HOOK1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HOOK1
Entrez Gene ID	51361
Full Name	hook microtubule tethering protein 1
Synonyms	HK1
General protein information	Preferred Names hook microtubule tethering protein 1 Names protein Hook homolog 1 h-hook1 hHK1 hook homolog 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p32.1
Summary	This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	607820

mRNA and Protein(s)

mRNA	Protein	Name
XM_006710676.1	XP_006710739.1	protein Hook homolog 1 isoform X3
NM_015888.4	NP_056972.1	protein Hook homolog 1
XM_017001424.1	XP_016856913.1	protein Hook homolog 1 isoform X5
NM_015888.6	NP_056972.1	protein Hook homolog 1
XM_011541562.2	XP_011539864.1	protein Hook homolog 1 isoform X2
XM_011541563.1	XP_011539865.1	protein Hook homolog 1 isoform X4
NM_015888.5	NP_056972.1	protein Hook homolog 1
XM_024447520.1	XP_024303288.1	protein Hook homolog 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	HOOK1	XP_513444.2
Mus musculus (house mouse)	Hook1	NP_084290.1
Canis lupus familiaris (dog)	HOOK1	XP_536692.3
Bos taurus (cattle)	LOC785042	NP_001193799.1
Danio rerio (zebrafish)	hook1	NP_001038663.1
Gallus gallus (chicken)	HOOK1	NP_001006542.1
	HOOK1	XP_001082586.1
Rattus norvegicus (Norway rat)	Hook1	NP_001101416.1
Homo sapiens (human)	HOOK1	NP_056972.1

Gene Ontology
Bibliography

Related articles in PubMed

Detection of heterozygous mutation in hook microtubule-tethering protein 1 in three patients with decapitated and decaudated spermatozoa syndrome.
Chen H, Zhu Y, Zhu Z, Zhi E, Lu K, Wang X, Liu F, Li Z, Xia W
Journal of medical genetics(2018 Jan)

Hook1 inhibits malignancy and epithelial-mesenchymal transition in hepatocellular carcinoma.
Sun X, Zhang Q, Chen W, Hu Q, Lou Y, Fu QH, Zhang JY, Chen YW, Ye LY, Wang Y, Xie SZ, Hu LQ, Liang TB, Bai XL
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(7)1010428317711098(2017 Jul)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hook1 knockdown promoted epithelial-mesenchymal transition and attenuated the sensitivity of hepatocellular carcinoma cells to doxorubicin. In summary, our results indicate that downregulation of Hook1 plays a pivotal role in hepatocellular carcinoma progression via epithelial-mesenchymal transition. Hook1 may be used as a novel marker and therapeutic molecular target in hepatocellular carcinoma
Title: Hook1 inhibits malignancy and epithelial-mesenchymal transition in hepatocellular carcinoma.

Single-molecule motility assays using total internal reflection fluorescence microscopy indicate that both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and higher velocities than the previously characterized dynein activator bicaudal D2 (BICD2).
Title: Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction.

SHP2 positively regulates TGFbeta1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1.
Title: SHP2 positively regulates TGF?1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1.

Hook1, a microtubule- and cargo-tethering protein, recognized the cytoplasmic tail of CD147 to help sort it and CD98 into Rab22a-dependent tubules associated with recycling.
Title: Microtubule-dependent endosomal sorting of clathrin-independent cargo by Hook1.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following HOOK1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HOOK1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30339	NM_015888.6 Latest version!	Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu33490	XM_006710676.1 Latest version!	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu67881	XM_011541563.1 Latest version!	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu90091	XM_017001424.1 Latest version!	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu67880	XM_011541562.2 Latest version!	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu105068	XM_024447520.1 Latest version!	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu30339	NM_015888.4	Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu30339	NM_015888.5	Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HOOK1 ( NM_015888.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056972.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.

Price & Availability↑

CloneID	OHu30339
Clone ID Related Accession (Same CDS sequence)	NM_015888.4 , NM_015888.6 , NM_015888.5
Accession Version	NM_015888.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	protein Hook homolog 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011621.2, AC113175.2, AK027250.1 and AA576610.1. On May 9, 2006 this sequence version replaced NM_015888.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011621.2, SRR1803616.74514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT CACAGAGGTC 
CATGAAGAAT TACAGAAGAA ACAAGAACTC ATTGAAGATC TTCAGCCAGA TATAAATCAA 
AATGTACAAA AGATCAATGA ACTTGAAGCT GCTCTTCAGA AGAAAGATGA AGATATGAAA 
GCAATGGAGG AAAGATATAA AATGTACTTG GAGAAAGCCA GAAATGTAAT AAAAACTTTG 
GATCCCAAGT TAAATCCAGC ATCAGCTGAA ATAATGCTAC TAAGAAAGCA GTTGGCAGAG 
AAAGAGAGAA GAATTGAGAT TCTGGAGAGT GAATGCAAAG TAGCAAAATT CCGTGATTAT 
GAAGAAAAAC TCATTGTTTC TGCGTGGTAT AATAAGAGTC TAGCATTCCA GAAACTGGGG 
ATGGAATCTA GACTTGTGAG CGGCGGTGGT GCCTGCAGTG ACACTGGTGC GTGCACTCCT 
GCGCGGTCTT TCTTAGCGCA GCAACGGCAC ATCACCAACA CCAGAAGAAA TCTCTCTGTT 
AAAGTCCCTG CTACAACATC TGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056972.1
CDS	257..2443
Translation	MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGGGACSDTGACTPARSFLAQQRHITNTRRNLSVKVPATTSD

Target ORF information:

RefSeq Version	NM_015888.4
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015888.4

ORF Insert Sequence:

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT CACAGAGGTC 
CATGAAGAAT TACAGAAGAA ACAAGAACTC ATTGAAGATC TTCAGCCAGA TATAAATCAA 
AATGTACAAA AGATCAATGA ACTTGAAGCT GCTCTTCAGA AGAAAGATGA AGATATGAAA 
GCAATGGAGG AAAGATATAA AATGTACTTG GAGAAAGCCA GAAATGTAAT AAAAACTTTG 
GATCCCAAGT TAAATCCAGC ATCAGCTGAA ATAATGCTAC TAAGAAAGCA GTTGGCAGAG 
AAAGAGAGAA GAATTGAGAT TCTGGAGAGT GAATGCAAAG TAGCAAAATT CCGTGATTAT 
GAAGAAAAAC TCATTGTTTC TGCGTGGTAT AATAAGAGTC TAGCATTCCA GAAACTGGGG 
ATGGAATCTA GACTTGTGAG CGGCGGTGGT GCCTGCAGTG ACACTGGTGC GTGCACTCCT 
GCGCGGTCTT TCTTAGCGCA GCAACGGCAC ATCACCAACA CCAGAAGAAA TCTCTCTGTT 
AAAGTCCCTG CTACAACATC TGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOOK1 ( NM_015888.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_056972.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.

Price & Availability↑

CloneID	OHu30339
Clone ID Related Accession (Same CDS sequence)	NM_015888.4 , NM_015888.6 , NM_015888.5
Accession Version	NM_015888.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Homo sapiens(human)
Product	protein Hook homolog 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL035416.7 and AC113175.2. On Aug 31, 2019 this sequence version replaced NM_015888.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011621.2, AF044923.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT CACAGAGGTC 
CATGAAGAAT TACAGAAGAA ACAAGAACTC ATTGAAGATC TTCAGCCAGA TATAAATCAA 
AATGTACAAA AGATCAATGA ACTTGAAGCT GCTCTTCAGA AGAAAGATGA AGATATGAAA 
GCAATGGAGG AAAGATATAA AATGTACTTG GAGAAAGCCA GAAATGTAAT AAAAACTTTG 
GATCCCAAGT TAAATCCAGC ATCAGCTGAA ATAATGCTAC TAAGAAAGCA GTTGGCAGAG 
AAAGAGAGAA GAATTGAGAT TCTGGAGAGT GAATGCAAAG TAGCAAAATT CCGTGATTAT 
GAAGAAAAAC TCATTGTTTC TGCGTGGTAT AATAAGAGTC TAGCATTCCA GAAACTGGGG 
ATGGAATCTA GACTTGTGAG CGGCGGTGGT GCCTGCAGTG ACACTGGTGC GTGCACTCCT 
GCGCGGTCTT TCTTAGCGCA GCAACGGCAC ATCACCAACA CCAGAAGAAA TCTCTCTGTT 
AAAGTCCCTG CTACAACATC TGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056972.1
CDS	170..2356
Translation	MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGGGACSDTGACTPARSFLAQQRHITNTRRNLSVKVPATTSD

Target ORF information:

RefSeq Version	NM_015888.6
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015888.6

ORF Insert Sequence:

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT CACAGAGGTC 
CATGAAGAAT TACAGAAGAA ACAAGAACTC ATTGAAGATC TTCAGCCAGA TATAAATCAA 
AATGTACAAA AGATCAATGA ACTTGAAGCT GCTCTTCAGA AGAAAGATGA AGATATGAAA 
GCAATGGAGG AAAGATATAA AATGTACTTG GAGAAAGCCA GAAATGTAAT AAAAACTTTG 
GATCCCAAGT TAAATCCAGC ATCAGCTGAA ATAATGCTAC TAAGAAAGCA GTTGGCAGAG 
AAAGAGAGAA GAATTGAGAT TCTGGAGAGT GAATGCAAAG TAGCAAAATT CCGTGATTAT 
GAAGAAAAAC TCATTGTTTC TGCGTGGTAT AATAAGAGTC TAGCATTCCA GAAACTGGGG 
ATGGAATCTA GACTTGTGAG CGGCGGTGGT GCCTGCAGTG ACACTGGTGC GTGCACTCCT 
GCGCGGTCTT TCTTAGCGCA GCAACGGCAC ATCACCAACA CCAGAAGAAA TCTCTCTGTT 
AAAGTCCCTG CTACAACATC TGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOOK1 ( NM_015888.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056972.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.

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CloneID	OHu30339
Clone ID Related Accession (Same CDS sequence)	NM_015888.4 , NM_015888.6 , NM_015888.5
Accession Version	NM_015888.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	protein Hook homolog 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011621.2, AC113175.2, AK027250.1 and AA576610.1. On Nov 23, 2018 this sequence version replaced NM_015888.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.74514.1, SRR1803617.108319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT CACAGAGGTC 
CATGAAGAAT TACAGAAGAA ACAAGAACTC ATTGAAGATC TTCAGCCAGA TATAAATCAA 
AATGTACAAA AGATCAATGA ACTTGAAGCT GCTCTTCAGA AGAAAGATGA AGATATGAAA 
GCAATGGAGG AAAGATATAA AATGTACTTG GAGAAAGCCA GAAATGTAAT AAAAACTTTG 
GATCCCAAGT TAAATCCAGC ATCAGCTGAA ATAATGCTAC TAAGAAAGCA GTTGGCAGAG 
AAAGAGAGAA GAATTGAGAT TCTGGAGAGT GAATGCAAAG TAGCAAAATT CCGTGATTAT 
GAAGAAAAAC TCATTGTTTC TGCGTGGTAT AATAAGAGTC TAGCATTCCA GAAACTGGGG 
ATGGAATCTA GACTTGTGAG CGGCGGTGGT GCCTGCAGTG ACACTGGTGC GTGCACTCCT 
GCGCGGTCTT TCTTAGCGCA GCAACGGCAC ATCACCAACA CCAGAAGAAA TCTCTCTGTT 
AAAGTCCCTG CTACAACATC TGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056972.1
CDS	169..2355
Translation	MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGGGACSDTGACTPARSFLAQQRHITNTRRNLSVKVPATTSD

Target ORF information:

RefSeq Version	NM_015888.5
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015888.5

ORF Insert Sequence:

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT CACAGAGGTC 
CATGAAGAAT TACAGAAGAA ACAAGAACTC ATTGAAGATC TTCAGCCAGA TATAAATCAA 
AATGTACAAA AGATCAATGA ACTTGAAGCT GCTCTTCAGA AGAAAGATGA AGATATGAAA 
GCAATGGAGG AAAGATATAA AATGTACTTG GAGAAAGCCA GAAATGTAAT AAAAACTTTG 
GATCCCAAGT TAAATCCAGC ATCAGCTGAA ATAATGCTAC TAAGAAAGCA GTTGGCAGAG 
AAAGAGAGAA GAATTGAGAT TCTGGAGAGT GAATGCAAAG TAGCAAAATT CCGTGATTAT 
GAAGAAAAAC TCATTGTTTC TGCGTGGTAT AATAAGAGTC TAGCATTCCA GAAACTGGGG 
ATGGAATCTA GACTTGTGAG CGGCGGTGGT GCCTGCAGTG ACACTGGTGC GTGCACTCCT 
GCGCGGTCTT TCTTAGCGCA GCAACGGCAC ATCACCAACA CCAGAAGAAA TCTCTCTGTT 
AAAGTCCCTG CTACAACATC TGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOOK1 ( XM_006710676.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006710739.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu33490
Clone ID Related Accession (Same CDS sequence)	XM_006710676.1
Accession Version	XM_006710676.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein Hook homolog 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTAAAT CGTCTCATGC ATGGCGGCAT CTCATATGTG CATATATACG TCCAGCAAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006710739.1
CDS	197..1879
Translation	MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESKSSHAWRHLICAYIRPAN

Target ORF information:

RefSeq Version	XM_006710676.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006710676.1

ORF Insert Sequence:

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTAAAT CGTCTCATGC ATGGCGGCAT CTCATATGTG CATATATACG TCCAGCAAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOOK1 ( XM_011541563.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539865.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu67881
Clone ID Related Accession (Same CDS sequence)	XM_011541563.1
Accession Version	XM_011541563.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein Hook homolog 1 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTACA AAAGATCAAT GAACTTGAAG CTGCTCTTCA GAAGAAAGAT GAAGATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539865.1
CDS	197..1876
Translation	MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESYKRSMNLKLLFRRKMKI

Target ORF information:

RefSeq Version	XM_011541563.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541563.1

ORF Insert Sequence:

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGAGACTAAT TGAGCAGCGT 
GATACTTTGA AAGAAACAAA TGAAGAGCTT CGATGTTCAC AAGTACAACA GGACCACCTA 
AACCAAACAG ATGCATCTGC TACAAAAAGT TATGAGAATC TTGCTGCTGA GATTATGCCA 
GTGGAATATA GGGAGGTGTT TATTCGACTG CAACATGAAA ATAAGATGCT TCGCTTACAG 
CAAGAAGGCT CTGAGAATGA ACGTATTGAG GAACTTCAGG AGCAGCTAGA ACAGAAACAC 
CGTAAAATGA ATGAACTGGA AACTGAGCAG AGGCTGAGCA AAGAGCGTAT TAGAGAATTG 
CAGCAGCAGA TTGAGGACCT CCAGAAATCT TTACAGGAAC AAGGTTCCAA GTCTGAAGGC 
GAAAGTTACA AAAGATCAAT GAACTTGAAG CTGCTCTTCA GAAGAAAGAT GAAGATATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOOK1 ( XM_017001424.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856913.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X7, mRNA.

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CloneID	OHu90091
Clone ID Related Accession (Same CDS sequence)	XM_017001424.1
Accession Version	XM_017001424.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein Hook homolog 1 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGATTTTCGC TTTGCCCTTG 
GCTTTCAGCA GTTTGACTTT GATATATCCA GGTGTGTGGA TCCTTTTTAG TTTATTGTAC 
TTTGAATTTG TTGAATTTCT TAGAACTGTA GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856913.1
CDS	197..1552
Translation	MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKEIFALPLAFSSLTLIYPGVWILFSLLYFEFVEFLRTVD

Target ORF information:

RefSeq Version	XM_017001424.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001424.1

ORF Insert Sequence:

ATGGAGGAGA CGCAGCCGCC GCCGCAGCCT AAGCTGCCCC TGTGCGACAG CCTCATGATC 
TGGCTGCAGA CATTCAATAC TGCCTCACCT TGTCAAGATG TCAAACAGCT GACTAGTGGA 
GTTGCCATGG CACAAGTTCT TCATCAAATT GATGCAGCTT GGTTTAACGA ATCTTGGTTA 
AGCCGAATTA AAGAGGATGT TGGGGACAAC TGGAGAATAA AGGCCAGTAA TGTAAAGAAG 
GTCCTTCAAG GAATTATGAG TTATTATCAT GAGTTTTTGG GGCAGCAGAT TTCAGAAGCA 
CTTATCCCTG ATTTAAACCA AATAACCGAA TGTTCAGATC CAGTGGAGCT TGGGAGGTTG 
CTCCAGCTTA TTTTAGGTTG TGCGATCAAC TGTGAAAAGA AGCAAGAACA TATTCAAAAT 
ATAATGACAC TGGAAGAGTC TGTTCAACAT GTGGTCATGA CTGCTATTCA AGAGTTGATG 
AGTAAAGAAA TATTGAGCTC TCCTCCAAAT GATGCTGTTG GAGAATTGGA GCAACAGCTT 
AAAAGAGCCT TGGAAGAACT TCAGGAAGCA CTAGCAGAAA AAGAAGAGCT GAGGCAAAGA 
TGTGAAGAAT TGGATATGCA GGTGACTACA CTTCAAGATG AAAAGAATTC ACTGGTTTCT 
GAAAATGAGA TGATGAATGA AAAACTTGAC CAGTTGGATG GCTCTTTTGA TGATCCAAAC 
ACAGTGGTTG CAAAAAAGTA TTTTCATGCA CAATTACAAC TAGAACAATT ACAGGAAGAA 
AACTTCAGGC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAAGA ACTTGAAAAG 
CAGCTAATCG AATTCCAGCA TAGGAATGAT GAATTGACTA GTCTTGCAGA AGAAACAAGA 
GCCCTGAAAG ATGAAATAGA TGTTCTTAGG GCTACCTCTG ATAAAGCAAA TAAACTGGAG 
TCAACAGTTG AGATATATCG TCAGAAGCTA CAAGATCTGA ATGACCTTCG CAAGCAGGTG 
AAAACTTTAC AGGAAACCAA CATGATGTAT ATGCATAATA CAGTCAGCTT AGAAGAAGAA 
TTAAAAAAAG CAAATGCAGC ACGTACACAA TTAGAAACAT ACAAAAGGCA GGTTCAAGAT 
CTTCATGTTA AACTTTCCTC CGAATCCAAG AGGGCAGACA CACTAGCGTT TGAAATGAAG 
CGGCTTGAAG AAAAACATGA AGCTTTACTT AAGGAAAAAG AGATTTTCGC TTTGCCCTTG 
GCTTTCAGCA GTTTGACTTT GATATATCCA GGTGTGTGGA TCCTTTTTAG TTTATTGTAC 
TTTGAATTTG TTGAATTTCT TAGAACTGTA GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOOK1 ( XM_011541562.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539864.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu67880
Clone ID Related Accession (Same CDS sequence)	XM_011541562.2
Accession Version	XM_011541562.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein Hook homolog 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541562.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCAA GGCATTCTTG CAGTGATGCA GCTTGGTTTA ACGAATCTTG GTTAAGCCGA 
ATTAAAGAGG ATGTTGGGGA CAACTGGAGA ATAAAGGCCA GTAATGTAAA GAAGGTCCTT 
CAAGGAATTA TGAGTTATTA TCATGAGTTT TTGGGGCAGC AGATTTCAGA AGCACTTATC 
CCTGATTTAA ACCAAATAAC CGAATGTTCA GATCCAGTGG AGCTTGGGAG GTTGCTCCAG 
CTTATTTTAG GTTGTGCGAT CAACTGTGAA AAGAAGCAAG AACATATTCA AAATATAATG 
ACACTGGAAG AGTCTGTTCA ACATGTGGTC ATGACTGCTA TTCAAGAGTT GATGAGTAAA 
GAAATATTGA GCTCTCCTCC AAATGATGCT GTTGGAGAAT TGGAGCAACA GCTTAAAAGA 
GCCTTGGAAG AACTTCAGGA AGCACTAGCA GAAAAAGAAG AGCTGAGGCA AAGATGTGAA 
GAATTGGATA TGCAGGTGAC TACACTTCAA GATGAAAAGA ATTCACTGGT TTCTGAAAAT 
GAGATGATGA ATGAAAAACT TGACCAGTTG GATGGCTCTT TTGATGATCC AAACACAGTG 
GTTGCAAAAA AGTATTTTCA TGCACAATTA CAACTAGAAC AATTACAGGA AGAAAACTTC 
AGGCTTGAAG CTGCAAAAGA TGATTACCGT GTTCACTGTG AAGAACTTGA AAAGCAGCTA 
ATCGAATTCC AGCATAGGAA TGATGAATTG ACTAGTCTTG CAGAAGAAAC AAGAGCCCTG 
AAAGATGAAA TAGATGTTCT TAGGGCTACC TCTGATAAAG CAAATAAACT GGAGTCAACA 
GTTGAGATAT ATCGTCAGAA GCTACAAGAT CTGAATGACC TTCGCAAGCA GGTGAAAACT 
TTACAGGAAA CCAACATGAT GTATATGCAT AATACAGTCA GCTTAGAAGA AGAATTAAAA 
AAAGCAAATG CAGCACGTAC ACAATTAGAA ACATACAAAA GGCAGGTTCA AGATCTTCAT 
GTTAAACTTT CCTCCGAATC CAAGAGGGCA GACACACTAG CGTTTGAAAT GAAGCGGCTT 
GAAGAAAAAC ATGAAGCTTT ACTTAAGGAA AAAGAGAGAC TAATTGAGCA GCGTGATACT 
TTGAAAGAAA CAAATGAAGA GCTTCGATGT TCACAAGTAC AACAGGACCA CCTAAACCAA 
ACAGATGCAT CTGCTACAAA AAGTTATGAG AATCTTGCTG CTGAGATTAT GCCAGTGGAA 
TATAGGGAGG TGTTTATTCG ACTGCAACAT GAAAATAAGA TGCTTCGCTT ACAGCAAGAA 
GGCTCTGAGA ATGAACGTAT TGAGGAACTT CAGGAGCAGC TAGAACAGAA ACACCGTAAA 
ATGAATGAAC TGGAAACTGA GCAGAGGCTG AGCAAAGAGC GTATTAGAGA ATTGCAGCAG 
CAGATTGAGG ACCTCCAGAA ATCTTTACAG GAACAAGGTT CCAAGTCTGA AGGCGAAAGT 
TCCAGCAAAT TAAAGCAGAA GTTGGAAGCT CATATGGAAA AACTCACAGA GGTCCATGAA 
GAATTACAGA AGAAACAAGA ACTCATTGAA GATCTTCAGC CAGATATAAA TCAAAATGTA 
CAAAAGATCA ATGAACTTGA AGCTGCTCTT CAGAAGAAAG ATGAAGATAT GAAAGCAATG 
GAGGAAAGAT ATAAAATGTA CTTGGAGAAA GCCAGAAATG TAATAAAAAC TTTGGATCCC 
AAGTTAAATC CAGCATCAGC TGAAATAATG CTACTAAGAA AGCAGTTGGC AGAGAAAGAG 
AGAAGAATTG AGATTCTGGA GAGTGAATGC AAAGTAGCAA AATTCCGTGA TTATGAAGAA 
AAACTCATTG TTTCTGCGTG GTATAATAAG AGTCTAGCAT TCCAGAAACT GGGGATGGAA 
TCTAGACTTG TGAGCGGCGG TGGTGCCTGC AGTGACACTG GTGCGTGCAC TCCTGCGCGG 
TCTTTCTTAG CGCAGCAACG GCACATCACC AACACCAGAA GAAATCTCTC TGTTAAAGTC 
CCTGCTACAA CATCTGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539864.1
CDS	353..2413
Translation	MAPRHSCSDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGGGACSDTGACTPARSFLAQQRHITNTRRNLSVKVPATTSD

Target ORF information:

RefSeq Version	XM_011541562.2
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541562.2

ORF Insert Sequence:

ATGGCACCAA GGCATTCTTG CAGTGATGCA GCTTGGTTTA ACGAATCTTG GTTAAGCCGA 
ATTAAAGAGG ATGTTGGGGA CAACTGGAGA ATAAAGGCCA GTAATGTAAA GAAGGTCCTT 
CAAGGAATTA TGAGTTATTA TCATGAGTTT TTGGGGCAGC AGATTTCAGA AGCACTTATC 
CCTGATTTAA ACCAAATAAC CGAATGTTCA GATCCAGTGG AGCTTGGGAG GTTGCTCCAG 
CTTATTTTAG GTTGTGCGAT CAACTGTGAA AAGAAGCAAG AACATATTCA AAATATAATG 
ACACTGGAAG AGTCTGTTCA ACATGTGGTC ATGACTGCTA TTCAAGAGTT GATGAGTAAA 
GAAATATTGA GCTCTCCTCC AAATGATGCT GTTGGAGAAT TGGAGCAACA GCTTAAAAGA 
GCCTTGGAAG AACTTCAGGA AGCACTAGCA GAAAAAGAAG AGCTGAGGCA AAGATGTGAA 
GAATTGGATA TGCAGGTGAC TACACTTCAA GATGAAAAGA ATTCACTGGT TTCTGAAAAT 
GAGATGATGA ATGAAAAACT TGACCAGTTG GATGGCTCTT TTGATGATCC AAACACAGTG 
GTTGCAAAAA AGTATTTTCA TGCACAATTA CAACTAGAAC AATTACAGGA AGAAAACTTC 
AGGCTTGAAG CTGCAAAAGA TGATTACCGT GTTCACTGTG AAGAACTTGA AAAGCAGCTA 
ATCGAATTCC AGCATAGGAA TGATGAATTG ACTAGTCTTG CAGAAGAAAC AAGAGCCCTG 
AAAGATGAAA TAGATGTTCT TAGGGCTACC TCTGATAAAG CAAATAAACT GGAGTCAACA 
GTTGAGATAT ATCGTCAGAA GCTACAAGAT CTGAATGACC TTCGCAAGCA GGTGAAAACT 
TTACAGGAAA CCAACATGAT GTATATGCAT AATACAGTCA GCTTAGAAGA AGAATTAAAA 
AAAGCAAATG CAGCACGTAC ACAATTAGAA ACATACAAAA GGCAGGTTCA AGATCTTCAT 
GTTAAACTTT CCTCCGAATC CAAGAGGGCA GACACACTAG CGTTTGAAAT GAAGCGGCTT 
GAAGAAAAAC ATGAAGCTTT ACTTAAGGAA AAAGAGAGAC TAATTGAGCA GCGTGATACT 
TTGAAAGAAA CAAATGAAGA GCTTCGATGT TCACAAGTAC AACAGGACCA CCTAAACCAA 
ACAGATGCAT CTGCTACAAA AAGTTATGAG AATCTTGCTG CTGAGATTAT GCCAGTGGAA 
TATAGGGAGG TGTTTATTCG ACTGCAACAT GAAAATAAGA TGCTTCGCTT ACAGCAAGAA 
GGCTCTGAGA ATGAACGTAT TGAGGAACTT CAGGAGCAGC TAGAACAGAA ACACCGTAAA 
ATGAATGAAC TGGAAACTGA GCAGAGGCTG AGCAAAGAGC GTATTAGAGA ATTGCAGCAG 
CAGATTGAGG ACCTCCAGAA ATCTTTACAG GAACAAGGTT CCAAGTCTGA AGGCGAAAGT 
TCCAGCAAAT TAAAGCAGAA GTTGGAAGCT CATATGGAAA AACTCACAGA GGTCCATGAA 
GAATTACAGA AGAAACAAGA ACTCATTGAA GATCTTCAGC CAGATATAAA TCAAAATGTA 
CAAAAGATCA ATGAACTTGA AGCTGCTCTT CAGAAGAAAG ATGAAGATAT GAAAGCAATG 
GAGGAAAGAT ATAAAATGTA CTTGGAGAAA GCCAGAAATG TAATAAAAAC TTTGGATCCC 
AAGTTAAATC CAGCATCAGC TGAAATAATG CTACTAAGAA AGCAGTTGGC AGAGAAAGAG 
AGAAGAATTG AGATTCTGGA GAGTGAATGC AAAGTAGCAA AATTCCGTGA TTATGAAGAA 
AAACTCATTG TTTCTGCGTG GTATAATAAG AGTCTAGCAT TCCAGAAACT GGGGATGGAA 
TCTAGACTTG TGAGCGGCGG TGGTGCCTGC AGTGACACTG GTGCGTGCAC TCCTGCGCGG 
TCTTTCTTAG CGCAGCAACG GCACATCACC AACACCAGAA GAAATCTCTC TGTTAAAGTC 
CCTGCTACAA CATCTGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HOOK1 ( XM_024447520.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024303288.1 Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu105068
Clone ID Related Accession (Same CDS sequence)	XM_024447520.1
Accession Version	XM_024447520.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein Hook homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACAAG TTCTTCATCA AATTGATGCA GCTTGGTTTA ACGAATCTTG GTTAAGCCGA 
ATTAAAGAGG ATGTTGGGGA CAACTGGAGA ATAAAGGCCA GTAATGTAAA GAAGGTCCTT 
CAAGGAATTA TGAGTTATTA TCATGAGTTT TTGGGGCAGC AGATTTCAGA AGCACTTATC 
CCTGATTTAA ACCAAATAAC CGAATGTTCA GATCCAGTGG AGCTTGGGAG GTTGCTCCAG 
CTTATTTTAG GTTGTGCGAT CAACTGTGAA AAGAAGCAAG AACATATTCA AAATATAATG 
ACACTGGAAG AGTCTGTTCA ACATGTGGTC ATGACTGCTA TTCAAGAGTT GATGAGTAAA 
GAAATATTGA GCTCTCCTCC AAATGATGCT GTTGGAGAAT TGGAGCAACA GCTTAAAAGA 
GCCTTGGAAG AACTTCAGGA AGCACTAGCA GAAAAAGAAG AGCTGAGGCA AAGATGTGAA 
GAATTGGATA TGCAGGTGAC TACACTTCAA GATGAAAAGA ATTCACTGGT TTCTGAAAAT 
GAGATGATGA ATGAAAAACT TGACCAGTTG GATGGCTCTT TTGATGATCC AAACACAGTG 
GTTGCAAAAA AGTATTTTCA TGCACAATTA CAACTAGAAC AATTACAGGA AGAAAACTTC 
AGGCTTGAAG CTGCAAAAGA TGATTACCGT GTTCACTGTG AAGAACTTGA AAAGCAGCTA 
ATCGAATTCC AGCATAGGAA TGATGAATTG ACTAGTCTTG CAGAAGAAAC AAGAGCCCTG 
AAAGATGAAA TAGATGTTCT TAGGGCTACC TCTGATAAAG CAAATAAACT GGAGTCAACA 
GTTGAGATAT ATCGTCAGAA GCTACAAGAT CTGAATGACC TTCGCAAGCA GGTGAAAACT 
TTACAGGAAA CCAACATGAT GTATATGCAT AATACAGTCA GCTTAGAAGA AGAATTAAAA 
AAAGCAAATG CAGCACGTAC ACAATTAGAA ACATACAAAA GGCAGGTTCA AGATCTTCAT 
GTTAAACTTT CCTCCGAATC CAAGAGGGCA GACACACTAG CGTTTGAAAT GAAGCGGCTT 
GAAGAAAAAC ATGAAGCTTT ACTTAAGGAA AAAGAGAGAC TAATTGAGCA GCGTGATACT 
TTGAAAGAAA CAAATGAAGA GCTTCGATGT TCACAAGTAC AACAGGACCA CCTAAACCAA 
ACAGATGCAT CTGCTACAAA AAGTTATGAG AATCTTGCTG CTGAGATTAT GCCAGTGGAA 
TATAGGGAGG TGTTTATTCG ACTGCAACAT GAAAATAAGA TGCTTCGCTT ACAGCAAGAA 
GGCTCTGAGA ATGAACGTAT TGAGGAACTT CAGGAGCAGC TAGAACAGAA ACACCGTAAA 
ATGAATGAAC TGGAAACTGA GCAGAGGCTG AGCAAAGAGC GTATTAGAGA ATTGCAGCAG 
CAGATTGAGG ACCTCCAGAA ATCTTTACAG GAACAAGGTT CCAAGTCTGA AGGCGAAAGT 
TCCAGCAAAT TAAAGCAGAA GTTGGAAGCT CATATGGAAA AACTCACAGA GGTCCATGAA 
GAATTACAGA AGAAACAAGA ACTCATTGAA GATCTTCAGC CAGATATAAA TCAAAATGTA 
CAAAAGATCA ATGAACTTGA AGCTGCTCTT CAGAAGAAAG ATGAAGATAT GAAAGCAATG 
GAGGAAAGAT ATAAAATGTA CTTGGAGAAA GCCAGAAATG TAATAAAAAC TTTGGATCCC 
AAGTTAAATC CAGCATCAGC TGAAATAATG CTACTAAGAA AGCAGTTGGC AGAGAAAGAG 
AGAAGAATTG AGATTCTGGA GAGTGAATGC AAAGTAGCAA AATTCCGTGA TTATGAAGAA 
AAACTCATTG TTTCTGCGTG GTATAATAAG AGTCTAGCAT TCCAGAAACT GGGGATGGAA 
TCTAGACTTG TGAGCGGCGG TGGTGCCTGC AGTGACACTG GTGCGTGCAC TCCTGCGCGG 
TCTTTCTTAG CGCAGCAACG GCACATCACC AACACCAGAA GAAATCTCTC TGTTAAAGTC 
CCTGCTACAA CATCTGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024303288.1
CDS	952..3012
Translation	MAQVLHQIDAAWFNESWLSRIKEDVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGRLLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGGGACSDTGACTPARSFLAQQRHITNTRRNLSVKVPATTSD

Target ORF information:

RefSeq Version	XM_024447520.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hook microtubule tethering protein 1 (HOOK1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447520.1

ORF Insert Sequence:

ATGGCACAAG TTCTTCATCA AATTGATGCA GCTTGGTTTA ACGAATCTTG GTTAAGCCGA 
ATTAAAGAGG ATGTTGGGGA CAACTGGAGA ATAAAGGCCA GTAATGTAAA GAAGGTCCTT 
CAAGGAATTA TGAGTTATTA TCATGAGTTT TTGGGGCAGC AGATTTCAGA AGCACTTATC 
CCTGATTTAA ACCAAATAAC CGAATGTTCA GATCCAGTGG AGCTTGGGAG GTTGCTCCAG 
CTTATTTTAG GTTGTGCGAT CAACTGTGAA AAGAAGCAAG AACATATTCA AAATATAATG 
ACACTGGAAG AGTCTGTTCA ACATGTGGTC ATGACTGCTA TTCAAGAGTT GATGAGTAAA 
GAAATATTGA GCTCTCCTCC AAATGATGCT GTTGGAGAAT TGGAGCAACA GCTTAAAAGA 
GCCTTGGAAG AACTTCAGGA AGCACTAGCA GAAAAAGAAG AGCTGAGGCA AAGATGTGAA 
GAATTGGATA TGCAGGTGAC TACACTTCAA GATGAAAAGA ATTCACTGGT TTCTGAAAAT 
GAGATGATGA ATGAAAAACT TGACCAGTTG GATGGCTCTT TTGATGATCC AAACACAGTG 
GTTGCAAAAA AGTATTTTCA TGCACAATTA CAACTAGAAC AATTACAGGA AGAAAACTTC 
AGGCTTGAAG CTGCAAAAGA TGATTACCGT GTTCACTGTG AAGAACTTGA AAAGCAGCTA 
ATCGAATTCC AGCATAGGAA TGATGAATTG ACTAGTCTTG CAGAAGAAAC AAGAGCCCTG 
AAAGATGAAA TAGATGTTCT TAGGGCTACC TCTGATAAAG CAAATAAACT GGAGTCAACA 
GTTGAGATAT ATCGTCAGAA GCTACAAGAT CTGAATGACC TTCGCAAGCA GGTGAAAACT 
TTACAGGAAA CCAACATGAT GTATATGCAT AATACAGTCA GCTTAGAAGA AGAATTAAAA 
AAAGCAAATG CAGCACGTAC ACAATTAGAA ACATACAAAA GGCAGGTTCA AGATCTTCAT 
GTTAAACTTT CCTCCGAATC CAAGAGGGCA GACACACTAG CGTTTGAAAT GAAGCGGCTT 
GAAGAAAAAC ATGAAGCTTT ACTTAAGGAA AAAGAGAGAC TAATTGAGCA GCGTGATACT 
TTGAAAGAAA CAAATGAAGA GCTTCGATGT TCACAAGTAC AACAGGACCA CCTAAACCAA 
ACAGATGCAT CTGCTACAAA AAGTTATGAG AATCTTGCTG CTGAGATTAT GCCAGTGGAA 
TATAGGGAGG TGTTTATTCG ACTGCAACAT GAAAATAAGA TGCTTCGCTT ACAGCAAGAA 
GGCTCTGAGA ATGAACGTAT TGAGGAACTT CAGGAGCAGC TAGAACAGAA ACACCGTAAA 
ATGAATGAAC TGGAAACTGA GCAGAGGCTG AGCAAAGAGC GTATTAGAGA ATTGCAGCAG 
CAGATTGAGG ACCTCCAGAA ATCTTTACAG GAACAAGGTT CCAAGTCTGA AGGCGAAAGT 
TCCAGCAAAT TAAAGCAGAA GTTGGAAGCT CATATGGAAA AACTCACAGA GGTCCATGAA 
GAATTACAGA AGAAACAAGA ACTCATTGAA GATCTTCAGC CAGATATAAA TCAAAATGTA 
CAAAAGATCA ATGAACTTGA AGCTGCTCTT CAGAAGAAAG ATGAAGATAT GAAAGCAATG 
GAGGAAAGAT ATAAAATGTA CTTGGAGAAA GCCAGAAATG TAATAAAAAC TTTGGATCCC 
AAGTTAAATC CAGCATCAGC TGAAATAATG CTACTAAGAA AGCAGTTGGC AGAGAAAGAG 
AGAAGAATTG AGATTCTGGA GAGTGAATGC AAAGTAGCAA AATTCCGTGA TTATGAAGAA 
AAACTCATTG TTTCTGCGTG GTATAATAAG AGTCTAGCAT TCCAGAAACT GGGGATGGAA 
TCTAGACTTG TGAGCGGCGG TGGTGCCTGC AGTGACACTG GTGCGTGCAC TCCTGCGCGG 
TCTTTCTTAG CGCAGCAACG GCACATCACC AACACCAGAA GAAATCTCTC TGTTAAAGTC 
CCTGCTACAA CATCTGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Detection of heterozygous mutation in hook microtubule-tethering protein 1 in three patients with decapitated and decaudated spermatozoa syndrome.
Journal of medical genetics(2018 Jan)
Chen H,Zhu Y,Zhu Z,Zhi E,Lu K,Wang X,Liu F,Li Z,Xia W

Hook1 inhibits malignancy and epithelial-mesenchymal transition in hepatocellular carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(7)1010428317711098(2017 Jul)
Sun X,Zhang Q,Chen W,Hu Q,Lou Y,Fu QH,Zhang JY,Chen YW,Ye LY,Wang Y,Xie SZ,Hu LQ,Liang TB,Bai XL

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

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HOOK1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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