RTEL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RTEL1
Entrez Gene ID	51750
Full Name	regulator of telomere elongation helicase 1
Synonyms	C20orf41,DKCA4,DKCB5,NHL,PFBMFT3,RTEL
General protein information	Preferred Names regulator of telomere elongation helicase 1 Names regulator of telomere elongation helicase 1 regulator of telomere length
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013].
Disorder MIM:	608833
Disorder Html:	Dyskeratosis congenita, autosomal recessive 5, 615190 (3); Dyskeratosis congenita, autosomal dominant 4, 615190 (3); Pulmonary fibrosis and/or bone marrow failure, telomere-related, 3, 616373 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_032957.4	NP_116575.3	regulator of telomere elongation helicase 1 isoform 2
NM_032957.5	NP_116575.3	regulator of telomere elongation helicase 1 isoform 2
NM_016434.4	NP_057518.1	regulator of telomere elongation helicase 1 isoform 1
NM_001283009.1	NP_001269938.1	regulator of telomere elongation helicase 1 isoform 3
NM_016434.3	NP_057518.1	regulator of telomere elongation helicase 1 isoform 1
NM_001283010.1	NP_001269939.1	regulator of telomere elongation helicase 1 isoform 4
NM_001283009.2	NP_001269938.1	regulator of telomere elongation helicase 1 isoform 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Rtel1	NP_001001882.3
Drosophila melanogaster (fruit fly)	CG4078	NP_572254.1
Arabidopsis thaliana (thale cress)	AT1G79950	NP_178113.3
Oryza sativa (rice)	Os01g0592900	NP_001043456.2
Gallus gallus (chicken)	RTEL1	XP_004947187.1
Danio rerio (zebrafish)	rtel1	NP_001013328.2
Anopheles gambiae (African malaria mosquito)	RTEL1_ANOGA	XP_311162.5
	LOC719519	XP_001113864.2
Canis lupus familiaris (dog)	RTEL1	XP_005635362.1
Bos taurus (cattle)	RTEL1	NP_001091044.1
Caenorhabditis elegans (roundworm)	rtel-1	NP_492769.1
Homo sapiens (human)	RTEL1	NP_001269938.1
Pan troglodytes (chimpanzee)	RTEL1	XP_003953846.1
Rattus norvegicus (Norway rat)	Rtel1	NP_001178786.1

Gene Ontology
Bibliography

Related articles in PubMed

Heterozygous
Marsh JCW, Gutierrez-Rodrigues F, Cooper J, Jiang J, Gandhi S, Kajigaya S, Feng X, Ibanez MDPF, Donaires FS, Lopes da Silva JP, Li Z, Das S, Ibanez M, Smith AE, Lea N, Best S, Ireland R, Kulasekararaj AG, McLornan DP, Pagliuca A, Callebaut I, Young NS, Calado RT, Townsley DM, Mufti GJ
Blood advances2(1)36-48(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The allele "G" of rs6089953 and rs6010621 and the allele "A" of rs2297441 were associated with decreased risk of High altitude pulmonary edema, haplotype "GG, GT, AT" of rs6089953-rs6010621 were detected significantly associated with High altitude pulmonary edema risk in the Chinese population.
Title: Association between regulator of telomere elongation helicase1 (RTEL1) gene and HAPE risk: A case-control study.

SNPs in the RTEL1 are associated with COPD in a Chinese Han population. It is possible that these variants are COPD risk factors.
Title: Association between

promoter methylated in 51.4% of lung cancer patients and in 8.8% of healthy individuals
Title: Analysis of RTEL1 and PCDHGB6 promoter methylation in circulating-free DNA of lung cancer patients using liquid biopsy: A pilot study.

This meta-analysis demonstrates that the RTEL1 rs2297440 polymorphism plays a moderate, but significant role in the risk of glioma.
Title: The role of the RTEL1 rs2297440 polymorphism in the risk of glioma development: a meta-analysis.

Genetic risk variants in the RTEL1 gene is associated with somatic biomarkers in glioma.
Title: Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma.

The following RTEL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RTEL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13841	NM_016434.4 Latest version!	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$614.50-$860.30 $1229.00
OHu14298	NM_001283009.2 Latest version!	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$459.50-$643.30 $919.00
OHu14345	NM_001283010.1 Latest version!	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu19254	NM_032957.5 Latest version!	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$654.50-$916.30 $1309.00
View Old Accession Versions >>
OHu19254	NM_032957.4	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$654.50-$916.30 $1309.00
OHu13841	NM_016434.3	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$614.50-$860.30 $1229.00
OHu14298	NM_001283009.1	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$459.50-$643.30 $919.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RTEL1 ( NM_016434.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057518.1 Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13841
Clone ID Related Accession (Same CDS sequence)	NM_016434.4 , NM_016434.3
Accession Version	NM_016434.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	regulator of telomere elongation helicase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF217795.1 and AL353715.21. This sequence is a reference standard in the RefSeqGene project. On Sep 3, 2019 this sequence version replaced NM_016434.3. Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region that results in a translational frameshift, compared to variant 3. The resulting protein (isoform 1) has a distinct C-terminus and is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF217795.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057518.1
CDS	326..3985
Translation	MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGL

Target ORF information:

RefSeq Version	NM_016434.4
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016434.4

ORF Insert Sequence:

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RTEL1 ( NM_016434.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057518.1 Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13841
Clone ID Related Accession (Same CDS sequence)	NM_016434.4 , NM_016434.3
Accession Version	NM_016434.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-13
Organism	Homo sapiens(human)
Product	regulator of telomere elongation helicase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF217795.1 and AW005229.1. This sequence is a reference standard in the RefSeqGene project. On Feb 17, 2011 this sequence version replaced NM_016434.2. Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region that results in a translational frameshift, compared to variant 3. The resulting protein (isoform 1) has a distinct C-terminus and is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF217795.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057518.1
CDS	828..4487
Translation	MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGL

Target ORF information:

RefSeq Version	NM_016434.3
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016434.3

ORF Insert Sequence:

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGCCTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RTEL1 ( NM_001283009.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269938.1 Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3, mRNA.

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CloneID	OHu14298
Clone ID Related Accession (Same CDS sequence)	NM_001283009.1 , NM_001283009.2
Accession Version	NM_001283009.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-13
Organism	Homo sapiens(human)
Product	regulator of telomere elongation helicase 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF217795.1, JX119186.1 and AW005229.1. This sequence is a reference standard in the RefSeqGene project. On Sep 25, 2013 this sequence version replaced XM_005260207.1. Transcript Variant: This variant (3) represents the longest transcript and encodes the longest protein (isoform 3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.267126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGTGAGCCT 
CATGGGAGAG ACATCGCTGG GCAGCAGGCC ACGGGAGCTC CGGGCGGGCC CCTCTCAGCA 
GGCTGTGTGT GCCAGGGCTG TGGGGCAGAG GACGTGGTGC CCTTCCAGTG CCCTGCCTGT 
GACTTCCAGC GCTGCCAAGC CTGCTGGCAA CGGCACCTTC AGGCCTCTAG GATGTGCCCA 
GCCTGCCACA CCGCCTCCAG GAAGCAGAGC GTCATGCAGG TCTTCTGGCC AGAGCCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269938.1
CDS	828..4730
Translation	MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPQ

Target ORF information:

RefSeq Version	NM_001283009.1
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001283009.1

ORF Insert Sequence:

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGTGAGCCT 
CATGGGAGAG ACATCGCTGG GCAGCAGGCC ACGGGAGCTC CGGGCGGGCC CCTCTCAGCA 
GGCTGTGTGT GCCAGGGCTG TGGGGCAGAG GACGTGGTGC CCTTCCAGTG CCCTGCCTGT 
GACTTCCAGC GCTGCCAAGC CTGCTGGCAA CGGCACCTTC AGGCCTCTAG GATGTGCCCA 
GCCTGCCACA CCGCCTCCAG GAAGCAGAGC GTCATGCAGG TCTTCTGGCC AGAGCCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RTEL1 ( NM_001283009.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269938.1 Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu14298
Clone ID Related Accession (Same CDS sequence)	NM_001283009.1 , NM_001283009.2
Accession Version	NM_001283009.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	regulator of telomere elongation helicase 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF217795.1, JX119186.1 and AW005229.1. This sequence is a reference standard in the RefSeqGene project. On Sep 3, 2019 this sequence version replaced NM_001283009.1. Transcript Variant: This variant (3) represents the longest transcript and encodes the longest protein (isoform 3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.267126.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGTGAGCCT 
CATGGGAGAG ACATCGCTGG GCAGCAGGCC ACGGGAGCTC CGGGCGGGCC CCTCTCAGCA 
GGCTGTGTGT GCCAGGGCTG TGGGGCAGAG GACGTGGTGC CCTTCCAGTG CCCTGCCTGT 
GACTTCCAGC GCTGCCAAGC CTGCTGGCAA CGGCACCTTC AGGCCTCTAG GATGTGCCCA 
GCCTGCCACA CCGCCTCCAG GAAGCAGAGC GTCATGCAGG TCTTCTGGCC AGAGCCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269938.1
CDS	326..4228
Translation	MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPQ

Target ORF information:

RefSeq Version	NM_001283009.2
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001283009.2

ORF Insert Sequence:

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGGCCTA AGGTGTGTGT GCTGGGCTCC 
CGGGAGCAGC TGTGCATCCA TCCTGAGGTG AAGAAACAAG AGAGTAACCA TCTACAGATC 
CACTTGTGCC GTAAGAAGGT GGCAAGTCGC TCCTGTCATT TCTACAACAA CGTAGAAGAA 
AAAAGCCTGG AGCAGGAGCT GGCCAGCCCC ATCCTGGACA TTGAGGACTT GGTCAAGAGC 
GGAAGCAAGC ACAGGGTGTG CCCTTACTAC CTGTCCCGGA ACCTGAAGCA GCAAGCCGAC 
ATCATATTCA TGCCGTACAA TTACTTGTTG GATGCCAAGA GCCGCAGAGC ACACAACATT 
GACCTGAAGG GGACAGTCGT GATCTTTGAC GAAGCTCACA ACGTGGAGAA GATGTGTGAA 
GAATCGGCAT CCTTTGACCT GACTCCCCAT GACCTGGCTT CAGGACTGGA CGTCATAGAC 
CAGGTGCTGG AGGAGCAGAC CAAGGCAGCG CAGCAGGGTG AGCCCCACCC GGAGTTCAGC 
GCGGACTCCC CCAGCCCAGG GCTGAACATG GAGCTGGAAG ACATTGCAAA GCTGAAGATG 
ATCCTGCTGC GCCTGGAGGG GGCCATCGAT GCTGTTGAGC TGCCTGGAGA CGACAGCGGT 
GTCACCAAGC CAGGGAGCTA CATCTTTGAG CTGTTTGCTG AAGCCCAGAT CACGTTTCAG 
ACCAAGGGCT GCATCCTGGA CTCGCTGGAC CAGATCATCC AGCACCTGGC AGGACGTGCT 
GGAGTGTTCA CCAACACGGC CGGACTGCAG AAGCTGGCGG ACATTATCCA GATTGTGTTC 
AGTGTGGACC CCTCCGAGGG CAGCCCTGGT TCCCCAGCAG GGCTGGGGGC CTTACAGTCC 
TATAAGGTGC ACATCCATCC TGATGCTGGT CACCGGAGGA CGGCTCAGCG GTCTGATGCC 
TGGAGCACCA CTGCAGCCAG AAAGCGAGGG AAGGTGCTGA GCTACTGGTG CTTCAGTCCC 
GGCCACAGCA TGCACGAGCT GGTCCGCCAG GGCGTCCGCT CCCTCATCCT TACCAGCGGC 
ACGCTGGCCC CGGTGTCCTC CTTTGCTCTG GAGATGCAGA TCCCTTTCCC AGTCTGCCTG 
GAGAACCCAC ACATCATCGA CAAGCACCAG ATCTGGGTGG GGGTCGTCCC CAGAGGCCCC 
GATGGAGCCC AGTTGAGCTC CGCGTTTGAC AGACGGTTTT CCGAGGAGTG CTTATCCTCC 
CTGGGGAAGG CTCTGGGCAA CATCGCCCGC GTGGTGCCCT ATGGGCTCCT GATCTTCTTC 
CCTTCCTATC CTGTCATGGA GAAGAGCCTG GAGTTCTGGC GGGCCCGCGA CTTGGCCAGG 
AAGATGGAGG CGCTGAAGCC GCTGTTTGTG GAGCCCAGGA GCAAAGGCAG CTTCTCCGAG 
ACCATCAGTG CTTACTATGC AAGGGTTGCC GCCCCTGGGT CCACCGGCGC CACCTTCCTG 
GCGGTCTGCC GGGGCAAGGC CAGCGAGGGG CTGGACTTCT CAGACACGAA TGGCCGTGGT 
GTGATTGTCA CGGGCCTCCC GTACCCCCCA CGCATGGACC CCCGGGTTGT CCTCAAGATG 
CAGTTCCTGG ATGAGATGAA GGGCCAGGGT GGGGCTGGGG GCCAGTTCCT CTCTGGGCAG 
GAGTGGTACC GGCAGCAGGC GTCCAGGGCT GTGAACCAGG CCATCGGGCG AGTGATCCGG 
CACCGCCAGG ACTACGGAGC TGTCTTCCTC TGTGACCACA GGTTCGCCTT TGCCGACGCA 
AGAGCCCAAC TGCCCTCCTG GGTGCGTCCC CACGTCAGGG TGTATGACAA CTTTGGCCAT 
GTCATCCGAG ACGTGGCCCA GTTCTTCCGT GTTGCCGAGC GAACTATGCC AGCGCCGGCC 
CCCCGGGCTA CAGCACCCAG TGTGCGTGGA GAAGATGCTG TCAGCGAGGC CAAGTCGCCT 
GGCCCCTTCT TCTCCACCAG GAAAGCTAAG AGTCTGGACC TGCATGTCCC CAGCCTGAAG 
CAGAGGTCCT CAGGGTCACC AGCTGCCGGG GACCCCGAGA GTAGCCTGTG TGTGGAGTAT 
GAGCAGGAGC CAGTTCCTGC CCGGCAGAGG CCCAGGGGGC TGCTGGCCGC CCTGGAGCAC 
AGCGAACAGC GGGCGGGGAG CCCTGGCGAG GAGCAGGCCC ACAGCTGCTC CACCCTGTCC 
CTCCTGTCTG AGAAGAGGCC GGCAGAAGAA CCGCGAGGAG GGAGGAAGAA GATCCGGCTG 
GTCAGCCACC CGGAGGAGCC CGTGGCTGGT GCACAGACGG ACAGGGCCAA GCTCTTCATG 
GTGGCCGTGA AGCAGGAGTT GAGCCAAGCC AACTTTGCCA CCTTCACCCA GGCCCTGCAG 
GACTACAAGG GTTCCGATGA CTTCGCCGCC CTGGCCGCCT GTCTCGGCCC CCTCTTTGCT 
GAGGACCCCA AGAAGCACAA CCTGCTCCAA GGCTTCTACC AGTTTGTGCG GCCCCACCAT 
AAGCAGCAGT TTGAGGAGGT CTGTATCCAG CTGACAGGAC GAGGCTGTGG CTATCGGCCT 
GAGCACAGCA TTCCCCGAAG GCAGCGGGCA CAGCCGGTCC TGGACCCCAC TGGAAGAACG 
GCGCCGGATC CCAAGCTGAC CGTGTCCACG GCTGCAGCCC AGCAGCTGGA CCCCCAAGAG 
CACCTGAACC AGGGCAGGCC CCACCTGTCG CCCAGGCCAC CCCCAACAGG AGACCCTGGC 
AGCCAACCAC AGTGGGGGTC TGGAGTGCCC AGAGCAGGGA AGCAGGGCCA GCACGCCGTG 
AGCGCCTACC TGGCTGATGC CCGCAGGGCC CTGGGGTCCG CGGGCTGTAG CCAACTCTTG 
GCAGCGCTGA CAGCCTATAA GCAAGACGAC GACCTCGACA AGGTGCTGGC TGTGTTGGCC 
GCCCTGACCA CTGCAAAGCC AGAGGACTTC CCCCTGCTGC ACAGGTTCAG CATGTTTGTG 
CGTCCACACC ACAAGCAGCG CTTCTCACAG ACGTGCACAG ACCTGACCGG CCGGCCCTAC 
CCGGGCATGG AGCCACCGGG ACCCCAGGAG GAGAGGCTTG CCGTGCCTCC TGTGCTTACC 
CACAGGGCTC CCCAACCAGG CCCCTCACGG TCCGAGAAGA CCGGGAAGAC CCAGAGCAAG 
ATCTCGTCCT TCCTTAGACA GAGGCCAGCA GGGACTGTGG GGGCGGGCGG TGAGGATGCA 
GGTCCCAGCC AGTCCTCAGG ACCTCCCCAC GGGCCTGCAG CATCTGAGTG GGGTGAGCCT 
CATGGGAGAG ACATCGCTGG GCAGCAGGCC ACGGGAGCTC CGGGCGGGCC CCTCTCAGCA 
GGCTGTGTGT GCCAGGGCTG TGGGGCAGAG GACGTGGTGC CCTTCCAGTG CCCTGCCTGT 
GACTTCCAGC GCTGCCAAGC CTGCTGGCAA CGGCACCTTC AGGCCTCTAG GATGTGCCCA 
GCCTGCCACA CCGCCTCCAG GAAGCAGAGC GTCATGCAGG TCTTCTGGCC AGAGCCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RTEL1 ( NM_001283010.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269939.1 Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu14345
Clone ID Related Accession (Same CDS sequence)	NM_001283010.1
Accession Version	NM_001283010.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2991bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	regulator of telomere elongation helicase 1 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF217795.1, AK304798.1 and AW005229.1. Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences include translation initiation at a downstream AUG and a translational frameshift. The resulting protein (isoform 4) has a shorter N-terminus and distinct C-terminus, compared to isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304798.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGTACA ATTACTTGTT GGATGCCAAG AGCCGCAGAG CACACAACAT TGACCTGAAG 
GGGACAGTCG TGATCTTTGA CGAAGCTCAC AACGTGGAGA AGATGTGTGA AGAATCGGCA 
TCCTTTGACC TGACTCCCCA TGACCTGGCT TCAGGACTGG ACGTCATAGA CCAGGTGCTG 
GAGGAGCAGA CCAAGGCAGC GCAGCAGGGT GAGCCCCACC CGGAGTTCAG CGCGGACTCC 
CCCAGCCCAG GGCTGAACAT GGAGCTGGAA GACATTGCAA AGCTGAAGAT GATCCTGCTG 
CGCCTGGAGG GGGCCATCGA TGCTGTTGAG CTGCCTGGAG ACGACAGCGG TGTCACCAAG 
CCAGGGAGCT ACATCTTTGA GCTGTTTGCT GAAGCCCAGA TCACGTTTCA GACCAAGGGC 
TGCATCCTGG ACTCGCTGGA CCAGATCATC CAGCACCTGG CAGGACGTGC TGGAGTGTTC 
ACCAACACGG CCGGACTGCA GAAGCTGGCG GACATTATCC AGATTGTGTT CAGTGTGGAC 
CCCTCCGAGG GCAGCCCTGG TTCCCCAGCA GGGCTGGGGG CCTTACAGTC CTATAAGGTG 
CACATCCATC CTGATGCTGG TCACCGGAGG ACGGCTCAGC GGTCTGATGC CTGGAGCACC 
ACTGCAGCCA GAAAGCGAGG GAAGGTGCTG AGCTACTGGT GCTTCAGTCC CGGCCACAGC 
ATGCACGAGC TGGTCCGCCA GGGCGTCCGC TCCCTCATCC TTACCAGCGG CACGCTGGCC 
CCGGTGTCCT CCTTTGCTCT GGAGATGCAG ATCCCTTTCC CAGTCTGCCT GGAGAACCCA 
CACATCATCG ACAAGCACCA GATCTGGGTG GGGGTCGTCC CCAGAGGCCC CGATGGAGCC 
CAGTTGAGCT CCGCGTTTGA CAGACGGTTT TCCGAGGAGT GCTTATCCTC CCTGGGGAAG 
GCTCTGGGCA ACATCGCCCG CGTGGTGCCC TATGGGCTCC TGATCTTCTT CCCTTCCTAT 
CCTGTCATGG AGAAGAGCCT GGAGTTCTGG CGGGCCCGCG ACTTGGCCAG GAAGATGGAG 
GCGCTGAAGC CGCTGTTTGT GGAGCCCAGG AGCAAAGGCA GCTTCTCCGA GACCATCAGT 
GCTTACTATG CAAGGGTTGC CGCCCCTGGG TCCACCGGCG CCACCTTCCT GGCGGTCTGC 
CGGGGCAAGG CCAGCGAGGG GCTGGACTTC TCAGACACGA ATGGCCGTGG TGTGATTGTC 
ACGGGCCTCC CGTACCCCCC ACGCATGGAC CCCCGGGTTG TCCTCAAGAT GCAGTTCCTG 
GATGAGATGA AGGGCCAGGG TGGGGCTGGG GGCCAGTTCC TCTCTGGGCA GGAGTGGTAC 
CGGCAGCAGG CGTCCAGGGC TGTGAACCAG GCCATCGGGC GAGTGATCCG GCACCGCCAG 
GACTACGGAG CTGTCTTCCT CTGTGACCAC AGGTTCGCCT TTGCCGACGC AAGAGCCCAA 
CTGCCCTCCT GGGTGCGTCC CCACGTCAGG GTGTATGACA ACTTTGGCCA TGTCATCCGA 
GACGTGGCCC AGTTCTTCCG TGTTGCCGAG CGAACTATGC CAGCGCCGGC CCCCCGGGCT 
ACAGCACCCA GTGTGCGTGG AGAAGATGCT GTCAGCGAGG CCAAGTCGCC TGGCCCCTTC 
TTCTCCACCA GGAAAGCTAA GAGTCTGGAC CTGCATGTCC CCAGCCTGAA GCAGAGGTCC 
TCAGGGTCAC CAGCTGCCGG GGACCCCGAG AGTAGCCTGT GTGTGGAGTA TGAGCAGGAG 
CCAGTTCCTG CCCGGCAGAG GCCCAGGGGG CTGCTGGCCG CCCTGGAGCA CAGCGAACAG 
CGGGCGGGGA GCCCTGGCGA GGAGCAGGCC CACAGCTGCT CCACCCTGTC CCTCCTGTCT 
GAGAAGAGGC CGGCAGAAGA ACCGCGAGGA GGGAGGAAGA AGATCCGGCT GGTCAGCCAC 
CCGGAGGAGC CCGTGGCTGG TGCACAGACG GACAGGGCCA AGCTCTTCAT GGTGGCCGTG 
AAGCAGGAGT TGAGCCAAGC CAACTTTGCC ACCTTCACCC AGGCCCTGCA GGACTACAAG 
GGTTCCGATG ACTTCGCCGC CCTGGCCGCC TGTCTCGGCC CCCTCTTTGC TGAGGACCCC 
AAGAAGCACA ACCTGCTCCA AGGCTTCTAC CAGTTTGTGC GGCCCCACCA TAAGCAGCAG 
TTTGAGGAGG TCTGTATCCA GCTGACAGGA CGAGGCTGTG GCTATCGGCC TGAGCACAGC 
ATTCCCCGAA GGCAGCGGGC ACAGCCGGTC CTGGACCCCA CTGGAAGAAC GGCGCCGGAT 
CCCAAGCTGA CCGTGTCCAC GGCTGCAGCC CAGCAGCTGG ACCCCCAAGA GCACCTGAAC 
CAGGGCAGGC CCCACCTGTC GCCCAGGCCA CCCCCAACAG GAGACCCTGG CAGCCAACCA 
CAGTGGGGGT CTGGAGTGCC CAGAGCAGGG AAGCAGGGCC AGCACGCCGT GAGCGCCTAC 
CTGGCTGATG CCCGCAGGGC CCTGGGGTCC GCGGGCTGTA GCCAACTCTT GGCAGCGCTG 
ACAGCCTATA AGCAAGACGA CGACCTCGAC AAGGTGCTGG CTGTGTTGGC CGCCCTGACC 
ACTGCAAAGC CAGAGGACTT CCCCCTGCTG CACAGGTTCA GCATGTTTGT GCGTCCACAC 
CACAAGCAGC GCTTCTCACA GACGTGCACA GACCTGACCG GCCGGCCCTA CCCGGGCATG 
GAGCCACCGG GACCCCAGGA GGAGAGGCTT GCCGTGCCTC CTGTGCTTAC CCACAGGGCT 
CCCCAACCAG GCCCCTCACG GTCCGAGAAG ACCGGGAAGA CCCAGAGCAA GATCTCGTCC 
TTCCTTAGAC AGAGGCCAGC AGGGACTGTG GGGGCGGGCG GTGAGGATGC AGGTCCCAGC 
CAGTCCTCAG GACCTCCCCA CGGGCCTGCA GCATCTGAGT GGGGCCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269939.1
CDS	1218..4208
Translation	MPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGL

Target ORF information:

RefSeq Version	NM_001283010.1
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001283010.1

ORF Insert Sequence:

ATGCCGTACA ATTACTTGTT GGATGCCAAG AGCCGCAGAG CACACAACAT TGACCTGAAG 
GGGACAGTCG TGATCTTTGA CGAAGCTCAC AACGTGGAGA AGATGTGTGA AGAATCGGCA 
TCCTTTGACC TGACTCCCCA TGACCTGGCT TCAGGACTGG ACGTCATAGA CCAGGTGCTG 
GAGGAGCAGA CCAAGGCAGC GCAGCAGGGT GAGCCCCACC CGGAGTTCAG CGCGGACTCC 
CCCAGCCCAG GGCTGAACAT GGAGCTGGAA GACATTGCAA AGCTGAAGAT GATCCTGCTG 
CGCCTGGAGG GGGCCATCGA TGCTGTTGAG CTGCCTGGAG ACGACAGCGG TGTCACCAAG 
CCAGGGAGCT ACATCTTTGA GCTGTTTGCT GAAGCCCAGA TCACGTTTCA GACCAAGGGC 
TGCATCCTGG ACTCGCTGGA CCAGATCATC CAGCACCTGG CAGGACGTGC TGGAGTGTTC 
ACCAACACGG CCGGACTGCA GAAGCTGGCG GACATTATCC AGATTGTGTT CAGTGTGGAC 
CCCTCCGAGG GCAGCCCTGG TTCCCCAGCA GGGCTGGGGG CCTTACAGTC CTATAAGGTG 
CACATCCATC CTGATGCTGG TCACCGGAGG ACGGCTCAGC GGTCTGATGC CTGGAGCACC 
ACTGCAGCCA GAAAGCGAGG GAAGGTGCTG AGCTACTGGT GCTTCAGTCC CGGCCACAGC 
ATGCACGAGC TGGTCCGCCA GGGCGTCCGC TCCCTCATCC TTACCAGCGG CACGCTGGCC 
CCGGTGTCCT CCTTTGCTCT GGAGATGCAG ATCCCTTTCC CAGTCTGCCT GGAGAACCCA 
CACATCATCG ACAAGCACCA GATCTGGGTG GGGGTCGTCC CCAGAGGCCC CGATGGAGCC 
CAGTTGAGCT CCGCGTTTGA CAGACGGTTT TCCGAGGAGT GCTTATCCTC CCTGGGGAAG 
GCTCTGGGCA ACATCGCCCG CGTGGTGCCC TATGGGCTCC TGATCTTCTT CCCTTCCTAT 
CCTGTCATGG AGAAGAGCCT GGAGTTCTGG CGGGCCCGCG ACTTGGCCAG GAAGATGGAG 
GCGCTGAAGC CGCTGTTTGT GGAGCCCAGG AGCAAAGGCA GCTTCTCCGA GACCATCAGT 
GCTTACTATG CAAGGGTTGC CGCCCCTGGG TCCACCGGCG CCACCTTCCT GGCGGTCTGC 
CGGGGCAAGG CCAGCGAGGG GCTGGACTTC TCAGACACGA ATGGCCGTGG TGTGATTGTC 
ACGGGCCTCC CGTACCCCCC ACGCATGGAC CCCCGGGTTG TCCTCAAGAT GCAGTTCCTG 
GATGAGATGA AGGGCCAGGG TGGGGCTGGG GGCCAGTTCC TCTCTGGGCA GGAGTGGTAC 
CGGCAGCAGG CGTCCAGGGC TGTGAACCAG GCCATCGGGC GAGTGATCCG GCACCGCCAG 
GACTACGGAG CTGTCTTCCT CTGTGACCAC AGGTTCGCCT TTGCCGACGC AAGAGCCCAA 
CTGCCCTCCT GGGTGCGTCC CCACGTCAGG GTGTATGACA ACTTTGGCCA TGTCATCCGA 
GACGTGGCCC AGTTCTTCCG TGTTGCCGAG CGAACTATGC CAGCGCCGGC CCCCCGGGCT 
ACAGCACCCA GTGTGCGTGG AGAAGATGCT GTCAGCGAGG CCAAGTCGCC TGGCCCCTTC 
TTCTCCACCA GGAAAGCTAA GAGTCTGGAC CTGCATGTCC CCAGCCTGAA GCAGAGGTCC 
TCAGGGTCAC CAGCTGCCGG GGACCCCGAG AGTAGCCTGT GTGTGGAGTA TGAGCAGGAG 
CCAGTTCCTG CCCGGCAGAG GCCCAGGGGG CTGCTGGCCG CCCTGGAGCA CAGCGAACAG 
CGGGCGGGGA GCCCTGGCGA GGAGCAGGCC CACAGCTGCT CCACCCTGTC CCTCCTGTCT 
GAGAAGAGGC CGGCAGAAGA ACCGCGAGGA GGGAGGAAGA AGATCCGGCT GGTCAGCCAC 
CCGGAGGAGC CCGTGGCTGG TGCACAGACG GACAGGGCCA AGCTCTTCAT GGTGGCCGTG 
AAGCAGGAGT TGAGCCAAGC CAACTTTGCC ACCTTCACCC AGGCCCTGCA GGACTACAAG 
GGTTCCGATG ACTTCGCCGC CCTGGCCGCC TGTCTCGGCC CCCTCTTTGC TGAGGACCCC 
AAGAAGCACA ACCTGCTCCA AGGCTTCTAC CAGTTTGTGC GGCCCCACCA TAAGCAGCAG 
TTTGAGGAGG TCTGTATCCA GCTGACAGGA CGAGGCTGTG GCTATCGGCC TGAGCACAGC 
ATTCCCCGAA GGCAGCGGGC ACAGCCGGTC CTGGACCCCA CTGGAAGAAC GGCGCCGGAT 
CCCAAGCTGA CCGTGTCCAC GGCTGCAGCC CAGCAGCTGG ACCCCCAAGA GCACCTGAAC 
CAGGGCAGGC CCCACCTGTC GCCCAGGCCA CCCCCAACAG GAGACCCTGG CAGCCAACCA 
CAGTGGGGGT CTGGAGTGCC CAGAGCAGGG AAGCAGGGCC AGCACGCCGT GAGCGCCTAC 
CTGGCTGATG CCCGCAGGGC CCTGGGGTCC GCGGGCTGTA GCCAACTCTT GGCAGCGCTG 
ACAGCCTATA AGCAAGACGA CGACCTCGAC AAGGTGCTGG CTGTGTTGGC CGCCCTGACC 
ACTGCAAAGC CAGAGGACTT CCCCCTGCTG CACAGGTTCA GCATGTTTGT GCGTCCACAC 
CACAAGCAGC GCTTCTCACA GACGTGCACA GACCTGACCG GCCGGCCCTA CCCGGGCATG 
GAGCCACCGG GACCCCAGGA GGAGAGGCTT GCCGTGCCTC CTGTGCTTAC CCACAGGGCT 
CCCCAACCAG GCCCCTCACG GTCCGAGAAG ACCGGGAAGA CCCAGAGCAA GATCTCGTCC 
TTCCTTAGAC AGAGGCCAGC AGGGACTGTG GGGGCGGGCG GTGAGGATGC AGGTCCCAGC 
CAGTCCTCAG GACCTCCCCA CGGGCCTGCA GCATCTGAGT GGGGCCTCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RTEL1 ( NM_032957.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_116575.3 Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mRNA.

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CloneID	OHu19254
Clone ID Related Accession (Same CDS sequence)	NM_032957.4 , NM_032957.5
Accession Version	NM_032957.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-13
Organism	Homo sapiens(human)
Product	regulator of telomere elongation helicase 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF217795.1, AK302508.1 and AW005229.1. This sequence is a reference standard in the RefSeqGene project. On Feb 17, 2011 this sequence version replaced NM_032957.3. Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 3, one of which results in a translational frameshift. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302508.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGCTCAC GCTGCAGGGC CACGCTGTGG 
GTGTTGGAGA CAGCTCCTCC TCGACCCACG GTGCTCTCTC CCACCAGGCC TAAGGTGTGT 
GTGCTGGGCT CCCGGGAGCA GCTGTGCATC CATCCTGAGG TGAAGAAACA AGAGAGTAAC 
CATCTACAGA TCCACTTGTG CCGTAAGAAG GTGGCAAGTC GCTCCTGTCA TTTCTACAAC 
AACGTAGAAG AAAAAAGCCT GGAGCAGGAG CTGGCCAGCC CCATCCTGGA CATTGAGGAC 
TTGGTCAAGA GCGGAAGCAA GCACAGGGTG TGCCCTTACT ACCTGTCCCG GAACCTGAAG 
CAGCAAGCCG ACATCATATT CATGCCGTAC AATTACTTGT TGGATGCCAA GAGCCGCAGA 
GCACACAACA TTGACCTGAA GGGGACAGTC GTGATCTTTG ACGAAGCTCA CAACGTGGAG 
AAGATGTGTG AAGAATCGGC ATCCTTTGAC CTGACTCCCC ATGACCTGGC TTCAGGACTG 
GACGTCATAG ACCAGGTGCT GGAGGAGCAG ACCAAGGCAG CGCAGCAGGG TGAGCCCCAC 
CCGGAGTTCA GCGCGGACTC CCCCAGCCCA GGGCTGAACA TGGAGCTGGA AGACATTGCA 
AAGCTGAAGA TGATCCTGCT GCGCCTGGAG GGGGCCATCG ATGCTGTTGA GCTGCCTGGA 
GACGACAGCG GTGTCACCAA GCCAGGGAGC TACATCTTTG AGCTGTTTGC TGAAGCCCAG 
ATCACGTTTC AGACCAAGGG CTGCATCCTG GACTCGCTGG ACCAGATCAT CCAGCACCTG 
GCAGGACGTG CTGGAGTGTT CACCAACACG GCCGGACTGC AGAAGCTGGC GGACATTATC 
CAGATTGTGT TCAGTGTGGA CCCCTCCGAG GGCAGCCCTG GTTCCCCAGC AGGGCTGGGG 
GCCTTACAGT CCTATAAGGT GCACATCCAT CCTGATGCTG GTCACCGGAG GACGGCTCAG 
CGGTCTGATG CCTGGAGCAC CACTGCAGCC AGAAAGCGAG GGAAGGTGCT GAGCTACTGG 
TGCTTCAGTC CCGGCCACAG CATGCACGAG CTGGTCCGCC AGGGCGTCCG CTCCCTCATC 
CTTACCAGCG GCACGCTGGC CCCGGTGTCC TCCTTTGCTC TGGAGATGCA GATCCCTTTC 
CCAGTCTGCC TGGAGAACCC ACACATCATC GACAAGCACC AGATCTGGGT GGGGGTCGTC 
CCCAGAGGCC CCGATGGAGC CCAGTTGAGC TCCGCGTTTG ACAGACGGTT TTCCGAGGAG 
TGCTTATCCT CCCTGGGGAA GGCTCTGGGC AACATCGCCC GCGTGGTGCC CTATGGGCTC 
CTGATCTTCT TCCCTTCCTA TCCTGTCATG GAGAAGAGCC TGGAGTTCTG GCGGGCCCGC 
GACTTGGCCA GGAAGATGGA GGCGCTGAAG CCGCTGTTTG TGGAGCCCAG GAGCAAAGGC 
AGCTTCTCCG AGACCATCAG TGCTTACTAT GCAAGGGTTG CCGCCCCTGG GTCCACCGGC 
GCCACCTTCC TGGCGGTCTG CCGGGGCAAG GCCAGCGAGG GGCTGGACTT CTCAGACACG 
AATGGCCGTG GTGTGATTGT CACGGGCCTC CCGTACCCCC CACGCATGGA CCCCCGGGTT 
GTCCTCAAGA TGCAGTTCCT GGATGAGATG AAGGGCCAGG GTGGGGCTGG GGGCCAGTTC 
CTCTCTGGGC AGGAGTGGTA CCGGCAGCAG GCGTCCAGGG CTGTGAACCA GGCCATCGGG 
CGAGTGATCC GGCACCGCCA GGACTACGGA GCTGTCTTCC TCTGTGACCA CAGGTTCGCC 
TTTGCCGACG CAAGAGCCCA ACTGCCCTCC TGGGTGCGTC CCCACGTCAG GGTGTATGAC 
AACTTTGGCC ATGTCATCCG AGACGTGGCC CAGTTCTTCC GTGTTGCCGA GCGAACTATG 
CCAGCGCCGG CCCCCCGGGC TACAGCACCC AGTGTGCGTG GAGAAGATGC TGTCAGCGAG 
GCCAAGTCGC CTGGCCCCTT CTTCTCCACC AGGAAAGCTA AGAGTCTGGA CCTGCATGTC 
CCCAGCCTGA AGCAGAGGTC CTCAGGGTCA CCAGCTGCCG GGGACCCCGA GAGTAGCCTG 
TGTGTGGAGT ATGAGCAGGA GCCAGTTCCT GCCCGGCAGA GGCCCAGGGG GCTGCTGGCC 
GCCCTGGAGC ACAGCGAACA GCGGGCGGGG AGCCCTGGCG AGGAGCAGGC CCACAGCTGC 
TCCACCCTGT CCCTCCTGTC TGAGAAGAGG CCGGCAGAAG AACCGCGAGG AGGGAGGAAG 
AAGATCCGGC TGGTCAGCCA CCCGGAGGAG CCCGTGGCTG GTGCACAGAC GGACAGGGCC 
AAGCTCTTCA TGGTGGCCGT GAAGCAGGAG TTGAGCCAAG CCAACTTTGC CACCTTCACC 
CAGGCCCTGC AGGACTACAA GGGTTCCGAT GACTTCGCCG CCCTGGCCGC CTGTCTCGGC 
CCCCTCTTTG CTGAGGACCC CAAGAAGCAC AACCTGCTCC AAGGCTTCTA CCAGTTTGTG 
CGGCCCCACC ATAAGCAGCA GTTTGAGGAG GTCTGTATCC AGCTGACAGG ACGAGGCTGT 
GGCTATCGGC CTGAGCACAG CATTCCCCGA AGGCAGCGGG CACAGCCGGT CCTGGACCCC 
ACTGGAAGAA CGGCGCCGGA TCCCAAGCTG ACCGTGTCCA CGGCTGCAGC CCAGCAGCTG 
GACCCCCAAG AGCACCTGAA CCAGGGCAGG CCCCACCTGT CGCCCAGGCC ACCCCCAACA 
GGAGACCCTG GCAGCCAACC ACAGTGGGGG TCTGGAGTGC CCAGAGCAGG GAAGCAGGGC 
CAGCACGCCG TGAGCGCCTA CCTGGCTGAT GCCCGCAGGG CCCTGGGGTC CGCGGGCTGT 
AGCCAACTCT TGGCAGCGCT GACAGCCTAT AAGCAAGACG ACGACCTCGA CAAGGTGCTG 
GCTGTGTTGG CCGCCCTGAC CACTGCAAAG CCAGAGGACT TCCCCCTGCT GCACAGGTTC 
AGCATGTTTG TGCGTCCACA CCACAAGCAG CGCTTCTCAC AGACGTGCAC AGACCTGACC 
GGCCGGCCCT ACCCGGGCAT GGAGCCACCG GGACCCCAGG AGGAGAGGCT TGCCGTGCCT 
CCTGTGCTTA CCCACAGGGC TCCCCAACCA GGCCCCTCAC GGTCCGAGAA GACCGGGAAG 
ACCCAGAGCA AGATCTCGTC CTTCCTTAGA CAGAGGCCAG CAGGGACTGT GGGGGCGGGC 
GGTGAGGATG CAGGTCCCAG CCAGTCCTCA GGACCTCCCC ACGGGCCTGC AGCATCTGAG 
TGGGGCCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116575.3
CDS	828..4559
Translation	MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRSRCRATLWVLETAPPRPTVLSPTRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGL

Target ORF information:

RefSeq Version	NM_032957.4
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032957.4

ORF Insert Sequence:

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGCTCAC GCTGCAGGGC CACGCTGTGG 
GTGTTGGAGA CAGCTCCTCC TCGACCCACG GTGCTCTCTC CCACCAGGCC TAAGGTGTGT 
GTGCTGGGCT CCCGGGAGCA GCTGTGCATC CATCCTGAGG TGAAGAAACA AGAGAGTAAC 
CATCTACAGA TCCACTTGTG CCGTAAGAAG GTGGCAAGTC GCTCCTGTCA TTTCTACAAC 
AACGTAGAAG AAAAAAGCCT GGAGCAGGAG CTGGCCAGCC CCATCCTGGA CATTGAGGAC 
TTGGTCAAGA GCGGAAGCAA GCACAGGGTG TGCCCTTACT ACCTGTCCCG GAACCTGAAG 
CAGCAAGCCG ACATCATATT CATGCCGTAC AATTACTTGT TGGATGCCAA GAGCCGCAGA 
GCACACAACA TTGACCTGAA GGGGACAGTC GTGATCTTTG ACGAAGCTCA CAACGTGGAG 
AAGATGTGTG AAGAATCGGC ATCCTTTGAC CTGACTCCCC ATGACCTGGC TTCAGGACTG 
GACGTCATAG ACCAGGTGCT GGAGGAGCAG ACCAAGGCAG CGCAGCAGGG TGAGCCCCAC 
CCGGAGTTCA GCGCGGACTC CCCCAGCCCA GGGCTGAACA TGGAGCTGGA AGACATTGCA 
AAGCTGAAGA TGATCCTGCT GCGCCTGGAG GGGGCCATCG ATGCTGTTGA GCTGCCTGGA 
GACGACAGCG GTGTCACCAA GCCAGGGAGC TACATCTTTG AGCTGTTTGC TGAAGCCCAG 
ATCACGTTTC AGACCAAGGG CTGCATCCTG GACTCGCTGG ACCAGATCAT CCAGCACCTG 
GCAGGACGTG CTGGAGTGTT CACCAACACG GCCGGACTGC AGAAGCTGGC GGACATTATC 
CAGATTGTGT TCAGTGTGGA CCCCTCCGAG GGCAGCCCTG GTTCCCCAGC AGGGCTGGGG 
GCCTTACAGT CCTATAAGGT GCACATCCAT CCTGATGCTG GTCACCGGAG GACGGCTCAG 
CGGTCTGATG CCTGGAGCAC CACTGCAGCC AGAAAGCGAG GGAAGGTGCT GAGCTACTGG 
TGCTTCAGTC CCGGCCACAG CATGCACGAG CTGGTCCGCC AGGGCGTCCG CTCCCTCATC 
CTTACCAGCG GCACGCTGGC CCCGGTGTCC TCCTTTGCTC TGGAGATGCA GATCCCTTTC 
CCAGTCTGCC TGGAGAACCC ACACATCATC GACAAGCACC AGATCTGGGT GGGGGTCGTC 
CCCAGAGGCC CCGATGGAGC CCAGTTGAGC TCCGCGTTTG ACAGACGGTT TTCCGAGGAG 
TGCTTATCCT CCCTGGGGAA GGCTCTGGGC AACATCGCCC GCGTGGTGCC CTATGGGCTC 
CTGATCTTCT TCCCTTCCTA TCCTGTCATG GAGAAGAGCC TGGAGTTCTG GCGGGCCCGC 
GACTTGGCCA GGAAGATGGA GGCGCTGAAG CCGCTGTTTG TGGAGCCCAG GAGCAAAGGC 
AGCTTCTCCG AGACCATCAG TGCTTACTAT GCAAGGGTTG CCGCCCCTGG GTCCACCGGC 
GCCACCTTCC TGGCGGTCTG CCGGGGCAAG GCCAGCGAGG GGCTGGACTT CTCAGACACG 
AATGGCCGTG GTGTGATTGT CACGGGCCTC CCGTACCCCC CACGCATGGA CCCCCGGGTT 
GTCCTCAAGA TGCAGTTCCT GGATGAGATG AAGGGCCAGG GTGGGGCTGG GGGCCAGTTC 
CTCTCTGGGC AGGAGTGGTA CCGGCAGCAG GCGTCCAGGG CTGTGAACCA GGCCATCGGG 
CGAGTGATCC GGCACCGCCA GGACTACGGA GCTGTCTTCC TCTGTGACCA CAGGTTCGCC 
TTTGCCGACG CAAGAGCCCA ACTGCCCTCC TGGGTGCGTC CCCACGTCAG GGTGTATGAC 
AACTTTGGCC ATGTCATCCG AGACGTGGCC CAGTTCTTCC GTGTTGCCGA GCGAACTATG 
CCAGCGCCGG CCCCCCGGGC TACAGCACCC AGTGTGCGTG GAGAAGATGC TGTCAGCGAG 
GCCAAGTCGC CTGGCCCCTT CTTCTCCACC AGGAAAGCTA AGAGTCTGGA CCTGCATGTC 
CCCAGCCTGA AGCAGAGGTC CTCAGGGTCA CCAGCTGCCG GGGACCCCGA GAGTAGCCTG 
TGTGTGGAGT ATGAGCAGGA GCCAGTTCCT GCCCGGCAGA GGCCCAGGGG GCTGCTGGCC 
GCCCTGGAGC ACAGCGAACA GCGGGCGGGG AGCCCTGGCG AGGAGCAGGC CCACAGCTGC 
TCCACCCTGT CCCTCCTGTC TGAGAAGAGG CCGGCAGAAG AACCGCGAGG AGGGAGGAAG 
AAGATCCGGC TGGTCAGCCA CCCGGAGGAG CCCGTGGCTG GTGCACAGAC GGACAGGGCC 
AAGCTCTTCA TGGTGGCCGT GAAGCAGGAG TTGAGCCAAG CCAACTTTGC CACCTTCACC 
CAGGCCCTGC AGGACTACAA GGGTTCCGAT GACTTCGCCG CCCTGGCCGC CTGTCTCGGC 
CCCCTCTTTG CTGAGGACCC CAAGAAGCAC AACCTGCTCC AAGGCTTCTA CCAGTTTGTG 
CGGCCCCACC ATAAGCAGCA GTTTGAGGAG GTCTGTATCC AGCTGACAGG ACGAGGCTGT 
GGCTATCGGC CTGAGCACAG CATTCCCCGA AGGCAGCGGG CACAGCCGGT CCTGGACCCC 
ACTGGAAGAA CGGCGCCGGA TCCCAAGCTG ACCGTGTCCA CGGCTGCAGC CCAGCAGCTG 
GACCCCCAAG AGCACCTGAA CCAGGGCAGG CCCCACCTGT CGCCCAGGCC ACCCCCAACA 
GGAGACCCTG GCAGCCAACC ACAGTGGGGG TCTGGAGTGC CCAGAGCAGG GAAGCAGGGC 
CAGCACGCCG TGAGCGCCTA CCTGGCTGAT GCCCGCAGGG CCCTGGGGTC CGCGGGCTGT 
AGCCAACTCT TGGCAGCGCT GACAGCCTAT AAGCAAGACG ACGACCTCGA CAAGGTGCTG 
GCTGTGTTGG CCGCCCTGAC CACTGCAAAG CCAGAGGACT TCCCCCTGCT GCACAGGTTC 
AGCATGTTTG TGCGTCCACA CCACAAGCAG CGCTTCTCAC AGACGTGCAC AGACCTGACC 
GGCCGGCCCT ACCCGGGCAT GGAGCCACCG GGACCCCAGG AGGAGAGGCT TGCCGTGCCT 
CCTGTGCTTA CCCACAGGGC TCCCCAACCA GGCCCCTCAC GGTCCGAGAA GACCGGGAAG 
ACCCAGAGCA AGATCTCGTC CTTCCTTAGA CAGAGGCCAG CAGGGACTGT GGGGGCGGGC 
GGTGAGGATG CAGGTCCCAG CCAGTCCTCA GGACCTCCCC ACGGGCCTGC AGCATCTGAG 
TGGGGCCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RTEL1 ( NM_032957.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_116575.3 Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mRNA.

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CloneID	OHu19254
Clone ID Related Accession (Same CDS sequence)	NM_032957.4 , NM_032957.5
Accession Version	NM_032957.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3732bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	regulator of telomere elongation helicase 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF217795.1, AK302508.1 and AL353715.21. This sequence is a reference standard in the RefSeqGene project. On Sep 3, 2019 this sequence version replaced NM_032957.4. Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 3, one of which results in a translational frameshift. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302508.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGCTCAC GCTGCAGGGC CACGCTGTGG 
GTGTTGGAGA CAGCTCCTCC TCGACCCACG GTGCTCTCTC CCACCAGGCC TAAGGTGTGT 
GTGCTGGGCT CCCGGGAGCA GCTGTGCATC CATCCTGAGG TGAAGAAACA AGAGAGTAAC 
CATCTACAGA TCCACTTGTG CCGTAAGAAG GTGGCAAGTC GCTCCTGTCA TTTCTACAAC 
AACGTAGAAG AAAAAAGCCT GGAGCAGGAG CTGGCCAGCC CCATCCTGGA CATTGAGGAC 
TTGGTCAAGA GCGGAAGCAA GCACAGGGTG TGCCCTTACT ACCTGTCCCG GAACCTGAAG 
CAGCAAGCCG ACATCATATT CATGCCGTAC AATTACTTGT TGGATGCCAA GAGCCGCAGA 
GCACACAACA TTGACCTGAA GGGGACAGTC GTGATCTTTG ACGAAGCTCA CAACGTGGAG 
AAGATGTGTG AAGAATCGGC ATCCTTTGAC CTGACTCCCC ATGACCTGGC TTCAGGACTG 
GACGTCATAG ACCAGGTGCT GGAGGAGCAG ACCAAGGCAG CGCAGCAGGG TGAGCCCCAC 
CCGGAGTTCA GCGCGGACTC CCCCAGCCCA GGGCTGAACA TGGAGCTGGA AGACATTGCA 
AAGCTGAAGA TGATCCTGCT GCGCCTGGAG GGGGCCATCG ATGCTGTTGA GCTGCCTGGA 
GACGACAGCG GTGTCACCAA GCCAGGGAGC TACATCTTTG AGCTGTTTGC TGAAGCCCAG 
ATCACGTTTC AGACCAAGGG CTGCATCCTG GACTCGCTGG ACCAGATCAT CCAGCACCTG 
GCAGGACGTG CTGGAGTGTT CACCAACACG GCCGGACTGC AGAAGCTGGC GGACATTATC 
CAGATTGTGT TCAGTGTGGA CCCCTCCGAG GGCAGCCCTG GTTCCCCAGC AGGGCTGGGG 
GCCTTACAGT CCTATAAGGT GCACATCCAT CCTGATGCTG GTCACCGGAG GACGGCTCAG 
CGGTCTGATG CCTGGAGCAC CACTGCAGCC AGAAAGCGAG GGAAGGTGCT GAGCTACTGG 
TGCTTCAGTC CCGGCCACAG CATGCACGAG CTGGTCCGCC AGGGCGTCCG CTCCCTCATC 
CTTACCAGCG GCACGCTGGC CCCGGTGTCC TCCTTTGCTC TGGAGATGCA GATCCCTTTC 
CCAGTCTGCC TGGAGAACCC ACACATCATC GACAAGCACC AGATCTGGGT GGGGGTCGTC 
CCCAGAGGCC CCGATGGAGC CCAGTTGAGC TCCGCGTTTG ACAGACGGTT TTCCGAGGAG 
TGCTTATCCT CCCTGGGGAA GGCTCTGGGC AACATCGCCC GCGTGGTGCC CTATGGGCTC 
CTGATCTTCT TCCCTTCCTA TCCTGTCATG GAGAAGAGCC TGGAGTTCTG GCGGGCCCGC 
GACTTGGCCA GGAAGATGGA GGCGCTGAAG CCGCTGTTTG TGGAGCCCAG GAGCAAAGGC 
AGCTTCTCCG AGACCATCAG TGCTTACTAT GCAAGGGTTG CCGCCCCTGG GTCCACCGGC 
GCCACCTTCC TGGCGGTCTG CCGGGGCAAG GCCAGCGAGG GGCTGGACTT CTCAGACACG 
AATGGCCGTG GTGTGATTGT CACGGGCCTC CCGTACCCCC CACGCATGGA CCCCCGGGTT 
GTCCTCAAGA TGCAGTTCCT GGATGAGATG AAGGGCCAGG GTGGGGCTGG GGGCCAGTTC 
CTCTCTGGGC AGGAGTGGTA CCGGCAGCAG GCGTCCAGGG CTGTGAACCA GGCCATCGGG 
CGAGTGATCC GGCACCGCCA GGACTACGGA GCTGTCTTCC TCTGTGACCA CAGGTTCGCC 
TTTGCCGACG CAAGAGCCCA ACTGCCCTCC TGGGTGCGTC CCCACGTCAG GGTGTATGAC 
AACTTTGGCC ATGTCATCCG AGACGTGGCC CAGTTCTTCC GTGTTGCCGA GCGAACTATG 
CCAGCGCCGG CCCCCCGGGC TACAGCACCC AGTGTGCGTG GAGAAGATGC TGTCAGCGAG 
GCCAAGTCGC CTGGCCCCTT CTTCTCCACC AGGAAAGCTA AGAGTCTGGA CCTGCATGTC 
CCCAGCCTGA AGCAGAGGTC CTCAGGGTCA CCAGCTGCCG GGGACCCCGA GAGTAGCCTG 
TGTGTGGAGT ATGAGCAGGA GCCAGTTCCT GCCCGGCAGA GGCCCAGGGG GCTGCTGGCC 
GCCCTGGAGC ACAGCGAACA GCGGGCGGGG AGCCCTGGCG AGGAGCAGGC CCACAGCTGC 
TCCACCCTGT CCCTCCTGTC TGAGAAGAGG CCGGCAGAAG AACCGCGAGG AGGGAGGAAG 
AAGATCCGGC TGGTCAGCCA CCCGGAGGAG CCCGTGGCTG GTGCACAGAC GGACAGGGCC 
AAGCTCTTCA TGGTGGCCGT GAAGCAGGAG TTGAGCCAAG CCAACTTTGC CACCTTCACC 
CAGGCCCTGC AGGACTACAA GGGTTCCGAT GACTTCGCCG CCCTGGCCGC CTGTCTCGGC 
CCCCTCTTTG CTGAGGACCC CAAGAAGCAC AACCTGCTCC AAGGCTTCTA CCAGTTTGTG 
CGGCCCCACC ATAAGCAGCA GTTTGAGGAG GTCTGTATCC AGCTGACAGG ACGAGGCTGT 
GGCTATCGGC CTGAGCACAG CATTCCCCGA AGGCAGCGGG CACAGCCGGT CCTGGACCCC 
ACTGGAAGAA CGGCGCCGGA TCCCAAGCTG ACCGTGTCCA CGGCTGCAGC CCAGCAGCTG 
GACCCCCAAG AGCACCTGAA CCAGGGCAGG CCCCACCTGT CGCCCAGGCC ACCCCCAACA 
GGAGACCCTG GCAGCCAACC ACAGTGGGGG TCTGGAGTGC CCAGAGCAGG GAAGCAGGGC 
CAGCACGCCG TGAGCGCCTA CCTGGCTGAT GCCCGCAGGG CCCTGGGGTC CGCGGGCTGT 
AGCCAACTCT TGGCAGCGCT GACAGCCTAT AAGCAAGACG ACGACCTCGA CAAGGTGCTG 
GCTGTGTTGG CCGCCCTGAC CACTGCAAAG CCAGAGGACT TCCCCCTGCT GCACAGGTTC 
AGCATGTTTG TGCGTCCACA CCACAAGCAG CGCTTCTCAC AGACGTGCAC AGACCTGACC 
GGCCGGCCCT ACCCGGGCAT GGAGCCACCG GGACCCCAGG AGGAGAGGCT TGCCGTGCCT 
CCTGTGCTTA CCCACAGGGC TCCCCAACCA GGCCCCTCAC GGTCCGAGAA GACCGGGAAG 
ACCCAGAGCA AGATCTCGTC CTTCCTTAGA CAGAGGCCAG CAGGGACTGT GGGGGCGGGC 
GGTGAGGATG CAGGTCCCAG CCAGTCCTCA GGACCTCCCC ACGGGCCTGC AGCATCTGAG 
TGGGGCCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116575.3
CDS	326..4057
Translation	MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRSRCRATLWVLETAPPRPTVLSPTRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGL

Target ORF information:

RefSeq Version	NM_032957.5
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032957.5

ORF Insert Sequence:

ATGCCCAAGA TAGTCCTGAA TGGTGTGACC GTAGACTTCC CTTTCCAGCC CTACAAATGC 
CAACAGGAGT ACATGACCAA GGTCCTGGAA TGTCTGCAGC AGAAGGTGAA TGGCATCCTG 
GAGAGCCCTA CGGGTACAGG GAAGACGCTG TGCCTGCTGT GCACCACGCT GGCCTGGCGA 
GAACACCTCC GAGACGGCAT CTCTGCCCGC AAGATTGCCG AGAGGGCGCA AGGAGAGCTT 
TTCCCGGATC GGGCCTTGTC ATCCTGGGGC AACGCTGCTG CTGCTGCTGG AGACCCCATA 
GCTTGCTACA CGGACATCCC AAAGATTATT TACGCCTCCA GGACCCACTC GCAACTCACA 
CAGGTCATCA ACGAGCTTCG GAACACCTCC TACCGCTCAC GCTGCAGGGC CACGCTGTGG 
GTGTTGGAGA CAGCTCCTCC TCGACCCACG GTGCTCTCTC CCACCAGGCC TAAGGTGTGT 
GTGCTGGGCT CCCGGGAGCA GCTGTGCATC CATCCTGAGG TGAAGAAACA AGAGAGTAAC 
CATCTACAGA TCCACTTGTG CCGTAAGAAG GTGGCAAGTC GCTCCTGTCA TTTCTACAAC 
AACGTAGAAG AAAAAAGCCT GGAGCAGGAG CTGGCCAGCC CCATCCTGGA CATTGAGGAC 
TTGGTCAAGA GCGGAAGCAA GCACAGGGTG TGCCCTTACT ACCTGTCCCG GAACCTGAAG 
CAGCAAGCCG ACATCATATT CATGCCGTAC AATTACTTGT TGGATGCCAA GAGCCGCAGA 
GCACACAACA TTGACCTGAA GGGGACAGTC GTGATCTTTG ACGAAGCTCA CAACGTGGAG 
AAGATGTGTG AAGAATCGGC ATCCTTTGAC CTGACTCCCC ATGACCTGGC TTCAGGACTG 
GACGTCATAG ACCAGGTGCT GGAGGAGCAG ACCAAGGCAG CGCAGCAGGG TGAGCCCCAC 
CCGGAGTTCA GCGCGGACTC CCCCAGCCCA GGGCTGAACA TGGAGCTGGA AGACATTGCA 
AAGCTGAAGA TGATCCTGCT GCGCCTGGAG GGGGCCATCG ATGCTGTTGA GCTGCCTGGA 
GACGACAGCG GTGTCACCAA GCCAGGGAGC TACATCTTTG AGCTGTTTGC TGAAGCCCAG 
ATCACGTTTC AGACCAAGGG CTGCATCCTG GACTCGCTGG ACCAGATCAT CCAGCACCTG 
GCAGGACGTG CTGGAGTGTT CACCAACACG GCCGGACTGC AGAAGCTGGC GGACATTATC 
CAGATTGTGT TCAGTGTGGA CCCCTCCGAG GGCAGCCCTG GTTCCCCAGC AGGGCTGGGG 
GCCTTACAGT CCTATAAGGT GCACATCCAT CCTGATGCTG GTCACCGGAG GACGGCTCAG 
CGGTCTGATG CCTGGAGCAC CACTGCAGCC AGAAAGCGAG GGAAGGTGCT GAGCTACTGG 
TGCTTCAGTC CCGGCCACAG CATGCACGAG CTGGTCCGCC AGGGCGTCCG CTCCCTCATC 
CTTACCAGCG GCACGCTGGC CCCGGTGTCC TCCTTTGCTC TGGAGATGCA GATCCCTTTC 
CCAGTCTGCC TGGAGAACCC ACACATCATC GACAAGCACC AGATCTGGGT GGGGGTCGTC 
CCCAGAGGCC CCGATGGAGC CCAGTTGAGC TCCGCGTTTG ACAGACGGTT TTCCGAGGAG 
TGCTTATCCT CCCTGGGGAA GGCTCTGGGC AACATCGCCC GCGTGGTGCC CTATGGGCTC 
CTGATCTTCT TCCCTTCCTA TCCTGTCATG GAGAAGAGCC TGGAGTTCTG GCGGGCCCGC 
GACTTGGCCA GGAAGATGGA GGCGCTGAAG CCGCTGTTTG TGGAGCCCAG GAGCAAAGGC 
AGCTTCTCCG AGACCATCAG TGCTTACTAT GCAAGGGTTG CCGCCCCTGG GTCCACCGGC 
GCCACCTTCC TGGCGGTCTG CCGGGGCAAG GCCAGCGAGG GGCTGGACTT CTCAGACACG 
AATGGCCGTG GTGTGATTGT CACGGGCCTC CCGTACCCCC CACGCATGGA CCCCCGGGTT 
GTCCTCAAGA TGCAGTTCCT GGATGAGATG AAGGGCCAGG GTGGGGCTGG GGGCCAGTTC 
CTCTCTGGGC AGGAGTGGTA CCGGCAGCAG GCGTCCAGGG CTGTGAACCA GGCCATCGGG 
CGAGTGATCC GGCACCGCCA GGACTACGGA GCTGTCTTCC TCTGTGACCA CAGGTTCGCC 
TTTGCCGACG CAAGAGCCCA ACTGCCCTCC TGGGTGCGTC CCCACGTCAG GGTGTATGAC 
AACTTTGGCC ATGTCATCCG AGACGTGGCC CAGTTCTTCC GTGTTGCCGA GCGAACTATG 
CCAGCGCCGG CCCCCCGGGC TACAGCACCC AGTGTGCGTG GAGAAGATGC TGTCAGCGAG 
GCCAAGTCGC CTGGCCCCTT CTTCTCCACC AGGAAAGCTA AGAGTCTGGA CCTGCATGTC 
CCCAGCCTGA AGCAGAGGTC CTCAGGGTCA CCAGCTGCCG GGGACCCCGA GAGTAGCCTG 
TGTGTGGAGT ATGAGCAGGA GCCAGTTCCT GCCCGGCAGA GGCCCAGGGG GCTGCTGGCC 
GCCCTGGAGC ACAGCGAACA GCGGGCGGGG AGCCCTGGCG AGGAGCAGGC CCACAGCTGC 
TCCACCCTGT CCCTCCTGTC TGAGAAGAGG CCGGCAGAAG AACCGCGAGG AGGGAGGAAG 
AAGATCCGGC TGGTCAGCCA CCCGGAGGAG CCCGTGGCTG GTGCACAGAC GGACAGGGCC 
AAGCTCTTCA TGGTGGCCGT GAAGCAGGAG TTGAGCCAAG CCAACTTTGC CACCTTCACC 
CAGGCCCTGC AGGACTACAA GGGTTCCGAT GACTTCGCCG CCCTGGCCGC CTGTCTCGGC 
CCCCTCTTTG CTGAGGACCC CAAGAAGCAC AACCTGCTCC AAGGCTTCTA CCAGTTTGTG 
CGGCCCCACC ATAAGCAGCA GTTTGAGGAG GTCTGTATCC AGCTGACAGG ACGAGGCTGT 
GGCTATCGGC CTGAGCACAG CATTCCCCGA AGGCAGCGGG CACAGCCGGT CCTGGACCCC 
ACTGGAAGAA CGGCGCCGGA TCCCAAGCTG ACCGTGTCCA CGGCTGCAGC CCAGCAGCTG 
GACCCCCAAG AGCACCTGAA CCAGGGCAGG CCCCACCTGT CGCCCAGGCC ACCCCCAACA 
GGAGACCCTG GCAGCCAACC ACAGTGGGGG TCTGGAGTGC CCAGAGCAGG GAAGCAGGGC 
CAGCACGCCG TGAGCGCCTA CCTGGCTGAT GCCCGCAGGG CCCTGGGGTC CGCGGGCTGT 
AGCCAACTCT TGGCAGCGCT GACAGCCTAT AAGCAAGACG ACGACCTCGA CAAGGTGCTG 
GCTGTGTTGG CCGCCCTGAC CACTGCAAAG CCAGAGGACT TCCCCCTGCT GCACAGGTTC 
AGCATGTTTG TGCGTCCACA CCACAAGCAG CGCTTCTCAC AGACGTGCAC AGACCTGACC 
GGCCGGCCCT ACCCGGGCAT GGAGCCACCG GGACCCCAGG AGGAGAGGCT TGCCGTGCCT 
CCTGTGCTTA CCCACAGGGC TCCCCAACCA GGCCCCTCAC GGTCCGAGAA GACCGGGAAG 
ACCCAGAGCA AGATCTCGTC CTTCCTTAGA CAGAGGCCAG CAGGGACTGT GGGGGCGGGC 
GGTGAGGATG CAGGTCCCAG CCAGTCCTCA GGACCTCCCC ACGGGCCTGC AGCATCTGAG 
TGGGGCCTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Heterozygous
Blood advances2(1)36-48(2018 Jan)
Marsh JCW,Gutierrez-Rodrigues F,Cooper J,Jiang J,Gandhi S,Kajigaya S,Feng X,Ibanez MDPF,Donaires FS,Lopes da Silva JP,Li Z,Das S,Ibanez M,Smith AE,Lea N,Best S,Ireland R,Kulasekararaj AG,McLornan DP,Pagliuca A,Callebaut I,Young NS,Calado RT,Townsley DM,Mufti GJ

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RTEL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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