PEX13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PEX13
Entrez Gene ID	5194
Full Name	peroxisomal biogenesis factor 13
Synonyms	NALD,PBD11A,PBD11B,ZWS
General protein information	Preferred Names peroxisomal biogenesis factor 13 Names peroxisome biogenesis factor 13 peroxin-13 peroxisomal membrane protein PEX13
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p15
Summary	This gene encodes a peroxisomal membrane protein that binds the type 1 peroxisomal targeting signal receptor via a SH3 domain located in the cytoplasm. Mutations and deficiencies in peroxisomal protein importing and peroxisome assembly lead to peroxisomal biogenesis disorders, an example of which is Zellweger syndrome. [provided by RefSeq, Oct 2008].
Disorder MIM:	601789
Disorder Html:	Peroxisome biogenesis disorder 11A (Zellweger), 614883 (3); Peroxisome biogenesis disorder 11B, 614885 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002618.3	NP_002609.1	peroxisome biogenesis factor 13
NM_002618.4	NP_002609.1	peroxisome biogenesis factor 13

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PEX13	XP_525763.2
Canis lupus familiaris (dog)	PEX13	XP_005626180.1
Bos taurus (cattle)	PEX13	NP_001069680.1
Rattus norvegicus (Norway rat)	Pex13	NP_001100712.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010074	XP_319231.4
	PEX13	XP_001115402.1
Drosophila melanogaster (fruit fly)	Pex13	NP_610850.1
Xenopus tropicalis (tropical clawed frog)	pex13	XP_002939552.1
Caenorhabditis elegans (roundworm)	prx-13	NP_495513.1
Mus musculus (house mouse)	Pex13	NP_076140.2
Danio rerio (zebrafish)	pex13	NP_956939.1
Homo sapiens (human)	PEX13	NP_002609.1
Gallus gallus (chicken)	PEX13	NP_001186350.1

Gene Ontology
Bibliography

Related articles in PubMed

The peroxisomal matrix protein translocon is a large cavity-forming protein assembly into which PEX5 protein enters to release its cargo.
Dias AF, Rodrigues TA, Pedrosa AG, Barros-Barbosa A, Francisco T, Azevedo JE
The Journal of biological chemistry292(37)15287-15300(2017 09)

Peroxisomal protein PEX13 functions in selective autophagy.
Lee MY, Sumpter R Jr, Zou Z, Sirasanagandla S, Wei Y, Mishra P, Rosewich H, Crane DI, Levine B
EMBO reports18(1)48-60(2017 01)

Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.
Krause C, Rosewich H, Woehler A, G?rtner J
Human molecular genetics22(19)3844-57(2013 Oct)

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant SR, Bressman S, Burns ER, Chowers Y, Clark LN, Darvasi A, Doheny D, Duerr RH, Eliakim R, Giladi N, Gregersen PK, Hakonarson H, Jones MR, Marder K, McGovern DP, Mulle J, Orr-Urtreger A, Proctor DD, Pulver A, Rotter JI, Silverberg MS, Ullman T, Warren ST, Waterman M, Zhang W, Bergman A, Mayer L, Katz S, Desnick RJ, Cho JH, Peter I
PLoS genetics8(3)e1002559(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that soluble/cytosolic PEX5 interacts with PEX14/PEX13 complex, a model for the docking/translocation module (DTM) of the peroxisomal matrix protein translocon; PEX14/PEX13 complex appears to function in peroxisomal membrane as large cavity into which cytosolic PEX5 can enter to release its cargo. (PEX = peroxisomal biogenesis factor)
Title: The peroxisomal matrix protein translocon is a large cavity-forming protein assembly into which PEX5 protein enters to release its cargo.

our results demonstrate that PEX13 is required for selective autophagy, and suggest that dysregulation of PEX13-mediated mitophagy may contribute to ZSS pathogenesis.
Title: Peroxisomal protein PEX13 functions in selective autophagy.

Results show PEX13 interacts with itself in peroxisomes in living cells and the import of PTS1 (peroxisomal targeting signal 1) proteins is specifically disrupted when homooligomerization of PEX13 is interrupted.
Title: Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.

Zellweger syndrome caused by PEX13 deficiency: report of two novel mutations.
Title: Zellweger syndrome caused by PEX13 deficiency: report of two novel mutations.

analysis of PEX13 substitution of Ile326 by threonine in a patient with peroxisomal biogenesis disorder [case report]
Title: Molecular mechanism of a temperature-sensitive phenotype in peroxisomal biogenesis disorder.

The following PEX13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PEX13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26217	NM_002618.4 Latest version!	Homo sapiens peroxisomal biogenesis factor 13 (PEX13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu26217	NM_002618.3	Homo sapiens peroxisomal biogenesis factor 13 (PEX13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PEX13 ( NM_002618.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002609.1 Homo sapiens peroxisomal biogenesis factor 13 (PEX13), mRNA.

Price & Availability↑

CloneID	OHu26217
Clone ID Related Accession (Same CDS sequence)	NM_002618.3 , NM_002618.4
Accession Version	NM_002618.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-27
Organism	Homo sapiens(human)
Product	peroxisome biogenesis factor 13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB102467.1, AB022192.1, AC010733.8 and CN288682.1. This sequence is a reference standard in the RefSeqGene project. On Sep 30, 2008 this sequence version replaced NM_002618.2. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.7239.1, SRR1660807.48826.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCCC AGCCGCCACC TCCCCCCAAA CCCTGGGAGA CCCGCCGAAT TCCGGGAGCC 
GGACCGGGAC CAGGACCGGG CCCCACTTTC CAATCTGCTG ATTTGGGTCC TACTTTAATG 
ACAAGACCTG GACAACCAGC ACTTACCAGA GTGCCCCCAC CTATTCTTCC AAGGCCATCA 
CAGCAGACAG GAAGTAGCAG TGTGAACACT TTTAGACCTG CTTACAGTTC ATTTTCTTCT 
GGATATGGTG CCTATGGAAA TTCATTTTAT GGAGGCTATA GTCCTTATAG TTATGGATAT 
AATGGGCTGG GCTACAACCG CCTCCGTGTA GATGATCTTC CACCCAGTAG ATTTGTTCAG 
CAAGCTGAAG AAAGCAGCAG GGGTGCATTT CAGTCCATTG AAAGTATTGT GCATGCATTT 
GCCTCTGTCA GTATGATGAT GGATGCTACC TTTTCAGCTG TCTATAACAG TTTCAGGGCT 
GTATTGGATG TAGCAAATCA CTTTTCCCGA TTGAAAATAC ACTTTACAAA AGTGTTTTCA 
GCTTTTGCAT TGGTTAGGAC TATACGGTAT CTTTACAGAC GGCTACAGCG GATGTTAGGT 
TTAAGAAGAG GCTCTGAGAA TGAAGACCTC TGGGCAGAGA GTGAAGGAAC TGTGGCATGC 
CTTGGTGCTG AGGACCGAGC AGCTACCTCA GCAAAATCTT GGCCAATATT CTTGTTCTTT 
GCTGTTATCC TTGGTGGTCC TTACCTCATT TGGAAACTAT TGTCTACTCA CAGTGATGAA 
GTAACAGACA GCATCAACTG GGCAAGTGGT GAGGATGACC ATGTAGTTGC CAGAGCAGAA 
TATGATTTTG CTGCCGTATC TGAAGAAGAA ATTTCTTTCC GGGCTGGTGA TATGCTGAAC 
TTAGCTCTCA AAGAACAACA ACCCAAAGTG CGTGGTTGGC TTCTGGCTAG CCTTGATGGC 
CAAACAACAG GACTTATACC TGCGAATTAT GTCAAAATTC TTGGCAAAAG AAAAGGTAGG 
AAAACGGTGG AATCAAGTAA AGTTTCCAAG CAGCAACAAT CTTTTACCAA CCCAACACTA 
ACTAAAGGAG CCACGGTTGC TGATTCTTTG GATGAACAGG AAGCTGCCTT TGAATCTGTT 
TTTGTTGAAA CTAATAAGGT TCCAGTTGCA CCTGATTCCA TTGGGAAAGA TGGAGAAAAG 
CAAGATCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002609.1
CDS	84..1295
Translation	MASQPPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPALTRVPPPILPRPSQQTGSSSVNTFRPAYSSFSSGYGAYGNSFYGGYSPYSYGYNGLGYNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQRMLGLRRGSENEDLWAESEGTVACLGAEDRAATSAKSWPIFLFFAVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLTKGATVADSLDEQEAAFESVFVETNKVPVAPDSIGKDGEKQDL

Target ORF information:

RefSeq Version	NM_002618.3
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 13 (PEX13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002618.3

ORF Insert Sequence:

ATGGCGTCCC AGCCGCCACC TCCCCCCAAA CCCTGGGAGA CCCGCCGAAT TCCGGGAGCC 
GGACCGGGAC CAGGACCGGG CCCCACTTTC CAATCTGCTG ATTTGGGTCC TACTTTAATG 
ACAAGACCTG GACAACCAGC ACTTACCAGA GTGCCCCCAC CTATTCTTCC AAGGCCATCA 
CAGCAGACAG GAAGTAGCAG TGTGAACACT TTTAGACCTG CTTACAGTTC ATTTTCTTCT 
GGATATGGTG CCTATGGAAA TTCATTTTAT GGAGGCTATA GTCCTTATAG TTATGGATAT 
AATGGGCTGG GCTACAACCG CCTCCGTGTA GATGATCTTC CACCCAGTAG ATTTGTTCAG 
CAAGCTGAAG AAAGCAGCAG GGGTGCATTT CAGTCCATTG AAAGTATTGT GCATGCATTT 
GCCTCTGTCA GTATGATGAT GGATGCTACC TTTTCAGCTG TCTATAACAG TTTCAGGGCT 
GTATTGGATG TAGCAAATCA CTTTTCCCGA TTGAAAATAC ACTTTACAAA AGTGTTTTCA 
GCTTTTGCAT TGGTTAGGAC TATACGGTAT CTTTACAGAC GGCTACAGCG GATGTTAGGT 
TTAAGAAGAG GCTCTGAGAA TGAAGACCTC TGGGCAGAGA GTGAAGGAAC TGTGGCATGC 
CTTGGTGCTG AGGACCGAGC AGCTACCTCA GCAAAATCTT GGCCAATATT CTTGTTCTTT 
GCTGTTATCC TTGGTGGTCC TTACCTCATT TGGAAACTAT TGTCTACTCA CAGTGATGAA 
GTAACAGACA GCATCAACTG GGCAAGTGGT GAGGATGACC ATGTAGTTGC CAGAGCAGAA 
TATGATTTTG CTGCCGTATC TGAAGAAGAA ATTTCTTTCC GGGCTGGTGA TATGCTGAAC 
TTAGCTCTCA AAGAACAACA ACCCAAAGTG CGTGGTTGGC TTCTGGCTAG CCTTGATGGC 
CAAACAACAG GACTTATACC TGCGAATTAT GTCAAAATTC TTGGCAAAAG AAAAGGTAGG 
AAAACGGTGG AATCAAGTAA AGTTTCCAAG CAGCAACAAT CTTTTACCAA CCCAACACTA 
ACTAAAGGAG CCACGGTTGC TGATTCTTTG GATGAACAGG AAGCTGCCTT TGAATCTGTT 
TTTGTTGAAA CTAATAAGGT TCCAGTTGCA CCTGATTCCA TTGGGAAAGA TGGAGAAAAG 
CAAGATCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PEX13 ( NM_002618.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002609.1 Homo sapiens peroxisomal biogenesis factor 13 (PEX13), mRNA.

Price & Availability↑

CloneID	OHu26217
Clone ID Related Accession (Same CDS sequence)	NM_002618.3 , NM_002618.4
Accession Version	NM_002618.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	peroxisome biogenesis factor 13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB102467.1, AB022192.1, AC010733.8 and CN288682.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_002618.3. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.353160.1, SRR1660805.7239.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000295030.6/ ENSP00000295030.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGTCCC AGCCGCCACC TCCCCCCAAA CCCTGGGAGA CCCGCCGAAT TCCGGGAGCC 
GGACCGGGAC CAGGACCGGG CCCCACTTTC CAATCTGCTG ATTTGGGTCC TACTTTAATG 
ACAAGACCTG GACAACCAGC ACTTACCAGA GTGCCCCCAC CTATTCTTCC AAGGCCATCA 
CAGCAGACAG GAAGTAGCAG TGTGAACACT TTTAGACCTG CTTACAGTTC ATTTTCTTCT 
GGATATGGTG CCTATGGAAA TTCATTTTAT GGAGGCTATA GTCCTTATAG TTATGGATAT 
AATGGGCTGG GCTACAACCG CCTCCGTGTA GATGATCTTC CACCCAGTAG ATTTGTTCAG 
CAAGCTGAAG AAAGCAGCAG GGGTGCATTT CAGTCCATTG AAAGTATTGT GCATGCATTT 
GCCTCTGTCA GTATGATGAT GGATGCTACC TTTTCAGCTG TCTATAACAG TTTCAGGGCT 
GTATTGGATG TAGCAAATCA CTTTTCCCGA TTGAAAATAC ACTTTACAAA AGTGTTTTCA 
GCTTTTGCAT TGGTTAGGAC TATACGGTAT CTTTACAGAC GGCTACAGCG GATGTTAGGT 
TTAAGAAGAG GCTCTGAGAA TGAAGACCTC TGGGCAGAGA GTGAAGGAAC TGTGGCATGC 
CTTGGTGCTG AGGACCGAGC AGCTACCTCA GCAAAATCTT GGCCAATATT CTTGTTCTTT 
GCTGTTATCC TTGGTGGTCC TTACCTCATT TGGAAACTAT TGTCTACTCA CAGTGATGAA 
GTAACAGACA GCATCAACTG GGCAAGTGGT GAGGATGACC ATGTAGTTGC CAGAGCAGAA 
TATGATTTTG CTGCCGTATC TGAAGAAGAA ATTTCTTTCC GGGCTGGTGA TATGCTGAAC 
TTAGCTCTCA AAGAACAACA ACCCAAAGTG CGTGGTTGGC TTCTGGCTAG CCTTGATGGC 
CAAACAACAG GACTTATACC TGCGAATTAT GTCAAAATTC TTGGCAAAAG AAAAGGTAGG 
AAAACGGTGG AATCAAGTAA AGTTTCCAAG CAGCAACAAT CTTTTACCAA CCCAACACTA 
ACTAAAGGAG CCACGGTTGC TGATTCTTTG GATGAACAGG AAGCTGCCTT TGAATCTGTT 
TTTGTTGAAA CTAATAAGGT TCCAGTTGCA CCTGATTCCA TTGGGAAAGA TGGAGAAAAG 
CAAGATCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002609.1
CDS	41..1252
Translation	MASQPPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPALTRVPPPILPRPSQQTGSSSVNTFRPAYSSFSSGYGAYGNSFYGGYSPYSYGYNGLGYNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQRMLGLRRGSENEDLWAESEGTVACLGAEDRAATSAKSWPIFLFFAVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLTKGATVADSLDEQEAAFESVFVETNKVPVAPDSIGKDGEKQDL

Target ORF information:

RefSeq Version	NM_002618.4
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 13 (PEX13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002618.4

ORF Insert Sequence:

ATGGCGTCCC AGCCGCCACC TCCCCCCAAA CCCTGGGAGA CCCGCCGAAT TCCGGGAGCC 
GGACCGGGAC CAGGACCGGG CCCCACTTTC CAATCTGCTG ATTTGGGTCC TACTTTAATG 
ACAAGACCTG GACAACCAGC ACTTACCAGA GTGCCCCCAC CTATTCTTCC AAGGCCATCA 
CAGCAGACAG GAAGTAGCAG TGTGAACACT TTTAGACCTG CTTACAGTTC ATTTTCTTCT 
GGATATGGTG CCTATGGAAA TTCATTTTAT GGAGGCTATA GTCCTTATAG TTATGGATAT 
AATGGGCTGG GCTACAACCG CCTCCGTGTA GATGATCTTC CACCCAGTAG ATTTGTTCAG 
CAAGCTGAAG AAAGCAGCAG GGGTGCATTT CAGTCCATTG AAAGTATTGT GCATGCATTT 
GCCTCTGTCA GTATGATGAT GGATGCTACC TTTTCAGCTG TCTATAACAG TTTCAGGGCT 
GTATTGGATG TAGCAAATCA CTTTTCCCGA TTGAAAATAC ACTTTACAAA AGTGTTTTCA 
GCTTTTGCAT TGGTTAGGAC TATACGGTAT CTTTACAGAC GGCTACAGCG GATGTTAGGT 
TTAAGAAGAG GCTCTGAGAA TGAAGACCTC TGGGCAGAGA GTGAAGGAAC TGTGGCATGC 
CTTGGTGCTG AGGACCGAGC AGCTACCTCA GCAAAATCTT GGCCAATATT CTTGTTCTTT 
GCTGTTATCC TTGGTGGTCC TTACCTCATT TGGAAACTAT TGTCTACTCA CAGTGATGAA 
GTAACAGACA GCATCAACTG GGCAAGTGGT GAGGATGACC ATGTAGTTGC CAGAGCAGAA 
TATGATTTTG CTGCCGTATC TGAAGAAGAA ATTTCTTTCC GGGCTGGTGA TATGCTGAAC 
TTAGCTCTCA AAGAACAACA ACCCAAAGTG CGTGGTTGGC TTCTGGCTAG CCTTGATGGC 
CAAACAACAG GACTTATACC TGCGAATTAT GTCAAAATTC TTGGCAAAAG AAAAGGTAGG 
AAAACGGTGG AATCAAGTAA AGTTTCCAAG CAGCAACAAT CTTTTACCAA CCCAACACTA 
ACTAAAGGAG CCACGGTTGC TGATTCTTTG GATGAACAGG AAGCTGCCTT TGAATCTGTT 
TTTGTTGAAA CTAATAAGGT TCCAGTTGCA CCTGATTCCA TTGGGAAAGA TGGAGAAAAG 
CAAGATCTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The peroxisomal matrix protein translocon is a large cavity-forming protein assembly into which PEX5 protein enters to release its cargo.
The Journal of biological chemistry292(37)15287-15300(2017 09)
Dias AF,Rodrigues TA,Pedrosa AG,Barros-Barbosa A,Francisco T,Azevedo JE

Peroxisomal protein PEX13 functions in selective autophagy.
EMBO reports18(1)48-60(2017 01)
Lee MY,Sumpter R Jr,Zou Z,Sirasanagandla S,Wei Y,Mishra P,Rosewich H,Crane DI,Levine B

Functional analysis of PEX13 mutation in a Zellweger syndrome spectrum patient reveals novel homooligomerization of PEX13 and its role in human peroxisome biogenesis.
Human molecular genetics22(19)3844-57(2013 Oct)
Krause C,Rosewich H,Woehler A,G?rtner J

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
PLoS genetics8(3)e1002559(2012)
Kenny EE,Pe'er I,Karban A,Ozelius L,Mitchell AA,Ng SM,Erazo M,Ostrer H,Abraham C,Abreu MT,Atzmon G,Barzilai N,Brant SR,Bressman S,Burns ER,Chowers Y,Clark LN,Darvasi A,Doheny D,Duerr RH,Eliakim R,Giladi N,Gregersen PK,Hakonarson H,Jones MR,Marder K,McGovern DP,Mulle J,Orr-Urtreger A,Proctor DD,Pulver A,Rotter JI,Silverberg MS,Ullman T,Warren ST,Waterman M,Zhang W,Bergman A,Mayer L,Katz S,Desnick RJ,Cho JH,Peter I

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PEX13 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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