CKLF cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CKLF
Entrez Gene ID	51192
Full Name	chemokine like factor
Synonyms	C32,CKLF1,CKLF2,CKLF3,CKLF4,HSPC224,UCK-1
General protein information	Preferred Names chemokine like factor Names chemokine-like factor chemokine-like factor 1 chemokine-like factor 2 chemokine-like factor 3 chemokine-like factor 4 transmembrane proteolipid
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q21
Summary	The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011].
Disorder MIM:	616074

mRNA and Protein(s)

mRNA	Protein	Name
NM_016951.3	NP_058647.1	chemokine-like factor isoform a
NM_181641.2	NP_857592.1	chemokine-like factor isoform d
NM_016326.3	NP_057410.1	chemokine-like factor isoform c
NM_016951.4	NP_058647.1	chemokine-like factor isoform a
NM_181640.2	NP_857591.1	chemokine-like factor isoform b
NM_001040138.2	NP_001035228.1	chemokine-like factor isoform e

Pathways from BioSystems

Homologies

Homo sapiens (human)	CKLF	NP_058647.1
Mus musculus (house mouse)	Cklf	NP_083571.1
Rattus norvegicus (Norway rat)	Cklf	NP_620811.1
Canis lupus familiaris (dog)	CKLF	NP_001239269.1
Pan troglodytes (chimpanzee)	CKLF	XP_001158562.1

Gene Ontology
Bibliography

Related articles in PubMed

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer.
Dunne PD, O'Reilly PG, Coleman HG, Gray RT, Longley DB, Johnston PG, Salto-Tellez M, Lawler M, McArt DG
Oncotarget7(24)36632-36644(2016 Jun)

Chemokine-Like Factor 1 (CKLF-1) is Overexpressed in Keloid Patients: A Potential Indicating Factor for Keloid-Predisposed Individuals.
Zhang M, Xu Y, Liu Y, Cheng Y, Zhao P, Liu H, Wang Y, Ma X
Medicine95(11)e3082(2016 Mar)

Distinct expression of chemokine-like factor 1 in synovium of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Tao K, Tang X, Wang B, Li RJ, Zhang BQ, Lin JH, Li H
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban36(1)70-6(2016 Feb)

Chemokine-like factor 1-derived C-terminal peptides induce the proliferation of dermal microvascular endothelial cells in psoriasis.
Tan Y, Wang Y, Li L, Xia J, Peng S, He Y
PloS one10(4)e0125073(2015)

Chemokine-like factor 1 (CLFK1) is over-expressed in patients with atopic dermatitis.
Yang GY, Chen X, Sun YC, Ma CL, Qian G
International journal of biological sciences9(8)759-65(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that leukocyte-infiltrate derived chemokine-like factor (CKLF) expression is a candidate biomarker of favorable prognosis.
Title: Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer.

expression elevated in the skin of keloid patients
Title: Chemokine-Like Factor 1 (CKLF-1) is Overexpressed in Keloid Patients: A Potential Indicating Factor for Keloid-Predisposed Individuals.

CKLF1 expression was up-regulated in synovim from rheumatoid arthritis and ankylosing spondylitis patients.
Title: Distinct expression of chemokine-like factor 1 in synovium of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

role in the pathogenesis of psoriasis by promoting the proliferation of microvascular endothelial cells
Title: Chemokine-like factor 1-derived C-terminal peptides induce the proliferation of dermal microvascular endothelial cells in psoriasis.

Chemokine-like factor 1 is over-expressed in patients with atopic dermatitis.
Title: Chemokine-like factor 1 (CLFK1) is over-expressed in patients with atopic dermatitis.

The following CKLF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CKLF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14086	NM_181640.2 Latest version!	Homo sapiens chemokine like factor (CKLF), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14143	NM_016951.4 Latest version!	Homo sapiens chemokine like factor (CKLF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14100	NM_181641.2 Latest version!	Homo sapiens chemokine like factor (CKLF), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu14170	NM_016326.3 Latest version!	Homo sapiens chemokine like factor (CKLF), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu14175	NM_001040138.2 Latest version!	Homo sapiens chemokine like factor (CKLF), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu14143	NM_016951.3	Homo sapiens chemokine like factor (CKLF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CKLF ( NM_181640.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_857591.1 Homo sapiens chemokine like factor (CKLF), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14086
Clone ID Related Accession (Same CDS sequence)	NM_181640.2
Accession Version	NM_181640.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	chemokine-like factor isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA113473.1, AF096895.2 and BU189908.1. On Feb 3, 2011 this sequence version replaced NM_181640.1. Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (b), also known as an isoform CKLF1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK290307.1, DA441117.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGA TATTATCAAC TCACTGGTAA CAACAGTATT CATGCTCATC 
GTATCTGTGT TGGCACTGAT ACCAGAAACC ACAACATTGA CAGTTGGTGG AGGGGTGTTT 
GCACTTGTGA CAGCAGTATG CTGTCTTGCC GACGGGGCCC TTATTTACCG GAAGCTTCTG 
TTCAATCCCA GCGGTCCTTA CCAGAAAAAG CCTGTGCATG AAAAAAAAGA AGTTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_857591.1
CDS	154..453
Translation	MDNVQPKIKHRPFCFSVKGHVKMLRLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL

Target ORF information:

RefSeq Version	NM_181640.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chemokine like factor (CKLF), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181640.2

ORF Insert Sequence:

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGA TATTATCAAC TCACTGGTAA CAACAGTATT CATGCTCATC 
GTATCTGTGT TGGCACTGAT ACCAGAAACC ACAACATTGA CAGTTGGTGG AGGGGTGTTT 
GCACTTGTGA CAGCAGTATG CTGTCTTGCC GACGGGGCCC TTATTTACCG GAAGCTTCTG 
TTCAATCCCA GCGGTCCTTA CCAGAAAAAG CCTGTGCATG AAAAAAAAGA AGTTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKLF ( NM_016951.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_058647.1 Homo sapiens chemokine like factor (CKLF), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14143
Clone ID Related Accession (Same CDS sequence)	NM_016951.3 , NM_016951.4
Accession Version	NM_016951.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-04
Organism	Homo sapiens(human)
Product	chemokine-like factor isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA113473.1, AF135380.2 and BU189908.1. On Feb 3, 2011 this sequence version replaced NM_016951.2. Transcript Variant: This variant (1) represents the longest transcript, and encodes the longest isoform (a), also known as an isoform CKLF2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.294775.1, DR005690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGAT 
ATTATCAACT CACTGGTAAC AACAGTATTC ATGCTCATCG TATCTGTGTT GGCACTGATA 
CCAGAAACCA CAACATTGAC AGTTGGTGGA GGGGTGTTTG CACTTGTGAC AGCAGTATGC 
TGTCTTGCCG ACGGGGCCCT TATTTACCGG AAGCTTCTGT TCAATCCCAG CGGTCCTTAC 
CAGAAAAAGC CTGTGCATGA AAAAAAAGAA GTTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058647.1
CDS	154..612
Translation	MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL

Target ORF information:

RefSeq Version	NM_016951.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chemokine like factor (CKLF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016951.3

ORF Insert Sequence:

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGAT 
ATTATCAACT CACTGGTAAC AACAGTATTC ATGCTCATCG TATCTGTGTT GGCACTGATA 
CCAGAAACCA CAACATTGAC AGTTGGTGGA GGGGTGTTTG CACTTGTGAC AGCAGTATGC 
TGTCTTGCCG ACGGGGCCCT TATTTACCGG AAGCTTCTGT TCAATCCCAG CGGTCCTTAC 
CAGAAAAAGC CTGTGCATGA AAAAAAAGAA GTTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKLF ( NM_016951.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_058647.1 Homo sapiens chemokine like factor (CKLF), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14143
Clone ID Related Accession (Same CDS sequence)	NM_016951.3 , NM_016951.4
Accession Version	NM_016951.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	chemokine-like factor isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF135380.2. On Nov 30, 2019 this sequence version replaced NM_016951.3. Transcript Variant: This variant (1) represents the longest transcript, and encodes the longest isoform (a), also known as an isoform CKLF2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI561562.1, AF135380.2 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGAT 
ATTATCAACT CACTGGTAAC AACAGTATTC ATGCTCATCG TATCTGTGTT GGCACTGATA 
CCAGAAACCA CAACATTGAC AGTTGGTGGA GGGGTGTTTG CACTTGTGAC AGCAGTATGC 
TGTCTTGCCG ACGGGGCCCT TATTTACCGG AAGCTTCTGT TCAATCCCAG CGGTCCTTAC 
CAGAAAAAGC CTGTGCATGA AAAAAAAGAA GTTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058647.1
CDS	141..599
Translation	MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL

Target ORF information:

RefSeq Version	NM_016951.4
Organism	Homo sapiens(human)
Definition	Homo sapiens chemokine like factor (CKLF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016951.4

ORF Insert Sequence:

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGAT 
ATTATCAACT CACTGGTAAC AACAGTATTC ATGCTCATCG TATCTGTGTT GGCACTGATA 
CCAGAAACCA CAACATTGAC AGTTGGTGGA GGGGTGTTTG CACTTGTGAC AGCAGTATGC 
TGTCTTGCCG ACGGGGCCCT TATTTACCGG AAGCTTCTGT TCAATCCCAG CGGTCCTTAC 
CAGAAAAAGC CTGTGCATGA AAAAAAAGAA GTTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKLF ( NM_181641.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_857592.1 Homo sapiens chemokine like factor (CKLF), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu14100
Clone ID Related Accession (Same CDS sequence)	NM_181641.2
Accession Version	NM_181641.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	chemokine-like factor isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA113473.1, AF145216.2 and BU189908.1. On Feb 3, 2011 this sequence version replaced NM_181641.1. Transcript Variant: This variant (4) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter isoform (d), also known as an isoform CKLF4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.299592.1, AF145216.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGTG 
TTTGCACTTG TGACAGCAGT ATGCTGTCTT GCCGACGGGG CCCTTATTTA CCGGAAGCTT 
CTGTTCAATC CCAGCGGTCC TTACCAGAAA AAGCCTGTGC ATGAAAAAAA AGAAGTTTTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_857592.1
CDS	154..516
Translation	MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL

Target ORF information:

RefSeq Version	NM_181641.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chemokine like factor (CKLF), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181641.2

ORF Insert Sequence:

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGTG 
TTTGCACTTG TGACAGCAGT ATGCTGTCTT GCCGACGGGG CCCTTATTTA CCGGAAGCTT 
CTGTTCAATC CCAGCGGTCC TTACCAGAAA AAGCCTGTGC ATGAAAAAAA AGAAGTTTTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKLF ( NM_016326.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057410.1 Homo sapiens chemokine like factor (CKLF), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu14170
Clone ID Related Accession (Same CDS sequence)	NM_016326.3
Accession Version	NM_016326.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 204bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-04
Organism	Homo sapiens(human)
Product	chemokine-like factor isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA113473.1, AF135381.2 and BU189908.1. On Feb 3, 2011 this sequence version replaced NM_016326.2. Transcript Variant: This variant (3) lacks two an in-frame exons in the coding region, compared to variant 1. It encodes a shorter isoform (c), also known as an isoform CKL3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF135381.2, BU589395.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGT GTTTGCACTT GTGACAGCAG TATGCTGTCT TGCCGACGGG 
GCCCTTATTT ACCGGAAGCT TCTGTTCAAT CCCAGCGGTC CTTACCAGAA AAAGCCTGTG 
CATGAAAAAA AAGAAGTTTT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057410.1
CDS	154..357
Translation	MDNVQPKIKHRPFCFSVKGHVKMLRLVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL

Target ORF information:

RefSeq Version	NM_016326.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chemokine like factor (CKLF), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016326.3

ORF Insert Sequence:

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGT GTTTGCACTT GTGACAGCAG TATGCTGTCT TGCCGACGGG 
GCCCTTATTT ACCGGAAGCT TCTGTTCAAT CCCAGCGGTC CTTACCAGAA AAAGCCTGTG 
CATGAAAAAA AAGAAGTTTT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CKLF ( NM_001040138.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035228.1 Homo sapiens chemokine like factor (CKLF), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu14175
Clone ID Related Accession (Same CDS sequence)	NM_001040138.2
Accession Version	NM_001040138.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	chemokine-like factor isoform e
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA113473.1, DA804889.1 and BU189908.1. On Feb 12, 2011 this sequence version replaced NM_001040138.1. Transcript Variant: This variant (5) differs in the coding region and 3' UTR, compared to variant 1. The encoded isoform (e) is shorter and contains a unique C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA804889.1, DB149949.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGAT 
ATTATCAACT CACTGGTAAC AACAGTATTC ATGCTCATCG TATCTGTGTT GGCACTGATA 
CCAGAAACCA CAACATTGAC AGTTGGTGGA GGGTTATTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035228.1
CDS	154..495
Translation	MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGLF

Target ORF information:

RefSeq Version	NM_001040138.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chemokine like factor (CKLF), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040138.2

ORF Insert Sequence:

ATGGATAACG TGCAGCCGAA AATAAAACAT CGCCCCTTCT GCTTCAGTGT GAAAGGCCAC 
GTGAAGATGC TGCGGCTGGC ACTAACTGTG ACATCTATGA CCTTTTTTAT CATCGCACAA 
GCCCCTGAAC CATATATTGT TATCACTGGA TTTGAAGTCA CCGTTATCTT ATTTTTCATA 
CTTTTATATG TACTCAGACT TGATCGATTA ATGAAGTGGT TATTTTGGCC TTTGCTTGAT 
ATTATCAACT CACTGGTAAC AACAGTATTC ATGCTCATCG TATCTGTGTT GGCACTGATA 
CCAGAAACCA CAACATTGAC AGTTGGTGGA GGGTTATTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer.
Oncotarget7(24)36632-36644(2016 Jun)
Dunne PD,O'Reilly PG,Coleman HG,Gray RT,Longley DB,Johnston PG,Salto-Tellez M,Lawler M,McArt DG

Chemokine-Like Factor 1 (CKLF-1) is Overexpressed in Keloid Patients: A Potential Indicating Factor for Keloid-Predisposed Individuals.
Medicine95(11)e3082(2016 Mar)
Zhang M,Xu Y,Liu Y,Cheng Y,Zhao P,Liu H,Wang Y,Ma X

Distinct expression of chemokine-like factor 1 in synovium of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban36(1)70-6(2016 Feb)
Tao K,Tang X,Wang B,Li RJ,Zhang BQ,Lin JH,Li H

Chemokine-like factor 1-derived C-terminal peptides induce the proliferation of dermal microvascular endothelial cells in psoriasis.
PloS one10(4)e0125073(2015)
Tan Y,Wang Y,Li L,Xia J,Peng S,He Y

Chemokine-like factor 1 (CLFK1) is over-expressed in patients with atopic dermatitis.
International journal of biological sciences9(8)759-65(2013)
Yang GY,Chen X,Sun YC,Ma CL,Qian G

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CKLF cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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