Gene Symbol | EXOSC1 |
Entrez Gene ID | 51013 |
Full Name | exosome component 1 |
Synonyms | CGI-108,CSL4,Csl4p,SKI4,Ski4p,p13 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]. |
Disorder MIM: |