TLR8 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TLR8
Entrez Gene ID	51311
Full Name	toll like receptor 8
Synonyms	CD288
General protein information	Preferred Names toll like receptor 8 Names toll-like receptor 8
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: X Map Location: Xp22.2
Summary	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008].
Disorder MIM:	300366

mRNA and Protein(s)

mRNA	Protein	Name
NM_138636.5	NP_619542.1	toll-like receptor 8 isoform 2 precursor
XM_011545529.1	XP_011543831.1	toll-like receptor 8 isoform X1
NM_016610.3	NP_057694.2	toll-like receptor 8 isoform 1
NM_016610.4	NP_057694.2	toll-like receptor 8 isoform 1
XM_011545530.2	XP_011543832.1	toll-like receptor 8 isoform X1
XM_011545530.1	XP_011543832.1	toll-like receptor 8 isoform X1

Pathways from BioSystems

Homologies

	TLR8	NP_001123899.1
Mus musculus (house mouse)	Tlr8	NP_573475.2
Xenopus tropicalis (tropical clawed frog)	LOC100495962	XP_004912402.1
Homo sapiens (human)	TLR8	NP_619542.1
Rattus norvegicus (Norway rat)	Tlr8	NP_001094479.1
Bos taurus (cattle)	TLR8	NP_001029109.1
Danio rerio (zebrafish)	LOC100332583	XP_002665954.3
Xenopus tropicalis (tropical clawed frog)	tlr8	XP_002933859.1
Pan troglodytes (chimpanzee)	TLR8	NP_001123944.1
Canis lupus familiaris (dog)	TLR8	XP_005641176.1
Danio rerio (zebrafish)	tlr8a	XP_001920594.3

Gene Ontology

The following TLR8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28501	NM_016610.4 Latest version!	Homo sapiens toll like receptor 8 (TLR8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu28501	XM_011545530.2 Latest version!	Homo sapiens toll like receptor 8 (TLR8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu28501	XM_011545529.1 Latest version!	Homo sapiens toll like receptor 8 (TLR8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu28645	NM_138636.5 Latest version!	Homo sapiens toll like receptor 8 (TLR8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu28501	NM_016610.3	Homo sapiens toll like receptor 8 (TLR8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu28501	XM_011545530.1	Homo sapiens toll-like receptor 8 (TLR8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TLR8 ( NM_016610.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_057694.2 Homo sapiens toll like receptor 8 (TLR8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28501
Clone ID Related Accession (Same CDS sequence)	XM_011545529.1 , NM_016610.3 , NM_016610.4 , XM_011545530.2 , XM_011545530.1
Accession Version	NM_016610.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-12
Organism	Homo sapiens(human)
Product	toll-like receptor 8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314240.1, AF246971.1, AB445666.1 and AY358296.1. On or before Jun 25, 2014 this sequence version replaced XM_005274543.2, NM_016610.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF246971.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057694.2
CDS	171..3350
Translation	MKESSLQNSSCSLGKETKKENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

Target ORF information:

RefSeq Version	NM_016610.3
Organism	Homo sapiens(human)
Definition	Homo sapiens toll like receptor 8 (TLR8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016610.3

ORF Insert Sequence:

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( NM_016610.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_057694.2 Homo sapiens toll like receptor 8 (TLR8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28501
Clone ID Related Accession (Same CDS sequence)	XM_011545529.1 , NM_016610.3 , NM_016610.4 , XM_011545530.2 , XM_011545530.1
Accession Version	NM_016610.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	toll-like receptor 8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314240.1, AF246971.1, AB445666.1 and AY358296.1. On Jun 2, 2019 this sequence version replaced NM_016610.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF246971.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057694.2
CDS	171..3350
Translation	MKESSLQNSSCSLGKETKKENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

Target ORF information:

RefSeq Version	NM_016610.4
Organism	Homo sapiens(human)
Definition	Homo sapiens toll like receptor 8 (TLR8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016610.4

ORF Insert Sequence:

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_011545529.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543831.1 Homo sapiens toll like receptor 8 (TLR8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu28501
Clone ID Related Accession (Same CDS sequence)	XM_011545529.1 , NM_016610.3 , NM_016610.4 , XM_011545530.2 , XM_011545530.1
Accession Version	XM_011545529.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543831.1
CDS	322..3501
Translation	MKESSLQNSSCSLGKETKKENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

Target ORF information:

RefSeq Version	XM_011545529.1
Organism	Homo sapiens(human)
Definition	Homo sapiens toll like receptor 8 (TLR8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545529.1

ORF Insert Sequence:

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_011545530.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543832.1 Homo sapiens toll like receptor 8 (TLR8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu28501
Clone ID Related Accession (Same CDS sequence)	XM_011545529.1 , NM_016610.3 , NM_016610.4 , XM_011545530.2 , XM_011545530.1
Accession Version	XM_011545530.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	toll-like receptor 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545530.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543832.1
CDS	150..3329
Translation	MKESSLQNSSCSLGKETKKENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

Target ORF information:

RefSeq Version	XM_011545530.2
Organism	Homo sapiens(human)
Definition	Homo sapiens toll like receptor 8 (TLR8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545530.2

ORF Insert Sequence:

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( XM_011545530.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011543832.1 Homo sapiens toll-like receptor 8 (TLR8), transcript variant X2, mRNA.

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CloneID	OHu28501
Clone ID Related Accession (Same CDS sequence)	XM_011545529.1 , NM_016610.3 , NM_016610.4 , XM_011545530.2 , XM_011545530.1
Accession Version	XM_011545530.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3180bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	toll-like receptor 8 isoform X1
Comment

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011543832.1

Translation

MKESSLQNSSCSLGKETKKENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

Target ORF information:

RefSeq Version	XM_011545530.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens toll-like receptor 8 (TLR8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545530.1

ORF Insert Sequence:

ATGAAGGAGT CATCTTTGCA AAATAGCTCC TGCAGCCTGG GAAAGGAGAC TAAAAAGGAA 
AACATGTTCC TTCAGTCGTC AATGCTGACC TGCATTTTCC TGCTAATATC TGGTTCCTGT 
GAGTTATGCG CCGAAGAAAA TTTTTCTAGA AGCTATCCTT GTGATGAGAA AAAGCAAAAT 
GACTCAGTTA TTGCAGAGTG CAGCAATCGT CGACTACAGG AAGTTCCCCA AACGGTGGGC 
AAATATGTGA CAGAACTAGA CCTGTCTGAT AATTTCATCA CACACATAAC GAATGAATCA 
TTTCAAGGGC TGCAAAATCT CACTAAAATA AATCTAAACC ACAACCCCAA TGTACAGCAC 
CAGAACGGAA ATCCCGGTAT ACAATCAAAT GGCTTGAATA TCACAGACGG GGCATTCCTC 
AACCTAAAAA ACCTAAGGGA GTTACTGCTT GAAGACAACC AGTTACCCCA AATACCCTCT 
GGTTTGCCAG AGTCTTTGAC AGAACTTAGT CTAATTCAAA ACAATATATA CAACATAACT 
AAAGAGGGCA TTTCAAGACT TATAAACTTG AAAAATCTCT ATTTGGCCTG GAACTGCTAT 
TTTAACAAAG TTTGCGAGAA AACTAACATA GAAGATGGAG TATTTGAAAC GCTGACAAAT 
TTGGAGTTGC TATCACTATC TTTCAATTCT CTTTCACACG TGCCACCCAA ACTGCCAAGC 
TCCCTACGCA AACTTTTTCT GAGCAACACC CAGATCAAAT ACATTAGTGA AGAAGATTTC 
AAGGGATTGA TAAATTTAAC ATTACTAGAT TTAAGCGGGA ACTGTCCGAG GTGCTTCAAT 
GCCCCATTTC CATGCGTGCC TTGTGATGGT GGTGCTTCAA TTAATATAGA TCGTTTTGCT 
TTTCAAAACT TGACCCAACT TCGATACCTA AACCTCTCTA GCACTTCCCT CAGGAAGATT 
AATGCTGCCT GGTTTAAAAA TATGCCTCAT CTGAAGGTGC TGGATCTTGA ATTCAACTAT 
TTAGTGGGAG AAATAGCCTC TGGGGCATTT TTAACGATGC TGCCCCGCTT AGAAATACTT 
GACTTGTCTT TTAACTATAT AAAGGGGAGT TATCCACAGC ATATTAATAT TTCCAGAAAC 
TTCTCTAAAC TTTTGTCTCT ACGGGCATTG CATTTAAGAG GTTATGTGTT CCAGGAACTC 
AGAGAAGATG ATTTCCAGCC CCTGATGCAG CTTCCAAACT TATCGACTAT CAACTTGGGT 
ATTAATTTTA TTAAGCAAAT CGATTTCAAA CTTTTCCAAA ATTTCTCCAA TCTGGAAATT 
ATTTACTTGT CAGAAAACAG AATATCACCG TTGGTAAAAG ATACCCGGCA GAGTTATGCA 
AATAGTTCCT CTTTTCAACG TCATATCCGG AAACGACGCT CAACAGATTT TGAGTTTGAC 
CCACATTCGA ACTTTTATCA TTTCACCCGT CCTTTAATAA AGCCACAATG TGCTGCTTAT 
GGAAAAGCCT TAGATTTAAG CCTCAACAGT ATTTTCTTCA TTGGGCCAAA CCAATTTGAA 
AATCTTCCTG ACATTGCCTG TTTAAATCTG TCTGCAAATA GCAATGCTCA AGTGTTAAGT 
GGAACTGAAT TTTCAGCCAT TCCTCATGTC AAATATTTGG ATTTGACAAA CAATAGACTA 
GACTTTGATA ATGCTAGTGC TCTTACTGAA TTGTCCGACT TGGAAGTTCT AGATCTCAGC 
TATAATTCAC ACTATTTCAG AATAGCAGGC GTAACACATC ATCTAGAATT TATTCAAAAT 
TTCACAAATC TAAAAGTTTT AAACTTGAGC CACAACAACA TTTATACTTT AACAGATAAG 
TATAACCTGG AAAGCAAGTC CCTGGTAGAA TTAGTTTTCA GTGGCAATCG CCTTGACATT 
TTGTGGAATG ATGATGACAA CAGGTATATC TCCATTTTCA AAGGTCTCAA GAATCTGACA 
CGTCTGGATT TATCCCTTAA TAGGCTGAAG CACATCCCAA ATGAAGCATT CCTTAATTTG 
CCAGCGAGTC TCACTGAACT ACATATAAAT GATAATATGT TAAAGTTTTT TAACTGGACA 
TTACTCCAGC AGTTTCCTCG TCTCGAGTTG CTTGACTTAC GTGGAAACAA ACTACTCTTT 
TTAACTGATA GCCTATCTGA CTTTACATCT TCCCTTCGGA CACTGCTGCT GAGTCATAAC 
AGGATTTCCC ACCTACCCTC TGGCTTTCTT TCTGAAGTCA GTAGTCTGAA GCACCTCGAT 
TTAAGTTCCA ATCTGCTAAA AACAATCAAC AAATCCGCAC TTGAAACTAA GACCACCACC 
AAATTATCTA TGTTGGAACT ACACGGAAAC CCCTTTGAAT GCACCTGTGA CATTGGAGAT 
TTCCGAAGAT GGATGGATGA ACATCTGAAT GTCAAAATTC CCAGACTGGT AGATGTCATT 
TGTGCCAGTC CTGGGGATCA AAGAGGGAAG AGTATTGTGA GTCTGGAGCT AACAACTTGT 
GTTTCAGATG TCACTGCAGT GATATTATTT TTCTTCACGT TCTTTATCAC CACCATGGTT 
ATGTTGGCTG CCCTGGCTCA CCATTTGTTT TACTGGGATG TTTGGTTTAT ATATAATGTG 
TGTTTAGCTA AGGTAAAAGG CTACAGGTCT CTTTCCACAT CCCAAACTTT CTATGATGCT 
TACATTTCTT ATGACACCAA AGATGCCTCT GTTACTGACT GGGTGATAAA TGAGCTGCGC 
TACCACCTTG AAGAGAGCCG AGACAAAAAC GTTCTCCTTT GTCTAGAGGA GAGGGATTGG 
GACCCGGGAT TGGCCATCAT CGACAACCTC ATGCAGAGCA TCAACCAAAG CAAGAAAACA 
GTATTTGTTT TAACCAAAAA ATATGCAAAA AGCTGGAACT TTAAAACAGC TTTTTACTTG 
GCTTTGCAGA GGCTAATGGA TGAGAACATG GATGTGATTA TATTTATCCT GCTGGAGCCA 
GTGTTACAGC ATTCTCAGTA TTTGAGGCTA CGGCAGCGGA TCTGTAAGAG CTCCATCCTC 
CAGTGGCCTG ACAACCCGAA GGCAGAAGGC TTGTTTTGGC AAACTCTGAG AAATGTGGTC 
TTGACTGAAA ATGATTCACG GTATAACAAT ATGTATGTCG ATTCCATTAA GCAATACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TLR8 ( NM_138636.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_619542.1 Homo sapiens toll like receptor 8 (TLR8), transcript variant 2, mRNA.

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CloneID	OHu28645
Clone ID Related Accession (Same CDS sequence)	NM_138636.5
Accession Version	NM_138636.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3126bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	toll-like receptor 8 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005859.1, KC877963.1 and AC139705.4. This sequence is a reference standard in the RefSeqGene project. On Jan 17, 2014 this sequence version replaced NM_138636.4. Transcript Variant: This variant (2) differs in its 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358296.1, BC101074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAAAACA TGTTCCTTCA GTCGTCAATG CTGACCTGCA TTTTCCTGCT AATATCTGGT 
TCCTGTGAGT TATGCGCCGA AGAAAATTTT TCTAGAAGCT ATCCTTGTGA TGAGAAAAAG 
CAAAATGACT CAGTTATTGC AGAGTGCAGC AATCGTCGAC TACAGGAAGT TCCCCAAACG 
GTGGGCAAAT ATGTGACAGA ACTAGACCTG TCTGATAATT TCATCACACA CATAACGAAT 
GAATCATTTC AAGGGCTGCA AAATCTCACT AAAATAAATC TAAACCACAA CCCCAATGTA 
CAGCACCAGA ACGGAAATCC CGGTATACAA TCAAATGGCT TGAATATCAC AGACGGGGCA 
TTCCTCAACC TAAAAAACCT AAGGGAGTTA CTGCTTGAAG ACAACCAGTT ACCCCAAATA 
CCCTCTGGTT TGCCAGAGTC TTTGACAGAA CTTAGTCTAA TTCAAAACAA TATATACAAC 
ATAACTAAAG AGGGCATTTC AAGACTTATA AACTTGAAAA ATCTCTATTT GGCCTGGAAC 
TGCTATTTTA ACAAAGTTTG CGAGAAAACT AACATAGAAG ATGGAGTATT TGAAACGCTG 
ACAAATTTGG AGTTGCTATC ACTATCTTTC AATTCTCTTT CACACGTGCC ACCCAAACTG 
CCAAGCTCCC TACGCAAACT TTTTCTGAGC AACACCCAGA TCAAATACAT TAGTGAAGAA 
GATTTCAAGG GATTGATAAA TTTAACATTA CTAGATTTAA GCGGGAACTG TCCGAGGTGC 
TTCAATGCCC CATTTCCATG CGTGCCTTGT GATGGTGGTG CTTCAATTAA TATAGATCGT 
TTTGCTTTTC AAAACTTGAC CCAACTTCGA TACCTAAACC TCTCTAGCAC TTCCCTCAGG 
AAGATTAATG CTGCCTGGTT TAAAAATATG CCTCATCTGA AGGTGCTGGA TCTTGAATTC 
AACTATTTAG TGGGAGAAAT AGCCTCTGGG GCATTTTTAA CGATGCTGCC CCGCTTAGAA 
ATACTTGACT TGTCTTTTAA CTATATAAAG GGGAGTTATC CACAGCATAT TAATATTTCC 
AGAAACTTCT CTAAACTTTT GTCTCTACGG GCATTGCATT TAAGAGGTTA TGTGTTCCAG 
GAACTCAGAG AAGATGATTT CCAGCCCCTG ATGCAGCTTC CAAACTTATC GACTATCAAC 
TTGGGTATTA ATTTTATTAA GCAAATCGAT TTCAAACTTT TCCAAAATTT CTCCAATCTG 
GAAATTATTT ACTTGTCAGA AAACAGAATA TCACCGTTGG TAAAAGATAC CCGGCAGAGT 
TATGCAAATA GTTCCTCTTT TCAACGTCAT ATCCGGAAAC GACGCTCAAC AGATTTTGAG 
TTTGACCCAC ATTCGAACTT TTATCATTTC ACCCGTCCTT TAATAAAGCC ACAATGTGCT 
GCTTATGGAA AAGCCTTAGA TTTAAGCCTC AACAGTATTT TCTTCATTGG GCCAAACCAA 
TTTGAAAATC TTCCTGACAT TGCCTGTTTA AATCTGTCTG CAAATAGCAA TGCTCAAGTG 
TTAAGTGGAA CTGAATTTTC AGCCATTCCT CATGTCAAAT ATTTGGATTT GACAAACAAT 
AGACTAGACT TTGATAATGC TAGTGCTCTT ACTGAATTGT CCGACTTGGA AGTTCTAGAT 
CTCAGCTATA ATTCACACTA TTTCAGAATA GCAGGCGTAA CACATCATCT AGAATTTATT 
CAAAATTTCA CAAATCTAAA AGTTTTAAAC TTGAGCCACA ACAACATTTA TACTTTAACA 
GATAAGTATA ACCTGGAAAG CAAGTCCCTG GTAGAATTAG TTTTCAGTGG CAATCGCCTT 
GACATTTTGT GGAATGATGA TGACAACAGG TATATCTCCA TTTTCAAAGG TCTCAAGAAT 
CTGACACGTC TGGATTTATC CCTTAATAGG CTGAAGCACA TCCCAAATGA AGCATTCCTT 
AATTTGCCAG CGAGTCTCAC TGAACTACAT ATAAATGATA ATATGTTAAA GTTTTTTAAC 
TGGACATTAC TCCAGCAGTT TCCTCGTCTC GAGTTGCTTG ACTTACGTGG AAACAAACTA 
CTCTTTTTAA CTGATAGCCT ATCTGACTTT ACATCTTCCC TTCGGACACT GCTGCTGAGT 
CATAACAGGA TTTCCCACCT ACCCTCTGGC TTTCTTTCTG AAGTCAGTAG TCTGAAGCAC 
CTCGATTTAA GTTCCAATCT GCTAAAAACA ATCAACAAAT CCGCACTTGA AACTAAGACC 
ACCACCAAAT TATCTATGTT GGAACTACAC GGAAACCCCT TTGAATGCAC CTGTGACATT 
GGAGATTTCC GAAGATGGAT GGATGAACAT CTGAATGTCA AAATTCCCAG ACTGGTAGAT 
GTCATTTGTG CCAGTCCTGG GGATCAAAGA GGGAAGAGTA TTGTGAGTCT GGAGCTAACA 
ACTTGTGTTT CAGATGTCAC TGCAGTGATA TTATTTTTCT TCACGTTCTT TATCACCACC 
ATGGTTATGT TGGCTGCCCT GGCTCACCAT TTGTTTTACT GGGATGTTTG GTTTATATAT 
AATGTGTGTT TAGCTAAGGT AAAAGGCTAC AGGTCTCTTT CCACATCCCA AACTTTCTAT 
GATGCTTACA TTTCTTATGA CACCAAAGAT GCCTCTGTTA CTGACTGGGT GATAAATGAG 
CTGCGCTACC ACCTTGAAGA GAGCCGAGAC AAAAACGTTC TCCTTTGTCT AGAGGAGAGG 
GATTGGGACC CGGGATTGGC CATCATCGAC AACCTCATGC AGAGCATCAA CCAAAGCAAG 
AAAACAGTAT TTGTTTTAAC CAAAAAATAT GCAAAAAGCT GGAACTTTAA AACAGCTTTT 
TACTTGGCTT TGCAGAGGCT AATGGATGAG AACATGGATG TGATTATATT TATCCTGCTG 
GAGCCAGTGT TACAGCATTC TCAGTATTTG AGGCTACGGC AGCGGATCTG TAAGAGCTCC 
ATCCTCCAGT GGCCTGACAA CCCGAAGGCA GAAGGCTTGT TTTGGCAAAC TCTGAGAAAT 
GTGGTCTTGA CTGAAAATGA TTCACGGTAT AACAATATGT ATGTCGATTC CATTAAGCAA 
TACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_619542.1
CDS	88..3213
Translation	MENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

Target ORF information:

RefSeq Version	NM_138636.5
Organism	Homo sapiens(human)
Definition	Homo sapiens toll like receptor 8 (TLR8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138636.5

ORF Insert Sequence:

ATGGAAAACA TGTTCCTTCA GTCGTCAATG CTGACCTGCA TTTTCCTGCT AATATCTGGT 
TCCTGTGAGT TATGCGCCGA AGAAAATTTT TCTAGAAGCT ATCCTTGTGA TGAGAAAAAG 
CAAAATGACT CAGTTATTGC AGAGTGCAGC AATCGTCGAC TACAGGAAGT TCCCCAAACG 
GTGGGCAAAT ATGTGACAGA ACTAGACCTG TCTGATAATT TCATCACACA CATAACGAAT 
GAATCATTTC AAGGGCTGCA AAATCTCACT AAAATAAATC TAAACCACAA CCCCAATGTA 
CAGCACCAGA ACGGAAATCC CGGTATACAA TCAAATGGCT TGAATATCAC AGACGGGGCA 
TTCCTCAACC TAAAAAACCT AAGGGAGTTA CTGCTTGAAG ACAACCAGTT ACCCCAAATA 
CCCTCTGGTT TGCCAGAGTC TTTGACAGAA CTTAGTCTAA TTCAAAACAA TATATACAAC 
ATAACTAAAG AGGGCATTTC AAGACTTATA AACTTGAAAA ATCTCTATTT GGCCTGGAAC 
TGCTATTTTA ACAAAGTTTG CGAGAAAACT AACATAGAAG ATGGAGTATT TGAAACGCTG 
ACAAATTTGG AGTTGCTATC ACTATCTTTC AATTCTCTTT CACACGTGCC ACCCAAACTG 
CCAAGCTCCC TACGCAAACT TTTTCTGAGC AACACCCAGA TCAAATACAT TAGTGAAGAA 
GATTTCAAGG GATTGATAAA TTTAACATTA CTAGATTTAA GCGGGAACTG TCCGAGGTGC 
TTCAATGCCC CATTTCCATG CGTGCCTTGT GATGGTGGTG CTTCAATTAA TATAGATCGT 
TTTGCTTTTC AAAACTTGAC CCAACTTCGA TACCTAAACC TCTCTAGCAC TTCCCTCAGG 
AAGATTAATG CTGCCTGGTT TAAAAATATG CCTCATCTGA AGGTGCTGGA TCTTGAATTC 
AACTATTTAG TGGGAGAAAT AGCCTCTGGG GCATTTTTAA CGATGCTGCC CCGCTTAGAA 
ATACTTGACT TGTCTTTTAA CTATATAAAG GGGAGTTATC CACAGCATAT TAATATTTCC 
AGAAACTTCT CTAAACTTTT GTCTCTACGG GCATTGCATT TAAGAGGTTA TGTGTTCCAG 
GAACTCAGAG AAGATGATTT CCAGCCCCTG ATGCAGCTTC CAAACTTATC GACTATCAAC 
TTGGGTATTA ATTTTATTAA GCAAATCGAT TTCAAACTTT TCCAAAATTT CTCCAATCTG 
GAAATTATTT ACTTGTCAGA AAACAGAATA TCACCGTTGG TAAAAGATAC CCGGCAGAGT 
TATGCAAATA GTTCCTCTTT TCAACGTCAT ATCCGGAAAC GACGCTCAAC AGATTTTGAG 
TTTGACCCAC ATTCGAACTT TTATCATTTC ACCCGTCCTT TAATAAAGCC ACAATGTGCT 
GCTTATGGAA AAGCCTTAGA TTTAAGCCTC AACAGTATTT TCTTCATTGG GCCAAACCAA 
TTTGAAAATC TTCCTGACAT TGCCTGTTTA AATCTGTCTG CAAATAGCAA TGCTCAAGTG 
TTAAGTGGAA CTGAATTTTC AGCCATTCCT CATGTCAAAT ATTTGGATTT GACAAACAAT 
AGACTAGACT TTGATAATGC TAGTGCTCTT ACTGAATTGT CCGACTTGGA AGTTCTAGAT 
CTCAGCTATA ATTCACACTA TTTCAGAATA GCAGGCGTAA CACATCATCT AGAATTTATT 
CAAAATTTCA CAAATCTAAA AGTTTTAAAC TTGAGCCACA ACAACATTTA TACTTTAACA 
GATAAGTATA ACCTGGAAAG CAAGTCCCTG GTAGAATTAG TTTTCAGTGG CAATCGCCTT 
GACATTTTGT GGAATGATGA TGACAACAGG TATATCTCCA TTTTCAAAGG TCTCAAGAAT 
CTGACACGTC TGGATTTATC CCTTAATAGG CTGAAGCACA TCCCAAATGA AGCATTCCTT 
AATTTGCCAG CGAGTCTCAC TGAACTACAT ATAAATGATA ATATGTTAAA GTTTTTTAAC 
TGGACATTAC TCCAGCAGTT TCCTCGTCTC GAGTTGCTTG ACTTACGTGG AAACAAACTA 
CTCTTTTTAA CTGATAGCCT ATCTGACTTT ACATCTTCCC TTCGGACACT GCTGCTGAGT 
CATAACAGGA TTTCCCACCT ACCCTCTGGC TTTCTTTCTG AAGTCAGTAG TCTGAAGCAC 
CTCGATTTAA GTTCCAATCT GCTAAAAACA ATCAACAAAT CCGCACTTGA AACTAAGACC 
ACCACCAAAT TATCTATGTT GGAACTACAC GGAAACCCCT TTGAATGCAC CTGTGACATT 
GGAGATTTCC GAAGATGGAT GGATGAACAT CTGAATGTCA AAATTCCCAG ACTGGTAGAT 
GTCATTTGTG CCAGTCCTGG GGATCAAAGA GGGAAGAGTA TTGTGAGTCT GGAGCTAACA 
ACTTGTGTTT CAGATGTCAC TGCAGTGATA TTATTTTTCT TCACGTTCTT TATCACCACC 
ATGGTTATGT TGGCTGCCCT GGCTCACCAT TTGTTTTACT GGGATGTTTG GTTTATATAT 
AATGTGTGTT TAGCTAAGGT AAAAGGCTAC AGGTCTCTTT CCACATCCCA AACTTTCTAT 
GATGCTTACA TTTCTTATGA CACCAAAGAT GCCTCTGTTA CTGACTGGGT GATAAATGAG 
CTGCGCTACC ACCTTGAAGA GAGCCGAGAC AAAAACGTTC TCCTTTGTCT AGAGGAGAGG 
GATTGGGACC CGGGATTGGC CATCATCGAC AACCTCATGC AGAGCATCAA CCAAAGCAAG 
AAAACAGTAT TTGTTTTAAC CAAAAAATAT GCAAAAAGCT GGAACTTTAA AACAGCTTTT 
TACTTGGCTT TGCAGAGGCT AATGGATGAG AACATGGATG TGATTATATT TATCCTGCTG 
GAGCCAGTGT TACAGCATTC TCAGTATTTG AGGCTACGGC AGCGGATCTG TAAGAGCTCC 
ATCCTCCAGT GGCCTGACAA CCCGAAGGCA GAAGGCTTGT TTTGGCAAAC TCTGAGAAAT 
GTGGTCTTGA CTGAAAATGA TTCACGGTAT AACAATATGT ATGTCGATTC CATTAAGCAA 
TACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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TLR8 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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