AADAT cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AADAT
Entrez Gene ID	51166
Full Name	aminoadipate aminotransferase
Synonyms	KAT2,KATII,KYAT2
General protein information	Preferred Names aminoadipate aminotransferase Names kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 2-aminoadipate aminotransferase 2-aminoadipate transaminase KAT/AadAT L kynurenine/alpha aminoadipate aminotransferase alpha-aminoadipate aminotransferase kynurenine aminotransferase II kynurenine--oxoglutarate aminotransferase II kynurenine--oxoglutarate transaminase 2 kynurenine--oxoglutarate transaminase II
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q33
Summary	This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013].
Disorder MIM:	611754

mRNA and Protein(s)

mRNA	Protein	Name
XM_024454077.1	XP_024309845.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X2
NM_001286682.1	NP_001273611.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform a
NM_016228.4	NP_057312.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
NM_182662.1	NP_872603.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
NM_001286683.1	NP_001273612.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
XM_006714231.2	XP_006714294.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1
NM_016228.3	NP_057312.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
XM_011532020.2	XP_011530322.1	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X3

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Aadat	NP_058889.1
Danio rerio (zebrafish)	LOC557979	XP_686234.6
Xenopus tropicalis (tropical clawed frog)	aadat	NP_001011226.1
Pan troglodytes (chimpanzee)	AADAT	XP_001155018.1
Canis lupus familiaris (dog)	AADAT	XP_543185.4
Magnaporthe oryzae (rice blast fungus)	MGG_14221	XP_003720489.1
Homo sapiens (human)	AADAT	NP_872603.1
Bos taurus (cattle)	LOC520638	XP_002689494.1
	AADAT	XP_002804303.1
Mus musculus (house mouse)	Aadat	NP_035964.1
Bos taurus (cattle)	AADAT	NP_001015551.1
Gallus gallus (chicken)	AADAT	XP_426286.3

Gene Ontology
Bibliography

Related articles in PubMed

The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.
Matysik-Wo?niak A, J?nemann A, Turski WA, Wnorowski A, J??wiak K, Paduch R, Okuno E, Moneta-Wielgo? J, Chor?giewicz T, Maciejewski R, Rejdak R
Molecular vision23364-371(2017)

Expression, purification and crystallization of human kynurenine aminotransferase 2 exploiting a highly optimized codon set.
Sun G, Nematollahi A, Nadvi NA, Kwan AH, Jeffries CM, Church WB
Protein expression and purification12141-5(2016 May)

Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA.
Hennings A, Schwarz MJ, Riemer S, Stapf TM, Selberdinger VB, Rief W
Psychiatry research210(3)925-33(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

he optimised method of protein production provides a fast and reliable technique to generate large quantities of active human KAT2 suitable for future small-molecule lead compound screening and structural design work.
Title: Expression, purification and crystallization of human kynurenine aminotransferase 2 exploiting a highly optimized codon set.

Participants with major depression had lower levels of kynurenine compared to controls, with intermediate concentrations in somatoform patients.
Title: Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA.

association of SNP AADAT+401C/T with the host immune response to bacterial meningitis, suggesting that this SNP may affect the host ability in recruitment of leukocytes to the infection site
Title: Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis.

Somatization is characterized by disorders in kynurenine aminotransferase activity and an increased neurotoxic potential
Title: Somatization, but not depression, is characterized by disorders in the tryptophan catabolite (TRYCAT) pathway, indicating increased indoleamine 2,3-dioxygenase and lowered kynurenine aminotransferase activity.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following AADAT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AADAT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09877	NM_182662.1 Latest version!	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu09877	NM_016228.4 Latest version!	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu09877	NM_001286683.1 Latest version!	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu22198	NM_001286682.1 Latest version!	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu09877	XM_024454077.1 Latest version!	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu38957	XM_006714231.2 Latest version!	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu67727	XM_011532020.2 Latest version!	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu09877	NM_016228.3	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AADAT ( NM_016228.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057312.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09877
Clone ID Related Accession (Same CDS sequence)	XM_024454077.1 , NM_016228.4 , NM_182662.1 , NM_001286683.1 , NM_016228.3
Accession Version	NM_016228.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC084866.5. On Nov 26, 2018 this sequence version replaced NM_016228.3. Transcript Variant: This variant (1) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of the first coding exon compared to variant 3. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 2, and 4 all encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF481738.1, SRR1660807.13797.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000337664.9/ ENSP00000336808.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057312.1
CDS	267..1544
Translation	MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	NM_016228.4
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016228.4

ORF Insert Sequence:

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AADAT ( NM_182662.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_872603.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09877
Clone ID Related Accession (Same CDS sequence)	XM_024454077.1 , NM_016228.4 , NM_182662.1 , NM_001286683.1 , NM_016228.3
Accession Version	NM_182662.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-23
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055952.1. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 3' end of the first coding exon compared to variant 3. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 2, and 4 all encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK055952.1, SRR1660809.197907.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872603.1
CDS	125..1402
Translation	MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	NM_182662.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182662.1

ORF Insert Sequence:

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AADAT ( NM_001286683.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273612.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu09877
Clone ID Related Accession (Same CDS sequence)	XM_024454077.1 , NM_016228.4 , NM_182662.1 , NM_001286683.1 , NM_016228.3
Accession Version	NM_001286683.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314729.1 and BC031068.1. Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of the first coding exon compared to variant 3. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 2, and 4 all encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314729.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273612.1
CDS	210..1487
Translation	MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	NM_001286683.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286683.1

ORF Insert Sequence:

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AADAT ( NM_016228.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057312.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 1, mRNA.

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CloneID	OHu09877
Clone ID Related Accession (Same CDS sequence)	XM_024454077.1 , NM_016228.4 , NM_182662.1 , NM_001286683.1 , NM_016228.3
Accession Version	NM_016228.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF097994.1. On Aug 7, 2003 this sequence version replaced NM_016228.2. Transcript Variant: This variant (1) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of the first coding exon compared to variant 3. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 2, and 4 all encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF481738.1, SRR1660807.13797.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057312.1
CDS	343..1620
Translation	MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	NM_016228.3
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016228.3

ORF Insert Sequence:

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AADAT ( NM_001286682.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273611.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 3, mRNA.

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CloneID	OHu22198
Clone ID Related Accession (Same CDS sequence)	NM_001286682.1
Accession Version	NM_001286682.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1290bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055952.1, BC031068.1 and AK314729.1. Transcript Variant: This variant (3) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031068.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGAGTG AGAAACGGGC TGACATATTG AGCAGAGGAC CAAAATCGAT GATCTCCTTG 
GCTGGTGGCT TACCAAATCC AAACATGTTT CCTTTTAAGA CTGCCGTAAT CACTGTAGAA 
AATGGAAAGA CCATCCAATT TGGAGAAGAG ATGATGAAGA GAGCACTTCA GTATTCTCCG 
AGTGCTGGAA TTCCAGAGCT TTTGTCCTGG CTAAAACAGT TACAAATAAA ATTGCATAAT 
CCTCCTACCA TCCATTACCC ACCCAGTCAA GGACAAATGG ATCTATGTGT CACATCTGGC 
AGCCAACAAG GTCTTTGTAA GGTGTTTGAA ATGATCATTA ATCCTGGAGA TAATGTCCTC 
CTAGATGAAC CTGCTTATTC AGGAACTCTT CAAAGTCTGC ACCCACTGGG CTGCAACATT 
ATTAATGTTG CCAGTGATGA AAGTGGGATT GTTCCAGATT CCCTAAGAGA CATACTTTCC 
AGATGGAAAC CAGAAGATGC AAAGAATCCC CAGAAAAACA CCCCCAAATT TCTTTATACT 
GTTCCAAATG GCAACAACCC TACTGGAAAC TCATTAACCA GTGAACGCAA AAAGGAAATC 
TATGAGCTTG CAAGAAAATA TGATTTCCTC ATAATAGAAG ATGATCCTTA CTATTTTCTC 
CAGTTTAACA AGTTCAGGGT ACCAACATTT CTTTCCATGG ATGTTGATGG ACGTGTCATC 
AGAGCTGACT CTTTTTCAAA AATCATTTCC TCTGGGTTGA GAATAGGATT TTTAACTGGT 
CCAAAACCCT TAATAGAGAG AGTTATTTTA CACATACAAG TTTCAACATT GCACCCCAGC 
ACTTTTAACC AGCTCATGAT ATCACAGCTT CTACACGAAT GGGGAGAAGA AGGTTTCATG 
GCTCATGTAG ACAGGGTTAT TGATTTCTAT AGTAACCAGA AGGATGCAAT ACTGGCAGCT 
GCAGACAAGT GGTTAACTGG TTTGGCAGAA TGGCATGTTC CTGCTGCTGG AATGTTTTTA 
TGGATTAAAG TTAAAGGCAT TAATGATGTA AAAGAACTGA TTGAAGAAAA GGCCGTTAAG 
ATGGGGGTAT TAATGCTCCC TGGAAATGCT TTCTACGTCG ATAGCTCAGC TCCTAGCCCT 
TACTTGAGAG CATCCTTCTC TTCAGCTTCT CCAGAACAGA TGGATGTGGC CTTCCAGGTA 
TTAGCACAAC TTATAAAAGA ATCTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273611.1
CDS	125..1414
Translation	MNYARFITAASAARNPSPIRTMSEKRADILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	NM_001286682.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286682.1

ORF Insert Sequence:

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGAGTG AGAAACGGGC TGACATATTG AGCAGAGGAC CAAAATCGAT GATCTCCTTG 
GCTGGTGGCT TACCAAATCC AAACATGTTT CCTTTTAAGA CTGCCGTAAT CACTGTAGAA 
AATGGAAAGA CCATCCAATT TGGAGAAGAG ATGATGAAGA GAGCACTTCA GTATTCTCCG 
AGTGCTGGAA TTCCAGAGCT TTTGTCCTGG CTAAAACAGT TACAAATAAA ATTGCATAAT 
CCTCCTACCA TCCATTACCC ACCCAGTCAA GGACAAATGG ATCTATGTGT CACATCTGGC 
AGCCAACAAG GTCTTTGTAA GGTGTTTGAA ATGATCATTA ATCCTGGAGA TAATGTCCTC 
CTAGATGAAC CTGCTTATTC AGGAACTCTT CAAAGTCTGC ACCCACTGGG CTGCAACATT 
ATTAATGTTG CCAGTGATGA AAGTGGGATT GTTCCAGATT CCCTAAGAGA CATACTTTCC 
AGATGGAAAC CAGAAGATGC AAAGAATCCC CAGAAAAACA CCCCCAAATT TCTTTATACT 
GTTCCAAATG GCAACAACCC TACTGGAAAC TCATTAACCA GTGAACGCAA AAAGGAAATC 
TATGAGCTTG CAAGAAAATA TGATTTCCTC ATAATAGAAG ATGATCCTTA CTATTTTCTC 
CAGTTTAACA AGTTCAGGGT ACCAACATTT CTTTCCATGG ATGTTGATGG ACGTGTCATC 
AGAGCTGACT CTTTTTCAAA AATCATTTCC TCTGGGTTGA GAATAGGATT TTTAACTGGT 
CCAAAACCCT TAATAGAGAG AGTTATTTTA CACATACAAG TTTCAACATT GCACCCCAGC 
ACTTTTAACC AGCTCATGAT ATCACAGCTT CTACACGAAT GGGGAGAAGA AGGTTTCATG 
GCTCATGTAG ACAGGGTTAT TGATTTCTAT AGTAACCAGA AGGATGCAAT ACTGGCAGCT 
GCAGACAAGT GGTTAACTGG TTTGGCAGAA TGGCATGTTC CTGCTGCTGG AATGTTTTTA 
TGGATTAAAG TTAAAGGCAT TAATGATGTA AAAGAACTGA TTGAAGAAAA GGCCGTTAAG 
ATGGGGGTAT TAATGCTCCC TGGAAATGCT TTCTACGTCG ATAGCTCAGC TCCTAGCCCT 
TACTTGAGAG CATCCTTCTC TTCAGCTTCT CCAGAACAGA TGGATGTGGC CTTCCAGGTA 
TTAGCACAAC TTATAAAAGA ATCTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AADAT ( XM_024454077.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309845.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu09877
Clone ID Related Accession (Same CDS sequence)	XM_024454077.1 , NM_016228.4 , NM_182662.1 , NM_001286683.1 , NM_016228.3
Accession Version	XM_024454077.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309845.1
CDS	177..1454
Translation	MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	XM_024454077.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024454077.1

ORF Insert Sequence:

ATGAATTACG CACGGTTCAT CACGGCAGCG AGCGCAGCCA GAAACCCTTC TCCCATCCGG 
ACCATGACTG ACATATTGAG CAGAGGACCA AAATCGATGA TCTCCTTGGC TGGTGGCTTA 
CCAAATCCAA ACATGTTTCC TTTTAAGACT GCCGTAATCA CTGTAGAAAA TGGAAAGACC 
ATCCAATTTG GAGAAGAGAT GATGAAGAGA GCACTTCAGT ATTCTCCGAG TGCTGGAATT 
CCAGAGCTTT TGTCCTGGCT AAAACAGTTA CAAATAAAAT TGCATAATCC TCCTACCATC 
CATTACCCAC CCAGTCAAGG ACAAATGGAT CTATGTGTCA CATCTGGCAG CCAACAAGGT 
CTTTGTAAGG TGTTTGAAAT GATCATTAAT CCTGGAGATA ATGTCCTCCT AGATGAACCT 
GCTTATTCAG GAACTCTTCA AAGTCTGCAC CCACTGGGCT GCAACATTAT TAATGTTGCC 
AGTGATGAAA GTGGGATTGT TCCAGATTCC CTAAGAGACA TACTTTCCAG ATGGAAACCA 
GAAGATGCAA AGAATCCCCA GAAAAACACC CCCAAATTTC TTTATACTGT TCCAAATGGC 
AACAACCCTA CTGGAAACTC ATTAACCAGT GAACGCAAAA AGGAAATCTA TGAGCTTGCA 
AGAAAATATG ATTTCCTCAT AATAGAAGAT GATCCTTACT ATTTTCTCCA GTTTAACAAG 
TTCAGGGTAC CAACATTTCT TTCCATGGAT GTTGATGGAC GTGTCATCAG AGCTGACTCT 
TTTTCAAAAA TCATTTCCTC TGGGTTGAGA ATAGGATTTT TAACTGGTCC AAAACCCTTA 
ATAGAGAGAG TTATTTTACA CATACAAGTT TCAACATTGC ACCCCAGCAC TTTTAACCAG 
CTCATGATAT CACAGCTTCT ACACGAATGG GGAGAAGAAG GTTTCATGGC TCATGTAGAC 
AGGGTTATTG ATTTCTATAG TAACCAGAAG GATGCAATAC TGGCAGCTGC AGACAAGTGG 
TTAACTGGTT TGGCAGAATG GCATGTTCCT GCTGCTGGAA TGTTTTTATG GATTAAAGTT 
AAAGGCATTA ATGATGTAAA AGAACTGATT GAAGAAAAGG CCGTTAAGAT GGGGGTATTA 
ATGCTCCCTG GAAATGCTTT CTACGTCGAT AGCTCAGCTC CTAGCCCTTA CTTGAGAGCA 
TCCTTCTCTT CAGCTTCTCC AGAACAGATG GATGTGGCCT TCCAGGTATT AGCACAACTT 
ATAAAAGAAT CTTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AADAT ( XM_006714231.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006714294.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X1, mRNA.

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CloneID	OHu38957
Clone ID Related Accession (Same CDS sequence)	XM_006714231.2
Accession Version	XM_006714231.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006714231.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGAAAT TCGTCTTGGT CGCCGGGATG CTTCCCAGGA GAGTGCCCAG AGTTTCACTA 
ACGAAAGATG GTCCTCAACC ACTGAAGAAG AAGCTTGATG CTTGGCTGTC AGAAGACATG 
AATTACGCAC GGTTCATCAC GGCAGCGAGC GCAGCCAGAA ACCCTTCTCC CATCCGGACC 
ATGACTGACA TATTGAGCAG AGGACCAAAA TCGATGATCT CCTTGGCTGG TGGCTTACCA 
AATCCAAACA TGTTTCCTTT TAAGACTGCC GTAATCACTG TAGAAAATGG AAAGACCATC 
CAATTTGGAG AAGAGATGAT GAAGAGAGCA CTTCAGTATT CTCCGAGTGC TGGAATTCCA 
GAGCTTTTGT CCTGGCTAAA ACAGTTACAA ATAAAATTGC ATAATCCTCC TACCATCCAT 
TACCCACCCA GTCAAGGACA AATGGATCTA TGTGTCACAT CTGGCAGCCA ACAAGGTCTT 
TGTAAGGTGT TTGAAATGAT CATTAATCCT GGAGATAATG TCCTCCTAGA TGAACCTGCT 
TATTCAGGAA CTCTTCAAAG TCTGCACCCA CTGGGCTGCA ACATTATTAA TGTTGCCAGT 
GATGAAAGTG GGATTGTTCC AGATTCCCTA AGAGACATAC TTTCCAGATG GAAACCAGAA 
GATGCAAAGA ATCCCCAGAA AAACACCCCC AAATTTCTTT ATACTGTTCC AAATGGCAAC 
AACCCTACTG GAAACTCATT AACCAGTGAA CGCAAAAAGG AAATCTATGA GCTTGCAAGA 
AAATATGATT TCCTCATAAT AGAAGATGAT CCTTACTATT TTCTCCAGTT TAACAAGTTC 
AGGGTACCAA CATTTCTTTC CATGGATGTT GATGGACGTG TCATCAGAGC TGACTCTTTT 
TCAAAAATCA TTTCCTCTGG GTTGAGAATA GGATTTTTAA CTGGTCCAAA ACCCTTAATA 
GAGAGAGTTA TTTTACACAT ACAAGTTTCA ACATTGCACC CCAGCACTTT TAACCAGCTC 
ATGATATCAC AGCTTCTACA CGAATGGGGA GAAGAAGGTT TCATGGCTCA TGTAGACAGG 
GTTATTGATT TCTATAGTAA CCAGAAGGAT GCAATACTGG CAGCTGCAGA CAAGTGGTTA 
ACTGGTTTGG CAGAATGGCA TGTTCCTGCT GCTGGAATGT TTTTATGGAT TAAAGTTAAA 
GGCATTAATG ATGTAAAAGA ACTGATTGAA GAAAAGGCCG TTAAGATGGG GGTATTAATG 
CTCCCTGGAA ATGCTTTCTA CGTCGATAGC TCAGCTCCTA GCCCTTACTT GAGAGCATCC 
TTCTCTTCAG CTTCTCCAGA ACAGATGGAT GTGGCCTTCC AGGTATTAGC ACAACTTATA 
AAAGAATCTT TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006714294.1
CDS	150..1544
Translation	MLKFVLVAGMLPRRVPRVSLTKDGPQPLKKKLDAWLSEDMNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	XM_006714231.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006714231.2

ORF Insert Sequence:

ATGTTGAAAT TCGTCTTGGT CGCCGGGATG CTTCCCAGGA GAGTGCCCAG AGTTTCACTA 
ACGAAAGATG GTCCTCAACC ACTGAAGAAG AAGCTTGATG CTTGGCTGTC AGAAGACATG 
AATTACGCAC GGTTCATCAC GGCAGCGAGC GCAGCCAGAA ACCCTTCTCC CATCCGGACC 
ATGACTGACA TATTGAGCAG AGGACCAAAA TCGATGATCT CCTTGGCTGG TGGCTTACCA 
AATCCAAACA TGTTTCCTTT TAAGACTGCC GTAATCACTG TAGAAAATGG AAAGACCATC 
CAATTTGGAG AAGAGATGAT GAAGAGAGCA CTTCAGTATT CTCCGAGTGC TGGAATTCCA 
GAGCTTTTGT CCTGGCTAAA ACAGTTACAA ATAAAATTGC ATAATCCTCC TACCATCCAT 
TACCCACCCA GTCAAGGACA AATGGATCTA TGTGTCACAT CTGGCAGCCA ACAAGGTCTT 
TGTAAGGTGT TTGAAATGAT CATTAATCCT GGAGATAATG TCCTCCTAGA TGAACCTGCT 
TATTCAGGAA CTCTTCAAAG TCTGCACCCA CTGGGCTGCA ACATTATTAA TGTTGCCAGT 
GATGAAAGTG GGATTGTTCC AGATTCCCTA AGAGACATAC TTTCCAGATG GAAACCAGAA 
GATGCAAAGA ATCCCCAGAA AAACACCCCC AAATTTCTTT ATACTGTTCC AAATGGCAAC 
AACCCTACTG GAAACTCATT AACCAGTGAA CGCAAAAAGG AAATCTATGA GCTTGCAAGA 
AAATATGATT TCCTCATAAT AGAAGATGAT CCTTACTATT TTCTCCAGTT TAACAAGTTC 
AGGGTACCAA CATTTCTTTC CATGGATGTT GATGGACGTG TCATCAGAGC TGACTCTTTT 
TCAAAAATCA TTTCCTCTGG GTTGAGAATA GGATTTTTAA CTGGTCCAAA ACCCTTAATA 
GAGAGAGTTA TTTTACACAT ACAAGTTTCA ACATTGCACC CCAGCACTTT TAACCAGCTC 
ATGATATCAC AGCTTCTACA CGAATGGGGA GAAGAAGGTT TCATGGCTCA TGTAGACAGG 
GTTATTGATT TCTATAGTAA CCAGAAGGAT GCAATACTGG CAGCTGCAGA CAAGTGGTTA 
ACTGGTTTGG CAGAATGGCA TGTTCCTGCT GCTGGAATGT TTTTATGGAT TAAAGTTAAA 
GGCATTAATG ATGTAAAAGA ACTGATTGAA GAAAAGGCCG TTAAGATGGG GGTATTAATG 
CTCCCTGGAA ATGCTTTCTA CGTCGATAGC TCAGCTCCTA GCCCTTACTT GAGAGCATCC 
TTCTCTTCAG CTTCTCCAGA ACAGATGGAT GTGGCCTTCC AGGTATTAGC ACAACTTATA 
AAAGAATCTT TATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AADAT ( XM_011532020.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530322.1 Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X3, mRNA.

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CloneID	OHu67727
Clone ID Related Accession (Same CDS sequence)	XM_011532020.2
Accession Version	XM_011532020.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 933bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	kynurenine/alpha-aminoadipate aminotransferase, mitochondrial isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532020.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAAAG CTCATAAGGA AAAGGTGTTT GAAATGATCA TTAATCCTGG AGATAATGTC 
CTCCTAGATG AACCTGCTTA TTCAGGAACT CTTCAAAGTC TGCACCCACT GGGCTGCAAC 
ATTATTAATG TTGCCAGTGA TGAAAGTGGG ATTGTTCCAG ATTCCCTAAG AGACATACTT 
TCCAGATGGA AACCAGAAGA TGCAAAGAAT CCCCAGAAAA ACACCCCCAA ATTTCTTTAT 
ACTGTTCCAA ATGGCAACAA CCCTACTGGA AACTCATTAA CCAGTGAACG CAAAAAGGAA 
ATCTATGAGC TTGCAAGAAA ATATGATTTC CTCATAATAG AAGATGATCC TTACTATTTT 
CTCCAGTTTA ACAAGTTCAG GGTACCAACA TTTCTTTCCA TGGATGTTGA TGGACGTGTC 
ATCAGAGCTG ACTCTTTTTC AAAAATCATT TCCTCTGGGT TGAGAATAGG ATTTTTAACT 
GGTCCAAAAC CCTTAATAGA GAGAGTTATT TTACACATAC AAGTTTCAAC ATTGCACCCC 
AGCACTTTTA ACCAGCTCAT GATATCACAG CTTCTACACG AATGGGGAGA AGAAGGTTTC 
ATGGCTCATG TAGACAGGGT TATTGATTTC TATAGTAACC AGAAGGATGC AATACTGGCA 
GCTGCAGACA AGTGGTTAAC TGGTTTGGCA GAATGGCATG TTCCTGCTGC TGGAATGTTT 
TTATGGATTA AAGTTAAAGG CATTAATGAT GTAAAAGAAC TGATTGAAGA AAAGGCCGTT 
AAGATGGGGG TATTAATGCT CCCTGGAAAT GCTTTCTACG TCGATAGCTC AGCTCCTAGC 
CCTTACTTGA GAGCATCCTT CTCTTCAGCT TCTCCAGAAC AGATGGATGT GGCCTTCCAG 
GTATTAGCAC AACTTATAAA AGAATCTTTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530322.1
CDS	245..1177
Translation	MPKAHKEKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNKFRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL

Target ORF information:

RefSeq Version	XM_011532020.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aminoadipate aminotransferase (AADAT), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532020.2

ORF Insert Sequence:

ATGCCAAAAG CTCATAAGGA AAAGGTGTTT GAAATGATCA TTAATCCTGG AGATAATGTC 
CTCCTAGATG AACCTGCTTA TTCAGGAACT CTTCAAAGTC TGCACCCACT GGGCTGCAAC 
ATTATTAATG TTGCCAGTGA TGAAAGTGGG ATTGTTCCAG ATTCCCTAAG AGACATACTT 
TCCAGATGGA AACCAGAAGA TGCAAAGAAT CCCCAGAAAA ACACCCCCAA ATTTCTTTAT 
ACTGTTCCAA ATGGCAACAA CCCTACTGGA AACTCATTAA CCAGTGAACG CAAAAAGGAA 
ATCTATGAGC TTGCAAGAAA ATATGATTTC CTCATAATAG AAGATGATCC TTACTATTTT 
CTCCAGTTTA ACAAGTTCAG GGTACCAACA TTTCTTTCCA TGGATGTTGA TGGACGTGTC 
ATCAGAGCTG ACTCTTTTTC AAAAATCATT TCCTCTGGGT TGAGAATAGG ATTTTTAACT 
GGTCCAAAAC CCTTAATAGA GAGAGTTATT TTACACATAC AAGTTTCAAC ATTGCACCCC 
AGCACTTTTA ACCAGCTCAT GATATCACAG CTTCTACACG AATGGGGAGA AGAAGGTTTC 
ATGGCTCATG TAGACAGGGT TATTGATTTC TATAGTAACC AGAAGGATGC AATACTGGCA 
GCTGCAGACA AGTGGTTAAC TGGTTTGGCA GAATGGCATG TTCCTGCTGC TGGAATGTTT 
TTATGGATTA AAGTTAAAGG CATTAATGAT GTAAAAGAAC TGATTGAAGA AAAGGCCGTT 
AAGATGGGGG TATTAATGCT CCCTGGAAAT GCTTTCTACG TCGATAGCTC AGCTCCTAGC 
CCTTACTTGA GAGCATCCTT CTCTTCAGCT TCTCCAGAAC AGATGGATGT GGCCTTCCAG 
GTATTAGCAC AACTTATAAA AGAATCTTTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.
Molecular vision23364-371(2017)
Matysik-Wo?niak A,J?nemann A,Turski WA,Wnorowski A,J??wiak K,Paduch R,Okuno E,Moneta-Wielgo? J,Chor?giewicz T,Maciejewski R,Rejdak R

Expression, purification and crystallization of human kynurenine aminotransferase 2 exploiting a highly optimized codon set.
Protein expression and purification12141-5(2016 May)
Sun G,Nematollahi A,Nadvi NA,Kwan AH,Jeffries CM,Church WB

Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA.
Psychiatry research210(3)925-33(2013 Dec)
Hennings A,Schwarz MJ,Riemer S,Stapf TM,Selberdinger VB,Rief W

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AADAT cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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