HSD17B11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HSD17B11
Entrez Gene ID	51170
Full Name	hydroxysteroid 17-beta dehydrogenase 11
Synonyms	17-BETA-HSD11,17-BETA-HSDXI,17BHSD11,DHRS8,PAN1B,RETSDR2,SDR16C2
General protein information	Preferred Names hydroxysteroid 17-beta dehydrogenase 11 Names estradiol 17-beta-dehydrogenase 11 17-beta-hydroxysteroid dehydrogenase type XI CTCL tumor antigen HD-CL-03 CTCL-associated antigen HD-CL-03 cutaneous T-cell lymphoma-associated antigen HD-CL-03 dehydrogenase/reductase SDR family member 8 retinal short-chain dehydrogenase/reductase 2 short chain dehydrogenase/reductase family 16C member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q22.1
Summary	Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009].
Disorder MIM:	612831

mRNA and Protein(s)

mRNA	Protein	Name
NM_016245.4	NP_057329.3	estradiol 17-beta-dehydrogenase 11 precursor
NM_016245.5	NP_057329.3	estradiol 17-beta-dehydrogenase 11 precursor
XM_011532021.1	XP_011530323.1	estradiol 17-beta-dehydrogenase 11 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	HSD17B11	NP_057329.2
Pan troglodytes (chimpanzee)	HSD17B11	XP_003310475.1
Bos taurus (cattle)	HSD17B11	NP_001039751.1
Rattus norvegicus (Norway rat)	Hsd17b11	NP_001004209.1
Gallus gallus (chicken)	HSD17B11	XP_420547.1
Xenopus tropicalis (tropical clawed frog)	hsd17b11	NP_001011304.1
Canis lupus familiaris (dog)	HSD17B11	XP_544970.3
Mus musculus (house mouse)	Hsd17b11	NP_444492.1
	HSD17B11	XP_001096902.1
Gallus gallus (chicken)	LOC428754	XP_426310.2

Gene Ontology
Bibliography

Related articles in PubMed

Human dehydrogenase/reductase (SDR family) member 8 (DHRS8): a description and evaluation of its biochemical properties.
Lundov? T, ?tambergov? H, Zemanov? L, Svobodov? M, Havr?nkov? J, ?afr M, Ws?l V
Molecular and cellular biochemistry411(1-2)35-42(2016 Jan)

Genetic variants associated with disordered eating.
Wade TD, Gordon S, Medland S, Bulik CM, Heath AC, Montgomery GW, Martin NG
The International journal of eating disorders46(6)594-608(2013 Sep)

Transcriptional regulation of type 11 17?-hydroxysteroid dehydrogenase expression in prostate cancer cells.
Rotinen M, Villar J, Celay J, Serrano I, Notario V, Enc?o I
Molecular and cellular endocrinology339(1-2)45-53(2011 Jun)

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.
Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, J?rnvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U
Chemico-biological interactions178(1-3)94-8(2009 Mar)

17beta-hydroxysteroid dehydrogenase type 11 (Pan1b) expression in human prostate cancer.
Nakamura Y, Suzuki T, Arai Y, Sasano H
Neoplasma56(4)317-20(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

knowledge of its in vitro activity together with a newly described expression pattern at the protein level in tissues involved in steroidogenesis and detoxification could suggest a potential role of DHRS8 in vivo
Title: Human dehydrogenase/reductase (SDR family) member 8 (DHRS8): a description and evaluation of its biochemical properties.

hydroxysteroid (17-beta) dehydrogenase 11 transcription in prostate cancer cells is regulated by Sp1 transcription factor and C-EBP alpha
Title: Transcriptional regulation of type 11 17?-hydroxysteroid dehydrogenase expression in prostate cancer cells.

Increased Pan1b is associated with prostate cancer of seminal vesicle invasion.
Title: 17beta-hydroxysteroid dehydrogenase type 11 (Pan1b) expression in human prostate cancer.

Mutation analyses suggest that the PAT-like motif in 17betaHSD11 will not be functionally similar to the canonical PAT motif.
Title: Identification and characterization of the ER/lipid droplet-targeting sequence in 17beta-hydroxysteroid dehydrogenase type 11.

Role for 17-beta-HSDXI in androgen metabolism during steroidogenesis.
Title: 17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells.

The following HSD17B11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSD17B11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16124	NM_016245.5 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu67733	XM_011532021.1 Latest version!	Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu16124	NM_016245.4	Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HSD17B11 ( NM_016245.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057329.3 Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), mRNA.

Price & Availability↑

CloneID	OHu16124
Clone ID Related Accession (Same CDS sequence)	NM_016245.4 , NM_016245.5
Accession Version	NM_016245.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	estradiol 17-beta-dehydrogenase 11 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU838518.1, BC014327.1, AF273056.1 and BM976691.1. On Apr 18, 2014 this sequence version replaced NM_016245.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.171899.1, SRR1660803.62005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2152474 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAATTTC TTCTGGACAT CCTCCTGCTT CTCCCGTTAC TGATCGTCTG CTCCCTAGAG 
TCCTTCGTGA AGCTTTTTAT TCCTAAGAGG AGAAAATCAG TCACCGGCGA AATCGTGCTG 
ATTACAGGAG CTGGGCATGG AATTGGGAGA CTGACTGCCT ATGAATTTGC TAAACTTAAA 
AGCAAGCTGG TTCTCTGGGA TATAAATAAG CATGGACTGG AGGAAACAGC TGCCAAATGC 
AAGGGACTGG GTGCCAAGGT TCATACCTTT GTGGTAGACT GCAGCAACCG AGAAGATATT 
TACAGCTCTG CAAAGAAGGT GAAGGCAGAA ATTGGAGATG TTAGTATTTT AGTAAATAAT 
GCTGGTGTAG TCTATACATC AGATTTGTTT GCTACACAAG ATCCTCAGAT TGAAAAGACT 
TTTGAAGTTA ATGTACTTGC ACATTTCTGG ACTACAAAGG CATTTCTTCC TGCAATGACG 
AAGAATAACC ATGGCCATAT TGTCACTGTG GCTTCGGCAG CTGGACATGT CTCGGTCCCC 
TTCTTACTGG CTTACTGTTC AAGCAAGTTT GCTGCTGTTG GATTTCATAA AACTTTGACA 
GATGAACTGG CTGCCTTACA AATAACTGGA GTCAAAACAA CATGTCTGTG TCCTAATTTC 
GTAAACACTG GCTTCATCAA AAATCCAAGT ACAAGTTTGG GACCCACTCT GGAACCTGAG 
GAAGTGGTAA ACAGGCTGAT GCATGGGATT CTGACTGAGC AGAAGATGAT TTTTATTCCA 
TCTTCTATAG CTTTTTTAAC AACATTGGAA AGGATCCTTC CTGAGCGTTT CCTGGCAGTT 
TTAAAACGAA AAATCAGTGT TAAGTTTGAT GCAGTTATTG GATATAAAAT GAAAGCGCAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057329.3
CDS	234..1136
Translation	MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ

Target ORF information:

RefSeq Version	NM_016245.4
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016245.4

ORF Insert Sequence:

ATGAAATTTC TTCTGGACAT CCTCCTGCTT CTCCCGTTAC TGATCGTCTG CTCCCTAGAG 
TCCTTCGTGA AGCTTTTTAT TCCTAAGAGG AGAAAATCAG TCACCGGCGA AATCGTGCTG 
ATTACAGGAG CTGGGCATGG AATTGGGAGA CTGACTGCCT ATGAATTTGC TAAACTTAAA 
AGCAAGCTGG TTCTCTGGGA TATAAATAAG CATGGACTGG AGGAAACAGC TGCCAAATGC 
AAGGGACTGG GTGCCAAGGT TCATACCTTT GTGGTAGACT GCAGCAACCG AGAAGATATT 
TACAGCTCTG CAAAGAAGGT GAAGGCAGAA ATTGGAGATG TTAGTATTTT AGTAAATAAT 
GCTGGTGTAG TCTATACATC AGATTTGTTT GCTACACAAG ATCCTCAGAT TGAAAAGACT 
TTTGAAGTTA ATGTACTTGC ACATTTCTGG ACTACAAAGG CATTTCTTCC TGCAATGACG 
AAGAATAACC ATGGCCATAT TGTCACTGTG GCTTCGGCAG CTGGACATGT CTCGGTCCCC 
TTCTTACTGG CTTACTGTTC AAGCAAGTTT GCTGCTGTTG GATTTCATAA AACTTTGACA 
GATGAACTGG CTGCCTTACA AATAACTGGA GTCAAAACAA CATGTCTGTG TCCTAATTTC 
GTAAACACTG GCTTCATCAA AAATCCAAGT ACAAGTTTGG GACCCACTCT GGAACCTGAG 
GAAGTGGTAA ACAGGCTGAT GCATGGGATT CTGACTGAGC AGAAGATGAT TTTTATTCCA 
TCTTCTATAG CTTTTTTAAC AACATTGGAA AGGATCCTTC CTGAGCGTTT CCTGGCAGTT 
TTAAAACGAA AAATCAGTGT TAAGTTTGAT GCAGTTATTG GATATAAAAT GAAAGCGCAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B11 ( NM_016245.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057329.3 Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), mRNA.

Price & Availability↑

CloneID	OHu16124
Clone ID Related Accession (Same CDS sequence)	NM_016245.4 , NM_016245.5
Accession Version	NM_016245.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	estradiol 17-beta-dehydrogenase 11 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU838518.1, BC014327.1, AF273056.1, BM976691.1 and AC108516.5. On Nov 22, 2018 this sequence version replaced NM_016245.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK075348.1, SRR1803617.171899.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2152474 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000358290.9/ ENSP00000351035.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAATTTC TTCTGGACAT CCTCCTGCTT CTCCCGTTAC TGATCGTCTG CTCCCTAGAG 
TCCTTCGTGA AGCTTTTTAT TCCTAAGAGG AGAAAATCAG TCACCGGCGA AATCGTGCTG 
ATTACAGGAG CTGGGCATGG AATTGGGAGA CTGACTGCCT ATGAATTTGC TAAACTTAAA 
AGCAAGCTGG TTCTCTGGGA TATAAATAAG CATGGACTGG AGGAAACAGC TGCCAAATGC 
AAGGGACTGG GTGCCAAGGT TCATACCTTT GTGGTAGACT GCAGCAACCG AGAAGATATT 
TACAGCTCTG CAAAGAAGGT GAAGGCAGAA ATTGGAGATG TTAGTATTTT AGTAAATAAT 
GCTGGTGTAG TCTATACATC AGATTTGTTT GCTACACAAG ATCCTCAGAT TGAAAAGACT 
TTTGAAGTTA ATGTACTTGC ACATTTCTGG ACTACAAAGG CATTTCTTCC TGCAATGACG 
AAGAATAACC ATGGCCATAT TGTCACTGTG GCTTCGGCAG CTGGACATGT CTCGGTCCCC 
TTCTTACTGG CTTACTGTTC AAGCAAGTTT GCTGCTGTTG GATTTCATAA AACTTTGACA 
GATGAACTGG CTGCCTTACA AATAACTGGA GTCAAAACAA CATGTCTGTG TCCTAATTTC 
GTAAACACTG GCTTCATCAA AAATCCAAGT ACAAGTTTGG GACCCACTCT GGAACCTGAG 
GAAGTGGTAA ACAGGCTGAT GCATGGGATT CTGACTGAGC AGAAGATGAT TTTTATTCCA 
TCTTCTATAG CTTTTTTAAC AACATTGGAA AGGATCCTTC CTGAGCGTTT CCTGGCAGTT 
TTAAAACGAA AAATCAGTGT TAAGTTTGAT GCAGTTATTG GATATAAAAT GAAAGCGCAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057329.3
CDS	119..1021
Translation	MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ

Target ORF information:

RefSeq Version	NM_016245.5
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016245.5

ORF Insert Sequence:

ATGAAATTTC TTCTGGACAT CCTCCTGCTT CTCCCGTTAC TGATCGTCTG CTCCCTAGAG 
TCCTTCGTGA AGCTTTTTAT TCCTAAGAGG AGAAAATCAG TCACCGGCGA AATCGTGCTG 
ATTACAGGAG CTGGGCATGG AATTGGGAGA CTGACTGCCT ATGAATTTGC TAAACTTAAA 
AGCAAGCTGG TTCTCTGGGA TATAAATAAG CATGGACTGG AGGAAACAGC TGCCAAATGC 
AAGGGACTGG GTGCCAAGGT TCATACCTTT GTGGTAGACT GCAGCAACCG AGAAGATATT 
TACAGCTCTG CAAAGAAGGT GAAGGCAGAA ATTGGAGATG TTAGTATTTT AGTAAATAAT 
GCTGGTGTAG TCTATACATC AGATTTGTTT GCTACACAAG ATCCTCAGAT TGAAAAGACT 
TTTGAAGTTA ATGTACTTGC ACATTTCTGG ACTACAAAGG CATTTCTTCC TGCAATGACG 
AAGAATAACC ATGGCCATAT TGTCACTGTG GCTTCGGCAG CTGGACATGT CTCGGTCCCC 
TTCTTACTGG CTTACTGTTC AAGCAAGTTT GCTGCTGTTG GATTTCATAA AACTTTGACA 
GATGAACTGG CTGCCTTACA AATAACTGGA GTCAAAACAA CATGTCTGTG TCCTAATTTC 
GTAAACACTG GCTTCATCAA AAATCCAAGT ACAAGTTTGG GACCCACTCT GGAACCTGAG 
GAAGTGGTAA ACAGGCTGAT GCATGGGATT CTGACTGAGC AGAAGATGAT TTTTATTCCA 
TCTTCTATAG CTTTTTTAAC AACATTGGAA AGGATCCTTC CTGAGCGTTT CCTGGCAGTT 
TTAAAACGAA AAATCAGTGT TAAGTTTGAT GCAGTTATTG GATATAAAAT GAAAGCGCAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HSD17B11 ( XM_011532021.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530323.1 Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu67733
Clone ID Related Accession (Same CDS sequence)	XM_011532021.1
Accession Version	XM_011532021.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	estradiol 17-beta-dehydrogenase 11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAATTTC TTCTGGACAT CCTCCTGCTT CTCCCGTTAC TGATCGTCTG CTCCCTAGAG 
TCCTTCGTGA AGCTTTTTAT TCCTAAGAGG AGAAAATCAG TCACCGGCGA AATCGTGCTG 
ATTACAGGAG CTGGGCATGG AATTGGGAGA CTGACTGCCT ATGAATTTGC TAAACTTAAA 
AGCAAGCTGG TTCTCTGGGA TATAAATAAG CATGGACTGG AGGAAACAGC TGCCAAATGC 
AAGGGACTGG GTGCCAAGGT TCATACCTTT GTGGTAGACT GCAGCAACCG AGAAGATATT 
TACAGCTCTG CAAAGAAGGT GAAGGCAGAA ATTGGAGATG TTAGTATTTT AGTAAATAAT 
GCTGGTGTAG TCTATACATC AGATTTGTTT GCTACACAAG ATCCTCAGAT TGAAAAGACT 
TTTGAAGTTA ATGTACTTGC ACATTTCTGG AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530323.1
CDS	183..638
Translation	MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWR

Target ORF information:

RefSeq Version	XM_011532021.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532021.1

ORF Insert Sequence:

ATGAAATTTC TTCTGGACAT CCTCCTGCTT CTCCCGTTAC TGATCGTCTG CTCCCTAGAG 
TCCTTCGTGA AGCTTTTTAT TCCTAAGAGG AGAAAATCAG TCACCGGCGA AATCGTGCTG 
ATTACAGGAG CTGGGCATGG AATTGGGAGA CTGACTGCCT ATGAATTTGC TAAACTTAAA 
AGCAAGCTGG TTCTCTGGGA TATAAATAAG CATGGACTGG AGGAAACAGC TGCCAAATGC 
AAGGGACTGG GTGCCAAGGT TCATACCTTT GTGGTAGACT GCAGCAACCG AGAAGATATT 
TACAGCTCTG CAAAGAAGGT GAAGGCAGAA ATTGGAGATG TTAGTATTTT AGTAAATAAT 
GCTGGTGTAG TCTATACATC AGATTTGTTT GCTACACAAG ATCCTCAGAT TGAAAAGACT 
TTTGAAGTTA ATGTACTTGC ACATTTCTGG AGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human dehydrogenase/reductase (SDR family) member 8 (DHRS8): a description and evaluation of its biochemical properties.
Molecular and cellular biochemistry411(1-2)35-42(2016 Jan)
Lundov? T,?tambergov? H,Zemanov? L,Svobodov? M,Havr?nkov? J,?afr M,Ws?l V

Genetic variants associated with disordered eating.
The International journal of eating disorders46(6)594-608(2013 Sep)
Wade TD,Gordon S,Medland S,Bulik CM,Heath AC,Montgomery GW,Martin NG

Transcriptional regulation of type 11 17?-hydroxysteroid dehydrogenase expression in prostate cancer cells.
Molecular and cellular endocrinology339(1-2)45-53(2011 Jun)
Rotinen M,Villar J,Celay J,Serrano I,Notario V,Enc?o I

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.
Chemico-biological interactions178(1-3)94-8(2009 Mar)
Persson B,Kallberg Y,Bray JE,Bruford E,Dellaporta SL,Favia AD,Duarte RG,J?rnvall H,Kavanagh KL,Kedishvili N,Kisiela M,Maser E,Mindnich R,Orchard S,Penning TM,Thornton JM,Adamski J,Oppermann U

17beta-hydroxysteroid dehydrogenase type 11 (Pan1b) expression in human prostate cancer.
Neoplasma56(4)317-20(2009)
Nakamura Y,Suzuki T,Arai Y,Sasano H

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HSD17B11 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

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電話

FAX

オンラインフォーム