PAIP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PAIP2
Entrez Gene ID	51247
Full Name	poly(A) binding protein interacting protein 2
Synonyms	PAIP-2,PAIP2A
General protein information	Preferred Names poly(A) binding protein interacting protein 2 Names polyadenylate-binding protein-interacting protein 2 PABC1-interacting protein 2 PABP-interacting protein 2 polyA-binding protein-interacting protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q31.2
Disorder MIM:	605604

mRNA and Protein(s)

mRNA	Protein	Name
XM_017009522.1	XP_016865011.1	polyadenylate-binding protein-interacting protein 2 isoform X1
XM_017009523.2	XP_016865012.1	polyadenylate-binding protein-interacting protein 2 isoform X1
NM_001033112.2	NP_001028284.1	polyadenylate-binding protein-interacting protein 2
NM_016480.4	NP_057564.3	polyadenylate-binding protein-interacting protein 2
XM_011543428.1	XP_011541730.1	polyadenylate-binding protein-interacting protein 2 isoform X1
XM_017009523.1	XP_016865012.1	polyadenylate-binding protein-interacting protein 2 isoform X1
NM_016480.5	NP_057564.3	polyadenylate-binding protein-interacting protein 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PAIP2	NP_001029808.1
Homo sapiens (human)	PAIP2	NP_057564.3
Rattus norvegicus (Norway rat)	Paip2	NP_001014170.1
Pan troglodytes (chimpanzee)	PAIP2	XP_517964.1
Canis lupus familiaris (dog)	PAIP2	XP_535206.2
Gallus gallus (chicken)	PAIP2	NP_001007833.1
	PAIP2	XP_001082151.1
Mus musculus (house mouse)	Paip2	NP_080696.1

Gene Ontology
Bibliography

Related articles in PubMed

A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication.
McKinney C, Yu D, Mohr I
Genes & development27(16)1809-20(2013 Aug)

Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.
Graubert TA, Payton MA, Shao J, Walgren RA, Monahan RS, Frater JL, Walshauser MA, Martin MG, Kasai Y, Walter MJ
PloS one4(2)e4583(2009)

Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B.
Berlanga JJ, Baass A, Sonenberg N
RNA (New York, N.Y.)12(8)1556-68(2006 Aug)

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2.
Yoshida M, Yoshida K, Kozlov G, Lim NS, De Crescenzo G, Pang Z, Berlanga JJ, Kahvejian A, Gehring K, Wing SS, Sonenberg N
The EMBO journal25(9)1934-44(2006 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Paip2 is a host antiviral restriction factor antagonized by PABP accumulation in HCMV-infected cells
Title: A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication.

Observational study of gene-disease association. (HuGE Navigator)
Title: Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.

The turnover of Paip2 in the cell is mediated by EDD and is regulated by PABP.
Title: Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2.

PAIP2 is a crucial regulator of VEGF mRNA and has a role in regulating angiogenesis
Title: Poly(A)-binding protein-interacting protein 2, a strong regulator of vascular endothelial growth factor mRNA.

Role of PAIP2 in modulation of GLUT5 mRNA stability.
Title: Fructose modulates GLUT5 mRNA stability in differentiated Caco-2 cells: role of cAMP-signalling pathway and PABP (polyadenylated-binding protein)-interacting protein (Paip) 2.

The following PAIP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAIP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10013	NM_001033112.2 Latest version!	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10013	NM_016480.5 Latest version!	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10013	XM_017009522.1 Latest version!	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10013	XM_017009523.2 Latest version!	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10013	XM_011543428.1 Latest version!	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu10013	XM_017009523.1	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10013	NM_016480.4	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PAIP2 ( NM_001033112.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001028284.1 Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10013
Clone ID Related Accession (Same CDS sequence)	XM_017009522.1 , XM_017009523.2 , NM_001033112.2 , NM_016480.4 , XM_011543428.1 , XM_017009523.1 , NM_016480.5
Accession Version	NM_001033112.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein-interacting protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB448759.1, BC062718.1, BC039337.1 and BU732743.1. On Dec 13, 2013 this sequence version replaced NM_001033112.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279830.4046.1, BC062718.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028284.1
CDS	210..593
Translation	MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Target ORF information:

RefSeq Version	NM_001033112.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033112.2

ORF Insert Sequence:

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAIP2 ( NM_016480.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057564.3 Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10013
Clone ID Related Accession (Same CDS sequence)	XM_017009522.1 , XM_017009523.2 , NM_001033112.2 , NM_016480.4 , XM_011543428.1 , XM_017009523.1 , NM_016480.5
Accession Version	NM_016480.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein-interacting protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI552800.1, BC039337.1 and BU732743.1. On Dec 13, 2013 this sequence version replaced NM_016480.3. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.443630.1, SRR1803615.327429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057564.3
CDS	176..559
Translation	MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Target ORF information:

RefSeq Version	NM_016480.4
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016480.4

ORF Insert Sequence:

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAIP2 ( NM_016480.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057564.3 Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10013
Clone ID Related Accession (Same CDS sequence)	XM_017009522.1 , XM_017009523.2 , NM_001033112.2 , NM_016480.4 , XM_011543428.1 , XM_017009523.1 , NM_016480.5
Accession Version	NM_016480.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein-interacting protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI552800.1, BC039337.1 and BU732743.1. On Nov 23, 2018 this sequence version replaced NM_016480.4. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.532927.1, SRR1660809.145436.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265192.9/ ENSP00000265192.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057564.3
CDS	154..537
Translation	MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Target ORF information:

RefSeq Version	NM_016480.5
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016480.5

ORF Insert Sequence:

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAIP2 ( XM_017009522.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865011.1 Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu10013
Clone ID Related Accession (Same CDS sequence)	XM_017009522.1 , XM_017009523.2 , NM_001033112.2 , NM_016480.4 , XM_011543428.1 , XM_017009523.1 , NM_016480.5
Accession Version	XM_017009522.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein-interacting protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865011.1
CDS	1584..1967
Translation	MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Target ORF information:

RefSeq Version	XM_017009522.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009522.1

ORF Insert Sequence:

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAIP2 ( XM_017009523.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865012.1 Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu10013
Clone ID Related Accession (Same CDS sequence)	XM_017009522.1 , XM_017009523.2 , NM_001033112.2 , NM_016480.4 , XM_011543428.1 , XM_017009523.1 , NM_016480.5
Accession Version	XM_017009523.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein-interacting protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017009523.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865012.1
CDS	160..543
Translation	MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Target ORF information:

RefSeq Version	XM_017009523.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009523.2

ORF Insert Sequence:

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAIP2 ( XM_011543428.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541730.1 Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu10013
Clone ID Related Accession (Same CDS sequence)	XM_017009522.1 , XM_017009523.2 , NM_001033112.2 , NM_016480.4 , XM_011543428.1 , XM_017009523.1 , NM_016480.5
Accession Version	XM_011543428.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein-interacting protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541730.1
CDS	258..641
Translation	MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Target ORF information:

RefSeq Version	XM_011543428.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011543428.1

ORF Insert Sequence:

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAIP2 ( XM_017009523.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865012.1 Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu10013
Clone ID Related Accession (Same CDS sequence)	XM_017009522.1 , XM_017009523.2 , NM_001033112.2 , NM_016480.4 , XM_011543428.1 , XM_017009523.1 , NM_016480.5
Accession Version	XM_017009523.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	polyadenylate-binding protein-interacting protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865012.1
CDS	129..512
Translation	MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Target ORF information:

RefSeq Version	XM_017009523.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) binding protein interacting protein 2 (PAIP2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009523.1

ORF Insert Sequence:

ATGAAAGATC CAAGTCGCAG CAGTACTAGC CCAAGCATCA TCAATGAAGA TGTGATTATT 
AACGGTCATT CTCATGAAGA TGACAATCCA TTTGCAGAGT ACATGTGGAT GGAAAATGAA 
GAAGAATTCA ACAGACAAAT AGAAGAGGAG TTATGGGAAG AAGAATTTAT TGAACGCTGT 
TTCCAAGAAA TGCTGGAAGA GGAAGAAGAG CATGAATGGT TTATTCCAGC TCGAGATCTC 
CCACAAACTA TGGACCAAAT CCAAGACCAG TTTAATGACC TTGTTATCAG TGATGGCTCT 
TCTCTGGAAG ATCTTGTGGT CAAGAGCAAT CTGAATCCAA ATGCAAAGGA GTTTGTTCCT 
GGGGTGAAGT ACGGAAATAT TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication.
Genes & development27(16)1809-20(2013 Aug)
McKinney C,Yu D,Mohr I

Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.
PloS one4(2)e4583(2009)
Graubert TA,Payton MA,Shao J,Walgren RA,Monahan RS,Frater JL,Walshauser MA,Martin MG,Kasai Y,Walter MJ

Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B.
RNA (New York, N.Y.)12(8)1556-68(2006 Aug)
Berlanga JJ,Baass A,Sonenberg N

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2.
The EMBO journal25(9)1934-44(2006 May)
Yoshida M,Yoshida K,Kozlov G,Lim NS,De Crescenzo G,Pang Z,Berlanga JJ,Kahvejian A,Gehring K,Wing SS,Sonenberg N

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PAIP2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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