PIGR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PIGR
Entrez Gene ID	5284
Full Name	polymeric immunoglobulin receptor
General protein information	Preferred Names polymeric immunoglobulin receptor Names polymeric immunoglobulin receptor hepatocellular carcinoma associated protein TB6 poly-Ig receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1
Summary	This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009].
Disorder MIM:	173880

mRNA and Protein(s)

mRNA	Protein	Name
NM_002644.3	NP_002635.2	polymeric immunoglobulin receptor precursor
XM_011509629.1	XP_011507931.1	polymeric immunoglobulin receptor isoform X1
NM_002644.4	NP_002635.2	polymeric immunoglobulin receptor precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PIGR	XP_537133.3
Bos taurus (cattle)	PIGR	NP_776568.1
Rattus norvegicus (Norway rat)	Pigr	NP_036855.3
Homo sapiens (human)	PIGR	NP_002635.2
Pan troglodytes (chimpanzee)	PIGR	XP_003308758.1
Gallus gallus (chicken)	PIGR	NP_001038109.1
	PIGR	XP_001083307.2
Mus musculus (house mouse)	Pigr	NP_035212.2
Xenopus tropicalis (tropical clawed frog)	LOC100495453	XP_002932180.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma.
Arumugam P, Bhattacharya S, Chin-Aleong J, Capaso M, Kocher HM
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]17(2)295-302(2017 Mar - Apr)

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion.
Iovino F, Engelen-Lee JY, Brouwer M, van de Beek D, van der Ende A, Valls Seron M, Mellroth P, Muschiol S, Bergstrand J, Widengren J, Henriques-Normark B
The Journal of experimental medicine214(6)1619-1630(2017 Jun)

A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic.
Ward-Caviness CK, Neas LM, Blach C, Haynes CS, LaRocque-Abramson K, Grass E, Dowdy ZE, Devlin RB, Diaz-Sanchez D, Cascio WE, Miranda ML, Gregory SG, Shah SH, Kraus WE, Hauser ER
PloS one12(3)e0173880(2017)

Sentinel Lymph Node Genes to Predict Prognosis in Node-Positive Melanoma Patients.
Hao H, Xiao D, Pan J, Qu J, Egger M, Waigel S, Sanders MA, Zacharias W, Rai SN, McMasters KM
Annals of surgical oncology24(1)108-116(2017 Jan)

The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins.
Stadtmueller BM, Huey-Tubman KE, L?pez CJ, Yang Z, Hubbell WL, Bjorkman PJ
eLife5(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

pIgR may be involved in pancreatic ductal adenocarcinoma progression and may be linked stromal activity. Further work on its precise role is mandated in in vivo models, to understand its influence on cancer progression.
Title: Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma.

RrgA, binds both polymeric immunoglobulin receptor (pIgR) and PECAM-1, whereas the choline binding protein PspC binds, but to a lower extent, only pIgR
Title: pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion.

A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic pollution.
Title: A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic.

The polymeric immunoglobulin receptor secretory component structure comprises five immunoglobulin-like domains (D1-D5) arranged as a triangle, with an interface between ligand-binding domains D1 and D5.
Title: The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins.

These results demonstrate that SLPI down-regulates pIgR expression through the NF-kappaB signaling pathway by inhibiting degradation of IkappaBbeta protein.
Title: Secretory leukocyte protease inhibitor inhibits expression of polymeric immunoglobulin receptor via the NF-?B signaling pathway.

The following PIGR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PIGR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19522	NM_002644.4 Latest version!	Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu19522	XM_011509629.1 Latest version!	Homo sapiens polymeric immunoglobulin receptor (PIGR), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu19522	NM_002644.3	Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PIGR ( NM_002644.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002635.2 Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA.

Price & Availability↑

CloneID	OHu19522
Clone ID Related Accession (Same CDS sequence)	NM_002644.3 , XM_011509629.1 , NM_002644.4
Accession Version	NM_002644.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-08
Organism	Homo sapiens(human)
Product	polymeric immunoglobulin receptor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK225471.1 and AF272149.2. This sequence is a reference standard in the RefSeqGene project. On Jun 13, 2009 this sequence version replaced NM_002644.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF272149.2, X73079.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGCTCT TCGTGCTCAC CTGCCTGCTG GCGGTCTTCC CAGCCATCTC CACGAAGAGT 
CCCATATTTG GTCCCGAGGA GGTGAATAGT GTGGAAGGTA ACTCAGTGTC CATCACGTGC 
TACTACCCAC CCACCTCTGT CAACCGGCAC ACCCGGAAGT ACTGGTGCCG GCAGGGAGCT 
AGAGGTGGCT GCATAACCCT CATCTCCTCG GAGGGCTACG TCTCCAGCAA ATATGCAGGC 
AGGGCTAACC TCACCAACTT CCCGGAGAAC GGCACATTTG TGGTGAACAT TGCCCAGCTG 
AGCCAGGATG ACTCCGGGCG CTACAAGTGT GGCCTGGGCA TCAATAGCCG AGGCCTGTCC 
TTTGATGTCA GCCTGGAGGT CAGCCAGGGT CCTGGGCTCC TAAATGACAC TAAAGTCTAC 
ACAGTGGACC TGGGCAGAAC GGTGACCATC AACTGCCCTT TCAAGACTGA GAATGCTCAA 
AAGAGGAAGT CCTTGTACAA GCAGATAGGC CTGTACCCTG TGCTGGTCAT CGACTCCAGT 
GGTTATGTAA ATCCCAACTA TACAGGAAGA ATACGCCTTG ATATTCAGGG TACTGGCCAG 
TTACTGTTCA GCGTTGTCAT CAACCAACTC AGGCTCAGCG ATGCTGGGCA GTATCTCTGC 
CAGGCTGGGG ATGATTCCAA TAGTAATAAG AAGAATGCTG ACCTCCAAGT GCTAAAGCCC 
GAGCCCGAGC TGGTTTATGA AGACCTGAGG GGCTCAGTGA CCTTCCACTG TGCCCTGGGC 
CCTGAGGTGG CAAACGTGGC CAAATTTCTG TGCCGACAGA GCAGTGGGGA AAACTGTGAC 
GTGGTCGTCA ACACCCTGGG GAAGAGGGCC CCAGCCTTTG AGGGCAGGAT CCTGCTCAAC 
CCCCAGGACA AGGATGGCTC ATTCAGTGTG GTGATCACAG GCCTGAGGAA GGAGGATGCA 
GGGCGCTACC TGTGTGGAGC CCATTCGGAT GGTCAGCTGC AGGAAGGCTC GCCTATCCAG 
GCCTGGCAAC TCTTCGTCAA TGAGGAGTCC ACGATTCCCC GCAGCCCCAC TGTGGTGAAG 
GGGGTGGCAG GAGGCTCTGT GGCCGTGCTC TGCCCCTACA ACCGTAAGGA AAGCAAAAGC 
ATCAAGTACT GGTGTCTCTG GGAAGGGGCC CAGAATGGCC GCTGCCCCCT GCTGGTGGAC 
AGCGAGGGGT GGGTTAAGGC CCAGTACGAG GGCCGCCTCT CCCTGCTGGA GGAGCCAGGC 
AACGGCACCT TCACTGTCAT CCTCAACCAG CTCACCAGCC GGGACGCCGG CTTCTACTGG 
TGTCTGACCA ACGGCGATAC TCTCTGGAGG ACCACCGTGG AGATCAAGAT TATCGAAGGA 
GAACCAAACC TCAAGGTACC AGGGAATGTC ACGGCTGTGC TGGGAGAGAC TCTCAAGGTC 
CCCTGTCACT TTCCATGCAA ATTCTCCTCG TACGAGAAAT ACTGGTGCAA GTGGAATAAC 
ACGGGCTGCC AGGCCCTGCC CAGCCAAGAC GAAGGCCCCA GCAAGGCCTT CGTGAACTGT 
GACGAGAACA GCCGGCTTGT CTCCCTGACC CTGAACCTGG TGACCAGGGC TGATGAGGGC 
TGGTACTGGT GTGGAGTGAA GCAGGGCCAC TTCTATGGAG AGACTGCAGC CGTCTATGTG 
GCAGTTGAAG AGAGGAAGGC AGCGGGGTCC CGCGATGTCA GCCTAGCGAA GGCAGACGCT 
GCTCCTGATG AGAAGGTGCT AGACTCTGGT TTTCGGGAGA TTGAGAACAA AGCCATTCAG 
GATCCCAGGC TTTTTGCAGA GGAAAAGGCG GTGGCAGATA CAAGAGATCA AGCCGATGGG 
AGCAGAGCAT CTGTGGATTC CGGCAGCTCT GAGGAACAAG GTGGAAGCTC CAGAGCGCTG 
GTCTCCACCC TGGTGCCCCT GGGCCTGGTG CTGGCAGTGG GAGCCGTGGC TGTGGGGGTG 
GCCAGAGCCC GGCACAGGAA GAACGTCGAC CGAGTTTCAA TCAGAAGCTA CAGGACAGAC 
ATTAGCATGT CAGACTTCGA GAACTCCAGG GAATTTGGAG CCAATGACAA CATGGGAGCC 
TCTTCGATCA CTCAGGAGAC ATCCCTCGGA GGAAAAGAAG AGTTTGTTGC CACCACTGAG 
AGCACCACAG AGACCAAAGA ACCCAAGAAG GCAAAAAGGT CATCCAAGGA GGAAGCCGAG 
ATGGCCTACA AAGACTTCCT GCTCCAGTCC AGCACCGTGG CCGCCGAGGC CCAGGACGGC 
CCCCAGGAAG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002635.2
CDS	185..2479
Translation	MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPRLFAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGVARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMGASSITQETSLGGKEEFVATTESTTETKEPKKAKRSSKEEAEMAYKDFLLQSSTVAAEAQDGPQEA

Target ORF information:

RefSeq Version	NM_002644.3
Organism	Homo sapiens(human)
Definition	Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002644.3

ORF Insert Sequence:

ATGCTGCTCT TCGTGCTCAC CTGCCTGCTG GCGGTCTTCC CAGCCATCTC CACGAAGAGT 
CCCATATTTG GTCCCGAGGA GGTGAATAGT GTGGAAGGTA ACTCAGTGTC CATCACGTGC 
TACTACCCAC CCACCTCTGT CAACCGGCAC ACCCGGAAGT ACTGGTGCCG GCAGGGAGCT 
AGAGGTGGCT GCATAACCCT CATCTCCTCG GAGGGCTACG TCTCCAGCAA ATATGCAGGC 
AGGGCTAACC TCACCAACTT CCCGGAGAAC GGCACATTTG TGGTGAACAT TGCCCAGCTG 
AGCCAGGATG ACTCCGGGCG CTACAAGTGT GGCCTGGGCA TCAATAGCCG AGGCCTGTCC 
TTTGATGTCA GCCTGGAGGT CAGCCAGGGT CCTGGGCTCC TAAATGACAC TAAAGTCTAC 
ACAGTGGACC TGGGCAGAAC GGTGACCATC AACTGCCCTT TCAAGACTGA GAATGCTCAA 
AAGAGGAAGT CCTTGTACAA GCAGATAGGC CTGTACCCTG TGCTGGTCAT CGACTCCAGT 
GGTTATGTAA ATCCCAACTA TACAGGAAGA ATACGCCTTG ATATTCAGGG TACTGGCCAG 
TTACTGTTCA GCGTTGTCAT CAACCAACTC AGGCTCAGCG ATGCTGGGCA GTATCTCTGC 
CAGGCTGGGG ATGATTCCAA TAGTAATAAG AAGAATGCTG ACCTCCAAGT GCTAAAGCCC 
GAGCCCGAGC TGGTTTATGA AGACCTGAGG GGCTCAGTGA CCTTCCACTG TGCCCTGGGC 
CCTGAGGTGG CAAACGTGGC CAAATTTCTG TGCCGACAGA GCAGTGGGGA AAACTGTGAC 
GTGGTCGTCA ACACCCTGGG GAAGAGGGCC CCAGCCTTTG AGGGCAGGAT CCTGCTCAAC 
CCCCAGGACA AGGATGGCTC ATTCAGTGTG GTGATCACAG GCCTGAGGAA GGAGGATGCA 
GGGCGCTACC TGTGTGGAGC CCATTCGGAT GGTCAGCTGC AGGAAGGCTC GCCTATCCAG 
GCCTGGCAAC TCTTCGTCAA TGAGGAGTCC ACGATTCCCC GCAGCCCCAC TGTGGTGAAG 
GGGGTGGCAG GAGGCTCTGT GGCCGTGCTC TGCCCCTACA ACCGTAAGGA AAGCAAAAGC 
ATCAAGTACT GGTGTCTCTG GGAAGGGGCC CAGAATGGCC GCTGCCCCCT GCTGGTGGAC 
AGCGAGGGGT GGGTTAAGGC CCAGTACGAG GGCCGCCTCT CCCTGCTGGA GGAGCCAGGC 
AACGGCACCT TCACTGTCAT CCTCAACCAG CTCACCAGCC GGGACGCCGG CTTCTACTGG 
TGTCTGACCA ACGGCGATAC TCTCTGGAGG ACCACCGTGG AGATCAAGAT TATCGAAGGA 
GAACCAAACC TCAAGGTACC AGGGAATGTC ACGGCTGTGC TGGGAGAGAC TCTCAAGGTC 
CCCTGTCACT TTCCATGCAA ATTCTCCTCG TACGAGAAAT ACTGGTGCAA GTGGAATAAC 
ACGGGCTGCC AGGCCCTGCC CAGCCAAGAC GAAGGCCCCA GCAAGGCCTT CGTGAACTGT 
GACGAGAACA GCCGGCTTGT CTCCCTGACC CTGAACCTGG TGACCAGGGC TGATGAGGGC 
TGGTACTGGT GTGGAGTGAA GCAGGGCCAC TTCTATGGAG AGACTGCAGC CGTCTATGTG 
GCAGTTGAAG AGAGGAAGGC AGCGGGGTCC CGCGATGTCA GCCTAGCGAA GGCAGACGCT 
GCTCCTGATG AGAAGGTGCT AGACTCTGGT TTTCGGGAGA TTGAGAACAA AGCCATTCAG 
GATCCCAGGC TTTTTGCAGA GGAAAAGGCG GTGGCAGATA CAAGAGATCA AGCCGATGGG 
AGCAGAGCAT CTGTGGATTC CGGCAGCTCT GAGGAACAAG GTGGAAGCTC CAGAGCGCTG 
GTCTCCACCC TGGTGCCCCT GGGCCTGGTG CTGGCAGTGG GAGCCGTGGC TGTGGGGGTG 
GCCAGAGCCC GGCACAGGAA GAACGTCGAC CGAGTTTCAA TCAGAAGCTA CAGGACAGAC 
ATTAGCATGT CAGACTTCGA GAACTCCAGG GAATTTGGAG CCAATGACAA CATGGGAGCC 
TCTTCGATCA CTCAGGAGAC ATCCCTCGGA GGAAAAGAAG AGTTTGTTGC CACCACTGAG 
AGCACCACAG AGACCAAAGA ACCCAAGAAG GCAAAAAGGT CATCCAAGGA GGAAGCCGAG 
ATGGCCTACA AAGACTTCCT GCTCCAGTCC AGCACCGTGG CCGCCGAGGC CCAGGACGGC 
CCCCAGGAAG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIGR ( NM_002644.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002635.2 Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA.

Price & Availability↑

CloneID	OHu19522
Clone ID Related Accession (Same CDS sequence)	NM_002644.3 , XM_011509629.1 , NM_002644.4
Accession Version	NM_002644.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	polymeric immunoglobulin receptor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK225471.1 and AF272149.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_002644.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF272149.2, X73079.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000356495.5/ ENSP00000348888.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGCTCT TCGTGCTCAC CTGCCTGCTG GCGGTCTTCC CAGCCATCTC CACGAAGAGT 
CCCATATTTG GTCCCGAGGA GGTGAATAGT GTGGAAGGTA ACTCAGTGTC CATCACGTGC 
TACTACCCAC CCACCTCTGT CAACCGGCAC ACCCGGAAGT ACTGGTGCCG GCAGGGAGCT 
AGAGGTGGCT GCATAACCCT CATCTCCTCG GAGGGCTACG TCTCCAGCAA ATATGCAGGC 
AGGGCTAACC TCACCAACTT CCCGGAGAAC GGCACATTTG TGGTGAACAT TGCCCAGCTG 
AGCCAGGATG ACTCCGGGCG CTACAAGTGT GGCCTGGGCA TCAATAGCCG AGGCCTGTCC 
TTTGATGTCA GCCTGGAGGT CAGCCAGGGT CCTGGGCTCC TAAATGACAC TAAAGTCTAC 
ACAGTGGACC TGGGCAGAAC GGTGACCATC AACTGCCCTT TCAAGACTGA GAATGCTCAA 
AAGAGGAAGT CCTTGTACAA GCAGATAGGC CTGTACCCTG TGCTGGTCAT CGACTCCAGT 
GGTTATGTAA ATCCCAACTA TACAGGAAGA ATACGCCTTG ATATTCAGGG TACTGGCCAG 
TTACTGTTCA GCGTTGTCAT CAACCAACTC AGGCTCAGCG ATGCTGGGCA GTATCTCTGC 
CAGGCTGGGG ATGATTCCAA TAGTAATAAG AAGAATGCTG ACCTCCAAGT GCTAAAGCCC 
GAGCCCGAGC TGGTTTATGA AGACCTGAGG GGCTCAGTGA CCTTCCACTG TGCCCTGGGC 
CCTGAGGTGG CAAACGTGGC CAAATTTCTG TGCCGACAGA GCAGTGGGGA AAACTGTGAC 
GTGGTCGTCA ACACCCTGGG GAAGAGGGCC CCAGCCTTTG AGGGCAGGAT CCTGCTCAAC 
CCCCAGGACA AGGATGGCTC ATTCAGTGTG GTGATCACAG GCCTGAGGAA GGAGGATGCA 
GGGCGCTACC TGTGTGGAGC CCATTCGGAT GGTCAGCTGC AGGAAGGCTC GCCTATCCAG 
GCCTGGCAAC TCTTCGTCAA TGAGGAGTCC ACGATTCCCC GCAGCCCCAC TGTGGTGAAG 
GGGGTGGCAG GAGGCTCTGT GGCCGTGCTC TGCCCCTACA ACCGTAAGGA AAGCAAAAGC 
ATCAAGTACT GGTGTCTCTG GGAAGGGGCC CAGAATGGCC GCTGCCCCCT GCTGGTGGAC 
AGCGAGGGGT GGGTTAAGGC CCAGTACGAG GGCCGCCTCT CCCTGCTGGA GGAGCCAGGC 
AACGGCACCT TCACTGTCAT CCTCAACCAG CTCACCAGCC GGGACGCCGG CTTCTACTGG 
TGTCTGACCA ACGGCGATAC TCTCTGGAGG ACCACCGTGG AGATCAAGAT TATCGAAGGA 
GAACCAAACC TCAAGGTACC AGGGAATGTC ACGGCTGTGC TGGGAGAGAC TCTCAAGGTC 
CCCTGTCACT TTCCATGCAA ATTCTCCTCG TACGAGAAAT ACTGGTGCAA GTGGAATAAC 
ACGGGCTGCC AGGCCCTGCC CAGCCAAGAC GAAGGCCCCA GCAAGGCCTT CGTGAACTGT 
GACGAGAACA GCCGGCTTGT CTCCCTGACC CTGAACCTGG TGACCAGGGC TGATGAGGGC 
TGGTACTGGT GTGGAGTGAA GCAGGGCCAC TTCTATGGAG AGACTGCAGC CGTCTATGTG 
GCAGTTGAAG AGAGGAAGGC AGCGGGGTCC CGCGATGTCA GCCTAGCGAA GGCAGACGCT 
GCTCCTGATG AGAAGGTGCT AGACTCTGGT TTTCGGGAGA TTGAGAACAA AGCCATTCAG 
GATCCCAGGC TTTTTGCAGA GGAAAAGGCG GTGGCAGATA CAAGAGATCA AGCCGATGGG 
AGCAGAGCAT CTGTGGATTC CGGCAGCTCT GAGGAACAAG GTGGAAGCTC CAGAGCGCTG 
GTCTCCACCC TGGTGCCCCT GGGCCTGGTG CTGGCAGTGG GAGCCGTGGC TGTGGGGGTG 
GCCAGAGCCC GGCACAGGAA GAACGTCGAC CGAGTTTCAA TCAGAAGCTA CAGGACAGAC 
ATTAGCATGT CAGACTTCGA GAACTCCAGG GAATTTGGAG CCAATGACAA CATGGGAGCC 
TCTTCGATCA CTCAGGAGAC ATCCCTCGGA GGAAAAGAAG AGTTTGTTGC CACCACTGAG 
AGCACCACAG AGACCAAAGA ACCCAAGAAG GCAAAAAGGT CATCCAAGGA GGAAGCCGAG 
ATGGCCTACA AAGACTTCCT GCTCCAGTCC AGCACCGTGG CCGCCGAGGC CCAGGACGGC 
CCCCAGGAAG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002635.2
CDS	185..2479
Translation	MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPRLFAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGVARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMGASSITQETSLGGKEEFVATTESTTETKEPKKAKRSSKEEAEMAYKDFLLQSSTVAAEAQDGPQEA

Target ORF information:

RefSeq Version	NM_002644.4
Organism	Homo sapiens(human)
Definition	Homo sapiens polymeric immunoglobulin receptor (PIGR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002644.4

ORF Insert Sequence:

ATGCTGCTCT TCGTGCTCAC CTGCCTGCTG GCGGTCTTCC CAGCCATCTC CACGAAGAGT 
CCCATATTTG GTCCCGAGGA GGTGAATAGT GTGGAAGGTA ACTCAGTGTC CATCACGTGC 
TACTACCCAC CCACCTCTGT CAACCGGCAC ACCCGGAAGT ACTGGTGCCG GCAGGGAGCT 
AGAGGTGGCT GCATAACCCT CATCTCCTCG GAGGGCTACG TCTCCAGCAA ATATGCAGGC 
AGGGCTAACC TCACCAACTT CCCGGAGAAC GGCACATTTG TGGTGAACAT TGCCCAGCTG 
AGCCAGGATG ACTCCGGGCG CTACAAGTGT GGCCTGGGCA TCAATAGCCG AGGCCTGTCC 
TTTGATGTCA GCCTGGAGGT CAGCCAGGGT CCTGGGCTCC TAAATGACAC TAAAGTCTAC 
ACAGTGGACC TGGGCAGAAC GGTGACCATC AACTGCCCTT TCAAGACTGA GAATGCTCAA 
AAGAGGAAGT CCTTGTACAA GCAGATAGGC CTGTACCCTG TGCTGGTCAT CGACTCCAGT 
GGTTATGTAA ATCCCAACTA TACAGGAAGA ATACGCCTTG ATATTCAGGG TACTGGCCAG 
TTACTGTTCA GCGTTGTCAT CAACCAACTC AGGCTCAGCG ATGCTGGGCA GTATCTCTGC 
CAGGCTGGGG ATGATTCCAA TAGTAATAAG AAGAATGCTG ACCTCCAAGT GCTAAAGCCC 
GAGCCCGAGC TGGTTTATGA AGACCTGAGG GGCTCAGTGA CCTTCCACTG TGCCCTGGGC 
CCTGAGGTGG CAAACGTGGC CAAATTTCTG TGCCGACAGA GCAGTGGGGA AAACTGTGAC 
GTGGTCGTCA ACACCCTGGG GAAGAGGGCC CCAGCCTTTG AGGGCAGGAT CCTGCTCAAC 
CCCCAGGACA AGGATGGCTC ATTCAGTGTG GTGATCACAG GCCTGAGGAA GGAGGATGCA 
GGGCGCTACC TGTGTGGAGC CCATTCGGAT GGTCAGCTGC AGGAAGGCTC GCCTATCCAG 
GCCTGGCAAC TCTTCGTCAA TGAGGAGTCC ACGATTCCCC GCAGCCCCAC TGTGGTGAAG 
GGGGTGGCAG GAGGCTCTGT GGCCGTGCTC TGCCCCTACA ACCGTAAGGA AAGCAAAAGC 
ATCAAGTACT GGTGTCTCTG GGAAGGGGCC CAGAATGGCC GCTGCCCCCT GCTGGTGGAC 
AGCGAGGGGT GGGTTAAGGC CCAGTACGAG GGCCGCCTCT CCCTGCTGGA GGAGCCAGGC 
AACGGCACCT TCACTGTCAT CCTCAACCAG CTCACCAGCC GGGACGCCGG CTTCTACTGG 
TGTCTGACCA ACGGCGATAC TCTCTGGAGG ACCACCGTGG AGATCAAGAT TATCGAAGGA 
GAACCAAACC TCAAGGTACC AGGGAATGTC ACGGCTGTGC TGGGAGAGAC TCTCAAGGTC 
CCCTGTCACT TTCCATGCAA ATTCTCCTCG TACGAGAAAT ACTGGTGCAA GTGGAATAAC 
ACGGGCTGCC AGGCCCTGCC CAGCCAAGAC GAAGGCCCCA GCAAGGCCTT CGTGAACTGT 
GACGAGAACA GCCGGCTTGT CTCCCTGACC CTGAACCTGG TGACCAGGGC TGATGAGGGC 
TGGTACTGGT GTGGAGTGAA GCAGGGCCAC TTCTATGGAG AGACTGCAGC CGTCTATGTG 
GCAGTTGAAG AGAGGAAGGC AGCGGGGTCC CGCGATGTCA GCCTAGCGAA GGCAGACGCT 
GCTCCTGATG AGAAGGTGCT AGACTCTGGT TTTCGGGAGA TTGAGAACAA AGCCATTCAG 
GATCCCAGGC TTTTTGCAGA GGAAAAGGCG GTGGCAGATA CAAGAGATCA AGCCGATGGG 
AGCAGAGCAT CTGTGGATTC CGGCAGCTCT GAGGAACAAG GTGGAAGCTC CAGAGCGCTG 
GTCTCCACCC TGGTGCCCCT GGGCCTGGTG CTGGCAGTGG GAGCCGTGGC TGTGGGGGTG 
GCCAGAGCCC GGCACAGGAA GAACGTCGAC CGAGTTTCAA TCAGAAGCTA CAGGACAGAC 
ATTAGCATGT CAGACTTCGA GAACTCCAGG GAATTTGGAG CCAATGACAA CATGGGAGCC 
TCTTCGATCA CTCAGGAGAC ATCCCTCGGA GGAAAAGAAG AGTTTGTTGC CACCACTGAG 
AGCACCACAG AGACCAAAGA ACCCAAGAAG GCAAAAAGGT CATCCAAGGA GGAAGCCGAG 
ATGGCCTACA AAGACTTCCT GCTCCAGTCC AGCACCGTGG CCGCCGAGGC CCAGGACGGC 
CCCCAGGAAG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIGR ( XM_011509629.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507931.1 Homo sapiens polymeric immunoglobulin receptor (PIGR), transcript variant X1, mRNA.

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CloneID	OHu19522
Clone ID Related Accession (Same CDS sequence)	NM_002644.3 , XM_011509629.1 , NM_002644.4
Accession Version	XM_011509629.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2295bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	polymeric immunoglobulin receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTCT TCGTGCTCAC CTGCCTGCTG GCGGTCTTCC CAGCCATCTC CACGAAGAGT 
CCCATATTTG GTCCCGAGGA GGTGAATAGT GTGGAAGGTA ACTCAGTGTC CATCACGTGC 
TACTACCCAC CCACCTCTGT CAACCGGCAC ACCCGGAAGT ACTGGTGCCG GCAGGGAGCT 
AGAGGTGGCT GCATAACCCT CATCTCCTCG GAGGGCTACG TCTCCAGCAA ATATGCAGGC 
AGGGCTAACC TCACCAACTT CCCGGAGAAC GGCACATTTG TGGTGAACAT TGCCCAGCTG 
AGCCAGGATG ACTCCGGGCG CTACAAGTGT GGCCTGGGCA TCAATAGCCG AGGCCTGTCC 
TTTGATGTCA GCCTGGAGGT CAGCCAGGGT CCTGGGCTCC TAAATGACAC TAAAGTCTAC 
ACAGTGGACC TGGGCAGAAC GGTGACCATC AACTGCCCTT TCAAGACTGA GAATGCTCAA 
AAGAGGAAGT CCTTGTACAA GCAGATAGGC CTGTACCCTG TGCTGGTCAT CGACTCCAGT 
GGTTATGTAA ATCCCAACTA TACAGGAAGA ATACGCCTTG ATATTCAGGG TACTGGCCAG 
TTACTGTTCA GCGTTGTCAT CAACCAACTC AGGCTCAGCG ATGCTGGGCA GTATCTCTGC 
CAGGCTGGGG ATGATTCCAA TAGTAATAAG AAGAATGCTG ACCTCCAAGT GCTAAAGCCC 
GAGCCCGAGC TGGTTTATGA AGACCTGAGG GGCTCAGTGA CCTTCCACTG TGCCCTGGGC 
CCTGAGGTGG CAAACGTGGC CAAATTTCTG TGCCGACAGA GCAGTGGGGA AAACTGTGAC 
GTGGTCGTCA ACACCCTGGG GAAGAGGGCC CCAGCCTTTG AGGGCAGGAT CCTGCTCAAC 
CCCCAGGACA AGGATGGCTC ATTCAGTGTG GTGATCACAG GCCTGAGGAA GGAGGATGCA 
GGGCGCTACC TGTGTGGAGC CCATTCGGAT GGTCAGCTGC AGGAAGGCTC GCCTATCCAG 
GCCTGGCAAC TCTTCGTCAA TGAGGAGTCC ACGATTCCCC GCAGCCCCAC TGTGGTGAAG 
GGGGTGGCAG GAGGCTCTGT GGCCGTGCTC TGCCCCTACA ACCGTAAGGA AAGCAAAAGC 
ATCAAGTACT GGTGTCTCTG GGAAGGGGCC CAGAATGGCC GCTGCCCCCT GCTGGTGGAC 
AGCGAGGGGT GGGTTAAGGC CCAGTACGAG GGCCGCCTCT CCCTGCTGGA GGAGCCAGGC 
AACGGCACCT TCACTGTCAT CCTCAACCAG CTCACCAGCC GGGACGCCGG CTTCTACTGG 
TGTCTGACCA ACGGCGATAC TCTCTGGAGG ACCACCGTGG AGATCAAGAT TATCGAAGGA 
GAACCAAACC TCAAGGTACC AGGGAATGTC ACGGCTGTGC TGGGAGAGAC TCTCAAGGTC 
CCCTGTCACT TTCCATGCAA ATTCTCCTCG TACGAGAAAT ACTGGTGCAA GTGGAATAAC 
ACGGGCTGCC AGGCCCTGCC CAGCCAAGAC GAAGGCCCCA GCAAGGCCTT CGTGAACTGT 
GACGAGAACA GCCGGCTTGT CTCCCTGACC CTGAACCTGG TGACCAGGGC TGATGAGGGC 
TGGTACTGGT GTGGAGTGAA GCAGGGCCAC TTCTATGGAG AGACTGCAGC CGTCTATGTG 
GCAGTTGAAG AGAGGAAGGC AGCGGGGTCC CGCGATGTCA GCCTAGCGAA GGCAGACGCT 
GCTCCTGATG AGAAGGTGCT AGACTCTGGT TTTCGGGAGA TTGAGAACAA AGCCATTCAG 
GATCCCAGGC TTTTTGCAGA GGAAAAGGCG GTGGCAGATA CAAGAGATCA AGCCGATGGG 
AGCAGAGCAT CTGTGGATTC CGGCAGCTCT GAGGAACAAG GTGGAAGCTC CAGAGCGCTG 
GTCTCCACCC TGGTGCCCCT GGGCCTGGTG CTGGCAGTGG GAGCCGTGGC TGTGGGGGTG 
GCCAGAGCCC GGCACAGGAA GAACGTCGAC CGAGTTTCAA TCAGAAGCTA CAGGACAGAC 
ATTAGCATGT CAGACTTCGA GAACTCCAGG GAATTTGGAG CCAATGACAA CATGGGAGCC 
TCTTCGATCA CTCAGGAGAC ATCCCTCGGA GGAAAAGAAG AGTTTGTTGC CACCACTGAG 
AGCACCACAG AGACCAAAGA ACCCAAGAAG GCAAAAAGGT CATCCAAGGA GGAAGCCGAG 
ATGGCCTACA AAGACTTCCT GCTCCAGTCC AGCACCGTGG CCGCCGAGGC CCAGGACGGC 
CCCCAGGAAG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507931.1
CDS	96..2390
Translation	MLLFVLTCLLAVFPAISTKSPIFGPEEVNSVEGNSVSITCYYPPTSVNRHTRKYWCRQGARGGCITLISSEGYVSSKYAGRANLTNFPENGTFVVNIAQLSQDDSGRYKCGLGINSRGLSFDVSLEVSQGPGLLNDTKVYTVDLGRTVTINCPFKTENAQKRKSLYKQIGLYPVLVIDSSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQYLCQAGDDSNSNKKNADLQVLKPEPELVYEDLRGSVTFHCALGPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAFEGRILLNPQDKDGSFSVVITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLCPYNRKESKSIKYWCLWEGAQNGRCPLLVDSEGWVKAQYEGRLSLLEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGEPNLKVPGNVTAVLGETLKVPCHFPCKFSSYEKYWCKWNNTGCQALPSQDEGPSKAFVNCDENSRLVSLTLNLVTRADEGWYWCGVKQGHFYGETAAVYVAVEERKAAGSRDVSLAKADAAPDEKVLDSGFREIENKAIQDPRLFAEEKAVADTRDQADGSRASVDSGSSEEQGGSSRALVSTLVPLGLVLAVGAVAVGVARARHRKNVDRVSIRSYRTDISMSDFENSREFGANDNMGASSITQETSLGGKEEFVATTESTTETKEPKKAKRSSKEEAEMAYKDFLLQSSTVAAEAQDGPQEA

Target ORF information:

RefSeq Version	XM_011509629.1
Organism	Homo sapiens(human)
Definition	Homo sapiens polymeric immunoglobulin receptor (PIGR), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509629.1

ORF Insert Sequence:

ATGCTGCTCT TCGTGCTCAC CTGCCTGCTG GCGGTCTTCC CAGCCATCTC CACGAAGAGT 
CCCATATTTG GTCCCGAGGA GGTGAATAGT GTGGAAGGTA ACTCAGTGTC CATCACGTGC 
TACTACCCAC CCACCTCTGT CAACCGGCAC ACCCGGAAGT ACTGGTGCCG GCAGGGAGCT 
AGAGGTGGCT GCATAACCCT CATCTCCTCG GAGGGCTACG TCTCCAGCAA ATATGCAGGC 
AGGGCTAACC TCACCAACTT CCCGGAGAAC GGCACATTTG TGGTGAACAT TGCCCAGCTG 
AGCCAGGATG ACTCCGGGCG CTACAAGTGT GGCCTGGGCA TCAATAGCCG AGGCCTGTCC 
TTTGATGTCA GCCTGGAGGT CAGCCAGGGT CCTGGGCTCC TAAATGACAC TAAAGTCTAC 
ACAGTGGACC TGGGCAGAAC GGTGACCATC AACTGCCCTT TCAAGACTGA GAATGCTCAA 
AAGAGGAAGT CCTTGTACAA GCAGATAGGC CTGTACCCTG TGCTGGTCAT CGACTCCAGT 
GGTTATGTAA ATCCCAACTA TACAGGAAGA ATACGCCTTG ATATTCAGGG TACTGGCCAG 
TTACTGTTCA GCGTTGTCAT CAACCAACTC AGGCTCAGCG ATGCTGGGCA GTATCTCTGC 
CAGGCTGGGG ATGATTCCAA TAGTAATAAG AAGAATGCTG ACCTCCAAGT GCTAAAGCCC 
GAGCCCGAGC TGGTTTATGA AGACCTGAGG GGCTCAGTGA CCTTCCACTG TGCCCTGGGC 
CCTGAGGTGG CAAACGTGGC CAAATTTCTG TGCCGACAGA GCAGTGGGGA AAACTGTGAC 
GTGGTCGTCA ACACCCTGGG GAAGAGGGCC CCAGCCTTTG AGGGCAGGAT CCTGCTCAAC 
CCCCAGGACA AGGATGGCTC ATTCAGTGTG GTGATCACAG GCCTGAGGAA GGAGGATGCA 
GGGCGCTACC TGTGTGGAGC CCATTCGGAT GGTCAGCTGC AGGAAGGCTC GCCTATCCAG 
GCCTGGCAAC TCTTCGTCAA TGAGGAGTCC ACGATTCCCC GCAGCCCCAC TGTGGTGAAG 
GGGGTGGCAG GAGGCTCTGT GGCCGTGCTC TGCCCCTACA ACCGTAAGGA AAGCAAAAGC 
ATCAAGTACT GGTGTCTCTG GGAAGGGGCC CAGAATGGCC GCTGCCCCCT GCTGGTGGAC 
AGCGAGGGGT GGGTTAAGGC CCAGTACGAG GGCCGCCTCT CCCTGCTGGA GGAGCCAGGC 
AACGGCACCT TCACTGTCAT CCTCAACCAG CTCACCAGCC GGGACGCCGG CTTCTACTGG 
TGTCTGACCA ACGGCGATAC TCTCTGGAGG ACCACCGTGG AGATCAAGAT TATCGAAGGA 
GAACCAAACC TCAAGGTACC AGGGAATGTC ACGGCTGTGC TGGGAGAGAC TCTCAAGGTC 
CCCTGTCACT TTCCATGCAA ATTCTCCTCG TACGAGAAAT ACTGGTGCAA GTGGAATAAC 
ACGGGCTGCC AGGCCCTGCC CAGCCAAGAC GAAGGCCCCA GCAAGGCCTT CGTGAACTGT 
GACGAGAACA GCCGGCTTGT CTCCCTGACC CTGAACCTGG TGACCAGGGC TGATGAGGGC 
TGGTACTGGT GTGGAGTGAA GCAGGGCCAC TTCTATGGAG AGACTGCAGC CGTCTATGTG 
GCAGTTGAAG AGAGGAAGGC AGCGGGGTCC CGCGATGTCA GCCTAGCGAA GGCAGACGCT 
GCTCCTGATG AGAAGGTGCT AGACTCTGGT TTTCGGGAGA TTGAGAACAA AGCCATTCAG 
GATCCCAGGC TTTTTGCAGA GGAAAAGGCG GTGGCAGATA CAAGAGATCA AGCCGATGGG 
AGCAGAGCAT CTGTGGATTC CGGCAGCTCT GAGGAACAAG GTGGAAGCTC CAGAGCGCTG 
GTCTCCACCC TGGTGCCCCT GGGCCTGGTG CTGGCAGTGG GAGCCGTGGC TGTGGGGGTG 
GCCAGAGCCC GGCACAGGAA GAACGTCGAC CGAGTTTCAA TCAGAAGCTA CAGGACAGAC 
ATTAGCATGT CAGACTTCGA GAACTCCAGG GAATTTGGAG CCAATGACAA CATGGGAGCC 
TCTTCGATCA CTCAGGAGAC ATCCCTCGGA GGAAAAGAAG AGTTTGTTGC CACCACTGAG 
AGCACCACAG AGACCAAAGA ACCCAAGAAG GCAAAAAGGT CATCCAAGGA GGAAGCCGAG 
ATGGCCTACA AAGACTTCCT GCTCCAGTCC AGCACCGTGG CCGCCGAGGC CCAGGACGGC 
CCCCAGGAAG CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]17(2)295-302(2017 Mar - Apr)
Arumugam P,Bhattacharya S,Chin-Aleong J,Capaso M,Kocher HM

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion.
The Journal of experimental medicine214(6)1619-1630(2017 Jun)
Iovino F,Engelen-Lee JY,Brouwer M,van de Beek D,van der Ende A,Valls Seron M,Mellroth P,Muschiol S,Bergstrand J,Widengren J,Henriques-Normark B

A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic.
PloS one12(3)e0173880(2017)
Ward-Caviness CK,Neas LM,Blach C,Haynes CS,LaRocque-Abramson K,Grass E,Dowdy ZE,Devlin RB,Diaz-Sanchez D,Cascio WE,Miranda ML,Gregory SG,Shah SH,Kraus WE,Hauser ER

Sentinel Lymph Node Genes to Predict Prognosis in Node-Positive Melanoma Patients.
Annals of surgical oncology24(1)108-116(2017 Jan)
Hao H,Xiao D,Pan J,Qu J,Egger M,Waigel S,Sanders MA,Zacharias W,Rai SN,McMasters KM

The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins.
eLife5(2016 Mar)
Stadtmueller BM,Huey-Tubman KE,L?pez CJ,Yang Z,Hubbell WL,Bjorkman PJ

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PIGR cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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