CFP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CFP
Entrez Gene ID	5199
Full Name	complement factor properdin
Synonyms	BFD,PFC,PFD,PROPERDIN
General protein information	Preferred Names complement factor properdin Names properdin complement factor P properdin P factor, complement
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.23
Summary	This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009].
Disorder MIM:	300383
Disorder Html:	Properdin deficiency, X-linked, 312060 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001145252.1	NP_001138724.1	properdin precursor
NM_001145252.3	NP_001138724.1	properdin precursor
NM_002621.2	NP_002612.1	properdin precursor
NM_001145252.2	NP_001138724.1	properdin precursor
XM_017029575.1	XP_016885064.1	properdin isoform X1

Pathways from BioSystems

Homologies

	LOC707386	XP_002806283.1
Canis lupus familiaris (dog)	CFP	XP_548978.2
Rattus norvegicus (Norway rat)	Cfp	NP_001100227.1
Danio rerio (zebrafish)	si:ch73-237c6.1	NP_001107051.1
Danio rerio (zebrafish)	cfp	NP_001153598.1
Bos taurus (cattle)	CFP	NP_001069646.1
Pan troglodytes (chimpanzee)	CFP	XP_001136665.1
Homo sapiens (human)	CFP	NP_001138724.1
Mus musculus (house mouse)	Cfp	NP_032849.2

Gene Ontology
Bibliography

Related articles in PubMed

Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection.
Marr?n-Li?ares GM, N??ez L, Crespo-Leiro MG, Barge-Caballero E, Pombo J, Paniagua-Martin MJ, Suarez-Fuentetaja N, Cid J, Grille-Cancela Z, Mu?iz-Garcia J, Tan CD, Rodr?guez ER, V?zquez-Rodr?guez JM, Hermida-Prieto M
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation(2017 Jul)

Functional and structural insight into properdin control of complement alternative pathway amplification.
Pedersen DV, Roumenina L, Jensen RK, Gadeberg TA, Marinozzi C, Picard C, Rybkine T, Thiel S, S?rensen UB, Stover C, Fremeaux-Bacchi V, Andersen GR
The EMBO journal36(8)1084-1099(2017 04)

Complement factor P is a ligand for the natural killer cell-activating receptor NKp46.
Narni-Mancinelli E, Gauthier L, Baratin M, Guia S, Fenis A, Deghmane AE, Rossi B, Fourquet P, Escali?re B, Kerdiles YM, Ugolini S, Taha MK, Vivier E
Science immunology2(10)(2017 Apr)

Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-?.
Dixon KO, O'Flynn J, Klar-Mohamad N, Daha MR, van Kooten C
European journal of immunology47(3)470-480(2017 03)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

studies demonstrate an essential role of properdin oligomerization in vivo while our monomers enable detailed structural insight paving the way for novel modulators of complement.
Title: Functional and structural insight into properdin control of complement alternative pathway amplification.

this study shows that RNA interference of properdin in dendritic cells decreased alloantigen-specific T-cell proliferation
Title: Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-?.

data indicate that properdin enhances platelet/granulocyte aggregates (PGAs) formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation
Title: Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood.

P serum level expression could be a reliable clinical biomarker to identify patients with underlying surface alternative pathway C5 convertase dysregulation.
Title: Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy.

In the pathogenesis of renal tubular damage, P can directly bind to PTECs and may accelerate AP activation by surpassing fH regulation
Title: Properdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage.

The following CFP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CFP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02489	NM_001145252.3 Latest version!	Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu02489	NM_002621.2 Latest version!	Homo sapiens complement factor properdin (CFP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu99332	XM_017029575.1 Latest version!	Homo sapiens complement factor properdin (CFP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu02489	NM_001145252.1	Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu02489	NM_001145252.2	Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CFP ( NM_001145252.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138724.1 Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02489
Clone ID Related Accession (Same CDS sequence)	NM_001145252.1 , NM_001145252.3 , NM_002621.2 , NM_001145252.2
Accession Version	NM_001145252.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	properdin precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB146591.1, X57748.1 and BC015756.1. Transcript Variant: This variant (2) differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015756.1, SRR1163658.505705.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138724.1
CDS	127..1536
Translation	MITEGAQAPRLLLPPLLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL

Target ORF information:

RefSeq Version	NM_001145252.1
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145252.1

ORF Insert Sequence:

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFP ( NM_001145252.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138724.1 Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02489
Clone ID Related Accession (Same CDS sequence)	NM_001145252.1 , NM_001145252.3 , NM_002621.2 , NM_001145252.2
Accession Version	NM_001145252.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	properdin precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB146591.1, X57748.1, BC015756.1 and AL009172.1. On Aug 7, 2019 this sequence version replaced NM_001145252.2. Transcript Variant: This variant (2) differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015756.1, M83652.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138724.1
CDS	87..1496
Translation	MITEGAQAPRLLLPPLLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL

Target ORF information:

RefSeq Version	NM_001145252.3
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145252.3

ORF Insert Sequence:

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFP ( NM_002621.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002612.1 Homo sapiens complement factor properdin (CFP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02489
Clone ID Related Accession (Same CDS sequence)	NM_001145252.1 , NM_001145252.3 , NM_002621.2 , NM_001145252.2
Accession Version	NM_002621.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	properdin precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL009172.1, X57748.1 and BC015756.1. This sequence is a reference standard in the RefSeqGene project. On Feb 18, 2009 this sequence version replaced NM_002621.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: X57748.1, SRR1163657.447380.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002612.1
CDS	243..1652
Translation	MITEGAQAPRLLLPPLLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL

Target ORF information:

RefSeq Version	NM_002621.2
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor properdin (CFP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002621.2

ORF Insert Sequence:

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFP ( NM_001145252.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138724.1 Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.

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CloneID	OHu02489
Clone ID Related Accession (Same CDS sequence)	NM_001145252.1 , NM_001145252.3 , NM_002621.2 , NM_001145252.2
Accession Version	NM_001145252.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	properdin precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB146591.1, X57748.1, BC015756.1 and AL009172.1. On Jun 2, 2019 this sequence version replaced NM_001145252.1. Transcript Variant: This variant (2) differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015756.1, M83652.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138724.1
CDS	87..1496
Translation	MITEGAQAPRLLLPPLLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSVEDCCLNTAFAYQKRSGGLCQPCRSPRWSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQCCPEMGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL

Target ORF information:

RefSeq Version	NM_001145252.2
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor properdin (CFP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145252.2

ORF Insert Sequence:

ATGATCACAG AGGGAGCGCA GGCCCCTCGA TTGTTGCTGC CGCCGCTGCT CCTGCTGCTC 
ACCCTGCCAG CCACAGGCTC AGACCCCGTG CTCTGCTTCA CCCAGTATGA AGAATCCTCC 
GGCAAGTGCA AGGGCCTCCT GGGGGGTGGT GTCAGCGTGG AAGACTGCTG TCTCAACACT 
GCCTTTGCCT ACCAGAAACG TAGTGGTGGG CTCTGTCAGC CTTGCAGGTC CCCACGATGG 
TCCCTGTGGT CCACATGGGC CCCCTGTTCG GTGACGTGCT CTGAGGGCTC CCAGCTGCGG 
TACCGGCGCT GTGTGGGCTG GAATGGGCAG TGCTCTGGAA AGGTGGCACC TGGGACCCTG 
GAGTGGCAGC TCCAGGCCTG TGAGGACCAG CAGTGCTGTC CTGAGATGGG CGGCTGGTCT 
GGCTGGGGGC CCTGGGAGCC TTGCTCTGTC ACCTGCTCCA AAGGGACCCG GACCCGCAGG 
CGAGCCTGTA ATCACCCTGC TCCCAAGTGT GGGGGCCACT GCCCAGGACA GGCACAGGAA 
TCAGAGGCCT GTGACACCCA GCAGGTCTGC CCCACACACG GGGCCTGGGC CACCTGGGGC 
CCCTGGACCC CCTGCTCAGC CTCCTGCCAC GGTGGACCCC ACGAACCTAA GGAGACACGA 
AGCCGCAAGT GTTCTGCACC TGAGCCCTCC CAGAAACCTC CTGGGAAGCC CTGCCCGGGG 
CTAGCCTACG AGCAGCGGAG GTGCACCGGC CTGCCACCCT GCCCAGTGGC TGGGGGCTGG 
GGGCCTTGGG GCCCTGTGAG CCCCTGCCCT GTGACCTGTG GCCTGGGCCA GACCATGGAA 
CAACGGACGT GCAATCACCC TGTGCCCCAG CATGGGGGCC CCTTCTGTGC TGGCGATGCC 
ACCCGGACCC ACATCTGCAA CACAGCTGTG CCCTGCCCTG TGGATGGGGA GTGGGACTCG 
TGGGGGGAGT GGAGCCCCTG TATCCGACGG AACATGAAGT CCATCAGCTG TCAAGAAATC 
CCGGGCCAGC AGTCACGCGG GAGGACCTGC AGGGGCCGCA AGTTTGACGG ACATCGATGT 
GCCGGGCAAC AGCAGGATAT CCGGCACTGC TACAGCATCC AGCACTGCCC CTTGAAAGGA 
TCATGGTCAG AGTGGAGTAC CTGGGGGCTG TGCATGCCCC CCTGTGGACC TAATCCTACC 
CGTGCCCGCC AGCGCCTCTG CACACCCTTG CTCCCCAAGT ACCCGCCCAC CGTTTCCATG 
GTCGAAGGTC AGGGCGAGAA GAACGTGACC TTCTGGGGGA GACCGCTGCC ACGGTGTGAG 
GAGCTACAAG GGCAGAAGCT GGTGGTGGAG GAGAAACGAC CATGTCTACA CGTGCCTGCT 
TGCAAAGACC CTGAGGAAGA GGAACTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFP ( XM_017029575.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885064.1 Homo sapiens complement factor properdin (CFP), transcript variant X1, mRNA.

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CloneID	OHu99332
Clone ID Related Accession (Same CDS sequence)	XM_017029575.1
Accession Version	XM_017029575.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	properdin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGGCT GGTCTGGCTG GGGGCCCTGG GAGCCTTGCT CTGTCACCTG CTCCAAAGGG 
ACCCGGACCC GCAGGCGAGC CTGTAATCAC CCTGCTCCCA AGTGTGGGGG CCACTGCCCA 
GGACAGGCAC AGGAATCAGA GGCCTGTGAC ACCCAGCAGG TCTGCCCCAC ACACGGGGCC 
TGGGCCACCT GGGGCCCCTG GACCCCCTGC TCAGCCTCCT GCCACGGTGG ACCCCACGAA 
CCTAAGGAGA CACGAAGCCG CAAGTGTTCT GCACCTGAGC CCTCCCAGAA ACCTCCTGGG 
AAGCCCTGCC CGGGGCTAGC CTACGAGCAG CGGAGGTGCA CCGGCCTGCC ACCCTGCCCA 
GTGGCTGGGG GCTGGGGGCC TTGGGGCCCT GTGAGCCCCT GCCCTGTGAC CTGTGGCCTG 
GGCCAGACCA TGGAACAACG GACGTGCAAT CACCCTGTGC CCCAGCATGG GGGCCCCTTC 
TGTGCTGGCG ATGCCACCCG GACCCACATC TGCAACACAG CTGTGCCCTG CCCTGTGGAT 
GGGGAGTGGG ACTCGTGGGG GGAGTGGAGC CCCTGTATCC GACGGAACAT GAAGTCCATC 
AGCTGTCAAG AAATCCCGGG CCAGCAGTCA CGCGGGAGGA CCTGCAGGGG CCGCAAGTTT 
GACGGACATC GATGTGCCGG GCAACAGCAG GATATCCGGC ACTGCTACAG CATCCAGCAC 
TGCCCCTTGA AAGGATCATG GTCAGAGTGG AGTACCTGGG GGCTGTGCAT GCCCCCCTGT 
GGACCTAATC CTACCCGTGC CCGCCAGCGC CTCTGCACAC CCTTGCTCCC CAAGTACCCG 
CCCACCGTTT CCATGGTCGA AGGTCAGGGC GAGAAGAACG TGACCTTCTG GGGGAGACCG 
CTGCCACGGT GTGAGGAGCT ACAAGGGCAG AAGCTGGTGG TGGAGGAGAA ACGACCATGT 
CTACACGTGC CTGCTTGCAA AGACCCTGAG GAAGAGGAAC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885064.1
CDS	1154..2158
Translation	MGGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQESEACDTQQVCPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGRKFDGHRCAGQQQDIRHCYSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKYPPTVSMVEGQGEKNVTFWGRPLPRCEELQGQKLVVEEKRPCLHVPACKDPEEEEL

Target ORF information:

RefSeq Version	XM_017029575.1
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor properdin (CFP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029575.1

ORF Insert Sequence:

ATGGGCGGCT GGTCTGGCTG GGGGCCCTGG GAGCCTTGCT CTGTCACCTG CTCCAAAGGG 
ACCCGGACCC GCAGGCGAGC CTGTAATCAC CCTGCTCCCA AGTGTGGGGG CCACTGCCCA 
GGACAGGCAC AGGAATCAGA GGCCTGTGAC ACCCAGCAGG TCTGCCCCAC ACACGGGGCC 
TGGGCCACCT GGGGCCCCTG GACCCCCTGC TCAGCCTCCT GCCACGGTGG ACCCCACGAA 
CCTAAGGAGA CACGAAGCCG CAAGTGTTCT GCACCTGAGC CCTCCCAGAA ACCTCCTGGG 
AAGCCCTGCC CGGGGCTAGC CTACGAGCAG CGGAGGTGCA CCGGCCTGCC ACCCTGCCCA 
GTGGCTGGGG GCTGGGGGCC TTGGGGCCCT GTGAGCCCCT GCCCTGTGAC CTGTGGCCTG 
GGCCAGACCA TGGAACAACG GACGTGCAAT CACCCTGTGC CCCAGCATGG GGGCCCCTTC 
TGTGCTGGCG ATGCCACCCG GACCCACATC TGCAACACAG CTGTGCCCTG CCCTGTGGAT 
GGGGAGTGGG ACTCGTGGGG GGAGTGGAGC CCCTGTATCC GACGGAACAT GAAGTCCATC 
AGCTGTCAAG AAATCCCGGG CCAGCAGTCA CGCGGGAGGA CCTGCAGGGG CCGCAAGTTT 
GACGGACATC GATGTGCCGG GCAACAGCAG GATATCCGGC ACTGCTACAG CATCCAGCAC 
TGCCCCTTGA AAGGATCATG GTCAGAGTGG AGTACCTGGG GGCTGTGCAT GCCCCCCTGT 
GGACCTAATC CTACCCGTGC CCGCCAGCGC CTCTGCACAC CCTTGCTCCC CAAGTACCCG 
CCCACCGTTT CCATGGTCGA AGGTCAGGGC GAGAAGAACG TGACCTTCTG GGGGAGACCG 
CTGCCACGGT GTGAGGAGCT ACAAGGGCAG AAGCTGGTGG TGGAGGAGAA ACGACCATGT 
CTACACGTGC CTGCTTGCAA AGACCCTGAG GAAGAGGAAC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation(2017 Jul)
Marr?n-Li?ares GM,N??ez L,Crespo-Leiro MG,Barge-Caballero E,Pombo J,Paniagua-Martin MJ,Suarez-Fuentetaja N,Cid J,Grille-Cancela Z,Mu?iz-Garcia J,Tan CD,Rodr?guez ER,V?zquez-Rodr?guez JM,Hermida-Prieto M

Functional and structural insight into properdin control of complement alternative pathway amplification.
The EMBO journal36(8)1084-1099(2017 04)
Pedersen DV,Roumenina L,Jensen RK,Gadeberg TA,Marinozzi C,Picard C,Rybkine T,Thiel S,S?rensen UB,Stover C,Fremeaux-Bacchi V,Andersen GR

Complement factor P is a ligand for the natural killer cell-activating receptor NKp46.
Science immunology2(10)(2017 Apr)
Narni-Mancinelli E,Gauthier L,Baratin M,Guia S,Fenis A,Deghmane AE,Rossi B,Fourquet P,Escali?re B,Kerdiles YM,Ugolini S,Taha MK,Vivier E

Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-?.
European journal of immunology47(3)470-480(2017 03)
Dixon KO,O'Flynn J,Klar-Mohamad N,Daha MR,van Kooten C

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CFP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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