ACP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACP1
Entrez Gene ID	52
Full Name	acid phosphatase 1
Synonyms	HAAP,LMW-PTP,LMWPTP
General protein information	Preferred Names acid phosphatase 1 Names low molecular weight phosphotyrosine protein phosphatase LMW-PTPase acid phosphatase 1, soluble acid phosphatase of erythrocyte adipocyte acid phosphatase cytoplasmic phosphotyrosyl protein phosphatase low molecular weight cytosolic acid phosphatase protein tyrosine phosphatase red cell acid phosphatase 1 testicular secretory protein Li 37
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p25.3
Summary	The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008].
Disorder MIM:	171500

mRNA and Protein(s)

mRNA	Protein	Name
NM_007099.3	NP_009030.1	low molecular weight phosphotyrosine protein phosphatase isoform b
XM_011510363.1	XP_011508665.1	low molecular weight phosphotyrosine protein phosphatase isoform X1
NM_004300.3	NP_004291.1	low molecular weight phosphotyrosine protein phosphatase isoform c
NM_004300.4	NP_004291.1	low molecular weight phosphotyrosine protein phosphatase isoform c
NM_001040649.2	NP_001035739.1	low molecular weight phosphotyrosine protein phosphatase isoform d

Pathways from BioSystems

Homologies

Homo sapiens (human)	ACP1	NP_004291.1
Drosophila melanogaster (fruit fly)	primo-1	NP_001027186.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004079	XP_309631.5
Caenorhabditis elegans (roundworm)	Y94H6A.7	NP_500246.5
Pan troglodytes (chimpanzee)	ACP1	XP_515271.3
Gallus gallus (chicken)	ACP1	NP_001034380.1
Mus musculus (house mouse)	Acp1	NP_067305.2
Danio rerio (zebrafish)	acp1	NP_001231711.1
Rattus norvegicus (Norway rat)	RGD1565965	XP_237746.2

Gene Ontology
Bibliography

Related articles in PubMed

Total Knockdown of LMW-PTP in MDA-MB-231 Cells Reduces Osteoclastogenesis.
Sapinho G, Alho I, Bicho M, Coelho C
Anticancer research37(12)6671-6677(2017 12)

Replication of rs300774, a genetic biomarker near ACP1, associated with suicide attempts in patients with schizophrenia: Relation to brain cholesterol biosynthesis.
Li J, Yoshikawa A, Meltzer HY
Journal of psychiatric research9454-61(2017 Nov)

Suicide behavior as a quantitative trait and its genetic background.
Pawlak J, Dmitrzak-Weglarz M, Wilkosc M, Szczepankiewicz A, Leszczynska-Rodziewicz A, Zaremba D, Kapelski P, Rajewska-Rager A, Hauser J
Journal of affective disorders206241-250(2016 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Conditioned medium from MDA-MB-231 breast cancer cells with total knockdown of LMW-PTP, but not of slow isoform LMW-PTP, significantly reduced osteoclast differentiation of RAW 264.7 cells.
Title: Total Knockdown of LMW-PTP in MDA-MB-231 Cells Reduces Osteoclastogenesis.

results confirm the role of TPH1, TPH2, 5HT2A, CRHR1 and ACP1 variants in the risk of suicidal behavior.
Title: Suicide behavior as a quantitative trait and its genetic background.

These data support that PTPN22 1858C/T, PTPRJ 2965C/G and 1176 A/C polymorphisms and ACP1 A, B and C alleles are not associated with a higher risk of immune thrombocytopenia P in adults.
Title: No impact of PTPN22, PTPRJ and ACP1 genes polymorphisms on the risk of immune thrombocytopenia in French adult patients.

The LMW-PTP slow isoform can be an important protein in bone metastatic disease, with a fundamental role in the interplay between tumor cells and osteoclasts, through the regulation of Src activity and IL-8 secretion.
Title: Low Molecular Weight Protein Tyrosine Phosphatase Slow Isoform Knockdown in MDA-MB-435 Cells Decreases RAW 264.7 Osteoclastic Differentiation.

Suggest that hypermethylation of ACP1, BMP4, and TSPYL5 are common events in HCC and could be used as potentially detectable biomarkers in HCC tissues.
Title: Hypermethylation of ACP1, BMP4, and TSPYL5 in Hepatocellular Carcinoma and Their Potential Clinical Significance.

The following ACP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13638	NM_007099.3 Latest version!	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu19593	NM_004300.4 Latest version!	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13638	XM_011510363.1 Latest version!	Homo sapiens acid phosphatase 1, soluble (ACP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13669	NM_001040649.2 Latest version!	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu19593	NM_004300.3	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACP1 ( NM_007099.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009030.1 Homo sapiens acid phosphatase 1 (ACP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13638
Clone ID Related Accession (Same CDS sequence)	NM_007099.3 , XM_011510363.1
Accession Version	NM_007099.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	low molecular weight phosphotyrosine protein phosphatase isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC079779.7, BC007422.2, M83654.1 and BX481618.1. On Aug 20, 2008 this sequence version replaced NM_007099.2. Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 4, one of which results in a translational frameshift. The resulting protein (isoform b, also known as Bs) has a distinct C-terminus and is longer than isoform d. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M83654.1, SRR1660809.111035.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
GTCATTGACA GCGGTGCTGT TTCTGACTGG AACGTGGGCC GGTCCCCAGA CCCAAGAGCT 
GTGAGCTGCC TAAGAAATCA TGGCATTCAC ACAGCCCATA AAGCAAGACA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009030.1
CDS	97..573
Translation	MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWVIDSGAVSDWNVGRSPDPRAVSCLRNHGIHTAHKARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH

Target ORF information:

RefSeq Version	NM_007099.3
Organism	Homo sapiens(human)
Definition	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007099.3

ORF Insert Sequence:

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
GTCATTGACA GCGGTGCTGT TTCTGACTGG AACGTGGGCC GGTCCCCAGA CCCAAGAGCT 
GTGAGCTGCC TAAGAAATCA TGGCATTCAC ACAGCCCATA AAGCAAGACA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACP1 ( NM_004300.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004291.1 Homo sapiens acid phosphatase 1 (ACP1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu19593
Clone ID Related Accession (Same CDS sequence)	NM_004300.3 , NM_004300.4
Accession Version	NM_004300.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	low molecular weight phosphotyrosine protein phosphatase isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC079779.7, AB209838.1, DB443811.1 and BX481618.1. This sequence is a reference standard in the RefSeqGene project. On Aug 20, 2008 this sequence version replaced NM_004300.2. Transcript Variant: This variant (3) has multiple differences in the coding region, compared to variant 4. The resulting protein (isoform c, also known as Bf) has a distinct C-terminus and is longer than isoform d. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.144188.1, SRR1803613.152841.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
AGGGTAGACA GCGCGGCAAC TTCCGGGTAT GAGATAGGGA ACCCCCCTGA CTACCGAGGG 
CAGAGCTGCA TGAAGAGGCA CGGCATTCCC ATGAGCCACG TTGCCCGGCA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004291.1
CDS	97..573
Translation	MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH

Target ORF information:

RefSeq Version	NM_004300.3
Organism	Homo sapiens(human)
Definition	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004300.3

ORF Insert Sequence:

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
AGGGTAGACA GCGCGGCAAC TTCCGGGTAT GAGATAGGGA ACCCCCCTGA CTACCGAGGG 
CAGAGCTGCA TGAAGAGGCA CGGCATTCCC ATGAGCCACG TTGCCCGGCA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACP1 ( NM_004300.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004291.1 Homo sapiens acid phosphatase 1 (ACP1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu19593
Clone ID Related Accession (Same CDS sequence)	NM_004300.3 , NM_004300.4
Accession Version	NM_004300.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	low molecular weight phosphotyrosine protein phosphatase isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB209838.1, DB443811.1 and BX481618.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_004300.3. Transcript Variant: This variant (3) has multiple differences in the coding region, compared to variant 4. The resulting protein (isoform c, also known as Bf) has a distinct C-terminus and is longer than isoform d. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1092612.1, SRR3476690.449309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000272065.10/ ENSP00000272065.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
AGGGTAGACA GCGCGGCAAC TTCCGGGTAT GAGATAGGGA ACCCCCCTGA CTACCGAGGG 
CAGAGCTGCA TGAAGAGGCA CGGCATTCCC ATGAGCCACG TTGCCCGGCA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004291.1
CDS	19..495
Translation	MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH

Target ORF information:

RefSeq Version	NM_004300.4
Organism	Homo sapiens(human)
Definition	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004300.4

ORF Insert Sequence:

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
AGGGTAGACA GCGCGGCAAC TTCCGGGTAT GAGATAGGGA ACCCCCCTGA CTACCGAGGG 
CAGAGCTGCA TGAAGAGGCA CGGCATTCCC ATGAGCCACG TTGCCCGGCA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACP1 ( XM_011510363.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508665.1 Homo sapiens acid phosphatase 1, soluble (ACP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu13638
Clone ID Related Accession (Same CDS sequence)	NM_007099.3 , XM_011510363.1
Accession Version	XM_011510363.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	low molecular weight phosphotyrosine protein phosphatase isoform X1
Comment

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
GTCATTGACA GCGGTGCTGT TTCTGACTGG AACGTGGGCC GGTCCCCAGA CCCAAGAGCT 
GTGAGCTGCC TAAGAAATCA TGGCATTCAC ACAGCCCATA AAGCAAGACA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508665.1
Translation	MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWVIDSGAVSDWNVGRSPDPRAVSCLRNHGIHTAHKARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH

Target ORF information:

RefSeq Version	XM_011510363.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens acid phosphatase 1, soluble (ACP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011510363.1

ORF Insert Sequence:

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
GTCATTGACA GCGGTGCTGT TTCTGACTGG AACGTGGGCC GGTCCCCAGA CCCAAGAGCT 
GTGAGCTGCC TAAGAAATCA TGGCATTCAC ACAGCCCATA AAGCAAGACA GATTACCAAA 
GAAGATTTTG CCACATTTGA TTATATACTA TGTATGGATG AAAGCAATCT GAGAGATTTG 
AATAGAAAAA GTAATCAAGT TAAAACCTGC AAAGCTAAAA TTGAACTACT TGGGAGCTAT 
GATCCACAAA AACAACTTAT TATTGAAGAT CCCTATTATG GGAATGACTC TGACTTTGAG 
ACGGTGTACC AGCAGTGTGT CAGGTGCTGC AGAGCGTTCT TGGAGAAGGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACP1 ( NM_001040649.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035739.1 Homo sapiens acid phosphatase 1 (ACP1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu13669
Clone ID Related Accession (Same CDS sequence)	NM_001040649.2
Accession Version	NM_001040649.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 339bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	low molecular weight phosphotyrosine protein phosphatase isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC079779.7 and DA378283.1. On Aug 20, 2008 this sequence version replaced NM_001040649.1. Transcript Variant: This variant (4) represents the shortest transcript and encodes the shortest isoform (d). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM005577.1, BP363227.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
AGGGTAGACA GCGCGGCAAC TTCCGGGTAT GAGATAGGGA ACCCCCCTGA CTACCGAGGG 
CAGAGCTGCA TGAAGAGGCA CGGCATTCCC ATGAGCCACG TTGCCCGGCA GGTACCGTCC 
TTGGACTTGA AGTTGTGTGT TTTGTGTTTC AGTGGGTCAT TGACAGCGGT GCTGTTTCTG 
ACTGGAACGT GGGCCGGTCC CCAGACCCAA GAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035739.1
CDS	97..435
Translation	MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQVPSLDLKLCVLCFSGSLTAVLFLTGTWAGPQTQEL

Target ORF information:

RefSeq Version	NM_001040649.2
Organism	Homo sapiens(human)
Definition	Homo sapiens acid phosphatase 1 (ACP1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040649.2

ORF Insert Sequence:

ATGGCGGAAC AGGCTACCAA GTCCGTGCTG TTTGTGTGTC TGGGTAACAT TTGTCGATCA 
CCCATTGCAG AAGCAGTTTT CAGGAAACTT GTAACCGATC AAAACATCTC AGAGAATTGG 
AGGGTAGACA GCGCGGCAAC TTCCGGGTAT GAGATAGGGA ACCCCCCTGA CTACCGAGGG 
CAGAGCTGCA TGAAGAGGCA CGGCATTCCC ATGAGCCACG TTGCCCGGCA GGTACCGTCC 
TTGGACTTGA AGTTGTGTGT TTTGTGTTTC AGTGGGTCAT TGACAGCGGT GCTGTTTCTG 
ACTGGAACGT GGGCCGGTCC CCAGACCCAA GAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Total Knockdown of LMW-PTP in MDA-MB-231 Cells Reduces Osteoclastogenesis.
Anticancer research37(12)6671-6677(2017 12)
Sapinho G,Alho I,Bicho M,Coelho C

Replication of rs300774, a genetic biomarker near ACP1, associated with suicide attempts in patients with schizophrenia: Relation to brain cholesterol biosynthesis.
Journal of psychiatric research9454-61(2017 Nov)
Li J,Yoshikawa A,Meltzer HY

Suicide behavior as a quantitative trait and its genetic background.
Journal of affective disorders206241-250(2016 Dec)
Pawlak J,Dmitrzak-Weglarz M,Wilkosc M,Szczepankiewicz A,Leszczynska-Rodziewicz A,Zaremba D,Kapelski P,Rajewska-Rager A,Hauser J

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ACP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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