SIDT2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SIDT2
Entrez Gene ID	51092
Full Name	SID1 transmembrane family member 2
Synonyms	CGI-40
General protein information	Preferred Names SID1 transmembrane family member 2 Names SID1 transmembrane family member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q23.3
Disorder MIM:	617551

mRNA and Protein(s)

mRNA	Protein	Name
NM_001040455.1	NP_001035545.1	SID1 transmembrane family member 2 precursor
NM_001040455.2	NP_001035545.1	SID1 transmembrane family member 2 precursor

Pathways from BioSystems

Homologies

	SIDT2	XP_001091606.2
Canis lupus familiaris (dog)	SIDT2	XP_003639075.2
Gallus gallus (chicken)	SIDT2	XP_001233566.3
Rattus norvegicus (Norway rat)	Sidt2	NP_001101612.1
Homo sapiens (human)	SIDT2	NP_001035545.1
Mus musculus (house mouse)	Sidt2	NP_758461.1
Caenorhabditis elegans (roundworm)	tag-130	NP_509489.1
Xenopus tropicalis (tropical clawed frog)	sidt2	XP_004916133.1
Pan troglodytes (chimpanzee)	SIDT2	XP_001154592.1
Bos taurus (cattle)	SIDT2	NP_001019701.2

Gene Ontology
Bibliography

Related articles in PubMed

SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells.
Takahashi M, Contu VR, Kabuta C, Hase K, Fujiwara Y, Wada K, Kabuta T
RNA biology14(11)1534-1543(2017 Nov)

A novel family of mammalian transmembrane proteins involved in cholesterol transport.
M?ndez-Acevedo KM, Valdes VJ, Asanov A, Vaca L
Scientific reports7(1)7450(2017 Aug)

Identification of Sidt2 as a lysosomal cation-conducting protein.
Beck A, Fecher-Trost C, Wolske K, Philipp SE, Flockerzi V, Wissenbach U
FEBS letters591(1)76-87(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sidt2 is located on chromosome 11q23, a locus repeatedly found by chromosomal mapping of Alzheimer's disease-related genes.
Title: Identification of Sidt2 as a lysosomal cation-conducting protein.

SIDT2 (SID1 transmembrane family, member 2), an ortholog of the Caenorhabditis elegans putative RNA transporter SID-1 (systemic RNA interference defective-1), mediates RNA translocation during RNautophagy
Title: Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes.

SIDT2 (SID1 transmembrane family, member 2), an ortholog of the Caenorhabditis elegans putative RNA transporter SID-1 (systemic RNA interference deficient-1), mediates RNA translocation during RNautophagy.
Title: Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following SIDT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SIDT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30252	NM_001040455.2 Latest version!	Homo sapiens SID1 transmembrane family member 2 (SIDT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu30252	NM_001040455.1	Homo sapiens SID1 transmembrane family member 2 (SIDT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$587.30 $839.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SIDT2 ( NM_001040455.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035545.1 Homo sapiens SID1 transmembrane family member 2 (SIDT2), mRNA.

Price & Availability↑

CloneID	OHu30252
Clone ID Related Accession (Same CDS sequence)	NM_001040455.1 , NM_001040455.2
Accession Version	NM_001040455.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	SID1 transmembrane family member 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP005018.1 and AY358442.1. On May 17, 2019 this sequence version replaced NM_001040455.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358442.1, AK292501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000324225.9/ ENSP00000314023.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTTCGCTC TGGGCTTGCC CTTCTTGGTG CTCTTGGTGG CCTCGGTCGA GAGCCATCTG 
GGGGTTCTGG GGCCCAAGAA CGTCTCGCAG AAAGACGCCG AGTTTGAGCG CACCTACGTG 
GACGAGGTCA ACAGCGAGCT GGTCAACATC TACACCTTCA ACCATACTGT GACCCGCAAC 
AGGACAGAGG GCGTGCGTGT GTCTGTGAAC GTCCTGAACA AGCAGAAGGG GGCGCCGTTG 
CTGTTTGTGG TCCGCCAGAA GGAGGCTGTG GTGTCCTTCC AGGTGCCCCT AATCCTGCGA 
GGGATGTTTC AGCGCAAGTA CCTCTACCAA AAAGTGGAAC GAACCCTGTG TCAGCCCCCC 
ACCAAGAATG AGTCGGAGAT TCAGTTCTTC TACGTGGATG TGTCCACCCT GTCACCAGTC 
AACACCACAT ACCAGCTCCG GGTCAGCCGC ATGGACGATT TTGTGCTCAG GACTGGGGAG 
CAGTTCAGCT TCAATACCAC AGCAGCACAG CCCCAGTACT TCAAGTATGA GTTCCCTGAA 
GGCGTGGACT CGGTAATTGT CAAGGTGACC TCCAACAAGG CCTTCCCCTG CTCAGTCATC 
TCCATTCAGG ATGTGCTGTG TCCTGTCTAT GACCTGGACA ACAACGTAGC CTTCATCGGC 
ATGTACCAGA CGATGACCAA GAAGGCGGCC ATCACCGTAC AGCGCAAAGA CTTCCCCAGC 
AACAGCTTTT ATGTGGTGGT GGTGGTGAAG ACCGAAGACC AAGCCTGCGG GGGCTCCCTG 
CCTTTCTACC CCTTCGCAGA AGATGAACCG GTCGATCAAG GGCACCGCCA GAAAACCCTG 
TCAGTGCTGG TGTCTCAAGC AGTCACGTCT GAGGCATACG TCAGTGGGAT GCTCTTTTGC 
CTGGGTATAT TTCTCTCCTT TTACCTGCTG ACCGTCCTCC TGGCCTGCTG GGAGAACTGG 
AGGCAGAAGA AGAAGACCCT GCTGGTGGCC ATTGACCGAG CCTGCCCAGA AAGCGGTCAC 
CCTCGAGTCC TGGCTGATTC TTTTCCTGGC AGTTCCCCTT ATGAGGGTTA CAACTATGGC 
TCCTTTGAGA ATGTTTCTGG ATCTACCGAT GGTCTGGTTG ACAGCGCTGG CACTGGGGAC 
CTCTCTTACG GTTACCAGGG CCGCTCCTTT GAACCTGTAG GTACTCGGCC CCGAGTGGAC 
TCCATGAGCT CTGTGGAGGA GGATGACTAC GACACATTGA CCGACATCGA TTCCGACAAG 
AATGTCATTC GCACCAAGCA ATACCTCTAT GTGGCTGACC TGGCACGGAA GGACAAGCGT 
GTTCTGCGGA AAAAGTACCA GATCTACTTC TGGAACATTG CCACCATTGC TGTCTTCTAT 
GCCCTTCCTG TGGTGCAGCT GGTGATCACC TACCAGACGG TGGTGAATGT CACAGGGAAT 
CAGGACATCT GCTACTACAA CTTCCTCTGC GCCCACCCAC TGGGCAATCT CAGCGCCTTC 
AACAACATCC TCAGCAACCT GGGGTACATC CTGCTGGGGC TGCTTTTCCT GCTCATCATC 
CTGCAACGGG AGATCAACCA CAACCGGGCC CTGCTGCGCA ATGACCTCTG TGCCCTGGAA 
TGTGGGATCC CCAAACACTT TGGGCTTTTC TACGCCATGG GCACAGCCCT GATGATGGAG 
GGGCTGCTCA GTGCTTGCTA TCATGTGTGC CCCAACTATA CCAATTTCCA GTTTGACACA 
TCGTTCATGT ACATGATCGC CGGACTCTGC ATGCTGAAGC TCTACCAGAA GCGGCACCCG 
GACATCAACG CCAGCGCCTA CAGTGCCTAC GCCTGCCTGG CCATTGTCAT CTTCTTCTCT 
GTGCTGGGCG TGGTCTTTGG CAAAGGGAAC ACGGCGTTCT GGATCGTCTT CTCCATCATT 
CACATCATCG CCACCCTGCT CCTCAGCACG CAGCTCTATT ACATGGGCCG GTGGAAACTG 
GACTCGGGGA TCTTCCGCCG CATCCTCCAC GTGCTCTACA CAGACTGCAT CCGGCAGTGC 
AGCGGGCCGC TCTACGTGGA CCGCATGGTG CTGCTGGTCA TGGGCAACGT CATCAACTGG 
TCGCTGGCTG CCTATGGGCT TATCATGCGC CCCAATGATT TCGCTTCCTA CTTGTTGGCC 
ATTGGCATCT GCAACCTGCT CCTTTACTTC GCCTTCTACA TCATCATGAA GCTCCGGAGT 
GGGGAGAGGA TCAAGCTCAT CCCCCTGCTC TGCATCGTTT GCACCTCCGT GGTCTGGGGC 
TTCGCGCTCT TCTTCTTCTT CCAGGGACTC AGCACCTGGC AGAAAACCCC TGCAGAGTCG 
AGGGAGCACA ACCGGGACTG CATCCTCCTC GACTTCTTTG ACGACCACGA CATCTGGCAC 
TTCCTCTCCT CCATCGCCAT GTTCGGGTCC TTCCTGGTGT TGCTGACACT GGATGACGAC 
CTGGATACTG TGCAGCGGGA CAAGATCTAT GTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035545.1
CDS	522..3020
Translation	MFALGLPFLVLLVASVESHLGVLGPKNVSQKDAEFERTYVDEVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYFKYEFPEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQGHRQKTLSVLVSQAVTSEAYVSGMLFCLGIFLSFYLLTVLLACWENWRQKKKTLLVAIDRACPESGHPRVLADSFPGSSPYEGYNYGSFENVSGSTDGLVDSAGTGDLSYGYQGRSFEPVGTRPRVDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLYVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLCALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF

Target ORF information:

RefSeq Version	NM_001040455.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SID1 transmembrane family member 2 (SIDT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040455.2

ORF Insert Sequence:

ATGTTCGCTC TGGGCTTGCC CTTCTTGGTG CTCTTGGTGG CCTCGGTCGA GAGCCATCTG 
GGGGTTCTGG GGCCCAAGAA CGTCTCGCAG AAAGACGCCG AGTTTGAGCG CACCTACGTG 
GACGAGGTCA ACAGCGAGCT GGTCAACATC TACACCTTCA ACCATACTGT GACCCGCAAC 
AGGACAGAGG GCGTGCGTGT GTCTGTGAAC GTCCTGAACA AGCAGAAGGG GGCGCCGTTG 
CTGTTTGTGG TCCGCCAGAA GGAGGCTGTG GTGTCCTTCC AGGTGCCCCT AATCCTGCGA 
GGGATGTTTC AGCGCAAGTA CCTCTACCAA AAAGTGGAAC GAACCCTGTG TCAGCCCCCC 
ACCAAGAATG AGTCGGAGAT TCAGTTCTTC TACGTGGATG TGTCCACCCT GTCACCAGTC 
AACACCACAT ACCAGCTCCG GGTCAGCCGC ATGGACGATT TTGTGCTCAG GACTGGGGAG 
CAGTTCAGCT TCAATACCAC AGCAGCACAG CCCCAGTACT TCAAGTATGA GTTCCCTGAA 
GGCGTGGACT CGGTAATTGT CAAGGTGACC TCCAACAAGG CCTTCCCCTG CTCAGTCATC 
TCCATTCAGG ATGTGCTGTG TCCTGTCTAT GACCTGGACA ACAACGTAGC CTTCATCGGC 
ATGTACCAGA CGATGACCAA GAAGGCGGCC ATCACCGTAC AGCGCAAAGA CTTCCCCAGC 
AACAGCTTTT ATGTGGTGGT GGTGGTGAAG ACCGAAGACC AAGCCTGCGG GGGCTCCCTG 
CCTTTCTACC CCTTCGCAGA AGATGAACCG GTCGATCAAG GGCACCGCCA GAAAACCCTG 
TCAGTGCTGG TGTCTCAAGC AGTCACGTCT GAGGCATACG TCAGTGGGAT GCTCTTTTGC 
CTGGGTATAT TTCTCTCCTT TTACCTGCTG ACCGTCCTCC TGGCCTGCTG GGAGAACTGG 
AGGCAGAAGA AGAAGACCCT GCTGGTGGCC ATTGACCGAG CCTGCCCAGA AAGCGGTCAC 
CCTCGAGTCC TGGCTGATTC TTTTCCTGGC AGTTCCCCTT ATGAGGGTTA CAACTATGGC 
TCCTTTGAGA ATGTTTCTGG ATCTACCGAT GGTCTGGTTG ACAGCGCTGG CACTGGGGAC 
CTCTCTTACG GTTACCAGGG CCGCTCCTTT GAACCTGTAG GTACTCGGCC CCGAGTGGAC 
TCCATGAGCT CTGTGGAGGA GGATGACTAC GACACATTGA CCGACATCGA TTCCGACAAG 
AATGTCATTC GCACCAAGCA ATACCTCTAT GTGGCTGACC TGGCACGGAA GGACAAGCGT 
GTTCTGCGGA AAAAGTACCA GATCTACTTC TGGAACATTG CCACCATTGC TGTCTTCTAT 
GCCCTTCCTG TGGTGCAGCT GGTGATCACC TACCAGACGG TGGTGAATGT CACAGGGAAT 
CAGGACATCT GCTACTACAA CTTCCTCTGC GCCCACCCAC TGGGCAATCT CAGCGCCTTC 
AACAACATCC TCAGCAACCT GGGGTACATC CTGCTGGGGC TGCTTTTCCT GCTCATCATC 
CTGCAACGGG AGATCAACCA CAACCGGGCC CTGCTGCGCA ATGACCTCTG TGCCCTGGAA 
TGTGGGATCC CCAAACACTT TGGGCTTTTC TACGCCATGG GCACAGCCCT GATGATGGAG 
GGGCTGCTCA GTGCTTGCTA TCATGTGTGC CCCAACTATA CCAATTTCCA GTTTGACACA 
TCGTTCATGT ACATGATCGC CGGACTCTGC ATGCTGAAGC TCTACCAGAA GCGGCACCCG 
GACATCAACG CCAGCGCCTA CAGTGCCTAC GCCTGCCTGG CCATTGTCAT CTTCTTCTCT 
GTGCTGGGCG TGGTCTTTGG CAAAGGGAAC ACGGCGTTCT GGATCGTCTT CTCCATCATT 
CACATCATCG CCACCCTGCT CCTCAGCACG CAGCTCTATT ACATGGGCCG GTGGAAACTG 
GACTCGGGGA TCTTCCGCCG CATCCTCCAC GTGCTCTACA CAGACTGCAT CCGGCAGTGC 
AGCGGGCCGC TCTACGTGGA CCGCATGGTG CTGCTGGTCA TGGGCAACGT CATCAACTGG 
TCGCTGGCTG CCTATGGGCT TATCATGCGC CCCAATGATT TCGCTTCCTA CTTGTTGGCC 
ATTGGCATCT GCAACCTGCT CCTTTACTTC GCCTTCTACA TCATCATGAA GCTCCGGAGT 
GGGGAGAGGA TCAAGCTCAT CCCCCTGCTC TGCATCGTTT GCACCTCCGT GGTCTGGGGC 
TTCGCGCTCT TCTTCTTCTT CCAGGGACTC AGCACCTGGC AGAAAACCCC TGCAGAGTCG 
AGGGAGCACA ACCGGGACTG CATCCTCCTC GACTTCTTTG ACGACCACGA CATCTGGCAC 
TTCCTCTCCT CCATCGCCAT GTTCGGGTCC TTCCTGGTGT TGCTGACACT GGATGACGAC 
CTGGATACTG TGCAGCGGGA CAAGATCTAT GTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SIDT2 ( NM_001040455.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035545.1 Homo sapiens SID1 transmembrane family member 2 (SIDT2), mRNA.

Price & Availability↑

CloneID	OHu30252
Clone ID Related Accession (Same CDS sequence)	NM_001040455.1 , NM_001040455.2
Accession Version	NM_001040455.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	SID1 transmembrane family member 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY358442.1 and BX648437.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358442.1, AK292501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGTTCGCTC TGGGCTTGCC CTTCTTGGTG CTCTTGGTGG CCTCGGTCGA GAGCCATCTG 
GGGGTTCTGG GGCCCAAGAA CGTCTCGCAG AAAGACGCCG AGTTTGAGCG CACCTACGTG 
GACGAGGTCA ACAGCGAGCT GGTCAACATC TACACCTTCA ACCATACTGT GACCCGCAAC 
AGGACAGAGG GCGTGCGTGT GTCTGTGAAC GTCCTGAACA AGCAGAAGGG GGCGCCGTTG 
CTGTTTGTGG TCCGCCAGAA GGAGGCTGTG GTGTCCTTCC AGGTGCCCCT AATCCTGCGA 
GGGATGTTTC AGCGCAAGTA CCTCTACCAA AAAGTGGAAC GAACCCTGTG TCAGCCCCCC 
ACCAAGAATG AGTCGGAGAT TCAGTTCTTC TACGTGGATG TGTCCACCCT GTCACCAGTC 
AACACCACAT ACCAGCTCCG GGTCAGCCGC ATGGACGATT TTGTGCTCAG GACTGGGGAG 
CAGTTCAGCT TCAATACCAC AGCAGCACAG CCCCAGTACT TCAAGTATGA GTTCCCTGAA 
GGCGTGGACT CGGTAATTGT CAAGGTGACC TCCAACAAGG CCTTCCCCTG CTCAGTCATC 
TCCATTCAGG ATGTGCTGTG TCCTGTCTAT GACCTGGACA ACAACGTAGC CTTCATCGGC 
ATGTACCAGA CGATGACCAA GAAGGCGGCC ATCACCGTAC AGCGCAAAGA CTTCCCCAGC 
AACAGCTTTT ATGTGGTGGT GGTGGTGAAG ACCGAAGACC AAGCCTGCGG GGGCTCCCTG 
CCTTTCTACC CCTTCGCAGA AGATGAACCG GTCGATCAAG GGCACCGCCA GAAAACCCTG 
TCAGTGCTGG TGTCTCAAGC AGTCACGTCT GAGGCATACG TCAGTGGGAT GCTCTTTTGC 
CTGGGTATAT TTCTCTCCTT TTACCTGCTG ACCGTCCTCC TGGCCTGCTG GGAGAACTGG 
AGGCAGAAGA AGAAGACCCT GCTGGTGGCC ATTGACCGAG CCTGCCCAGA AAGCGGTCAC 
CCTCGAGTCC TGGCTGATTC TTTTCCTGGC AGTTCCCCTT ATGAGGGTTA CAACTATGGC 
TCCTTTGAGA ATGTTTCTGG ATCTACCGAT GGTCTGGTTG ACAGCGCTGG CACTGGGGAC 
CTCTCTTACG GTTACCAGGG CCGCTCCTTT GAACCTGTAG GTACTCGGCC CCGAGTGGAC 
TCCATGAGCT CTGTGGAGGA GGATGACTAC GACACATTGA CCGACATCGA TTCCGACAAG 
AATGTCATTC GCACCAAGCA ATACCTCTAT GTGGCTGACC TGGCACGGAA GGACAAGCGT 
GTTCTGCGGA AAAAGTACCA GATCTACTTC TGGAACATTG CCACCATTGC TGTCTTCTAT 
GCCCTTCCTG TGGTGCAGCT GGTGATCACC TACCAGACGG TGGTGAATGT CACAGGGAAT 
CAGGACATCT GCTACTACAA CTTCCTCTGC GCCCACCCAC TGGGCAATCT CAGCGCCTTC 
AACAACATCC TCAGCAACCT GGGGTACATC CTGCTGGGGC TGCTTTTCCT GCTCATCATC 
CTGCAACGGG AGATCAACCA CAACCGGGCC CTGCTGCGCA ATGACCTCTG TGCCCTGGAA 
TGTGGGATCC CCAAACACTT TGGGCTTTTC TACGCCATGG GCACAGCCCT GATGATGGAG 
GGGCTGCTCA GTGCTTGCTA TCATGTGTGC CCCAACTATA CCAATTTCCA GTTTGACACA 
TCGTTCATGT ACATGATCGC CGGACTCTGC ATGCTGAAGC TCTACCAGAA GCGGCACCCG 
GACATCAACG CCAGCGCCTA CAGTGCCTAC GCCTGCCTGG CCATTGTCAT CTTCTTCTCT 
GTGCTGGGCG TGGTCTTTGG CAAAGGGAAC ACGGCGTTCT GGATCGTCTT CTCCATCATT 
CACATCATCG CCACCCTGCT CCTCAGCACG CAGCTCTATT ACATGGGCCG GTGGAAACTG 
GACTCGGGGA TCTTCCGCCG CATCCTCCAC GTGCTCTACA CAGACTGCAT CCGGCAGTGC 
AGCGGGCCGC TCTACGTGGA CCGCATGGTG CTGCTGGTCA TGGGCAACGT CATCAACTGG 
TCGCTGGCTG CCTATGGGCT TATCATGCGC CCCAATGATT TCGCTTCCTA CTTGTTGGCC 
ATTGGCATCT GCAACCTGCT CCTTTACTTC GCCTTCTACA TCATCATGAA GCTCCGGAGT 
GGGGAGAGGA TCAAGCTCAT CCCCCTGCTC TGCATCGTTT GCACCTCCGT GGTCTGGGGC 
TTCGCGCTCT TCTTCTTCTT CCAGGGACTC AGCACCTGGC AGAAAACCCC TGCAGAGTCG 
AGGGAGCACA ACCGGGACTG CATCCTCCTC GACTTCTTTG ACGACCACGA CATCTGGCAC 
TTCCTCTCCT CCATCGCCAT GTTCGGGTCC TTCCTGGTGT TGCTGACACT GGATGACGAC 
CTGGATACTG TGCAGCGGGA CAAGATCTAT GTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035545.1
CDS	42..2540
Translation	MFALGLPFLVLLVASVESHLGVLGPKNVSQKDAEFERTYVDEVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYFKYEFPEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQGHRQKTLSVLVSQAVTSEAYVSGMLFCLGIFLSFYLLTVLLACWENWRQKKKTLLVAIDRACPESGHPRVLADSFPGSSPYEGYNYGSFENVSGSTDGLVDSAGTGDLSYGYQGRSFEPVGTRPRVDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLYVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLCALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF

Target ORF information:

RefSeq Version	NM_001040455.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SID1 transmembrane family member 2 (SIDT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040455.1

ORF Insert Sequence:

ATGTTCGCTC TGGGCTTGCC CTTCTTGGTG CTCTTGGTGG CCTCGGTCGA GAGCCATCTG 
GGGGTTCTGG GGCCCAAGAA CGTCTCGCAG AAAGACGCCG AGTTTGAGCG CACCTACGTG 
GACGAGGTCA ACAGCGAGCT GGTCAACATC TACACCTTCA ACCATACTGT GACCCGCAAC 
AGGACAGAGG GCGTGCGTGT GTCTGTGAAC GTCCTGAACA AGCAGAAGGG GGCGCCGTTG 
CTGTTTGTGG TCCGCCAGAA GGAGGCTGTG GTGTCCTTCC AGGTGCCCCT AATCCTGCGA 
GGGATGTTTC AGCGCAAGTA CCTCTACCAA AAAGTGGAAC GAACCCTGTG TCAGCCCCCC 
ACCAAGAATG AGTCGGAGAT TCAGTTCTTC TACGTGGATG TGTCCACCCT GTCACCAGTC 
AACACCACAT ACCAGCTCCG GGTCAGCCGC ATGGACGATT TTGTGCTCAG GACTGGGGAG 
CAGTTCAGCT TCAATACCAC AGCAGCACAG CCCCAGTACT TCAAGTATGA GTTCCCTGAA 
GGCGTGGACT CGGTAATTGT CAAGGTGACC TCCAACAAGG CCTTCCCCTG CTCAGTCATC 
TCCATTCAGG ATGTGCTGTG TCCTGTCTAT GACCTGGACA ACAACGTAGC CTTCATCGGC 
ATGTACCAGA CGATGACCAA GAAGGCGGCC ATCACCGTAC AGCGCAAAGA CTTCCCCAGC 
AACAGCTTTT ATGTGGTGGT GGTGGTGAAG ACCGAAGACC AAGCCTGCGG GGGCTCCCTG 
CCTTTCTACC CCTTCGCAGA AGATGAACCG GTCGATCAAG GGCACCGCCA GAAAACCCTG 
TCAGTGCTGG TGTCTCAAGC AGTCACGTCT GAGGCATACG TCAGTGGGAT GCTCTTTTGC 
CTGGGTATAT TTCTCTCCTT TTACCTGCTG ACCGTCCTCC TGGCCTGCTG GGAGAACTGG 
AGGCAGAAGA AGAAGACCCT GCTGGTGGCC ATTGACCGAG CCTGCCCAGA AAGCGGTCAC 
CCTCGAGTCC TGGCTGATTC TTTTCCTGGC AGTTCCCCTT ATGAGGGTTA CAACTATGGC 
TCCTTTGAGA ATGTTTCTGG ATCTACCGAT GGTCTGGTTG ACAGCGCTGG CACTGGGGAC 
CTCTCTTACG GTTACCAGGG CCGCTCCTTT GAACCTGTAG GTACTCGGCC CCGAGTGGAC 
TCCATGAGCT CTGTGGAGGA GGATGACTAC GACACATTGA CCGACATCGA TTCCGACAAG 
AATGTCATTC GCACCAAGCA ATACCTCTAT GTGGCTGACC TGGCACGGAA GGACAAGCGT 
GTTCTGCGGA AAAAGTACCA GATCTACTTC TGGAACATTG CCACCATTGC TGTCTTCTAT 
GCCCTTCCTG TGGTGCAGCT GGTGATCACC TACCAGACGG TGGTGAATGT CACAGGGAAT 
CAGGACATCT GCTACTACAA CTTCCTCTGC GCCCACCCAC TGGGCAATCT CAGCGCCTTC 
AACAACATCC TCAGCAACCT GGGGTACATC CTGCTGGGGC TGCTTTTCCT GCTCATCATC 
CTGCAACGGG AGATCAACCA CAACCGGGCC CTGCTGCGCA ATGACCTCTG TGCCCTGGAA 
TGTGGGATCC CCAAACACTT TGGGCTTTTC TACGCCATGG GCACAGCCCT GATGATGGAG 
GGGCTGCTCA GTGCTTGCTA TCATGTGTGC CCCAACTATA CCAATTTCCA GTTTGACACA 
TCGTTCATGT ACATGATCGC CGGACTCTGC ATGCTGAAGC TCTACCAGAA GCGGCACCCG 
GACATCAACG CCAGCGCCTA CAGTGCCTAC GCCTGCCTGG CCATTGTCAT CTTCTTCTCT 
GTGCTGGGCG TGGTCTTTGG CAAAGGGAAC ACGGCGTTCT GGATCGTCTT CTCCATCATT 
CACATCATCG CCACCCTGCT CCTCAGCACG CAGCTCTATT ACATGGGCCG GTGGAAACTG 
GACTCGGGGA TCTTCCGCCG CATCCTCCAC GTGCTCTACA CAGACTGCAT CCGGCAGTGC 
AGCGGGCCGC TCTACGTGGA CCGCATGGTG CTGCTGGTCA TGGGCAACGT CATCAACTGG 
TCGCTGGCTG CCTATGGGCT TATCATGCGC CCCAATGATT TCGCTTCCTA CTTGTTGGCC 
ATTGGCATCT GCAACCTGCT CCTTTACTTC GCCTTCTACA TCATCATGAA GCTCCGGAGT 
GGGGAGAGGA TCAAGCTCAT CCCCCTGCTC TGCATCGTTT GCACCTCCGT GGTCTGGGGC 
TTCGCGCTCT TCTTCTTCTT CCAGGGACTC AGCACCTGGC AGAAAACCCC TGCAGAGTCG 
AGGGAGCACA ACCGGGACTG CATCCTCCTC GACTTCTTTG ACGACCACGA CATCTGGCAC 
TTCCTCTCCT CCATCGCCAT GTTCGGGTCC TTCCTGGTGT TGCTGACACT GGATGACGAC 
CTGGATACTG TGCAGCGGGA CAAGATCTAT GTCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells.
RNA biology14(11)1534-1543(2017 Nov)
Takahashi M,Contu VR,Kabuta C,Hase K,Fujiwara Y,Wada K,Kabuta T

A novel family of mammalian transmembrane proteins involved in cholesterol transport.
Scientific reports7(1)7450(2017 Aug)
M?ndez-Acevedo KM,Valdes VJ,Asanov A,Vaca L

Identification of Sidt2 as a lysosomal cation-conducting protein.
FEBS letters591(1)76-87(2017 Jan)
Beck A,Fecher-Trost C,Wolske K,Philipp SE,Flockerzi V,Wissenbach U

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SIDT2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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