CHMP5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CHMP5
Entrez Gene ID	51510
Full Name	charged multivesicular body protein 5
Synonyms	C9orf83,CGI-34,HSPC177,PNAS-2,SNF7DC2,Vps60
General protein information	Preferred Names charged multivesicular body protein 5 Names charged multivesicular body protein 5 SNF7 domain containing 2 SNF7 domain-containing protein 2 apoptosis-related protein PNAS-2 chromatin-modifying protein 5 hVps60 vacuolar protein sorting-associated protein 60
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p13.3
Summary	CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610900

mRNA and Protein(s)

mRNA	Protein	Name
NM_016410.5	NP_057494.3	charged multivesicular body protein 5 isoform 1
NM_016410.6	NP_057494.3	charged multivesicular body protein 5 isoform 1
NM_001195536.1	NP_001182465.1	charged multivesicular body protein 5 isoform 2

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	F41E6.9	NP_505219.1
Kluyveromyces lactis	KLLA0C03608g	XP_452357.1
Pan troglodytes (chimpanzee)	CHMP5	XP_001154646.2
Rattus norvegicus (Norway rat)	Chmp5	NP_001020581.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005100	XP_313976.2
Saccharomyces cerevisiae (baker's yeast)	VPS60	NP_010774.4
Schizosaccharomyces pombe (fission yeast)	SPCC162.06c	NP_588238.1
Arabidopsis thaliana (thale cress)	VPS60.2	NP_568143.1
Oryza sativa (rice)	Os01g0102950	NP_001172117.1
Canis lupus familiaris (dog)	CHMP5	XP_531972.3
Mus musculus (house mouse)	Chmp5	NP_084090.1
Danio rerio (zebrafish)	chmp5b	NP_956674.1
Eremothecium gossypii	AGOS_ADR116C	NP_984212.1
Xenopus tropicalis (tropical clawed frog)	chmp5	NP_001016748.1
Homo sapiens (human)	CHMP5	NP_057494.3
Gallus gallus (chicken)	CHMP5	NP_001264328.1
Drosophila melanogaster (fruit fly)	CG6259	NP_648997.1
Neurospora crassa	NCU04541	XP_955981.1
Oryza sativa (rice)	Os05g0102900	NP_001054389.1
	CHMP5	XP_001100473.1
Bos taurus (cattle)	CHMP5	NP_001029854.1
Magnaporthe oryzae (rice blast fungus)	MGG_09695	XP_003717660.1
Arabidopsis thaliana (thale cress)	VPS60.1	NP_187675.2

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Charged MVB protein 5 is involved in T-cell receptor signaling.
Wi SM, Min Y, Lee KY
Experimental & molecular medicine48e206(2016 Jan)

Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.
Thi?baut R, Esmiol S, Lecine P, Mahfouz B, Hermant A, Nicoletti C, Parnis S, Perroy J, Borg JP, Pascoe L, Hugot JP, Ollendorff V
PloS one11(11)e0165420(2016)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CHMP5 might be involved in the homeostatic regulation of TCR on the cell surface, presumably through TCR recycling or degradation. Thus CHMP5 is implicated in TCR-mediated signaling.
Title: Charged MVB protein 5 is involved in T-cell receptor signaling.

ESCRT-III protein CHMP5 inhibits LIP5-mediated VPS4 activation by inducing a moderate conformational change within LIP5.
Title: A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5.

after CHMP5 inhibition, both Granzyme B/Perforin apoptotic pathway and apoptosis-inducing factor-mediated necrotic pathway were activated, while autophagic pathway was not activated
Title: The role of charged multivesicular body protein 5 in programmed cell death in leukemic cells.

pnas-2 is specifically up-regulated in acute leukemia patients.
Title: [Expression spectra of apoptosis-related gene pnas-2].

PNAS-2 was shown to be anti-apoptotic and may participate in leukemogenesis
Title: PNAS-2: a novel gene probably participating in leukemogenesis.

The following CHMP5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHMP5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12625	NM_016410.6 Latest version!	Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12872	NM_001195536.1 Latest version!	Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu12625	NM_016410.5	Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CHMP5 ( NM_016410.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057494.3 Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12625
Clone ID Related Accession (Same CDS sequence)	NM_016410.5 , NM_016410.6
Accession Version	NM_016410.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 5 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL356472.17, BC016698.1, BC007457.1 and AI128062.1. On Sep 15, 2010 this sequence version replaced NM_016410.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX342211.2, SRR1803613.232329.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGAACCGAC TCTTCGGGAA AGCGAAACCC AAGGCTCCGC CGCCCAGCCT GACTGACTGC 
ATTGGCACGG TGGACAGTAG AGCAGAATCC ATTGACAAGA AGATTTCTCG ATTGGATGCT 
GAGCTAGTGA AGTATAAGGA TCAGATCAAG AAGATGAGAG AGGGTCCTGC AAAGAATATG 
GTCAAGCAGA AAGCCTTGCG AGTTTTAAAG CAAAAGAGGA TGTATGAGCA GCAGCGGGAC 
AATCTTGCCC AACAGTCATT CAACATGGAA CAAGCCAATT ATACCATCCA GTCTTTGAAG 
GACACCAAGA CCACGGTTGA TGCTATGAAA CTGGGAGTAA AGGAAATGAA GAAGGCATAC 
AAGCAAGTGA AGATCGACCA GATTGAGGAT TTACAAGACC AGCTAGAGGA TATGATGGAA 
GATGCAAATG AAATCCAAGA AGCACTGAGT CGCAGTTATG GCACCCCAGA ACTGGATGAA 
GATGATTTAG AAGCAGAGTT GGATGCACTA GGTGATGAGC TTCTGGCTGA TGAAGACAGT 
TCTTATTTGG ATGAGGCAGC ATCTGCACCT GCAATTCCAG AAGGTGTTCC CACTGATACA 
AAAAACAAGG ATGGAGTTCT GGTGGATGAA TTTGGATTGC CACAGATCCC TGCTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057494.3
CDS	201..860
Translation	MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS

Target ORF information:

RefSeq Version	NM_016410.5
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016410.5

ORF Insert Sequence:

ATGAACCGAC TCTTCGGGAA AGCGAAACCC AAGGCTCCGC CGCCCAGCCT GACTGACTGC 
ATTGGCACGG TGGACAGTAG AGCAGAATCC ATTGACAAGA AGATTTCTCG ATTGGATGCT 
GAGCTAGTGA AGTATAAGGA TCAGATCAAG AAGATGAGAG AGGGTCCTGC AAAGAATATG 
GTCAAGCAGA AAGCCTTGCG AGTTTTAAAG CAAAAGAGGA TGTATGAGCA GCAGCGGGAC 
AATCTTGCCC AACAGTCATT CAACATGGAA CAAGCCAATT ATACCATCCA GTCTTTGAAG 
GACACCAAGA CCACGGTTGA TGCTATGAAA CTGGGAGTAA AGGAAATGAA GAAGGCATAC 
AAGCAAGTGA AGATCGACCA GATTGAGGAT TTACAAGACC AGCTAGAGGA TATGATGGAA 
GATGCAAATG AAATCCAAGA AGCACTGAGT CGCAGTTATG GCACCCCAGA ACTGGATGAA 
GATGATTTAG AAGCAGAGTT GGATGCACTA GGTGATGAGC TTCTGGCTGA TGAAGACAGT 
TCTTATTTGG ATGAGGCAGC ATCTGCACCT GCAATTCCAG AAGGTGTTCC CACTGATACA 
AAAAACAAGG ATGGAGTTCT GGTGGATGAA TTTGGATTGC CACAGATCCC TGCTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP5 ( NM_016410.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_057494.3 Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12625
Clone ID Related Accession (Same CDS sequence)	NM_016410.5 , NM_016410.6
Accession Version	NM_016410.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 5 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC016698.1, BC007457.1, AL356472.17 and AI128062.1. On Nov 23, 2018 this sequence version replaced NM_016410.5. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.91351.1, SRR1803615.136315.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000223500.9/ ENSP00000223500.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACCGAC TCTTCGGGAA AGCGAAACCC AAGGCTCCGC CGCCCAGCCT GACTGACTGC 
ATTGGCACGG TGGACAGTAG AGCAGAATCC ATTGACAAGA AGATTTCTCG ATTGGATGCT 
GAGCTAGTGA AGTATAAGGA TCAGATCAAG AAGATGAGAG AGGGTCCTGC AAAGAATATG 
GTCAAGCAGA AAGCCTTGCG AGTTTTAAAG CAAAAGAGGA TGTATGAGCA GCAGCGGGAC 
AATCTTGCCC AACAGTCATT CAACATGGAA CAAGCCAATT ATACCATCCA GTCTTTGAAG 
GACACCAAGA CCACGGTTGA TGCTATGAAA CTGGGAGTAA AGGAAATGAA GAAGGCATAC 
AAGCAAGTGA AGATCGACCA GATTGAGGAT TTACAAGACC AGCTAGAGGA TATGATGGAA 
GATGCAAATG AAATCCAAGA AGCACTGAGT CGCAGTTATG GCACCCCAGA ACTGGATGAA 
GATGATTTAG AAGCAGAGTT GGATGCACTA GGTGATGAGC TTCTGGCTGA TGAAGACAGT 
TCTTATTTGG ATGAGGCAGC ATCTGCACCT GCAATTCCAG AAGGTGTTCC CACTGATACA 
AAAAACAAGG ATGGAGTTCT GGTGGATGAA TTTGGATTGC CACAGATCCC TGCTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057494.3
CDS	31..690
Translation	MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS

Target ORF information:

RefSeq Version	NM_016410.6
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016410.6

ORF Insert Sequence:

ATGAACCGAC TCTTCGGGAA AGCGAAACCC AAGGCTCCGC CGCCCAGCCT GACTGACTGC 
ATTGGCACGG TGGACAGTAG AGCAGAATCC ATTGACAAGA AGATTTCTCG ATTGGATGCT 
GAGCTAGTGA AGTATAAGGA TCAGATCAAG AAGATGAGAG AGGGTCCTGC AAAGAATATG 
GTCAAGCAGA AAGCCTTGCG AGTTTTAAAG CAAAAGAGGA TGTATGAGCA GCAGCGGGAC 
AATCTTGCCC AACAGTCATT CAACATGGAA CAAGCCAATT ATACCATCCA GTCTTTGAAG 
GACACCAAGA CCACGGTTGA TGCTATGAAA CTGGGAGTAA AGGAAATGAA GAAGGCATAC 
AAGCAAGTGA AGATCGACCA GATTGAGGAT TTACAAGACC AGCTAGAGGA TATGATGGAA 
GATGCAAATG AAATCCAAGA AGCACTGAGT CGCAGTTATG GCACCCCAGA ACTGGATGAA 
GATGATTTAG AAGCAGAGTT GGATGCACTA GGTGATGAGC TTCTGGCTGA TGAAGACAGT 
TCTTATTTGG ATGAGGCAGC ATCTGCACCT GCAATTCCAG AAGGTGTTCC CACTGATACA 
AAAAACAAGG ATGGAGTTCT GGTGGATGAA TTTGGATTGC CACAGATCCC TGCTTCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHMP5 ( NM_001195536.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001182465.1 Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12872
Clone ID Related Accession (Same CDS sequence)	NM_001195536.1
Accession Version	NM_001195536.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	charged multivesicular body protein 5 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL356472.17, AK295744.1 and AI128062.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295744.1, SRR1803612.336393.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGAACCGAC TCTTCGGGAA AGCGAAACCC AAGGCTCCGC CGCCCAGCCT GACTGACTGC 
ATTGGCACGG TGGACAGTAG AGCAGAATCC ATTGACAAGA AGATTTCTCG ATTGGATGCT 
GAGCTAGTGA AGTATAAGGA TCAGATCAAG AAGATGAGAG AGGGTCCTGC AAAGAATATG 
GTCAAGCAGA AAGCCTTGCG AGTTTTAAAG CAAAAGAGGA TGTATGAGCA GCAGCGGGAC 
AATCTTGCCC AACAGTCATT CAACATGGAA CAAGCCAATT ATACCATCCA GTCTTTGAAG 
GACACCAAGA CCACGGTTGA TGCTATGAAA CTGGGAGTAA AGGAAATGAA GAAGGCATAC 
AAGCAAGTGA AGATCGACCA GATTGAGGAT TTACAAGACC AGCTAGAGGA TATGATGGAA 
GATGCAAATG AAATCCAAGA AGCACTGAGT CGCAGTTATG GCACCCCAGA ACTGGATGAA 
GATGATTTAG AAGCAGGATG GAGTTCTGGT GGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001182465.1
CDS	201..716
Translation	MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAGWSSGG

Target ORF information:

RefSeq Version	NM_001195536.1
Organism	Homo sapiens(human)
Definition	Homo sapiens charged multivesicular body protein 5 (CHMP5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001195536.1

ORF Insert Sequence:

ATGAACCGAC TCTTCGGGAA AGCGAAACCC AAGGCTCCGC CGCCCAGCCT GACTGACTGC 
ATTGGCACGG TGGACAGTAG AGCAGAATCC ATTGACAAGA AGATTTCTCG ATTGGATGCT 
GAGCTAGTGA AGTATAAGGA TCAGATCAAG AAGATGAGAG AGGGTCCTGC AAAGAATATG 
GTCAAGCAGA AAGCCTTGCG AGTTTTAAAG CAAAAGAGGA TGTATGAGCA GCAGCGGGAC 
AATCTTGCCC AACAGTCATT CAACATGGAA CAAGCCAATT ATACCATCCA GTCTTTGAAG 
GACACCAAGA CCACGGTTGA TGCTATGAAA CTGGGAGTAA AGGAAATGAA GAAGGCATAC 
AAGCAAGTGA AGATCGACCA GATTGAGGAT TTACAAGACC AGCTAGAGGA TATGATGGAA 
GATGCAAATG AAATCCAAGA AGCACTGAGT CGCAGTTATG GCACCCCAGA ACTGGATGAA 
GATGATTTAG AAGCAGGATG GAGTTCTGGT GGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Charged MVB protein 5 is involved in T-cell receptor signaling.
Experimental & molecular medicine48e206(2016 Jan)
Wi SM,Min Y,Lee KY

Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.
PloS one11(11)e0165420(2016)
Thi?baut R,Esmiol S,Lecine P,Mahfouz B,Hermant A,Nicoletti C,Parnis S,Perroy J,Borg JP,Pascoe L,Hugot JP,Ollendorff V

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

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CHMP5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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