FBXO40 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FBXO40
Entrez Gene ID	51725
Full Name	F-box protein 40
Synonyms	FBX40
General protein information	Preferred Names F-box protein 40 Names F-box only protein 40 muscle disease-related protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q13.33
Summary	Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].
Disorder MIM:	609107

mRNA and Protein(s)

mRNA	Protein	Name
NM_016298.3	NP_057382.2	F-box only protein 40
NM_016298.4	NP_057382.2	F-box only protein 40

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	si:dkeyp-69c1.10	XP_005161308.1
Pan troglodytes (chimpanzee)	FBXO40	XP_526281.2
Homo sapiens (human)	FBXO40	NP_057382.2
Bos taurus (cattle)	FBXO40	NP_001193322.1
Mus musculus (house mouse)	Fbxo40	NP_001032398.1
Rattus norvegicus (Norway rat)	Fbxo40	XP_344024.5
Xenopus tropicalis (tropical clawed frog)	fbxo40	XP_004912343.1
	FBXO40	XP_001111331.1
Gallus gallus (chicken)	FBXO40	XP_424000.3
Canis lupus familiaris (dog)	FBXO40	XP_005639605.1

Gene Ontology
Bibliography

Related articles in PubMed

A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.
Le Clerc S, Taing L, Ezzedine K, Latreille J, Delaneau O, Labib T, Coulonges C, Bernard A, Melak S, Carpentier W, Malvy D, Jdid R, Galan P, Hercberg S, Morizot F, Guinot C, Tschachler E, Zagury JF
The Journal of investigative dermatology133(4)929-35(2013 Apr)

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
Need AC, Attix DK, McEvoy JM, Cirulli ET, Linney KL, Hunt P, Ge D, Heinzen EL, Maia JM, Shianna KV, Weale ME, Cherkas LF, Clement G, Spector TD, Gibson G, Goldstein DB
Human molecular genetics18(23)4650-61(2009 Dec)

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
Ebstein F, Lange N, Urban S, Seifert U, Kr?ger E, Kloetzel PM
The international journal of biochemistry & cell biology41(5)1205-15(2009 May)

FBXO40, a gene encoding a novel muscle-specific F-box protein, is upregulated in denervation-related muscle atrophy.
Ye J, Zhang Y, Xu J, Zhang Q, Zhu D
Gene404(1-2)53-60(2007 Dec)

Systematic analysis and nomenclature of mammalian F-box proteins.
Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW
Genes & development18(21)2573-80(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FBXO40 may function as a regulator involved in the postnatal myogenesis.
Title: FBXO40, a gene encoding a novel muscle-specific F-box protein, is upregulated in denervation-related muscle atrophy.

The following FBXO40 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FBXO40 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31546	NM_016298.4 Latest version!	Homo sapiens F-box protein 40 (FBXO40), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu31546	NM_016298.3	Homo sapiens F-box protein 40 (FBXO40), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FBXO40 ( NM_016298.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057382.2 Homo sapiens F-box protein 40 (FBXO40), mRNA.

Price & Availability↑

CloneID	OHu31546
Clone ID Related Accession (Same CDS sequence)	NM_016298.3 , NM_016298.4
Accession Version	NM_016298.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	F-box only protein 40
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB081227.1, BC109275.1, AC063920.19 and AB033021.1. On Aug 28, 2007 this sequence version replaced NM_016298.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB033021.1, SRR1803613.5063.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151741, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAAG CCCGCAGATC CCCGCCAGGG CACCACAGGC ATTGTGAGGG ATGCTTCAAC 
CGCCACTGCC ACATTCCTGT GGAACCCAAC ACCTCCTGCC TGGTAATAAG CTGCCACCTG 
CTCTGTGGTG CCACCTTCCA CATGTGCAAA GAGGCAGAGC ACCAGCTCCT CTGCCCTTTA 
GAGCAGGTTC CGTGCCTCAA CTCCGAATAT GGCTGCCCTC TGTCCATGTC CCGCCACAAA 
CTGGCCAAGC ACCTGCAGGT GTGCCCCGCC AGCGTGGTCT GCTGCTCCAT GGAGTGGAAC 
CGCTGGCCAA ATGTGGACTC TGAAACCACC CTTCATGAAA ACATCATGAA AGAGACCCCC 
AGTGAGGAGT GTTTGGACAC AGCCCTGGCC CTGCAGGATC AGAAGGTCCT CTTCAGATCC 
TTGAAAATGG TGGAACTTTT CCCAGAAACT AGAGAGGCTA CTGAGGAGGA ACCAACTATG 
AATGGTGAAA CCAGTGTGGA GGAAATGGGA GGAGCAGTGG GTGGAGTGGA TATCGGTTTG 
GTACCACATG GTCTGTCAGC AACTAATGGG GAGATGGCAG AGCTAAGTCA AGAAGAACGG 
GAGGTGCTAG CCAAAACCAA AGAAGGGATG GACCTGGTCA AGTTTGGCCA GTGGGAAAAT 
ATTTTCAGCA AAGAGCACGC AGCCTCTGCT TTAACAAATT CATCAGCGAG CTGTGAGAGC 
AAGAACAAGA ATGACTCCGA GAAAGAACAG ATTTCCAGTG GCCATAACAT GGTAGAAGGA 
GAGGGCGCTC CCAAAAAGAA AGAACCACAG GAAAATCAGA AGCAGCAGGA CGTTCGTACA 
GCCATGGAAA CCACAGGGCT TGCCCCTTGG CAGGATGGTG TTCTGGAAAG ACTGAAAACA 
GCTGTGGATG CAAAGGACTA TAACATGTAT CTAGTGCACA ATGGGCGGAT GCTGATACAC 
TTTGGTCAGA TGCCTGCTTG TACACCCAAG GAGAGAGACT TTGTTTATGG CAAGCTGGAG 
GCTCAGGAAG TTAAGACTGT TTACACCTTC AAAGTTCCTG TGAGCTACTG TGGAAAGCGA 
GCTCGACTTG GAGATGCCAT GTTGAGTTGT AAGCCAAGTG AACACAAGGC AGTGGATACT 
TCAGATTTGG GGATCACTGT GGAGGACCTG CCCAAATCAG ATCTCATCAA GACCACCCTC 
CAGTGTGCTT TGGAAAGAGA ACTCAAAGGC CACGTCATCT CTGAATCCAG AAGCATTGAT 
GGACTGTTCA TGGATTTTGC CACACAAACA TACAACTTTG AGCCAGAACA GTTTTCCTCT 
GGGACAGTGC TGGCTGACCT AACCGCTGCC ACCCCAGGGG GACTCCACGT GGAGCTCCAC 
AGCGAGTGTG TGACCAGGAG ACACAACAAA AGCAGCTCTG CCTTCACTTT CACTTGCAAC 
AAATTCTTCA GGAGGGATGA GTTCCCCCTG CACTTCAAGA ATGTCCACAC AGACATTCAG 
TCATGTCTCA ATGGCTGGTT CCAGCATCGA TGCCCCCTCG CCTACTTGGG ATGTACATTT 
GTTCAAAACC ATTTCCGTCC CCCAGGGCAA AAGGCAAAAG TAATCTATAG CCAGGAGCTC 
AAGACCTTTG CCATTAAGCC GGAGGTTGCT CCAGAGCTGA GCGAGGGAAG GAAGAACAAC 
CATCTTTTGG GTCATGGAGG AAAAAGCCAG AATTCTTTAA CCAGCCTGCC CCTGGAGATT 
TTGAAGTACA TTGCTGGGTT CTTGGACAGC GTCAGCCTGG CCCAGCTCTC CCAGGTGTCT 
GTGCTGATGA GGAATATCTG TGCCACTTTG TTACAAGAGA GAGGAATGGT CCTTTTGCAA 
TGGAAGAAAA AGAGGTATTC CCATGGAGGC ACCTCCTGGA GAGTCCACAG AGAGATCTGG 
CAGTTCAGCA GCCTCTTCTC CAAAATCAAG AGCTGGGAGT TTAATGAAGT CACCTCCATG 
TCTGAGCACC TGAAGTCCTG TCCTTTCAAC ATTGTAGAGC ACAAAACTGA CCCGATTCTT 
TTGACTAGCA TGTGTCAGCC CCGTGAGCAG GCCCGAGAGA GCTTAGTCTC CACCTTTAGA 
ATCAGACCAC GAGGAAGATA CGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057382.2
CDS	211..2340
Translation	MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPLEQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETPSEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGGAVGGVDIGLVPHGLSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCESKNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKRARLGDAMLSCKPSEHKAVDTSDLGITVEDLPKSDLIKTTLQCALERELKGHVISESRSIDGLFMDFATQTYNFEPEQFSSGTVLADLTAATPGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVSVLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSMSEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS

Target ORF information:

RefSeq Version	NM_016298.3
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 40 (FBXO40), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016298.3

ORF Insert Sequence:

ATGGGGAAAG CCCGCAGATC CCCGCCAGGG CACCACAGGC ATTGTGAGGG ATGCTTCAAC 
CGCCACTGCC ACATTCCTGT GGAACCCAAC ACCTCCTGCC TGGTAATAAG CTGCCACCTG 
CTCTGTGGTG CCACCTTCCA CATGTGCAAA GAGGCAGAGC ACCAGCTCCT CTGCCCTTTA 
GAGCAGGTTC CGTGCCTCAA CTCCGAATAT GGCTGCCCTC TGTCCATGTC CCGCCACAAA 
CTGGCCAAGC ACCTGCAGGT GTGCCCCGCC AGCGTGGTCT GCTGCTCCAT GGAGTGGAAC 
CGCTGGCCAA ATGTGGACTC TGAAACCACC CTTCATGAAA ACATCATGAA AGAGACCCCC 
AGTGAGGAGT GTTTGGACAC AGCCCTGGCC CTGCAGGATC AGAAGGTCCT CTTCAGATCC 
TTGAAAATGG TGGAACTTTT CCCAGAAACT AGAGAGGCTA CTGAGGAGGA ACCAACTATG 
AATGGTGAAA CCAGTGTGGA GGAAATGGGA GGAGCAGTGG GTGGAGTGGA TATCGGTTTG 
GTACCACATG GTCTGTCAGC AACTAATGGG GAGATGGCAG AGCTAAGTCA AGAAGAACGG 
GAGGTGCTAG CCAAAACCAA AGAAGGGATG GACCTGGTCA AGTTTGGCCA GTGGGAAAAT 
ATTTTCAGCA AAGAGCACGC AGCCTCTGCT TTAACAAATT CATCAGCGAG CTGTGAGAGC 
AAGAACAAGA ATGACTCCGA GAAAGAACAG ATTTCCAGTG GCCATAACAT GGTAGAAGGA 
GAGGGCGCTC CCAAAAAGAA AGAACCACAG GAAAATCAGA AGCAGCAGGA CGTTCGTACA 
GCCATGGAAA CCACAGGGCT TGCCCCTTGG CAGGATGGTG TTCTGGAAAG ACTGAAAACA 
GCTGTGGATG CAAAGGACTA TAACATGTAT CTAGTGCACA ATGGGCGGAT GCTGATACAC 
TTTGGTCAGA TGCCTGCTTG TACACCCAAG GAGAGAGACT TTGTTTATGG CAAGCTGGAG 
GCTCAGGAAG TTAAGACTGT TTACACCTTC AAAGTTCCTG TGAGCTACTG TGGAAAGCGA 
GCTCGACTTG GAGATGCCAT GTTGAGTTGT AAGCCAAGTG AACACAAGGC AGTGGATACT 
TCAGATTTGG GGATCACTGT GGAGGACCTG CCCAAATCAG ATCTCATCAA GACCACCCTC 
CAGTGTGCTT TGGAAAGAGA ACTCAAAGGC CACGTCATCT CTGAATCCAG AAGCATTGAT 
GGACTGTTCA TGGATTTTGC CACACAAACA TACAACTTTG AGCCAGAACA GTTTTCCTCT 
GGGACAGTGC TGGCTGACCT AACCGCTGCC ACCCCAGGGG GACTCCACGT GGAGCTCCAC 
AGCGAGTGTG TGACCAGGAG ACACAACAAA AGCAGCTCTG CCTTCACTTT CACTTGCAAC 
AAATTCTTCA GGAGGGATGA GTTCCCCCTG CACTTCAAGA ATGTCCACAC AGACATTCAG 
TCATGTCTCA ATGGCTGGTT CCAGCATCGA TGCCCCCTCG CCTACTTGGG ATGTACATTT 
GTTCAAAACC ATTTCCGTCC CCCAGGGCAA AAGGCAAAAG TAATCTATAG CCAGGAGCTC 
AAGACCTTTG CCATTAAGCC GGAGGTTGCT CCAGAGCTGA GCGAGGGAAG GAAGAACAAC 
CATCTTTTGG GTCATGGAGG AAAAAGCCAG AATTCTTTAA CCAGCCTGCC CCTGGAGATT 
TTGAAGTACA TTGCTGGGTT CTTGGACAGC GTCAGCCTGG CCCAGCTCTC CCAGGTGTCT 
GTGCTGATGA GGAATATCTG TGCCACTTTG TTACAAGAGA GAGGAATGGT CCTTTTGCAA 
TGGAAGAAAA AGAGGTATTC CCATGGAGGC ACCTCCTGGA GAGTCCACAG AGAGATCTGG 
CAGTTCAGCA GCCTCTTCTC CAAAATCAAG AGCTGGGAGT TTAATGAAGT CACCTCCATG 
TCTGAGCACC TGAAGTCCTG TCCTTTCAAC ATTGTAGAGC ACAAAACTGA CCCGATTCTT 
TTGACTAGCA TGTGTCAGCC CCGTGAGCAG GCCCGAGAGA GCTTAGTCTC CACCTTTAGA 
ATCAGACCAC GAGGAAGATA CGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO40 ( NM_016298.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057382.2 Homo sapiens F-box protein 40 (FBXO40), mRNA.

Price & Availability↑

CloneID	OHu31546
Clone ID Related Accession (Same CDS sequence)	NM_016298.3 , NM_016298.4
Accession Version	NM_016298.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	F-box only protein 40
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB081227.1, BC109275.1, AC063920.19 and AB033021.1. On Nov 23, 2018 this sequence version replaced NM_016298.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB033021.1, SRR1803613.5063.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151741, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000338040.6/ ENSP00000337510.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGAAAG CCCGCAGATC CCCGCCAGGG CACCACAGGC ATTGTGAGGG ATGCTTCAAC 
CGCCACTGCC ACATTCCTGT GGAACCCAAC ACCTCCTGCC TGGTAATAAG CTGCCACCTG 
CTCTGTGGTG CCACCTTCCA CATGTGCAAA GAGGCAGAGC ACCAGCTCCT CTGCCCTTTA 
GAGCAGGTTC CGTGCCTCAA CTCCGAATAT GGCTGCCCTC TGTCCATGTC CCGCCACAAA 
CTGGCCAAGC ACCTGCAGGT GTGCCCCGCC AGCGTGGTCT GCTGCTCCAT GGAGTGGAAC 
CGCTGGCCAA ATGTGGACTC TGAAACCACC CTTCATGAAA ACATCATGAA AGAGACCCCC 
AGTGAGGAGT GTTTGGACAC AGCCCTGGCC CTGCAGGATC AGAAGGTCCT CTTCAGATCC 
TTGAAAATGG TGGAACTTTT CCCAGAAACT AGAGAGGCTA CTGAGGAGGA ACCAACTATG 
AATGGTGAAA CCAGTGTGGA GGAAATGGGA GGAGCAGTGG GTGGAGTGGA TATCGGTTTG 
GTACCACATG GTCTGTCAGC AACTAATGGG GAGATGGCAG AGCTAAGTCA AGAAGAACGG 
GAGGTGCTAG CCAAAACCAA AGAAGGGATG GACCTGGTCA AGTTTGGCCA GTGGGAAAAT 
ATTTTCAGCA AAGAGCACGC AGCCTCTGCT TTAACAAATT CATCAGCGAG CTGTGAGAGC 
AAGAACAAGA ATGACTCCGA GAAAGAACAG ATTTCCAGTG GCCATAACAT GGTAGAAGGA 
GAGGGCGCTC CCAAAAAGAA AGAACCACAG GAAAATCAGA AGCAGCAGGA CGTTCGTACA 
GCCATGGAAA CCACAGGGCT TGCCCCTTGG CAGGATGGTG TTCTGGAAAG ACTGAAAACA 
GCTGTGGATG CAAAGGACTA TAACATGTAT CTAGTGCACA ATGGGCGGAT GCTGATACAC 
TTTGGTCAGA TGCCTGCTTG TACACCCAAG GAGAGAGACT TTGTTTATGG CAAGCTGGAG 
GCTCAGGAAG TTAAGACTGT TTACACCTTC AAAGTTCCTG TGAGCTACTG TGGAAAGCGA 
GCTCGACTTG GAGATGCCAT GTTGAGTTGT AAGCCAAGTG AACACAAGGC AGTGGATACT 
TCAGATTTGG GGATCACTGT GGAGGACCTG CCCAAATCAG ATCTCATCAA GACCACCCTC 
CAGTGTGCTT TGGAAAGAGA ACTCAAAGGC CACGTCATCT CTGAATCCAG AAGCATTGAT 
GGACTGTTCA TGGATTTTGC CACACAAACA TACAACTTTG AGCCAGAACA GTTTTCCTCT 
GGGACAGTGC TGGCTGACCT AACCGCTGCC ACCCCAGGGG GACTCCACGT GGAGCTCCAC 
AGCGAGTGTG TGACCAGGAG ACACAACAAA AGCAGCTCTG CCTTCACTTT CACTTGCAAC 
AAATTCTTCA GGAGGGATGA GTTCCCCCTG CACTTCAAGA ATGTCCACAC AGACATTCAG 
TCATGTCTCA ATGGCTGGTT CCAGCATCGA TGCCCCCTCG CCTACTTGGG ATGTACATTT 
GTTCAAAACC ATTTCCGTCC CCCAGGGCAA AAGGCAAAAG TAATCTATAG CCAGGAGCTC 
AAGACCTTTG CCATTAAGCC GGAGGTTGCT CCAGAGCTGA GCGAGGGAAG GAAGAACAAC 
CATCTTTTGG GTCATGGAGG AAAAAGCCAG AATTCTTTAA CCAGCCTGCC CCTGGAGATT 
TTGAAGTACA TTGCTGGGTT CTTGGACAGC GTCAGCCTGG CCCAGCTCTC CCAGGTGTCT 
GTGCTGATGA GGAATATCTG TGCCACTTTG TTACAAGAGA GAGGAATGGT CCTTTTGCAA 
TGGAAGAAAA AGAGGTATTC CCATGGAGGC ACCTCCTGGA GAGTCCACAG AGAGATCTGG 
CAGTTCAGCA GCCTCTTCTC CAAAATCAAG AGCTGGGAGT TTAATGAAGT CACCTCCATG 
TCTGAGCACC TGAAGTCCTG TCCTTTCAAC ATTGTAGAGC ACAAAACTGA CCCGATTCTT 
TTGACTAGCA TGTGTCAGCC CCGTGAGCAG GCCCGAGAGA GCTTAGTCTC CACCTTTAGA 
ATCAGACCAC GAGGAAGATA CGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057382.2
CDS	155..2284
Translation	MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPLEQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETPSEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGGAVGGVDIGLVPHGLSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCESKNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKRARLGDAMLSCKPSEHKAVDTSDLGITVEDLPKSDLIKTTLQCALERELKGHVISESRSIDGLFMDFATQTYNFEPEQFSSGTVLADLTAATPGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVSVLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSMSEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS

Target ORF information:

RefSeq Version	NM_016298.4
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 40 (FBXO40), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016298.4

ORF Insert Sequence:

ATGGGGAAAG CCCGCAGATC CCCGCCAGGG CACCACAGGC ATTGTGAGGG ATGCTTCAAC 
CGCCACTGCC ACATTCCTGT GGAACCCAAC ACCTCCTGCC TGGTAATAAG CTGCCACCTG 
CTCTGTGGTG CCACCTTCCA CATGTGCAAA GAGGCAGAGC ACCAGCTCCT CTGCCCTTTA 
GAGCAGGTTC CGTGCCTCAA CTCCGAATAT GGCTGCCCTC TGTCCATGTC CCGCCACAAA 
CTGGCCAAGC ACCTGCAGGT GTGCCCCGCC AGCGTGGTCT GCTGCTCCAT GGAGTGGAAC 
CGCTGGCCAA ATGTGGACTC TGAAACCACC CTTCATGAAA ACATCATGAA AGAGACCCCC 
AGTGAGGAGT GTTTGGACAC AGCCCTGGCC CTGCAGGATC AGAAGGTCCT CTTCAGATCC 
TTGAAAATGG TGGAACTTTT CCCAGAAACT AGAGAGGCTA CTGAGGAGGA ACCAACTATG 
AATGGTGAAA CCAGTGTGGA GGAAATGGGA GGAGCAGTGG GTGGAGTGGA TATCGGTTTG 
GTACCACATG GTCTGTCAGC AACTAATGGG GAGATGGCAG AGCTAAGTCA AGAAGAACGG 
GAGGTGCTAG CCAAAACCAA AGAAGGGATG GACCTGGTCA AGTTTGGCCA GTGGGAAAAT 
ATTTTCAGCA AAGAGCACGC AGCCTCTGCT TTAACAAATT CATCAGCGAG CTGTGAGAGC 
AAGAACAAGA ATGACTCCGA GAAAGAACAG ATTTCCAGTG GCCATAACAT GGTAGAAGGA 
GAGGGCGCTC CCAAAAAGAA AGAACCACAG GAAAATCAGA AGCAGCAGGA CGTTCGTACA 
GCCATGGAAA CCACAGGGCT TGCCCCTTGG CAGGATGGTG TTCTGGAAAG ACTGAAAACA 
GCTGTGGATG CAAAGGACTA TAACATGTAT CTAGTGCACA ATGGGCGGAT GCTGATACAC 
TTTGGTCAGA TGCCTGCTTG TACACCCAAG GAGAGAGACT TTGTTTATGG CAAGCTGGAG 
GCTCAGGAAG TTAAGACTGT TTACACCTTC AAAGTTCCTG TGAGCTACTG TGGAAAGCGA 
GCTCGACTTG GAGATGCCAT GTTGAGTTGT AAGCCAAGTG AACACAAGGC AGTGGATACT 
TCAGATTTGG GGATCACTGT GGAGGACCTG CCCAAATCAG ATCTCATCAA GACCACCCTC 
CAGTGTGCTT TGGAAAGAGA ACTCAAAGGC CACGTCATCT CTGAATCCAG AAGCATTGAT 
GGACTGTTCA TGGATTTTGC CACACAAACA TACAACTTTG AGCCAGAACA GTTTTCCTCT 
GGGACAGTGC TGGCTGACCT AACCGCTGCC ACCCCAGGGG GACTCCACGT GGAGCTCCAC 
AGCGAGTGTG TGACCAGGAG ACACAACAAA AGCAGCTCTG CCTTCACTTT CACTTGCAAC 
AAATTCTTCA GGAGGGATGA GTTCCCCCTG CACTTCAAGA ATGTCCACAC AGACATTCAG 
TCATGTCTCA ATGGCTGGTT CCAGCATCGA TGCCCCCTCG CCTACTTGGG ATGTACATTT 
GTTCAAAACC ATTTCCGTCC CCCAGGGCAA AAGGCAAAAG TAATCTATAG CCAGGAGCTC 
AAGACCTTTG CCATTAAGCC GGAGGTTGCT CCAGAGCTGA GCGAGGGAAG GAAGAACAAC 
CATCTTTTGG GTCATGGAGG AAAAAGCCAG AATTCTTTAA CCAGCCTGCC CCTGGAGATT 
TTGAAGTACA TTGCTGGGTT CTTGGACAGC GTCAGCCTGG CCCAGCTCTC CCAGGTGTCT 
GTGCTGATGA GGAATATCTG TGCCACTTTG TTACAAGAGA GAGGAATGGT CCTTTTGCAA 
TGGAAGAAAA AGAGGTATTC CCATGGAGGC ACCTCCTGGA GAGTCCACAG AGAGATCTGG 
CAGTTCAGCA GCCTCTTCTC CAAAATCAAG AGCTGGGAGT TTAATGAAGT CACCTCCATG 
TCTGAGCACC TGAAGTCCTG TCCTTTCAAC ATTGTAGAGC ACAAAACTGA CCCGATTCTT 
TTGACTAGCA TGTGTCAGCC CCGTGAGCAG GCCCGAGAGA GCTTAGTCTC CACCTTTAGA 
ATCAGACCAC GAGGAAGATA CGTCTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.
The Journal of investigative dermatology133(4)929-35(2013 Apr)
Le Clerc S,Taing L,Ezzedine K,Latreille J,Delaneau O,Labib T,Coulonges C,Bernard A,Melak S,Carpentier W,Malvy D,Jdid R,Galan P,Hercberg S,Morizot F,Guinot C,Tschachler E,Zagury JF

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
Human molecular genetics18(23)4650-61(2009 Dec)
Need AC,Attix DK,McEvoy JM,Cirulli ET,Linney KL,Hunt P,Ge D,Heinzen EL,Maia JM,Shianna KV,Weale ME,Cherkas LF,Clement G,Spector TD,Gibson G,Goldstein DB

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
The international journal of biochemistry & cell biology41(5)1205-15(2009 May)
Ebstein F,Lange N,Urban S,Seifert U,Kr?ger E,Kloetzel PM

FBXO40, a gene encoding a novel muscle-specific F-box protein, is upregulated in denervation-related muscle atrophy.
Gene404(1-2)53-60(2007 Dec)
Ye J,Zhang Y,Xu J,Zhang Q,Zhu D

Systematic analysis and nomenclature of mammalian F-box proteins.
Genes & development18(21)2573-80(2004 Nov)
Jin J,Cardozo T,Lovering RC,Elledge SJ,Pagano M,Harper JW

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FBXO40 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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