PBX2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PBX2
Entrez Gene ID	5089
Full Name	PBX homeobox 2
Synonyms	G17,HOX12,PBX2MHC
General protein information	Preferred Names PBX homeobox 2 Names pre-B-cell leukemia transcription factor 2 XXbac-BPG300A18.13 homeobox 12 homeobox protein PBX2 pre-B-cell leukemia homeobox 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.32
Summary	This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq, Jul 2008].
Disorder MIM:	176311

mRNA and Protein(s)

mRNA	Protein	Name
NM_002586.4	NP_002577.2	pre-B-cell leukemia transcription factor 2
NM_002586.5	NP_002577.2	pre-B-cell leukemia transcription factor 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pbx2	NP_059491.1
Bos taurus (cattle)	PBX2	NP_001243812.1
Rattus norvegicus (Norway rat)	Pbx2	NP_001002828.1
Xenopus tropicalis (tropical clawed frog)	pbx2	NP_001122133.1
Homo sapiens (human)	PBX2	NP_002577.2
Pan troglodytes (chimpanzee)	PBX2	XP_001163141.1
Canis lupus familiaris (dog)	PBX2	XP_005627244.1

Gene Ontology
Bibliography

Related articles in PubMed

Variant of PBX2 gene in the 6p21.3 asthma susceptibility locus is associated with allergic rhinitis in Chinese subjects.
Zhao Y, Zhang Y, Zhang L
International forum of allergy & rhinology6(5)537-43(2016 05)

MicroRNA?1915?3p prevents the apoptosis of lung cancer cells by downregulating DRG2 and PBX2.
Xu C, Li H, Zhang L, Jia T, Duan L, Lu C
Molecular medicine reports13(1)505-12(2016 Jan)

The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway.
Errico MC, Felicetti F, Bottero L, Mattia G, Boe A, Felli N, Petrini M, Bellenghi M, Pandha HS, Calvaruso M, Tripodo C, Colombo MP, Morgan R, Car? A
International journal of cancer133(4)879-92(2013 Aug)

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Yamazaki K, Umeno J, Takahashi A, Hirano A, Johnson TA, Kumasaka N, Morizono T, Hosono N, Kawaguchi T, Takazoe M, Yamada T, Suzuki Y, Tanaka H, Motoya S, Hosokawa M, Arimura Y, Shinomura Y, Matsui T, Matsumoto T, Iida M, Tsunoda T, Nakamura Y, Kamatani N, Kubo M
Gastroenterology144(4)781-8(2013 Apr)

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Sakashita M, Yamada T, Fujieda S, Tanaka S, Doi S, Miyatake A, Enomoto T, Nishiyama C, Nakano N, Maeda K, Okumura K, Ogawa H, Ikeda S, Noguchi E, Sakamoto T, Hizawa N, Ebe K, Saeki H, Sasaki T, Ebihara T, Amagai M, Takeuchi S, Furue M, Nakamura Y, Tamari M
Nature genetics44(11)1222-6(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The findings from the present study that a SNP of the PBX2 gene in the MHC region (at 6p21.3) was associated with allergic rhinitis (AR) in allele and genotypic analysis suggests a new susceptibility gene for AR in the MHC region and another gene associated with both asthma and AR in Chinese subjects.
Title: Variant of PBX2 gene in the 6p21.3 asthma susceptibility locus is associated with allergic rhinitis in Chinese subjects.

miR19153p functions as a silencer of apoptosis, which regulates lung cancer apoptosis via targeting DRG2/PBX2.
Title: MicroRNA?1915?3p prevents the apoptosis of lung cancer cells by downregulating DRG2 and PBX2.

findings suggest the disruption of the HOXB7/PBX2 complexes, miR-221&222 inhibition or even better their combination, as innovative therapeutic approaches
Title: The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway.

a high level of PBX2 is a poor prognosticator for disease-free survival and overall survival in gingival squamous cell carcinoma
Title: Expression level of pre-B-cell leukemia transcription factor 2 (PBX2) as a prognostic marker for gingival squamous cell carcinoma.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

The following PBX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PBX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03939	NM_002586.5 Latest version!	Homo sapiens PBX homeobox 2 (PBX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu03939	NM_002586.4	Homo sapiens PBX homeobox 2 (PBX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PBX2 ( NM_002586.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002577.2 Homo sapiens PBX homeobox 2 (PBX2), mRNA.

Price & Availability↑

CloneID	OHu03939
Clone ID Related Accession (Same CDS sequence)	NM_002586.4 , NM_002586.5
Accession Version	NM_002586.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-12
Organism	Homo sapiens(human)
Product	pre-B-cell leukemia transcription factor 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X59842.1, BC082261.1, DB162975.1 and BQ182713.1. On Feb 6, 2007 this sequence version replaced NM_002586.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X59842.1, BC082261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGAAC GGCTACTGGG GCCGCCCCCT CCAGGCGGGG GCCGGGGGGG CCTGGGATTG 
GTGAGTGGGG AGCCTGGGGG CCCTGGCGAG CCTCCCGGTG GCGGAGACCC CGGTGGGGGT 
AGCGGGGGGG TCCCGGGAGG CCGAGGGAAG CAAGACATCG GGGACATTCT GCAGCAGATA 
ATGACCATCA CCGACCAGAG CCTGGACGAG GCCCAGGCCA AGAAACACGC CCTAAACTGC 
CACCGAATGA AGCCTGCTCT CTTTAGCGTC CTGTGTGAAA TCAAGGAGAA AACTGGCCTC 
AGCATTCGGA GCTCCCAGGA GGAGGAGCCG GTGGACCCAC AGCTGATGCG CTTGGACAAC 
ATGCTTCTGG CAGAGGGTGT GGCTGGGCCC GAGAAAGGGG GCGGCTCAGC AGCAGCAGCT 
GCAGCCGCTG CAGCCTCTGG TGGTGGTGTG TCCCCTGACA ACTCCATCGA ACACTCGGAC 
TATCGCAGCA AACTTGCCCA GATCCGTCAC ATATACCACT CGGAGCTGGA GAAGTATGAG 
CAGGCATGTA ATGAGTTCAC GACCCATGTC ATGAACCTGC TGAGGGAGCA GAGCCGCACC 
AGGCCCGTGG CCCCCAAAGA GATGGAACGC ATGGTGAGCA TCATCCATCG AAAGTTCAGC 
GCCATCCAGA TGCAGCTGAA GCAGAGCACC TGCGAGGCTG TGATGATCCT GCGCTCCCGT 
TTCCTGGATG CCAGACGAAA GCGCCGTAAC TTCAGCAAAC AGGCCACTGA GGTCCTAAAT 
GAGTATTTCT ACTCCCACCT GAGTAACCCA TATCCTAGTG AGGAGGCCAA GGAGGAGCTT 
GCCAAGAAGT GTGGCATCAC CGTGTCTCAG GTCTCCAACT GGTTTGGCAA CAAGAGGATT 
CGCTATAAGA AAAACATCGG AAAGTTCCAA GAGGAGGCAA ACATCTATGC TGTCAAGACC 
GCCGTGTCAG TCACCCAGGG GGGCCACAGC CGCACCAGCT CCCCGACACC CCCTTCCTCT 
GCAGGCTCTG GCGGCTCTTT CAATCTCTCA GGATCTGGAG ACATGTTTCT GGGGATGCCT 
GGGCTCAACG GAGATTCCTA TTCTGCTTCC CAGGTGGAAT CACTCCGACA CTCGATGGGG 
CCAGGGGGCT ATGGGGATAA CCTCGGGGGA GGCCAGATGT ACAGCCCACG GGAAATGAGG 
GCAAATGGCA GCTGGCAAGA GGCTGTGACC CCCTCTTCAG TGACATCCCC AACGGAGGGA 
CCAGGGAGTG TTCACTCTGA TACCTCCAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002577.2
CDS	272..1564
Translation	MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN

Target ORF information:

RefSeq Version	NM_002586.4
Organism	Homo sapiens(human)
Definition	Homo sapiens PBX homeobox 2 (PBX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002586.4

ORF Insert Sequence:

ATGGACGAAC GGCTACTGGG GCCGCCCCCT CCAGGCGGGG GCCGGGGGGG CCTGGGATTG 
GTGAGTGGGG AGCCTGGGGG CCCTGGCGAG CCTCCCGGTG GCGGAGACCC CGGTGGGGGT 
AGCGGGGGGG TCCCGGGAGG CCGAGGGAAG CAAGACATCG GGGACATTCT GCAGCAGATA 
ATGACCATCA CCGACCAGAG CCTGGACGAG GCCCAGGCCA AGAAACACGC CCTAAACTGC 
CACCGAATGA AGCCTGCTCT CTTTAGCGTC CTGTGTGAAA TCAAGGAGAA AACTGGCCTC 
AGCATTCGGA GCTCCCAGGA GGAGGAGCCG GTGGACCCAC AGCTGATGCG CTTGGACAAC 
ATGCTTCTGG CAGAGGGTGT GGCTGGGCCC GAGAAAGGGG GCGGCTCAGC AGCAGCAGCT 
GCAGCCGCTG CAGCCTCTGG TGGTGGTGTG TCCCCTGACA ACTCCATCGA ACACTCGGAC 
TATCGCAGCA AACTTGCCCA GATCCGTCAC ATATACCACT CGGAGCTGGA GAAGTATGAG 
CAGGCATGTA ATGAGTTCAC GACCCATGTC ATGAACCTGC TGAGGGAGCA GAGCCGCACC 
AGGCCCGTGG CCCCCAAAGA GATGGAACGC ATGGTGAGCA TCATCCATCG AAAGTTCAGC 
GCCATCCAGA TGCAGCTGAA GCAGAGCACC TGCGAGGCTG TGATGATCCT GCGCTCCCGT 
TTCCTGGATG CCAGACGAAA GCGCCGTAAC TTCAGCAAAC AGGCCACTGA GGTCCTAAAT 
GAGTATTTCT ACTCCCACCT GAGTAACCCA TATCCTAGTG AGGAGGCCAA GGAGGAGCTT 
GCCAAGAAGT GTGGCATCAC CGTGTCTCAG GTCTCCAACT GGTTTGGCAA CAAGAGGATT 
CGCTATAAGA AAAACATCGG AAAGTTCCAA GAGGAGGCAA ACATCTATGC TGTCAAGACC 
GCCGTGTCAG TCACCCAGGG GGGCCACAGC CGCACCAGCT CCCCGACACC CCCTTCCTCT 
GCAGGCTCTG GCGGCTCTTT CAATCTCTCA GGATCTGGAG ACATGTTTCT GGGGATGCCT 
GGGCTCAACG GAGATTCCTA TTCTGCTTCC CAGGTGGAAT CACTCCGACA CTCGATGGGG 
CCAGGGGGCT ATGGGGATAA CCTCGGGGGA GGCCAGATGT ACAGCCCACG GGAAATGAGG 
GCAAATGGCA GCTGGCAAGA GGCTGTGACC CCCTCTTCAG TGACATCCCC AACGGAGGGA 
CCAGGGAGTG TTCACTCTGA TACCTCCAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PBX2 ( NM_002586.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002577.2 Homo sapiens PBX homeobox 2 (PBX2), mRNA.

Price & Availability↑

CloneID	OHu03939
Clone ID Related Accession (Same CDS sequence)	NM_002586.4 , NM_002586.5
Accession Version	NM_002586.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	pre-B-cell leukemia transcription factor 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL662884.11, X59842.1, BC082261.1, DB162975.1 and BQ182713.1. On Nov 22, 2018 this sequence version replaced NM_002586.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X59842.1, BC082261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375050.6/ ENSP00000364190.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACGAAC GGCTACTGGG GCCGCCCCCT CCAGGCGGGG GCCGGGGGGG CCTGGGATTG 
GTGAGTGGGG AGCCTGGGGG CCCTGGCGAG CCTCCCGGTG GCGGAGACCC CGGTGGGGGT 
AGCGGGGGGG TCCCGGGAGG CCGAGGGAAG CAAGACATCG GGGACATTCT GCAGCAGATA 
ATGACCATCA CCGACCAGAG CCTGGACGAG GCCCAGGCCA AGAAACACGC CCTAAACTGC 
CACCGAATGA AGCCTGCTCT CTTTAGCGTC CTGTGTGAAA TCAAGGAGAA AACTGGCCTC 
AGCATTCGGA GCTCCCAGGA GGAGGAGCCG GTGGACCCAC AGCTGATGCG CTTGGACAAC 
ATGCTTCTGG CAGAGGGTGT GGCTGGGCCC GAGAAAGGGG GCGGCTCAGC AGCAGCAGCT 
GCAGCCGCTG CAGCCTCTGG TGGTGGTGTG TCCCCTGACA ACTCCATCGA ACACTCGGAC 
TATCGCAGCA AACTTGCCCA GATCCGTCAC ATATACCACT CGGAGCTGGA GAAGTATGAG 
CAGGCATGTA ATGAGTTCAC GACCCATGTC ATGAACCTGC TGAGGGAGCA GAGCCGCACC 
AGGCCCGTGG CCCCCAAAGA GATGGAACGC ATGGTGAGCA TCATCCATCG AAAGTTCAGC 
GCCATCCAGA TGCAGCTGAA GCAGAGCACC TGCGAGGCTG TGATGATCCT GCGCTCCCGT 
TTCCTGGATG CCAGACGAAA GCGCCGTAAC TTCAGCAAAC AGGCCACTGA GGTCCTAAAT 
GAGTATTTCT ACTCCCACCT GAGTAACCCA TATCCTAGTG AGGAGGCCAA GGAGGAGCTT 
GCCAAGAAGT GTGGCATCAC CGTGTCTCAG GTCTCCAACT GGTTTGGCAA CAAGAGGATT 
CGCTATAAGA AAAACATCGG AAAGTTCCAA GAGGAGGCAA ACATCTATGC TGTCAAGACC 
GCCGTGTCAG TCACCCAGGG GGGCCACAGC CGCACCAGCT CCCCGACACC CCCTTCCTCT 
GCAGGCTCTG GCGGCTCTTT CAATCTCTCA GGATCTGGAG ACATGTTTCT GGGGATGCCT 
GGGCTCAACG GAGATTCCTA TTCTGCTTCC CAGGTGGAAT CACTCCGACA CTCGATGGGG 
CCAGGGGGCT ATGGGGATAA CCTCGGGGGA GGCCAGATGT ACAGCCCACG GGAAATGAGG 
GCAAATGGCA GCTGGCAAGA GGCTGTGACC CCCTCTTCAG TGACATCCCC AACGGAGGGA 
CCAGGGAGTG TTCACTCTGA TACCTCCAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002577.2
CDS	288..1580
Translation	MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN

Target ORF information:

RefSeq Version	NM_002586.5
Organism	Homo sapiens(human)
Definition	Homo sapiens PBX homeobox 2 (PBX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002586.5

ORF Insert Sequence:

ATGGACGAAC GGCTACTGGG GCCGCCCCCT CCAGGCGGGG GCCGGGGGGG CCTGGGATTG 
GTGAGTGGGG AGCCTGGGGG CCCTGGCGAG CCTCCCGGTG GCGGAGACCC CGGTGGGGGT 
AGCGGGGGGG TCCCGGGAGG CCGAGGGAAG CAAGACATCG GGGACATTCT GCAGCAGATA 
ATGACCATCA CCGACCAGAG CCTGGACGAG GCCCAGGCCA AGAAACACGC CCTAAACTGC 
CACCGAATGA AGCCTGCTCT CTTTAGCGTC CTGTGTGAAA TCAAGGAGAA AACTGGCCTC 
AGCATTCGGA GCTCCCAGGA GGAGGAGCCG GTGGACCCAC AGCTGATGCG CTTGGACAAC 
ATGCTTCTGG CAGAGGGTGT GGCTGGGCCC GAGAAAGGGG GCGGCTCAGC AGCAGCAGCT 
GCAGCCGCTG CAGCCTCTGG TGGTGGTGTG TCCCCTGACA ACTCCATCGA ACACTCGGAC 
TATCGCAGCA AACTTGCCCA GATCCGTCAC ATATACCACT CGGAGCTGGA GAAGTATGAG 
CAGGCATGTA ATGAGTTCAC GACCCATGTC ATGAACCTGC TGAGGGAGCA GAGCCGCACC 
AGGCCCGTGG CCCCCAAAGA GATGGAACGC ATGGTGAGCA TCATCCATCG AAAGTTCAGC 
GCCATCCAGA TGCAGCTGAA GCAGAGCACC TGCGAGGCTG TGATGATCCT GCGCTCCCGT 
TTCCTGGATG CCAGACGAAA GCGCCGTAAC TTCAGCAAAC AGGCCACTGA GGTCCTAAAT 
GAGTATTTCT ACTCCCACCT GAGTAACCCA TATCCTAGTG AGGAGGCCAA GGAGGAGCTT 
GCCAAGAAGT GTGGCATCAC CGTGTCTCAG GTCTCCAACT GGTTTGGCAA CAAGAGGATT 
CGCTATAAGA AAAACATCGG AAAGTTCCAA GAGGAGGCAA ACATCTATGC TGTCAAGACC 
GCCGTGTCAG TCACCCAGGG GGGCCACAGC CGCACCAGCT CCCCGACACC CCCTTCCTCT 
GCAGGCTCTG GCGGCTCTTT CAATCTCTCA GGATCTGGAG ACATGTTTCT GGGGATGCCT 
GGGCTCAACG GAGATTCCTA TTCTGCTTCC CAGGTGGAAT CACTCCGACA CTCGATGGGG 
CCAGGGGGCT ATGGGGATAA CCTCGGGGGA GGCCAGATGT ACAGCCCACG GGAAATGAGG 
GCAAATGGCA GCTGGCAAGA GGCTGTGACC CCCTCTTCAG TGACATCCCC AACGGAGGGA 
CCAGGGAGTG TTCACTCTGA TACCTCCAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Variant of PBX2 gene in the 6p21.3 asthma susceptibility locus is associated with allergic rhinitis in Chinese subjects.
International forum of allergy & rhinology6(5)537-43(2016 05)
Zhao Y,Zhang Y,Zhang L

MicroRNA?1915?3p prevents the apoptosis of lung cancer cells by downregulating DRG2 and PBX2.
Molecular medicine reports13(1)505-12(2016 Jan)
Xu C,Li H,Zhang L,Jia T,Duan L,Lu C

The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway.
International journal of cancer133(4)879-92(2013 Aug)
Errico MC,Felicetti F,Bottero L,Mattia G,Boe A,Felli N,Petrini M,Bellenghi M,Pandha HS,Calvaruso M,Tripodo C,Colombo MP,Morgan R,Car? A

A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Gastroenterology144(4)781-8(2013 Apr)
Yamazaki K,Umeno J,Takahashi A,Hirano A,Johnson TA,Kumasaka N,Morizono T,Hosono N,Kawaguchi T,Takazoe M,Yamada T,Suzuki Y,Tanaka H,Motoya S,Hosokawa M,Arimura Y,Shinomura Y,Matsui T,Matsumoto T,Iida M,Tsunoda T,Nakamura Y,Kamatani N,Kubo M

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
Nature genetics44(11)1222-6(2012 Nov)
Hirota T,Takahashi A,Kubo M,Tsunoda T,Tomita K,Sakashita M,Yamada T,Fujieda S,Tanaka S,Doi S,Miyatake A,Enomoto T,Nishiyama C,Nakano N,Maeda K,Okumura K,Ogawa H,Ikeda S,Noguchi E,Sakamoto T,Hizawa N,Ebe K,Saeki H,Sasaki T,Ebihara T,Amagai M,Takeuchi S,Furue M,Nakamura Y,Tamari M

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PBX2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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