Gene Symbol | UBR5 |
Entrez Gene ID | 51366 |
Full Name | ubiquitin protein ligase E3 component n-recognin 5 |
Synonyms | DD5,EDD,EDD1,HYD |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |