GACTTAAAGG GCTCTACAGT GGCTAGAGAA GCTAGTGACA AAGAAAAGGC CAAAGAACTG 
CCAACTCTGA AAGATAATGA TTTCATTAAT GAGGGCCAAA AGATTTATAT TGATGACAAC 
AACAAGAAGG TCTTCCTGGA AAAACTAAAA AAGGATGTTG AGTTTCTGGC CCAGCTGAAG 
CTCATGGACT ACAGTCTGCT GGTGGGAATT CATGATGTGG AGAGAGCCGA ACAGGAGGAA 
GTGGAGTGTG AGGAGAACGA TGGGGAGGAG GAGGGCGAGA GCGATGGCAC CCACCCGGTG 
GGAACCCCCC CAGATAGCCC CGGGAATACA CTGAACAGCT CACCACCCCT GGCTCCCGGG 
GAGTTCGATC CGAACATCGA CGTCTATGGA ATTAAGTGCC ATGAAAACTC GCCTAGGAAG 
GAGGTGTACT TCATGGCAAT TATTGACATC CTTACTCATT ATGATGCAAA AAAGAAAGCT 
GCCCATGCTG CAAAAACTGT TAAACATGGC GCTGGCGCGG AGATCTCCAC CGTGAACCCA 
GAACAGTATT CAAAGCGCTT TTTGGACTTT ATTGGCCACA TCTTGACGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016871821.1
CDS	221..1111
Translation	MLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT

Target ORF information:

RefSeq Version	XM_017016332.1
Organism	Homo sapiens(human)
Definition	Homo sapiens phosphatidylinositol-5-phosphate 4-kinase type 2 alpha (PIP4K2A), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016332.1

ORF Insert Sequence:

ATGTTGATGC CAGATGACTT CAAAGCCTAT TCAAAAATAA AGGTGGACAA TCACCTTTTT 
AACAAAGAAA ACATGCCGAG CCATTTCAAG TTTAAGGAAT ACTGCCCGAT GGTCTTCCGT 
AACCTGCGGG AGAGGTTTGG AATTGATGAT CAAGATTTCC AGTACATAGT GGAATGTCAT 
GGGATCACCC TTCTTCCCCA GTTCTTGGGC ATGTACCGGC TTAATGTTGA TGGAGTTGAA 
ATATATGTGA TAGTTACAAG AAATGTATTC AGCCACCGTT TGTCTGTGTA TAGGAAATAC 
GACTTAAAGG GCTCTACAGT GGCTAGAGAA GCTAGTGACA AAGAAAAGGC CAAAGAACTG 
CCAACTCTGA AAGATAATGA TTTCATTAAT GAGGGCCAAA AGATTTATAT TGATGACAAC 
AACAAGAAGG TCTTCCTGGA AAAACTAAAA AAGGATGTTG AGTTTCTGGC CCAGCTGAAG 
CTCATGGACT ACAGTCTGCT GGTGGGAATT CATGATGTGG AGAGAGCCGA ACAGGAGGAA 
GTGGAGTGTG AGGAGAACGA TGGGGAGGAG GAGGGCGAGA GCGATGGCAC CCACCCGGTG 
GGAACCCCCC CAGATAGCCC CGGGAATACA CTGAACAGCT CACCACCCCT GGCTCCCGGG 
GAGTTCGATC CGAACATCGA CGTCTATGGA ATTAAGTGCC ATGAAAACTC GCCTAGGAAG 
GAGGTGTACT TCATGGCAAT TATTGACATC CTTACTCATT ATGATGCAAA AAAGAAAGCT 
GCCCATGCTG CAAAAACTGT TAAACATGGC GCTGGCGCGG AGATCTCCAC CGTGAACCCA 
GAACAGTATT CAAAGCGCTT TTTGGACTTT ATTGGCCACA TCTTGACGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.
Journal of lipid research(2018 Jan)
Hu A,Zhao XT,Tu H,Xiao T,Fu T,Wang Y,Liu Y,Shi XJ,Luo J,Song BL

ARID5B, CEBPE and PIP4K2A Germline Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in Mexican Patients: A?MIGICCL Study.
Archives of medical research47(8)623-628(2016 Nov)
Bekker-M?ndez VC,N??ez-Enr?quez JC,Torres Escalante JL,Alvarez-Olmos E,Gonz?lez-Montalvoc PM,Jim?nez-Hern?ndez E,Sans?n AM,Leal YA,Ramos-Cervantes MT,Guerra-Castillo FX,Ortiz-Maganda MP,Flores-Lujano J,P?rez-Saldivar ML,Velazquez-Avi?a MM,Bolea-Murga V,Torres-Nava JR,Amador-Sanchez R,Solis-Labastida KA,R?mirez-Bello J,Fragoso JM,Mej?a-Arangur? JM,

Association Between PIP4K2A Polymorphisms and Acute Lymphoblastic Leukemia Susceptibility.
Medicine95(18)e3542(2016 May)
Liao F,Yin D,Zhang Y,Hou Q,Zheng Z,Yang L,Shu Y,Xu H,Li Y

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PIP4K2A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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