PFDN2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PFDN2
Entrez Gene ID	5202
Full Name	prefoldin subunit 2
Synonyms	PFD2
General protein information	Preferred Names prefoldin subunit 2 Names prefoldin subunit 2 prefoldin 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q23.3
Summary	This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008].
Disorder MIM:	613466

mRNA and Protein(s)

mRNA	Protein	Name
XM_011509624.2	XP_011507926.1	prefoldin subunit 2 isoform X1
XM_011509624.3	XP_011507926.1	prefoldin subunit 2 isoform X1
NM_012394.4	NP_036526.2	prefoldin subunit 2
NM_012394.3	NP_036526.2	prefoldin subunit 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PFDN2	NP_001073690.1
Danio rerio (zebrafish)	pfdn2	NP_001038754.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006070	XP_316121.4
Arabidopsis thaliana (thale cress)	PDF2	NP_850626.1
Oryza sativa (rice)	Os11g0568500	NP_001068114.1
Xenopus tropicalis (tropical clawed frog)	pfdn2	NP_001120494.1
Rattus norvegicus (Norway rat)	Pfdn2	NP_001102946.1
Gallus gallus (chicken)	PFDN2	XP_004948460.1
Oryza sativa (rice)	Os12g0485800	NP_001066784.1
Homo sapiens (human)	PFDN2	NP_036526.2
Canis lupus familiaris (dog)	PFDN2	XP_545765.2
Mus musculus (house mouse)	Pfdn2	NP_035200.2
Drosophila melanogaster (fruit fly)	l(3)01239	NP_001261696.1
Pan troglodytes (chimpanzee)	PFDN2	XP_513934.1
	PFDN2	XP_001117749.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Taipale M, Tucker G, Peng J, Krykbaeva I, Lin ZY, Larsen B, Choi H, Berger B, Gingras AC, Lindquist S
Cell158(2)434-448(2014 Jul)

Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA.
L?pez V, Gonz?lez-Peramato P, Suela J, Serrano A, Algaba F, Cigudosa JC, Vidal A, Bellmunt J, Heredero O, S?nchez-Carbayo M
Journal of translational medicine11182(2013 Aug)

Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation.
Tashiro E, Zako T, Muto H, Itoo Y, S?rgjerd K, Terada N, Abe A, Miyazawa M, Kitamura A, Kitaura H, Kubota H, Maeda M, Momoi T, Iguchi-Ariga SM, Kinjo M, Ariga H
The Journal of biological chemistry288(27)19958-72(2013 Jul)

High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.
Cloutier P, Al-Khoury R, Lavall?e-Adam M, Faubert D, Jiang H, Poitras C, Bouchard A, Forget D, Blanchette M, Coulombe B
Methods (San Diego, Calif.)48(4)381-6(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

prefoldin is amplified at 1q23.3-q24.1 in bladder cancer
Title: Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA.

knockdown of PFD2 and PFD5 disrupted prefoldin formation in HTT-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT and in induction of cell death.
Title: Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation.

Is part of an RNA polymerase II-associated complex with possible chaperone activity.
Title: High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.

The following PFDN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PFDN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06205	NM_012394.4 Latest version!	Homo sapiens prefoldin subunit 2 (PFDN2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu59622	XM_011509624.3 Latest version!	Homo sapiens prefoldin subunit 2 (PFDN2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OHu59622	XM_011509624.2	Homo sapiens prefoldin subunit 2 (PFDN2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu06205	NM_012394.3	Homo sapiens prefoldin subunit 2 (PFDN2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PFDN2 ( NM_012394.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036526.2 Homo sapiens prefoldin subunit 2 (PFDN2), mRNA.

Price & Availability↑

CloneID	OHu06205
Clone ID Related Accession (Same CDS sequence)	NM_012394.4 , NM_012394.3
Accession Version	NM_012394.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	prefoldin subunit 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC012464.1 and AF165883.1. On Nov 22, 2018 this sequence version replaced NM_012394.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047042.1, AK024531.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154529, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000368010.4/ ENSP00000356989.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGAGA ACAGCGGTCG CGCCGGCAAG AGCAGCGGGA GCGGCGCGGG GAAGGGGGCG 
GTGTCCGCAG AGCAGGTGAT TGCTGGCTTC AACCGCCTTC GGCAGGAACA GCGAGGCCTG 
GCATCCAAAG CAGCTGAGTT GGAGATGGAG TTGAATGAGC ACAGCCTAGT GATCGATACA 
CTGAAGGAGG TAGATGAAAC TCGTAAGTGC TACCGCATGG TTGGAGGAGT GCTGGTGGAG 
CGAACTGTCA AAGAGGTGCT GCCCGCTTTG GAGAACAACA AGGAGCAGAT ACAGAAGATC 
ATTGAGACAC TGACACAGCA GCTTCAGGCA AAGGGAAAAG AACTAAATGA ATTCCGGGAA 
AAGCACAACA TTCGTCTCAT GGGAGAAGAT GAGAAGCCAG CAGCCAAGGA AAACTCAGAA 
GGGGCTGGGG CTAAGGCCAG CTCAGCTGGA GTGTTGGTCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036526.2
CDS	12..476
Translation	MAENSGRAGKSSGSGAGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALENNKEQIQKIIETLTQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS

Target ORF information:

RefSeq Version	NM_012394.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prefoldin subunit 2 (PFDN2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012394.4

ORF Insert Sequence:

ATGGCGGAGA ACAGCGGTCG CGCCGGCAAG AGCAGCGGGA GCGGCGCGGG GAAGGGGGCG 
GTGTCCGCAG AGCAGGTGAT TGCTGGCTTC AACCGCCTTC GGCAGGAACA GCGAGGCCTG 
GCATCCAAAG CAGCTGAGTT GGAGATGGAG TTGAATGAGC ACAGCCTAGT GATCGATACA 
CTGAAGGAGG TAGATGAAAC TCGTAAGTGC TACCGCATGG TTGGAGGAGT GCTGGTGGAG 
CGAACTGTCA AAGAGGTGCT GCCCGCTTTG GAGAACAACA AGGAGCAGAT ACAGAAGATC 
ATTGAGACAC TGACACAGCA GCTTCAGGCA AAGGGAAAAG AACTAAATGA ATTCCGGGAA 
AAGCACAACA TTCGTCTCAT GGGAGAAGAT GAGAAGCCAG CAGCCAAGGA AAACTCAGAA 
GGGGCTGGGG CTAAGGCCAG CTCAGCTGGA GTGTTGGTCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PFDN2 ( NM_012394.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036526.2 Homo sapiens prefoldin subunit 2 (PFDN2), mRNA.

Price & Availability↑

CloneID	OHu06205
Clone ID Related Accession (Same CDS sequence)	NM_012394.4 , NM_012394.3
Accession Version	NM_012394.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	prefoldin subunit 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI597083.1, BC012464.1 and AF165883.1. On Feb 28, 2006 this sequence version replaced NM_012394.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF165883.1, BI597083.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154529, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGA ACAGCGGTCG CGCCGGCAAG AGCAGCGGGA GCGGCGCGGG GAAGGGGGCG 
GTGTCCGCAG AGCAGGTGAT TGCTGGCTTC AACCGCCTTC GGCAGGAACA GCGAGGCCTG 
GCATCCAAAG CAGCTGAGTT GGAGATGGAG TTGAATGAGC ACAGCCTAGT GATCGATACA 
CTGAAGGAGG TAGATGAAAC TCGTAAGTGC TACCGCATGG TTGGAGGAGT GCTGGTGGAG 
CGAACTGTCA AAGAGGTGCT GCCCGCTTTG GAGAACAACA AGGAGCAGAT ACAGAAGATC 
ATTGAGACAC TGACACAGCA GCTTCAGGCA AAGGGAAAAG AACTAAATGA ATTCCGGGAA 
AAGCACAACA TTCGTCTCAT GGGAGAAGAT GAGAAGCCAG CAGCCAAGGA AAACTCAGAA 
GGGGCTGGGG CTAAGGCCAG CTCAGCTGGA GTGTTGGTCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036526.2
CDS	51..515
Translation	MAENSGRAGKSSGSGAGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALENNKEQIQKIIETLTQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS

Target ORF information:

RefSeq Version	NM_012394.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prefoldin subunit 2 (PFDN2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012394.3

ORF Insert Sequence:

ATGGCGGAGA ACAGCGGTCG CGCCGGCAAG AGCAGCGGGA GCGGCGCGGG GAAGGGGGCG 
GTGTCCGCAG AGCAGGTGAT TGCTGGCTTC AACCGCCTTC GGCAGGAACA GCGAGGCCTG 
GCATCCAAAG CAGCTGAGTT GGAGATGGAG TTGAATGAGC ACAGCCTAGT GATCGATACA 
CTGAAGGAGG TAGATGAAAC TCGTAAGTGC TACCGCATGG TTGGAGGAGT GCTGGTGGAG 
CGAACTGTCA AAGAGGTGCT GCCCGCTTTG GAGAACAACA AGGAGCAGAT ACAGAAGATC 
ATTGAGACAC TGACACAGCA GCTTCAGGCA AAGGGAAAAG AACTAAATGA ATTCCGGGAA 
AAGCACAACA TTCGTCTCAT GGGAGAAGAT GAGAAGCCAG CAGCCAAGGA AAACTCAGAA 
GGGGCTGGGG CTAAGGCCAG CTCAGCTGGA GTGTTGGTCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PFDN2 ( XM_011509624.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507926.1 Homo sapiens prefoldin subunit 2 (PFDN2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu59622
Clone ID Related Accession (Same CDS sequence)	XM_011509624.2 , XM_011509624.3
Accession Version	XM_011509624.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	prefoldin subunit 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509624.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTTGA ATGAGCACAG CCTAGTGATC GATACACTGA AGGAGGTAGA TGAAACTCGT 
AAGTGCTACC GCATGGTTGG AGGAGTGCTG GTGGAGCGAA CTGTCAAAGA GGTGCTGCCC 
GCTTTGGAGA ACAACAAGGA GCAGATACAG AAGATCATTG AGACACTGAC ACAGCAGCTT 
CAGGCAAAGG GAAAAGAACT AAATGAATTC CGGGAAAAGC ACAACATTCG TCTCATGGGA 
GAAGATGAGA AGCCAGCAGC CAAGGAAAAC TCAGAAGGGG CTGGGGCTAA GGCCAGCTCA 
GCTGGAGTGT TGGTCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507926.1
CDS	208..528
Translation	MELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALENNKEQIQKIIETLTQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS

Target ORF information:

RefSeq Version	XM_011509624.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prefoldin subunit 2 (PFDN2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509624.2

ORF Insert Sequence:

ATGGAGTTGA ATGAGCACAG CCTAGTGATC GATACACTGA AGGAGGTAGA TGAAACTCGT 
AAGTGCTACC GCATGGTTGG AGGAGTGCTG GTGGAGCGAA CTGTCAAAGA GGTGCTGCCC 
GCTTTGGAGA ACAACAAGGA GCAGATACAG AAGATCATTG AGACACTGAC ACAGCAGCTT 
CAGGCAAAGG GAAAAGAACT AAATGAATTC CGGGAAAAGC ACAACATTCG TCTCATGGGA 
GAAGATGAGA AGCCAGCAGC CAAGGAAAAC TCAGAAGGGG CTGGGGCTAA GGCCAGCTCA 
GCTGGAGTGT TGGTCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PFDN2 ( XM_011509624.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507926.1 Homo sapiens prefoldin subunit 2 (PFDN2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu59622
Clone ID Related Accession (Same CDS sequence)	XM_011509624.2 , XM_011509624.3
Accession Version	XM_011509624.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	prefoldin subunit 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011509624.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTTGA ATGAGCACAG CCTAGTGATC GATACACTGA AGGAGGTAGA TGAAACTCGT 
AAGTGCTACC GCATGGTTGG AGGAGTGCTG GTGGAGCGAA CTGTCAAAGA GGTGCTGCCC 
GCTTTGGAGA ACAACAAGGA GCAGATACAG AAGATCATTG AGACACTGAC ACAGCAGCTT 
CAGGCAAAGG GAAAAGAACT AAATGAATTC CGGGAAAAGC ACAACATTCG TCTCATGGGA 
GAAGATGAGA AGCCAGCAGC CAAGGAAAAC TCAGAAGGGG CTGGGGCTAA GGCCAGCTCA 
GCTGGAGTGT TGGTCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507926.1
CDS	211..531
Translation	MELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALENNKEQIQKIIETLTQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS

Target ORF information:

RefSeq Version	XM_011509624.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prefoldin subunit 2 (PFDN2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509624.3

ORF Insert Sequence:

ATGGAGTTGA ATGAGCACAG CCTAGTGATC GATACACTGA AGGAGGTAGA TGAAACTCGT 
AAGTGCTACC GCATGGTTGG AGGAGTGCTG GTGGAGCGAA CTGTCAAAGA GGTGCTGCCC 
GCTTTGGAGA ACAACAAGGA GCAGATACAG AAGATCATTG AGACACTGAC ACAGCAGCTT 
CAGGCAAAGG GAAAAGAACT AAATGAATTC CGGGAAAAGC ACAACATTCG TCTCATGGGA 
GAAGATGAGA AGCCAGCAGC CAAGGAAAAC TCAGAAGGGG CTGGGGCTAA GGCCAGCTCA 
GCTGGAGTGT TGGTCTCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Cell158(2)434-448(2014 Jul)
Taipale M,Tucker G,Peng J,Krykbaeva I,Lin ZY,Larsen B,Choi H,Berger B,Gingras AC,Lindquist S

Identification of prefoldin amplification (1q23.3-q24.1) in bladder cancer using comparative genomic hybridization (CGH) arrays of urinary DNA.
Journal of translational medicine11182(2013 Aug)
L?pez V,Gonz?lez-Peramato P,Suela J,Serrano A,Algaba F,Cigudosa JC,Vidal A,Bellmunt J,Heredero O,S?nchez-Carbayo M

Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation.
The Journal of biological chemistry288(27)19958-72(2013 Jul)
Tashiro E,Zako T,Muto H,Itoo Y,S?rgjerd K,Terada N,Abe A,Miyazawa M,Kitamura A,Kitaura H,Kubota H,Maeda M,Momoi T,Iguchi-Ariga SM,Kinjo M,Ariga H

High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.
Methods (San Diego, Calif.)48(4)381-6(2009 Aug)
Cloutier P,Al-Khoury R,Lavall?e-Adam M,Faubert D,Jiang H,Poitras C,Bouchard A,Forget D,Blanchette M,Coulombe B

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PFDN2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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