CAB39 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CAB39
Entrez Gene ID	51719
Full Name	calcium binding protein 39
Synonyms	CGI-66,MO25
General protein information	Preferred Names calcium binding protein 39 Names calcium-binding protein 39 MO25alpha
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q37.1
Disorder MIM:	612174

mRNA and Protein(s)

mRNA	Protein	Name
XM_011511350.2	XP_011509652.1	calcium-binding protein 39 isoform X1
NM_001130849.1	NP_001124321.1	calcium-binding protein 39
NM_016289.3	NP_057373.1	calcium-binding protein 39
NM_001130850.1	NP_001124322.1	calcium-binding protein 39
NM_016289.4	NP_057373.1	calcium-binding protein 39

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CAB39	XP_526055.2
Danio rerio (zebrafish)	cab39	NP_001002145.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011060	XP_308076.3
Oryza sativa (rice)	Os07g0585100	NP_001060123.1
Canis lupus familiaris (dog)	CAB39	XP_534599.2
	CAB39	XP_001112762.1
Mus musculus (house mouse)	Cab39	NP_598542.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000812	XP_311350.2
Arabidopsis thaliana (thale cress)	AT5G47540	NP_199565.4
Arabidopsis thaliana (thale cress)	AT4G17270	NP_193460.1
Xenopus tropicalis (tropical clawed frog)	LOC100486569	XP_002933394.1
Homo sapiens (human)	CAB39	NP_057373.1
Bos taurus (cattle)	CAB39	NP_001039552.1
Drosophila melanogaster (fruit fly)	Mo25	NP_524117.1
Caenorhabditis elegans (roundworm)	mop-25.1	NP_001024819.1
Gallus gallus (chicken)	CAB39	XP_003641786.1
Caenorhabditis elegans (roundworm)	mop-25.2	NP_496092.1

Gene Ontology
Bibliography

Related articles in PubMed

Calcium-binding protein 39 promotes hepatocellular carcinoma growth and metastasis by activating extracellular signal-regulated kinase signaling pathway.
Jiang L, Yan Q, Fang S, Liu M, Li Y, Yuan YF, Li Y, Zhu Y, Qi J, Yang X, Kwong DLW, Guan XY
Hepatology (Baltimore, Md.)66(5)1529-1545(2017 11)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

MiR-451 Promotes Cell Proliferation and Metastasis in Pancreatic Cancer through Targeting CAB39.
Guo R, Gu J, Zhang Z, Wang Y, Gu C
BioMed research international20172381482(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

plays very important oncogenic roles in hepatocellular carcinoma pathogenesis and progression by activating the ERK signaling pathway
Title: Calcium-binding protein 39 promotes hepatocellular carcinoma growth and metastasis by activating extracellular signal-regulated kinase signaling pathway.

miR-451 directly targets CAB39 and negatively regulates its expression and inhibition of CAB39 contributes to the promoted cell viability and invasion
Title: MiR-451 Promotes Cell Proliferation and Metastasis in Pancreatic Cancer through Targeting CAB39.

These data provide molecular understanding of the mechanism by which MO25 isoforms regulates the activity of STE20 family protein kinases.
Title: Structural insights into the activation of MST3 by MO25.

Authors conclude that miR-451 represses glioma in vitro and in vivo, likely through targeting CAB39 directly and inhibiting the PI3K/AKT pathway indirectly.
Title: MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma.

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases.
Title: MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases.

The following CAB39 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CAB39 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24389	NM_016289.4 Latest version!	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24389	NM_001130850.1 Latest version!	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24389	NM_001130849.1 Latest version!	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu68112	XM_011511350.2 Latest version!	Homo sapiens calcium binding protein 39 (CAB39), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu24389	NM_016289.3	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CAB39 ( NM_001130849.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124321.1 Homo sapiens calcium binding protein 39 (CAB39), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24389
Clone ID Related Accession (Same CDS sequence)	NM_001130849.1 , NM_016289.3 , NM_001130850.1 , NM_016289.4
Accession Version	NM_001130849.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	calcium-binding protein 39
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK292382.1, AK000804.1 and AF113536.1. Transcript Variant: This variant (2) represents an alternate non-coding exon in the 5'UTR compared to variant 1. The same protein is encoded by variants 1, 2, and 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK292382.1, SRR1803615.217591.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124321.1
CDS	555..1580
Translation	MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA

Target ORF information:

RefSeq Version	NM_001130849.1
Organism	Homo sapiens(human)
Definition	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130849.1

ORF Insert Sequence:

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAB39 ( NM_016289.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057373.1 Homo sapiens calcium binding protein 39 (CAB39), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24389
Clone ID Related Accession (Same CDS sequence)	NM_001130849.1 , NM_016289.3 , NM_001130850.1 , NM_016289.4
Accession Version	NM_016289.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-11
Organism	Homo sapiens(human)
Product	calcium-binding protein 39
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA886579.1, BC020570.1, BG773506.1, AK000804.1 and AF113536.1. On Aug 6, 2008 this sequence version replaced NM_016289.2. Transcript Variant: This variant (1) represents an alternate non-coding exon in the 5'UTR. The same protein is encoded by variants 1, 2, and 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC020570.1, SRR1660803.138490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057373.1
CDS	433..1458
Translation	MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA

Target ORF information:

RefSeq Version	NM_016289.3
Organism	Homo sapiens(human)
Definition	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016289.3

ORF Insert Sequence:

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAB39 ( NM_001130850.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001124322.1 Homo sapiens calcium binding protein 39 (CAB39), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu24389
Clone ID Related Accession (Same CDS sequence)	NM_001130849.1 , NM_016289.3 , NM_001130850.1 , NM_016289.4
Accession Version	NM_001130850.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	calcium-binding protein 39
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB455871.1, AC084031.5, AK315692.1, AK000804.1 and AF113536.1. Transcript Variant: This variant (3) represents an alternate non-coding exon in the 5'UTR compared to variant 1. The same protein is encoded by variants 1, 2, and 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.98364.1, AK315692.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2146982 [ECO:0000348] ##Evidence-Data-END##

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124322.1
CDS	299..1324
Translation	MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA

Target ORF information:

RefSeq Version	NM_001130850.1
Organism	Homo sapiens(human)
Definition	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130850.1

ORF Insert Sequence:

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAB39 ( NM_016289.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057373.1 Homo sapiens calcium binding protein 39 (CAB39), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24389
Clone ID Related Accession (Same CDS sequence)	NM_001130849.1 , NM_016289.3 , NM_001130850.1 , NM_016289.4
Accession Version	NM_016289.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	calcium-binding protein 39
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA886579.1, BC020570.1, BG773506.1, AK000804.1 and AF113536.1. On Nov 22, 2018 this sequence version replaced NM_016289.3. Transcript Variant: This variant (1) represents an alternate non-coding exon in the 5'UTR. The same protein is encoded by variants 1, 2, and 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC020570.1, SRR1660803.138490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000258418.10/ ENSP00000258418.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057373.1
CDS	433..1458
Translation	MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRFFSEYEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENLKLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTQPILDILLKNQAKLIEFLSKFQNDRTEDEQFNDEKTYLVKQIRDLKRPAQQEA

Target ORF information:

RefSeq Version	NM_016289.4
Organism	Homo sapiens(human)
Definition	Homo sapiens calcium binding protein 39 (CAB39), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016289.4

ORF Insert Sequence:

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTT TTCAGTGAAT ATGAGAAGTT ACTTCATTCA 
GAAAATTATG TGACAAAAAG ACAGTCACTG AAGCTTCTCG GTGAACTACT ACTAGATAGA 
CACAACTTCA CAATTATGAC AAAATACATC AGTAAACCTG AGAACCTCAA ATTAATGATG 
AACCTGCTGC GAGACAAAAG TCGCAACATC CAGTTTGAGG CCTTTCACGT TTTTAAGGTG 
TTTGTAGCCA ATCCTAACAA GACGCAGCCC ATCCTAGACA TCCTCCTCAA GAACCAGGCC 
AAACTCATAG AGTTCCTCAG CAAGTTTCAG AACGACAGGA CGGAGGATGA GCAGTTTAAC 
GACGAGAAGA CCTATTTAGT TAAACAGATC AGGGATTTGA AGAGACCAGC TCAGCAAGAA 
GCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAB39 ( XM_011511350.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011509652.1 Homo sapiens calcium binding protein 39 (CAB39), transcript variant X1, mRNA.

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CloneID	OHu68112
Clone ID Related Accession (Same CDS sequence)	XM_011511350.2
Accession Version	XM_011511350.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	calcium-binding protein 39 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011511350.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTG CCCCACATTT CTGCTGCATA CAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011509652.1
CDS	433..1089
Translation	MPFPFGKSHKSPADIVKNLKESMAVLEKQDISDKKAEKATEEVSKNLVAMKEILYGTNEKEPQTEAVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNNILRRQIGTRTPTVEYICTQQNILFMLLKGYESPEIALNCGIMLRECIRHEPLAKIILWSEQFYDFFRYVEMSTFDIASDAFATFKDLLTRHKLLSAEFLEQHYDRLPHISAAYK

Target ORF information:

RefSeq Version	XM_011511350.2
Organism	Homo sapiens(human)
Definition	Homo sapiens calcium binding protein 39 (CAB39), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011511350.2

ORF Insert Sequence:

ATGCCGTTCC CGTTTGGGAA GTCTCACAAA TCTCCAGCAG ACATTGTGAA GAATCTGAAG 
GAGAGCATGG CTGTTCTGGA AAAGCAAGAC ATTTCTGATA AAAAAGCAGA AAAGGCTACA 
GAAGAAGTTT CCAAAAATCT GGTTGCCATG AAAGAAATTC TGTATGGCAC AAATGAAAAA 
GAGCCTCAGA CAGAAGCAGT AGCTCAACTT GCTCAAGAAC TCTATAATAG TGGGCTCCTT 
AGCACCCTGG TAGCTGATTT ACAGCTCATT GACTTTGAGG GCAAAAAAGA CGTGGCTCAA 
ATTTTCAACA ATATTCTCAG AAGACAAATT GGTACGAGAA CTCCTACTGT TGAATACATC 
TGCACCCAAC AGAATATTTT GTTCATGTTA TTGAAAGGGT ATGAATCTCC AGAAATAGCT 
CTAAATTGTG GAATAATGTT AAGAGAATGC ATCAGACATG AACCACTTGC AAAAATCATT 
TTGTGGTCGG AACAGTTTTA TGATTTCTTC AGATATGTCG AAATGTCAAC ATTTGACATA 
GCTTCAGATG CATTTGCCAC ATTCAAGGAT TTACTTACAA GACATAAATT GCTCAGTGCA 
GAATTTTTGG AACAGCATTA TGATAGATTG CCCCACATTT CTGCTGCATA CAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Calcium-binding protein 39 promotes hepatocellular carcinoma growth and metastasis by activating extracellular signal-regulated kinase signaling pathway.
Hepatology (Baltimore, Md.)66(5)1529-1545(2017 11)
Jiang L,Yan Q,Fang S,Liu M,Li Y,Yuan YF,Li Y,Zhu Y,Qi J,Yang X,Kwong DLW,Guan XY

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

MiR-451 Promotes Cell Proliferation and Metastasis in Pancreatic Cancer through Targeting CAB39.
BioMed research international20172381482(2017)
Guo R,Gu J,Zhang Z,Wang Y,Gu C

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CAB39 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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