DCTN4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DCTN4
Entrez Gene ID	51164
Full Name	dynactin subunit 4
Synonyms	DYN4,P62
General protein information	Preferred Names dynactin subunit 4 Names dynactin subunit 4 dynactin 4 (p62) dynactin p62 subunit dynactin subunit p62
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q33.1
Disorder MIM:	614758

mRNA and Protein(s)

mRNA	Protein	Name
NM_001135643.1	NP_001129115.1	dynactin subunit 4 isoform a
NM_001135644.1	NP_001129116.1	dynactin subunit 4 isoform c
XM_011537647.1	XP_011535949.1	dynactin subunit 4 isoform X3
XM_011537646.1	XP_011535948.1	dynactin subunit 4 isoform X2
NM_016221.3	NP_057305.1	dynactin subunit 4 isoform b
XM_011537644.1	XP_011535946.1	dynactin subunit 4 isoform X1
XM_011537645.1	XP_011535947.1	dynactin subunit 4 isoform X1
XM_005268457.1	XP_005268514.1	dynactin subunit 4 isoform X3

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Dctn4	NP_445856.1
Gallus gallus (chicken)	DCTN4	XP_003642109.1
Drosophila melanogaster (fruit fly)	CG12042	NP_610311.1
Xenopus tropicalis (tropical clawed frog)	dctn4	NP_001025673.1
Mus musculus (house mouse)	Dctn4	NP_080578.1
Pan troglodytes (chimpanzee)	DCTN4	XP_001167091.1
Canis lupus familiaris (dog)	DCTN4	XP_867523.1
Bos taurus (cattle)	DCTN4	NP_001178460.1
	DCTN4	XP_001109230.1
Homo sapiens (human)	DCTN4	NP_057305.1
Danio rerio (zebrafish)	dctn4	NP_001017782.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000908	XP_316886.4
Caenorhabditis elegans (roundworm)	dnc-4	NP_501344.1

Gene Ontology
Bibliography

Related articles in PubMed

DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Viel M, Hubert D, Burgel PR, G?nin E, Honor? I, Martinez B, Gaitch N, Chapron J, Kanaan R, Dusser D, Girodon E, Bienvenu T
The clinical respiratory journal10(6)777-783(2016 Nov)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
Gupta GD, Coyaud ?, Gon?alves J, Mojarad BA, Liu Y, Wu Q, Gheiratmand L, Comartin D, Tkach JM, Cheung SW, Bashkurov M, Hasegan M, Knight JD, Lin ZY, Schueler M, Hildebrandt F, Moffat J, Gingras AC, Raught B, Pelletier L
Cell163(6)1484-99(2015 Dec)

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Emond MJ, Louie T, Emerson J, Zhao W, Mathias RA, Knowles MR, Wright FA, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC, , , Gibson RL, Bamshad MJ
Nature genetics44(8)886-9(2012 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings provide evidence that DCTN4 missense variants, especially p.Tyr263Cys, may be involved in the pathogenesis of chronic Pseudomonas aeruginosa infection in male with cystic fi brosis.
Title: DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.

used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis
Title: Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.

ATP7B interaction with p62 is a key component of the copper-induced trafficking pathway that delivers ATP7B to subapical vesicles of hepatocytes for the removal of excess copper into bile
Title: Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A.

The following DCTN4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DCTN4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31940	NM_001135643.1 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu07236	NM_016221.3 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu31892	NM_001135644.1 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu31892	XM_011537644.1 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu31892	XM_011537645.1 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu39875	XM_011537647.1 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu39875	XM_005268457.1 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu67726	XM_011537646.1 Latest version!	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DCTN4 ( NM_001135643.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129115.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu31940
Clone ID Related Accession (Same CDS sequence)	NM_001135643.1
Accession Version	NM_001135643.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC321382.1, AK307757.1 and AL162085.1. Transcript Variant: This variant (1) encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.115820.1, SRR1803611.112564.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCT TGCTGCAGTC GGACCGGGTT CTCTATCTAG TCCAGGGAGA AAAGAAGGTT 
CGGGCCCCGC TCTCGCAACT CTACTTCTGC CGCTATTGTA GCGAACTGCG GTCGCTGGAA 
TGTGTGTCTC ACGAGGTGGA CTCCCATTAT TGTCCCAGTT GTTTAGAAAA TATGCCATCG 
GCTGAAGCCA AACTAAAAAA GAATAGATGT GCCAATTGTT TTGACTGTCC TGGCTGCATG 
CACACCCTCT CTACTCGGGC CACGAGCATC TCCACACAGC TTCCAGATGA CCCAGCCAAG 
ACCACCATGA AGAAAGCCTA TTACCTGGCA TGTGGATTTT GTCGCTGGAC GTCTAGAGAT 
GTGGGCATGG CAGACAAATC TGTAGCTAGT GGCGGTTGGC AGGAACCTGA AAATCCTCAC 
ACACAACGGA TGAACAAATT GATTGAATAT TACCAGCAGC TTGCTCAGAA AGAGAAGGTT 
GAGCGAGATC GCAAGAAACT GGCACGACGT AGAAACTATA TGCCTCTGGC TTTTTCGCAA 
CATACTATTC ATGTAGTGGA CAAATATGGT CTTGGAACCA GGCTTCAGCG ACCACGAGCT 
GGTGCATCCA TCAGTACCCT TGCCGGACTT TCCCTTAAAG AAGGAGAGGA TCAGAAAGAG 
ATAAAGATTG AGCCAGCTCA GGCTGTGGAT GAAGTGGAAC CTCTACCTGA AGACTATTAT 
ACAAGACCAG TAAATTTAAC AGAGGTAACA ACCCTTCAGC AGCGTCTGTT ACAGCCTGAC 
TTCCAGCCAG TCTGTGCTTC ACAGCTCTAT CCTCGCCACA AACATCTTCT GATCAAACGG 
TCCCTGCGCT GCCGTAAATG TGAACATAAT TTGAGCAAGC CAGAATTTAA CCCAACGTCA 
ATCAAATTCA AAATCCAGCT GGTCGCTGTC AATTATATTC CAGAAGTGAG AATCATGTCA 
ATTCCCAACC TTCGCTACAT GAAGGAGAGC CAGGTCCTCC TGACTCTTAC AAATCCAGTT 
GAGAACCTCA CCCATGTGAC TCTCTTCGAG TGTGAGGAGG GGGACCCTGA TGATATCAAC 
AGCACTGCTA AGGTGGTGGT GCCTCCCAAA GAGCTCGTTT TAGCTGGCAA GGATGCAGCA 
GCAGAGTACG ATGAGTTGGC AGAACCTCAA GACTTTCAGG ACGATCCTGA CATTATAGCC 
TTCAGAAAGG CCAACAAAGT GGGTATTTTC ATCAAAGTTA CACCACAGCG TGAGGAGGGT 
GAAGTGACCG TGTGCTTCAA GATGAAGCAT GATTTTAAAA ACCTGGCAGC CCCCATTCGC 
CCCATTGAAG AAAGTGACCA GGGAACAGAA GTCATCTGGC TCACCCAGCA TGTGGAACTT 
AGCTTGGGCC CACTTCTTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129115.1
CDS	103..1506
Translation	MASLLQSDRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSQHTIHVVDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	NM_001135643.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135643.1

ORF Insert Sequence:

ATGGCGTCCT TGCTGCAGTC GGACCGGGTT CTCTATCTAG TCCAGGGAGA AAAGAAGGTT 
CGGGCCCCGC TCTCGCAACT CTACTTCTGC CGCTATTGTA GCGAACTGCG GTCGCTGGAA 
TGTGTGTCTC ACGAGGTGGA CTCCCATTAT TGTCCCAGTT GTTTAGAAAA TATGCCATCG 
GCTGAAGCCA AACTAAAAAA GAATAGATGT GCCAATTGTT TTGACTGTCC TGGCTGCATG 
CACACCCTCT CTACTCGGGC CACGAGCATC TCCACACAGC TTCCAGATGA CCCAGCCAAG 
ACCACCATGA AGAAAGCCTA TTACCTGGCA TGTGGATTTT GTCGCTGGAC GTCTAGAGAT 
GTGGGCATGG CAGACAAATC TGTAGCTAGT GGCGGTTGGC AGGAACCTGA AAATCCTCAC 
ACACAACGGA TGAACAAATT GATTGAATAT TACCAGCAGC TTGCTCAGAA AGAGAAGGTT 
GAGCGAGATC GCAAGAAACT GGCACGACGT AGAAACTATA TGCCTCTGGC TTTTTCGCAA 
CATACTATTC ATGTAGTGGA CAAATATGGT CTTGGAACCA GGCTTCAGCG ACCACGAGCT 
GGTGCATCCA TCAGTACCCT TGCCGGACTT TCCCTTAAAG AAGGAGAGGA TCAGAAAGAG 
ATAAAGATTG AGCCAGCTCA GGCTGTGGAT GAAGTGGAAC CTCTACCTGA AGACTATTAT 
ACAAGACCAG TAAATTTAAC AGAGGTAACA ACCCTTCAGC AGCGTCTGTT ACAGCCTGAC 
TTCCAGCCAG TCTGTGCTTC ACAGCTCTAT CCTCGCCACA AACATCTTCT GATCAAACGG 
TCCCTGCGCT GCCGTAAATG TGAACATAAT TTGAGCAAGC CAGAATTTAA CCCAACGTCA 
ATCAAATTCA AAATCCAGCT GGTCGCTGTC AATTATATTC CAGAAGTGAG AATCATGTCA 
ATTCCCAACC TTCGCTACAT GAAGGAGAGC CAGGTCCTCC TGACTCTTAC AAATCCAGTT 
GAGAACCTCA CCCATGTGAC TCTCTTCGAG TGTGAGGAGG GGGACCCTGA TGATATCAAC 
AGCACTGCTA AGGTGGTGGT GCCTCCCAAA GAGCTCGTTT TAGCTGGCAA GGATGCAGCA 
GCAGAGTACG ATGAGTTGGC AGAACCTCAA GACTTTCAGG ACGATCCTGA CATTATAGCC 
TTCAGAAAGG CCAACAAAGT GGGTATTTTC ATCAAAGTTA CACCACAGCG TGAGGAGGGT 
GAAGTGACCG TGTGCTTCAA GATGAAGCAT GATTTTAAAA ACCTGGCAGC CCCCATTCGC 
CCCATTGAAG AAAGTGACCA GGGAACAGAA GTCATCTGGC TCACCCAGCA TGTGGAACTT 
AGCTTGGGCC CACTTCTTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCTN4 ( NM_016221.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057305.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07236
Clone ID Related Accession (Same CDS sequence)	NM_016221.3
Accession Version	NM_016221.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC321382.1, AK000299.1 and AL162085.1. On Oct 3, 2008 this sequence version replaced NM_016221.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK000299.1, SRR1803617.72610.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCT TGCTGCAGTC GGACCGGGTT CTCTATCTAG TCCAGGGAGA AAAGAAGGTT 
CGGGCCCCGC TCTCGCAACT CTACTTCTGC CGCTATTGTA GCGAACTGCG GTCGCTGGAA 
TGTGTGTCTC ACGAGGTGGA CTCCCATTAT TGTCCCAGTT GTTTAGAAAA TATGCCATCG 
GCTGAAGCCA AACTAAAAAA GAATAGATGT GCCAATTGTT TTGACTGTCC TGGCTGCATG 
CACACCCTCT CTACTCGGGC CACGAGCATC TCCACACAGC TTCCAGATGA CCCAGCCAAG 
ACCACCATGA AGAAAGCCTA TTACCTGGCA TGTGGATTTT GTCGCTGGAC GTCTAGAGAT 
GTGGGCATGG CAGACAAATC TGTAGCTAGT GGCGGTTGGC AGGAACCTGA AAATCCTCAC 
ACACAACGGA TGAACAAATT GATTGAATAT TACCAGCAGC TTGCTCAGAA AGAGAAGGTT 
GAGCGAGATC GCAAGAAACT GGCACGACGT AGAAACTATA TGCCTCTGGC TTTTTCGGAC 
AAATATGGTC TTGGAACCAG GCTTCAGCGA CCACGAGCTG GTGCATCCAT CAGTACCCTT 
GCCGGACTTT CCCTTAAAGA AGGAGAGGAT CAGAAAGAGA TAAAGATTGA GCCAGCTCAG 
GCTGTGGATG AAGTGGAACC TCTACCTGAA GACTATTATA CAAGACCAGT AAATTTAACA 
GAGGTAACAA CCCTTCAGCA GCGTCTGTTA CAGCCTGACT TCCAGCCAGT CTGTGCTTCA 
CAGCTCTATC CTCGCCACAA ACATCTTCTG ATCAAACGGT CCCTGCGCTG CCGTAAATGT 
GAACATAATT TGAGCAAGCC AGAATTTAAC CCAACGTCAA TCAAATTCAA AATCCAGCTG 
GTCGCTGTCA ATTATATTCC AGAAGTGAGA ATCATGTCAA TTCCCAACCT TCGCTACATG 
AAGGAGAGCC AGGTCCTCCT GACTCTTACA AATCCAGTTG AGAACCTCAC CCATGTGACT 
CTCTTCGAGT GTGAGGAGGG GGACCCTGAT GATATCAACA GCACTGCTAA GGTGGTGGTG 
CCTCCCAAAG AGCTCGTTTT AGCTGGCAAG GATGCAGCAG CAGAGTACGA TGAGTTGGCA 
GAACCTCAAG ACTTTCAGGA CGATCCTGAC ATTATAGCCT TCAGAAAGGC CAACAAAGTG 
GGTATTTTCA TCAAAGTTAC ACCACAGCGT GAGGAGGGTG AAGTGACCGT GTGCTTCAAG 
ATGAAGCATG ATTTTAAAAA CCTGGCAGCC CCCATTCGCC CCATTGAAGA AAGTGACCAG 
GGAACAGAAG TCATCTGGCT CACCCAGCAT GTGGAACTTA GCTTGGGCCC ACTTCTTCCT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057305.1
CDS	103..1485
Translation	MASLLQSDRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	NM_016221.3
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016221.3

ORF Insert Sequence:

ATGGCGTCCT TGCTGCAGTC GGACCGGGTT CTCTATCTAG TCCAGGGAGA AAAGAAGGTT 
CGGGCCCCGC TCTCGCAACT CTACTTCTGC CGCTATTGTA GCGAACTGCG GTCGCTGGAA 
TGTGTGTCTC ACGAGGTGGA CTCCCATTAT TGTCCCAGTT GTTTAGAAAA TATGCCATCG 
GCTGAAGCCA AACTAAAAAA GAATAGATGT GCCAATTGTT TTGACTGTCC TGGCTGCATG 
CACACCCTCT CTACTCGGGC CACGAGCATC TCCACACAGC TTCCAGATGA CCCAGCCAAG 
ACCACCATGA AGAAAGCCTA TTACCTGGCA TGTGGATTTT GTCGCTGGAC GTCTAGAGAT 
GTGGGCATGG CAGACAAATC TGTAGCTAGT GGCGGTTGGC AGGAACCTGA AAATCCTCAC 
ACACAACGGA TGAACAAATT GATTGAATAT TACCAGCAGC TTGCTCAGAA AGAGAAGGTT 
GAGCGAGATC GCAAGAAACT GGCACGACGT AGAAACTATA TGCCTCTGGC TTTTTCGGAC 
AAATATGGTC TTGGAACCAG GCTTCAGCGA CCACGAGCTG GTGCATCCAT CAGTACCCTT 
GCCGGACTTT CCCTTAAAGA AGGAGAGGAT CAGAAAGAGA TAAAGATTGA GCCAGCTCAG 
GCTGTGGATG AAGTGGAACC TCTACCTGAA GACTATTATA CAAGACCAGT AAATTTAACA 
GAGGTAACAA CCCTTCAGCA GCGTCTGTTA CAGCCTGACT TCCAGCCAGT CTGTGCTTCA 
CAGCTCTATC CTCGCCACAA ACATCTTCTG ATCAAACGGT CCCTGCGCTG CCGTAAATGT 
GAACATAATT TGAGCAAGCC AGAATTTAAC CCAACGTCAA TCAAATTCAA AATCCAGCTG 
GTCGCTGTCA ATTATATTCC AGAAGTGAGA ATCATGTCAA TTCCCAACCT TCGCTACATG 
AAGGAGAGCC AGGTCCTCCT GACTCTTACA AATCCAGTTG AGAACCTCAC CCATGTGACT 
CTCTTCGAGT GTGAGGAGGG GGACCCTGAT GATATCAACA GCACTGCTAA GGTGGTGGTG 
CCTCCCAAAG AGCTCGTTTT AGCTGGCAAG GATGCAGCAG CAGAGTACGA TGAGTTGGCA 
GAACCTCAAG ACTTTCAGGA CGATCCTGAC ATTATAGCCT TCAGAAAGGC CAACAAAGTG 
GGTATTTTCA TCAAAGTTAC ACCACAGCGT GAGGAGGGTG AAGTGACCGT GTGCTTCAAG 
ATGAAGCATG ATTTTAAAAA CCTGGCAGCC CCCATTCGCC CCATTGAAGA AAGTGACCAG 
GGAACAGAAG TCATCTGGCT CACCCAGCAT GTGGAACTTA GCTTGGGCCC ACTTCTTCCT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCTN4 ( NM_001135644.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129116.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu31892
Clone ID Related Accession (Same CDS sequence)	NM_001135644.1 , XM_011537644.1 , XM_011537645.1
Accession Version	NM_001135644.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK125973.1, AC008450.5 and AL162085.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) is shorter at the N-terminus and lacks a 7 aa internal segment compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK125973.1, SRR1660803.245224.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCATCGG CTGAAGCCAA ACTAAAAAAG AATAGATGTG CCAATTGTTT TGACTGTCCT 
GGCTGCATGC ACACCCTCTC TACTCGGGCC ACGAGCATCT CCACACAGCT TCCAGATGAC 
CCAGCCAAGA CCACCATGAA GAAAGCCTAT TACCTGGCAT GTGGATTTTG TCGCTGGACG 
TCTAGAGATG TGGGCATGGC AGACAAATCT GTAGCTAGTG GCGGTTGGCA GGAACCTGAA 
AATCCTCACA CACAACGGAT GAACAAATTG ATTGAATATT ACCAGCAGCT TGCTCAGAAA 
GAGAAGGTTG AGCGAGATCG CAAGAAACTG GCACGACGTA GAAACTATAT GCCTCTGGCT 
TTTTCGGACA AATATGGTCT TGGAACCAGG CTTCAGCGAC CACGAGCTGG TGCATCCATC 
AGTACCCTTG CCGGACTTTC CCTTAAAGAA GGAGAGGATC AGAAAGAGAT AAAGATTGAG 
CCAGCTCAGG CTGTGGATGA AGTGGAACCT CTACCTGAAG ACTATTATAC AAGACCAGTA 
AATTTAACAG AGGTAACAAC CCTTCAGCAG CGTCTGTTAC AGCCTGACTT CCAGCCAGTC 
TGTGCTTCAC AGCTCTATCC TCGCCACAAA CATCTTCTGA TCAAACGGTC CCTGCGCTGC 
CGTAAATGTG AACATAATTT GAGCAAGCCA GAATTTAACC CAACGTCAAT CAAATTCAAA 
ATCCAGCTGG TCGCTGTCAA TTATATTCCA GAAGTGAGAA TCATGTCAAT TCCCAACCTT 
CGCTACATGA AGGAGAGCCA GGTCCTCCTG ACTCTTACAA ATCCAGTTGA GAACCTCACC 
CATGTGACTC TCTTCGAGTG TGAGGAGGGG GACCCTGATG ATATCAACAG CACTGCTAAG 
GTGGTGGTGC CTCCCAAAGA GCTCGTTTTA GCTGGCAAGG ATGCAGCAGC AGAGTACGAT 
GAGTTGGCAG AACCTCAAGA CTTTCAGGAC GATCCTGACA TTATAGCCTT CAGAAAGGCC 
AACAAAGTGG GTATTTTCAT CAAAGTTACA CCACAGCGTG AGGAGGGTGA AGTGACCGTG 
TGCTTCAAGA TGAAGCATGA TTTTAAAAAC CTGGCAGCCC CCATTCGCCC CATTGAAGAA 
AGTGACCAGG GAACAGAAGT CATCTGGCTC ACCCAGCATG TGGAACTTAG CTTGGGCCCA 
CTTCTTCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129116.1
CDS	442..1653
Translation	MPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	NM_001135644.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135644.1

ORF Insert Sequence:

ATGCCATCGG CTGAAGCCAA ACTAAAAAAG AATAGATGTG CCAATTGTTT TGACTGTCCT 
GGCTGCATGC ACACCCTCTC TACTCGGGCC ACGAGCATCT CCACACAGCT TCCAGATGAC 
CCAGCCAAGA CCACCATGAA GAAAGCCTAT TACCTGGCAT GTGGATTTTG TCGCTGGACG 
TCTAGAGATG TGGGCATGGC AGACAAATCT GTAGCTAGTG GCGGTTGGCA GGAACCTGAA 
AATCCTCACA CACAACGGAT GAACAAATTG ATTGAATATT ACCAGCAGCT TGCTCAGAAA 
GAGAAGGTTG AGCGAGATCG CAAGAAACTG GCACGACGTA GAAACTATAT GCCTCTGGCT 
TTTTCGGACA AATATGGTCT TGGAACCAGG CTTCAGCGAC CACGAGCTGG TGCATCCATC 
AGTACCCTTG CCGGACTTTC CCTTAAAGAA GGAGAGGATC AGAAAGAGAT AAAGATTGAG 
CCAGCTCAGG CTGTGGATGA AGTGGAACCT CTACCTGAAG ACTATTATAC AAGACCAGTA 
AATTTAACAG AGGTAACAAC CCTTCAGCAG CGTCTGTTAC AGCCTGACTT CCAGCCAGTC 
TGTGCTTCAC AGCTCTATCC TCGCCACAAA CATCTTCTGA TCAAACGGTC CCTGCGCTGC 
CGTAAATGTG AACATAATTT GAGCAAGCCA GAATTTAACC CAACGTCAAT CAAATTCAAA 
ATCCAGCTGG TCGCTGTCAA TTATATTCCA GAAGTGAGAA TCATGTCAAT TCCCAACCTT 
CGCTACATGA AGGAGAGCCA GGTCCTCCTG ACTCTTACAA ATCCAGTTGA GAACCTCACC 
CATGTGACTC TCTTCGAGTG TGAGGAGGGG GACCCTGATG ATATCAACAG CACTGCTAAG 
GTGGTGGTGC CTCCCAAAGA GCTCGTTTTA GCTGGCAAGG ATGCAGCAGC AGAGTACGAT 
GAGTTGGCAG AACCTCAAGA CTTTCAGGAC GATCCTGACA TTATAGCCTT CAGAAAGGCC 
AACAAAGTGG GTATTTTCAT CAAAGTTACA CCACAGCGTG AGGAGGGTGA AGTGACCGTG 
TGCTTCAAGA TGAAGCATGA TTTTAAAAAC CTGGCAGCCC CCATTCGCCC CATTGAAGAA 
AGTGACCAGG GAACAGAAGT CATCTGGCTC ACCCAGCATG TGGAACTTAG CTTGGGCCCA 
CTTCTTCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCTN4 ( XM_011537644.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011535946.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu31892
Clone ID Related Accession (Same CDS sequence)	NM_001135644.1 , XM_011537644.1 , XM_011537645.1
Accession Version	XM_011537644.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCATCGG CTGAAGCCAA ACTAAAAAAG AATAGATGTG CCAATTGTTT TGACTGTCCT 
GGCTGCATGC ACACCCTCTC TACTCGGGCC ACGAGCATCT CCACACAGCT TCCAGATGAC 
CCAGCCAAGA CCACCATGAA GAAAGCCTAT TACCTGGCAT GTGGATTTTG TCGCTGGACG 
TCTAGAGATG TGGGCATGGC AGACAAATCT GTAGCTAGTG GCGGTTGGCA GGAACCTGAA 
AATCCTCACA CACAACGGAT GAACAAATTG ATTGAATATT ACCAGCAGCT TGCTCAGAAA 
GAGAAGGTTG AGCGAGATCG CAAGAAACTG GCACGACGTA GAAACTATAT GCCTCTGGCT 
TTTTCGGACA AATATGGTCT TGGAACCAGG CTTCAGCGAC CACGAGCTGG TGCATCCATC 
AGTACCCTTG CCGGACTTTC CCTTAAAGAA GGAGAGGATC AGAAAGAGAT AAAGATTGAG 
CCAGCTCAGG CTGTGGATGA AGTGGAACCT CTACCTGAAG ACTATTATAC AAGACCAGTA 
AATTTAACAG AGGTAACAAC CCTTCAGCAG CGTCTGTTAC AGCCTGACTT CCAGCCAGTC 
TGTGCTTCAC AGCTCTATCC TCGCCACAAA CATCTTCTGA TCAAACGGTC CCTGCGCTGC 
CGTAAATGTG AACATAATTT GAGCAAGCCA GAATTTAACC CAACGTCAAT CAAATTCAAA 
ATCCAGCTGG TCGCTGTCAA TTATATTCCA GAAGTGAGAA TCATGTCAAT TCCCAACCTT 
CGCTACATGA AGGAGAGCCA GGTCCTCCTG ACTCTTACAA ATCCAGTTGA GAACCTCACC 
CATGTGACTC TCTTCGAGTG TGAGGAGGGG GACCCTGATG ATATCAACAG CACTGCTAAG 
GTGGTGGTGC CTCCCAAAGA GCTCGTTTTA GCTGGCAAGG ATGCAGCAGC AGAGTACGAT 
GAGTTGGCAG AACCTCAAGA CTTTCAGGAC GATCCTGACA TTATAGCCTT CAGAAAGGCC 
AACAAAGTGG GTATTTTCAT CAAAGTTACA CCACAGCGTG AGGAGGGTGA AGTGACCGTG 
TGCTTCAAGA TGAAGCATGA TTTTAAAAAC CTGGCAGCCC CCATTCGCCC CATTGAAGAA 
AGTGACCAGG GAACAGAAGT CATCTGGCTC ACCCAGCATG TGGAACTTAG CTTGGGCCCA 
CTTCTTCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011535946.1
CDS	178..1389
Translation	MPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	XM_011537644.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537644.1

ORF Insert Sequence:

ATGCCATCGG CTGAAGCCAA ACTAAAAAAG AATAGATGTG CCAATTGTTT TGACTGTCCT 
GGCTGCATGC ACACCCTCTC TACTCGGGCC ACGAGCATCT CCACACAGCT TCCAGATGAC 
CCAGCCAAGA CCACCATGAA GAAAGCCTAT TACCTGGCAT GTGGATTTTG TCGCTGGACG 
TCTAGAGATG TGGGCATGGC AGACAAATCT GTAGCTAGTG GCGGTTGGCA GGAACCTGAA 
AATCCTCACA CACAACGGAT GAACAAATTG ATTGAATATT ACCAGCAGCT TGCTCAGAAA 
GAGAAGGTTG AGCGAGATCG CAAGAAACTG GCACGACGTA GAAACTATAT GCCTCTGGCT 
TTTTCGGACA AATATGGTCT TGGAACCAGG CTTCAGCGAC CACGAGCTGG TGCATCCATC 
AGTACCCTTG CCGGACTTTC CCTTAAAGAA GGAGAGGATC AGAAAGAGAT AAAGATTGAG 
CCAGCTCAGG CTGTGGATGA AGTGGAACCT CTACCTGAAG ACTATTATAC AAGACCAGTA 
AATTTAACAG AGGTAACAAC CCTTCAGCAG CGTCTGTTAC AGCCTGACTT CCAGCCAGTC 
TGTGCTTCAC AGCTCTATCC TCGCCACAAA CATCTTCTGA TCAAACGGTC CCTGCGCTGC 
CGTAAATGTG AACATAATTT GAGCAAGCCA GAATTTAACC CAACGTCAAT CAAATTCAAA 
ATCCAGCTGG TCGCTGTCAA TTATATTCCA GAAGTGAGAA TCATGTCAAT TCCCAACCTT 
CGCTACATGA AGGAGAGCCA GGTCCTCCTG ACTCTTACAA ATCCAGTTGA GAACCTCACC 
CATGTGACTC TCTTCGAGTG TGAGGAGGGG GACCCTGATG ATATCAACAG CACTGCTAAG 
GTGGTGGTGC CTCCCAAAGA GCTCGTTTTA GCTGGCAAGG ATGCAGCAGC AGAGTACGAT 
GAGTTGGCAG AACCTCAAGA CTTTCAGGAC GATCCTGACA TTATAGCCTT CAGAAAGGCC 
AACAAAGTGG GTATTTTCAT CAAAGTTACA CCACAGCGTG AGGAGGGTGA AGTGACCGTG 
TGCTTCAAGA TGAAGCATGA TTTTAAAAAC CTGGCAGCCC CCATTCGCCC CATTGAAGAA 
AGTGACCAGG GAACAGAAGT CATCTGGCTC ACCCAGCATG TGGAACTTAG CTTGGGCCCA 
CTTCTTCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCTN4 ( XM_011537645.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011535947.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu31892
Clone ID Related Accession (Same CDS sequence)	NM_001135644.1 , XM_011537644.1 , XM_011537645.1
Accession Version	XM_011537645.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCATCGG CTGAAGCCAA ACTAAAAAAG AATAGATGTG CCAATTGTTT TGACTGTCCT 
GGCTGCATGC ACACCCTCTC TACTCGGGCC ACGAGCATCT CCACACAGCT TCCAGATGAC 
CCAGCCAAGA CCACCATGAA GAAAGCCTAT TACCTGGCAT GTGGATTTTG TCGCTGGACG 
TCTAGAGATG TGGGCATGGC AGACAAATCT GTAGCTAGTG GCGGTTGGCA GGAACCTGAA 
AATCCTCACA CACAACGGAT GAACAAATTG ATTGAATATT ACCAGCAGCT TGCTCAGAAA 
GAGAAGGTTG AGCGAGATCG CAAGAAACTG GCACGACGTA GAAACTATAT GCCTCTGGCT 
TTTTCGGACA AATATGGTCT TGGAACCAGG CTTCAGCGAC CACGAGCTGG TGCATCCATC 
AGTACCCTTG CCGGACTTTC CCTTAAAGAA GGAGAGGATC AGAAAGAGAT AAAGATTGAG 
CCAGCTCAGG CTGTGGATGA AGTGGAACCT CTACCTGAAG ACTATTATAC AAGACCAGTA 
AATTTAACAG AGGTAACAAC CCTTCAGCAG CGTCTGTTAC AGCCTGACTT CCAGCCAGTC 
TGTGCTTCAC AGCTCTATCC TCGCCACAAA CATCTTCTGA TCAAACGGTC CCTGCGCTGC 
CGTAAATGTG AACATAATTT GAGCAAGCCA GAATTTAACC CAACGTCAAT CAAATTCAAA 
ATCCAGCTGG TCGCTGTCAA TTATATTCCA GAAGTGAGAA TCATGTCAAT TCCCAACCTT 
CGCTACATGA AGGAGAGCCA GGTCCTCCTG ACTCTTACAA ATCCAGTTGA GAACCTCACC 
CATGTGACTC TCTTCGAGTG TGAGGAGGGG GACCCTGATG ATATCAACAG CACTGCTAAG 
GTGGTGGTGC CTCCCAAAGA GCTCGTTTTA GCTGGCAAGG ATGCAGCAGC AGAGTACGAT 
GAGTTGGCAG AACCTCAAGA CTTTCAGGAC GATCCTGACA TTATAGCCTT CAGAAAGGCC 
AACAAAGTGG GTATTTTCAT CAAAGTTACA CCACAGCGTG AGGAGGGTGA AGTGACCGTG 
TGCTTCAAGA TGAAGCATGA TTTTAAAAAC CTGGCAGCCC CCATTCGCCC CATTGAAGAA 
AGTGACCAGG GAACAGAAGT CATCTGGCTC ACCCAGCATG TGGAACTTAG CTTGGGCCCA 
CTTCTTCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011535947.1
CDS	90..1301
Translation	MPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	XM_011537645.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537645.1

ORF Insert Sequence:

ATGCCATCGG CTGAAGCCAA ACTAAAAAAG AATAGATGTG CCAATTGTTT TGACTGTCCT 
GGCTGCATGC ACACCCTCTC TACTCGGGCC ACGAGCATCT CCACACAGCT TCCAGATGAC 
CCAGCCAAGA CCACCATGAA GAAAGCCTAT TACCTGGCAT GTGGATTTTG TCGCTGGACG 
TCTAGAGATG TGGGCATGGC AGACAAATCT GTAGCTAGTG GCGGTTGGCA GGAACCTGAA 
AATCCTCACA CACAACGGAT GAACAAATTG ATTGAATATT ACCAGCAGCT TGCTCAGAAA 
GAGAAGGTTG AGCGAGATCG CAAGAAACTG GCACGACGTA GAAACTATAT GCCTCTGGCT 
TTTTCGGACA AATATGGTCT TGGAACCAGG CTTCAGCGAC CACGAGCTGG TGCATCCATC 
AGTACCCTTG CCGGACTTTC CCTTAAAGAA GGAGAGGATC AGAAAGAGAT AAAGATTGAG 
CCAGCTCAGG CTGTGGATGA AGTGGAACCT CTACCTGAAG ACTATTATAC AAGACCAGTA 
AATTTAACAG AGGTAACAAC CCTTCAGCAG CGTCTGTTAC AGCCTGACTT CCAGCCAGTC 
TGTGCTTCAC AGCTCTATCC TCGCCACAAA CATCTTCTGA TCAAACGGTC CCTGCGCTGC 
CGTAAATGTG AACATAATTT GAGCAAGCCA GAATTTAACC CAACGTCAAT CAAATTCAAA 
ATCCAGCTGG TCGCTGTCAA TTATATTCCA GAAGTGAGAA TCATGTCAAT TCCCAACCTT 
CGCTACATGA AGGAGAGCCA GGTCCTCCTG ACTCTTACAA ATCCAGTTGA GAACCTCACC 
CATGTGACTC TCTTCGAGTG TGAGGAGGGG GACCCTGATG ATATCAACAG CACTGCTAAG 
GTGGTGGTGC CTCCCAAAGA GCTCGTTTTA GCTGGCAAGG ATGCAGCAGC AGAGTACGAT 
GAGTTGGCAG AACCTCAAGA CTTTCAGGAC GATCCTGACA TTATAGCCTT CAGAAAGGCC 
AACAAAGTGG GTATTTTCAT CAAAGTTACA CCACAGCGTG AGGAGGGTGA AGTGACCGTG 
TGCTTCAAGA TGAAGCATGA TTTTAAAAAC CTGGCAGCCC CCATTCGCCC CATTGAAGAA 
AGTGACCAGG GAACAGAAGT CATCTGGCTC ACCCAGCATG TGGAACTTAG CTTGGGCCCA 
CTTCTTCCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCTN4 ( XM_011537647.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011535949.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu39875
Clone ID Related Accession (Same CDS sequence)	XM_011537647.1 , XM_005268457.1
Accession Version	XM_011537647.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAT TGATTGAATA TTACCAGCAG CTTGCTCAGA AAGAGAAGGT TGAGCGAGAT 
CGCAAGAAAC TGGCACGACG TAGAAACTAT ATGCCTCTGG CTTTTTCGGA CAAATATGGT 
CTTGGAACCA GGCTTCAGCG ACCACGAGCT GGTGCATCCA TCAGTACCCT TGCCGGACTT 
TCCCTTAAAG AAGGAGAGGA TCAGAAAGAG ATAAAGATTG AGCCAGCTCA GGCTGTGGAT 
GAAGTGGAAC CTCTACCTGA AGACTATTAT ACAAGACCAG TAAATTTAAC AGAGGTAACA 
ACCCTTCAGC AGCGTCTGTT ACAGCCTGAC TTCCAGCCAG TCTGTGCTTC ACAGCTCTAT 
CCTCGCCACA AACATCTTCT GATCAAACGG TCCCTGCGCT GCCGTAAATG TGAACATAAT 
TTGAGCAAGC CAGAATTTAA CCCAACGTCA ATCAAATTCA AAATCCAGCT GGTCGCTGTC 
AATTATATTC CAGAAGTGAG AATCATGTCA ATTCCCAACC TTCGCTACAT GAAGGAGAGC 
CAGGTCCTCC TGACTCTTAC AAATCCAGTT GAGAACCTCA CCCATGTGAC TCTCTTCGAG 
TGTGAGGAGG GGGACCCTGA TGATATCAAC AGCACTGCTA AGGTGGTGGT GCCTCCCAAA 
GAGCTCGTTT TAGCTGGCAA GGATGCAGCA GCAGAGTACG ATGAGTTGGC AGAACCTCAA 
GACTTTCAGG ACGATCCTGA CATTATAGCC TTCAGAAAGG CCAACAAAGT GGGTATTTTC 
ATCAAAGTTA CACCACAGCG TGAGGAGGGT GAAGTGACCG TGTGCTTCAA GATGAAGCAT 
GATTTTAAAA ACCTGGCAGC CCCCATTCGC CCCATTGAAG AAAGTGACCA GGGAACAGAA 
GTCATCTGGC TCACCCAGCA TGTGGAACTT AGCTTGGGCC CACTTCTTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011535949.1
CDS	392..1345
Translation	MNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	XM_011537647.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537647.1

ORF Insert Sequence:

ATGAACAAAT TGATTGAATA TTACCAGCAG CTTGCTCAGA AAGAGAAGGT TGAGCGAGAT 
CGCAAGAAAC TGGCACGACG TAGAAACTAT ATGCCTCTGG CTTTTTCGGA CAAATATGGT 
CTTGGAACCA GGCTTCAGCG ACCACGAGCT GGTGCATCCA TCAGTACCCT TGCCGGACTT 
TCCCTTAAAG AAGGAGAGGA TCAGAAAGAG ATAAAGATTG AGCCAGCTCA GGCTGTGGAT 
GAAGTGGAAC CTCTACCTGA AGACTATTAT ACAAGACCAG TAAATTTAAC AGAGGTAACA 
ACCCTTCAGC AGCGTCTGTT ACAGCCTGAC TTCCAGCCAG TCTGTGCTTC ACAGCTCTAT 
CCTCGCCACA AACATCTTCT GATCAAACGG TCCCTGCGCT GCCGTAAATG TGAACATAAT 
TTGAGCAAGC CAGAATTTAA CCCAACGTCA ATCAAATTCA AAATCCAGCT GGTCGCTGTC 
AATTATATTC CAGAAGTGAG AATCATGTCA ATTCCCAACC TTCGCTACAT GAAGGAGAGC 
CAGGTCCTCC TGACTCTTAC AAATCCAGTT GAGAACCTCA CCCATGTGAC TCTCTTCGAG 
TGTGAGGAGG GGGACCCTGA TGATATCAAC AGCACTGCTA AGGTGGTGGT GCCTCCCAAA 
GAGCTCGTTT TAGCTGGCAA GGATGCAGCA GCAGAGTACG ATGAGTTGGC AGAACCTCAA 
GACTTTCAGG ACGATCCTGA CATTATAGCC TTCAGAAAGG CCAACAAAGT GGGTATTTTC 
ATCAAAGTTA CACCACAGCG TGAGGAGGGT GAAGTGACCG TGTGCTTCAA GATGAAGCAT 
GATTTTAAAA ACCTGGCAGC CCCCATTCGC CCCATTGAAG AAAGTGACCA GGGAACAGAA 
GTCATCTGGC TCACCCAGCA TGTGGAACTT AGCTTGGGCC CACTTCTTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCTN4 ( XM_005268457.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268514.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu39875
Clone ID Related Accession (Same CDS sequence)	XM_011537647.1 , XM_005268457.1
Accession Version	XM_005268457.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAT TGATTGAATA TTACCAGCAG CTTGCTCAGA AAGAGAAGGT TGAGCGAGAT 
CGCAAGAAAC TGGCACGACG TAGAAACTAT ATGCCTCTGG CTTTTTCGGA CAAATATGGT 
CTTGGAACCA GGCTTCAGCG ACCACGAGCT GGTGCATCCA TCAGTACCCT TGCCGGACTT 
TCCCTTAAAG AAGGAGAGGA TCAGAAAGAG ATAAAGATTG AGCCAGCTCA GGCTGTGGAT 
GAAGTGGAAC CTCTACCTGA AGACTATTAT ACAAGACCAG TAAATTTAAC AGAGGTAACA 
ACCCTTCAGC AGCGTCTGTT ACAGCCTGAC TTCCAGCCAG TCTGTGCTTC ACAGCTCTAT 
CCTCGCCACA AACATCTTCT GATCAAACGG TCCCTGCGCT GCCGTAAATG TGAACATAAT 
TTGAGCAAGC CAGAATTTAA CCCAACGTCA ATCAAATTCA AAATCCAGCT GGTCGCTGTC 
AATTATATTC CAGAAGTGAG AATCATGTCA ATTCCCAACC TTCGCTACAT GAAGGAGAGC 
CAGGTCCTCC TGACTCTTAC AAATCCAGTT GAGAACCTCA CCCATGTGAC TCTCTTCGAG 
TGTGAGGAGG GGGACCCTGA TGATATCAAC AGCACTGCTA AGGTGGTGGT GCCTCCCAAA 
GAGCTCGTTT TAGCTGGCAA GGATGCAGCA GCAGAGTACG ATGAGTTGGC AGAACCTCAA 
GACTTTCAGG ACGATCCTGA CATTATAGCC TTCAGAAAGG CCAACAAAGT GGGTATTTTC 
ATCAAAGTTA CACCACAGCG TGAGGAGGGT GAAGTGACCG TGTGCTTCAA GATGAAGCAT 
GATTTTAAAA ACCTGGCAGC CCCCATTCGC CCCATTGAAG AAAGTGACCA GGGAACAGAA 
GTCATCTGGC TCACCCAGCA TGTGGAACTT AGCTTGGGCC CACTTCTTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268514.1
CDS	426..1379
Translation	MNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	XM_005268457.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268457.1

ORF Insert Sequence:

ATGAACAAAT TGATTGAATA TTACCAGCAG CTTGCTCAGA AAGAGAAGGT TGAGCGAGAT 
CGCAAGAAAC TGGCACGACG TAGAAACTAT ATGCCTCTGG CTTTTTCGGA CAAATATGGT 
CTTGGAACCA GGCTTCAGCG ACCACGAGCT GGTGCATCCA TCAGTACCCT TGCCGGACTT 
TCCCTTAAAG AAGGAGAGGA TCAGAAAGAG ATAAAGATTG AGCCAGCTCA GGCTGTGGAT 
GAAGTGGAAC CTCTACCTGA AGACTATTAT ACAAGACCAG TAAATTTAAC AGAGGTAACA 
ACCCTTCAGC AGCGTCTGTT ACAGCCTGAC TTCCAGCCAG TCTGTGCTTC ACAGCTCTAT 
CCTCGCCACA AACATCTTCT GATCAAACGG TCCCTGCGCT GCCGTAAATG TGAACATAAT 
TTGAGCAAGC CAGAATTTAA CCCAACGTCA ATCAAATTCA AAATCCAGCT GGTCGCTGTC 
AATTATATTC CAGAAGTGAG AATCATGTCA ATTCCCAACC TTCGCTACAT GAAGGAGAGC 
CAGGTCCTCC TGACTCTTAC AAATCCAGTT GAGAACCTCA CCCATGTGAC TCTCTTCGAG 
TGTGAGGAGG GGGACCCTGA TGATATCAAC AGCACTGCTA AGGTGGTGGT GCCTCCCAAA 
GAGCTCGTTT TAGCTGGCAA GGATGCAGCA GCAGAGTACG ATGAGTTGGC AGAACCTCAA 
GACTTTCAGG ACGATCCTGA CATTATAGCC TTCAGAAAGG CCAACAAAGT GGGTATTTTC 
ATCAAAGTTA CACCACAGCG TGAGGAGGGT GAAGTGACCG TGTGCTTCAA GATGAAGCAT 
GATTTTAAAA ACCTGGCAGC CCCCATTCGC CCCATTGAAG AAAGTGACCA GGGAACAGAA 
GTCATCTGGC TCACCCAGCA TGTGGAACTT AGCTTGGGCC CACTTCTTCC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCTN4 ( XM_011537646.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011535948.1 Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X3, mRNA.

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CloneID	OHu67726
Clone ID Related Accession (Same CDS sequence)	XM_011537646.1
Accession Version	XM_011537646.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dynactin subunit 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACACCC TCTCTACTCG GGCCACGAGC ATCTCCACAC AGCTTCCAGA TGACCCAGCC 
AAGACCACCA TGAAGAAAGC CTATTACCTG GCATGTGGAT TTTGTCGCTG GACGTCTAGA 
GATGTGGGCA TGGCAGACAA ATCTGTAGCT AGTGGCGGTT GGCAGGAACC TGAAAATCCT 
CACACACAAC GGATGAACAA ATTGATTGAA TATTACCAGC AGCTTGCTCA GAAAGAGAAG 
GTTGAGCGAG ATCGCAAGAA ACTGGCACGA CGTAGAAACT ATATGCCTCT GGCTTTTTCG 
GACAAATATG GTCTTGGAAC CAGGCTTCAG CGACCACGAG CTGGTGCATC CATCAGTACC 
CTTGCCGGAC TTTCCCTTAA AGAAGGAGAG GATCAGAAAG AGATAAAGAT TGAGCCAGCT 
CAGGCTGTGG ATGAAGTGGA ACCTCTACCT GAAGACTATT ATACAAGACC AGTAAATTTA 
ACAGAGGTAA CAACCCTTCA GCAGCGTCTG TTACAGCCTG ACTTCCAGCC AGTCTGTGCT 
TCACAGCTCT ATCCTCGCCA CAAACATCTT CTGATCAAAC GGTCCCTGCG CTGCCGTAAA 
TGTGAACATA ATTTGAGCAA GCCAGAATTT AACCCAACGT CAATCAAATT CAAAATCCAG 
CTGGTCGCTG TCAATTATAT TCCAGAAGTG AGAATCATGT CAATTCCCAA CCTTCGCTAC 
ATGAAGGAGA GCCAGGTCCT CCTGACTCTT ACAAATCCAG TTGAGAACCT CACCCATGTG 
ACTCTCTTCG AGTGTGAGGA GGGGGACCCT GATGATATCA ACAGCACTGC TAAGGTGGTG 
GTGCCTCCCA AAGAGCTCGT TTTAGCTGGC AAGGATGCAG CAGCAGAGTA CGATGAGTTG 
GCAGAACCTC AAGACTTTCA GGACGATCCT GACATTATAG CCTTCAGAAA GGCCAACAAA 
GTGGGTATTT TCATCAAAGT TACACCACAG CGTGAGGAGG GTGAAGTGAC CGTGTGCTTC 
AAGATGAAGC ATGATTTTAA AAACCTGGCA GCCCCCATTC GCCCCATTGA AGAAAGTGAC 
CAGGGAACAG AAGTCATCTG GCTCACCCAG CATGTGGAAC TTAGCTTGGG CCCACTTCTT 
CCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011535948.1
CDS	377..1522
Translation	MHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP

Target ORF information:

RefSeq Version	XM_011537646.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dynactin subunit 4 (DCTN4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011537646.1

ORF Insert Sequence:

ATGCACACCC TCTCTACTCG GGCCACGAGC ATCTCCACAC AGCTTCCAGA TGACCCAGCC 
AAGACCACCA TGAAGAAAGC CTATTACCTG GCATGTGGAT TTTGTCGCTG GACGTCTAGA 
GATGTGGGCA TGGCAGACAA ATCTGTAGCT AGTGGCGGTT GGCAGGAACC TGAAAATCCT 
CACACACAAC GGATGAACAA ATTGATTGAA TATTACCAGC AGCTTGCTCA GAAAGAGAAG 
GTTGAGCGAG ATCGCAAGAA ACTGGCACGA CGTAGAAACT ATATGCCTCT GGCTTTTTCG 
GACAAATATG GTCTTGGAAC CAGGCTTCAG CGACCACGAG CTGGTGCATC CATCAGTACC 
CTTGCCGGAC TTTCCCTTAA AGAAGGAGAG GATCAGAAAG AGATAAAGAT TGAGCCAGCT 
CAGGCTGTGG ATGAAGTGGA ACCTCTACCT GAAGACTATT ATACAAGACC AGTAAATTTA 
ACAGAGGTAA CAACCCTTCA GCAGCGTCTG TTACAGCCTG ACTTCCAGCC AGTCTGTGCT 
TCACAGCTCT ATCCTCGCCA CAAACATCTT CTGATCAAAC GGTCCCTGCG CTGCCGTAAA 
TGTGAACATA ATTTGAGCAA GCCAGAATTT AACCCAACGT CAATCAAATT CAAAATCCAG 
CTGGTCGCTG TCAATTATAT TCCAGAAGTG AGAATCATGT CAATTCCCAA CCTTCGCTAC 
ATGAAGGAGA GCCAGGTCCT CCTGACTCTT ACAAATCCAG TTGAGAACCT CACCCATGTG 
ACTCTCTTCG AGTGTGAGGA GGGGGACCCT GATGATATCA ACAGCACTGC TAAGGTGGTG 
GTGCCTCCCA AAGAGCTCGT TTTAGCTGGC AAGGATGCAG CAGCAGAGTA CGATGAGTTG 
GCAGAACCTC AAGACTTTCA GGACGATCCT GACATTATAG CCTTCAGAAA GGCCAACAAA 
GTGGGTATTT TCATCAAAGT TACACCACAG CGTGAGGAGG GTGAAGTGAC CGTGTGCTTC 
AAGATGAAGC ATGATTTTAA AAACCTGGCA GCCCCCATTC GCCCCATTGA AGAAAGTGAC 
CAGGGAACAG AAGTCATCTG GCTCACCCAG CATGTGGAAC TTAGCTTGGG CCCACTTCTT 
CCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
The clinical respiratory journal10(6)777-783(2016 Nov)
Viel M,Hubert D,Burgel PR,G?nin E,Honor? I,Martinez B,Gaitch N,Chapron J,Kanaan R,Dusser D,Girodon E,Bienvenu T

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
Cell163(6)1484-99(2015 Dec)
Gupta GD,Coyaud ?,Gon?alves J,Mojarad BA,Liu Y,Wu Q,Gheiratmand L,Comartin D,Tkach JM,Cheung SW,Bashkurov M,Hasegan M,Knight JD,Lin ZY,Schueler M,Hildebrandt F,Moffat J,Gingras AC,Raught B,Pelletier L

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Nature genetics44(8)886-9(2012 Jul)
Emond MJ,Louie T,Emerson J,Zhao W,Mathias RA,Knowles MR,Wright FA,Rieder MJ,Tabor HK,Nickerson DA,Barnes KC,,,Gibson RL,Bamshad MJ

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DCTN4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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