RNF141 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RNF141
Entrez Gene ID	50862
Full Name	ring finger protein 141
Synonyms	RFP141,ZFP26,ZNF230
General protein information	Preferred Names ring finger protein 141 Names RING finger protein 141 C3HC4-like zinc finger protein zinc finger protein 230
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.4\|11p15
Summary	The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis. [provided by RefSeq, Jul 2008].
Disorder MIM:	616641

mRNA and Protein(s)

mRNA	Protein	Name
NM_016422.3	NP_057506.2	RING finger protein 141
NM_016422.4	NP_057506.2	RING finger protein 141

Pathways from BioSystems

Homologies

Homo sapiens (human)	RNF141	NP_057506.2
Bos taurus (cattle)	RNF141	NP_001035656.1
Canis lupus familiaris (dog)	RNF141	NP_001041484.1
Pan troglodytes (chimpanzee)	RNF141	XP_508282.1
	RNF141	XP_001094332.2
Danio rerio (zebrafish)	rnf141	NP_001007291.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000736	XP_559376.4
Xenopus tropicalis (tropical clawed frog)	rnf141	NP_001015701.1
Gallus gallus (chicken)	RNF141	NP_001007926.1
Mus musculus (house mouse)	Rnf141	NP_080275.2
Rattus norvegicus (Norway rat)	rnf141	NP_001001800.1

Gene Ontology
Bibliography

Related articles in PubMed

The zinc finger domain of RING finger protein 141 reveals a unique RING fold.
Miyamoto K, Uechi A, Saito K
Protein science : a publication of the Protein Society26(8)1681-1686(2017 Aug)

Protein microarray characterization of the S-nitrosoproteome.
Lee YI, Giovinazzo D, Kang HC, Lee Y, Jeong JS, Doulias PT, Xie Z, Hu J, Ghasemi M, Ischiropoulos H, Qian J, Zhu H, Blackshaw S, Dawson VL, Dawson TM
Molecular & cellular proteomics : MCP13(1)63-72(2014 Jan)

High-throughput mapping of a dynamic signaling network in mammalian cells.
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL
Science (New York, N.Y.)307(5715)1621-5(2005 Mar)

Molecular cloning and characterization of a mouse spermatogenesis-related ring finger gene znf230.
Qiu W, Zhang S, Xiao C, Xu W, Ma Y, Liu Y, Wu Q
Biochemical and biophysical research communications306(2)347-53(2003 Jun)

The shorter zinc finger protein ZNF230 gene message is transcribed in fertile male testes and may be related to human spermatogenesis.
Zhang S, Qiu W, Wu H, Zhang G, Huang M, Xiao C, Yang J, Kamp C, Huang X, Huellen K, Yue Y, Pan A, Lebo R, Milunsky A, Vogt PH
The Biochemical journal359(Pt 3)721-7(2001 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A germ cell-specific transcription factor RFP141 reveals a unique RING fold.
Title: The zinc finger domain of RING finger protein 141 reveals a unique RING fold.

Analysis of the mouse counterpart.
Title: Molecular cloning and characterization of a mouse spermatogenesis-related ring finger gene znf230.

The following RNF141 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RNF141 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07150	NM_016422.4 Latest version!	Homo sapiens ring finger protein 141 (RNF141), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu07150	NM_016422.3	Homo sapiens ring finger protein 141 (RNF141), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RNF141 ( NM_016422.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057506.2 Homo sapiens ring finger protein 141 (RNF141), mRNA.

Price & Availability↑

CloneID	OHu07150
Clone ID Related Accession (Same CDS sequence)	NM_016422.3 , NM_016422.4
Accession Version	NM_016422.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-23
Organism	Homo sapiens(human)
Product	RING finger protein 141
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL598903.1, BC018104.1, BF970569.1, AL600289.1, BG108453.1, BQ229248.1, BU679024.1, CB956484.1, AI912940.1 and AI356880.1. On Oct 30, 2003 this sequence version replaced NM_016422.2. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.241925.1, SRR1803613.212919.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGACAGC AAATTTCGGA TCAGACACAG TTGGTTATTA ACAAGTTACC AGAAAAAGTA 
GCAAAACATG TTACGTTGGT TCGAGAGAGT GGCTCCTTAA CTTATGAAGA ATTTCTTGGG 
AGAGTAGCTG AGCTTAATGA TGTAACGGCT AAAGTGGCTT CTGGCCAGGA AAAACATCTT 
CTCTTTGAGG TACAACCTGG GTCTGATTCC TCTGCTTTTT GGAAAGTGGT TGTACGGGTG 
GTCTGTACCA AGATTAACAA AAGCAGTGGC ATTGTGGAGG CATCACGGAT CATGAATTTA 
TACCAGTTTA TTCAACTTTA TAAAGATATC ACAAGTCAAG CAGCAGGAGT ATTGGCACAG 
AGCTCCACCT CTGAAGAACC TGATGAAAAC TCATCCTCTG TAACATCTTG TCAGGCTAGT 
CTTTGGATGG GAAGGGTGAA GCAGCTGACC GATGAGGAGG AGTGTTGTAT CTGTATGGAT 
GGGCGGGCTG ACCTCATCCT GCCTTGTGCT CACAGCTTTT GTCAGAAGTG TATTGATAAA 
TGGAGTGATC GACACAGGAA TTGCCCTATT TGTCGCCTAC AGATGACTGG AGCAAATGAA 
TCTTGGGTGG TATCAGATGC ACCCACTGAA GATGATATGG CTAACTATAT TCTTAACATG 
GCTGATGAGG CAGGCCAGCC CCACAGGCCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057506.2
CDS	154..846
Translation	MGQQISDQTQLVINKLPEKVAKHVTLVRESGSLTYEEFLGRVAELNDVTAKVASGQEKHLLFEVQPGSDSSAFWKVVVRVVCTKINKSSGIVEASRIMNLYQFIQLYKDITSQAAGVLAQSSTSEEPDENSSSVTSCQASLWMGRVKQLTDEEECCICMDGRADLILPCAHSFCQKCIDKWSDRHRNCPICRLQMTGANESWVVSDAPTEDDMANYILNMADEAGQPHRP

Target ORF information:

RefSeq Version	NM_016422.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ring finger protein 141 (RNF141), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016422.3

ORF Insert Sequence:

ATGGGACAGC AAATTTCGGA TCAGACACAG TTGGTTATTA ACAAGTTACC AGAAAAAGTA 
GCAAAACATG TTACGTTGGT TCGAGAGAGT GGCTCCTTAA CTTATGAAGA ATTTCTTGGG 
AGAGTAGCTG AGCTTAATGA TGTAACGGCT AAAGTGGCTT CTGGCCAGGA AAAACATCTT 
CTCTTTGAGG TACAACCTGG GTCTGATTCC TCTGCTTTTT GGAAAGTGGT TGTACGGGTG 
GTCTGTACCA AGATTAACAA AAGCAGTGGC ATTGTGGAGG CATCACGGAT CATGAATTTA 
TACCAGTTTA TTCAACTTTA TAAAGATATC ACAAGTCAAG CAGCAGGAGT ATTGGCACAG 
AGCTCCACCT CTGAAGAACC TGATGAAAAC TCATCCTCTG TAACATCTTG TCAGGCTAGT 
CTTTGGATGG GAAGGGTGAA GCAGCTGACC GATGAGGAGG AGTGTTGTAT CTGTATGGAT 
GGGCGGGCTG ACCTCATCCT GCCTTGTGCT CACAGCTTTT GTCAGAAGTG TATTGATAAA 
TGGAGTGATC GACACAGGAA TTGCCCTATT TGTCGCCTAC AGATGACTGG AGCAAATGAA 
TCTTGGGTGG TATCAGATGC ACCCACTGAA GATGATATGG CTAACTATAT TCTTAACATG 
GCTGATGAGG CAGGCCAGCC CCACAGGCCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RNF141 ( NM_016422.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057506.2 Homo sapiens ring finger protein 141 (RNF141), mRNA.

Price & Availability↑

CloneID	OHu07150
Clone ID Related Accession (Same CDS sequence)	NM_016422.3 , NM_016422.4
Accession Version	NM_016422.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	RING finger protein 141
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL598903.1, BC018104.1, BF970569.1, AL600289.1, BG108453.1, BQ229248.1, BU679024.1, CB956484.1, AI912940.1, AI356880.1 and AC021914.7. On Nov 22, 2018 this sequence version replaced NM_016422.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.60761.1, SRR1660809.49586.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265981.7/ ENSP00000265981.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGACAGC AAATTTCGGA TCAGACACAG TTGGTTATTA ACAAGTTACC AGAAAAAGTA 
GCAAAACATG TTACGTTGGT TCGAGAGAGT GGCTCCTTAA CTTATGAAGA ATTTCTTGGG 
AGAGTAGCTG AGCTTAATGA TGTAACGGCT AAAGTGGCTT CTGGCCAGGA AAAACATCTT 
CTCTTTGAGG TACAACCTGG GTCTGATTCC TCTGCTTTTT GGAAAGTGGT TGTACGGGTG 
GTCTGTACCA AGATTAACAA AAGCAGTGGC ATTGTGGAGG CATCACGGAT CATGAATTTA 
TACCAGTTTA TTCAACTTTA TAAAGATATC ACAAGTCAAG CAGCAGGAGT ATTGGCACAG 
AGCTCCACCT CTGAAGAACC TGATGAAAAC TCATCCTCTG TAACATCTTG TCAGGCTAGT 
CTTTGGATGG GAAGGGTGAA GCAGCTGACC GATGAGGAGG AGTGTTGTAT CTGTATGGAT 
GGGCGGGCTG ACCTCATCCT GCCTTGTGCT CACAGCTTTT GTCAGAAGTG TATTGATAAA 
TGGAGTGATC GACACAGGAA TTGCCCTATT TGTCGCCTAC AGATGACTGG AGCAAATGAA 
TCTTGGGTGG TATCAGATGC ACCCACTGAA GATGATATGG CTAACTATAT TCTTAACATG 
GCTGATGAGG CAGGCCAGCC CCACAGGCCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057506.2
CDS	114..806
Translation	MGQQISDQTQLVINKLPEKVAKHVTLVRESGSLTYEEFLGRVAELNDVTAKVASGQEKHLLFEVQPGSDSSAFWKVVVRVVCTKINKSSGIVEASRIMNLYQFIQLYKDITSQAAGVLAQSSTSEEPDENSSSVTSCQASLWMGRVKQLTDEEECCICMDGRADLILPCAHSFCQKCIDKWSDRHRNCPICRLQMTGANESWVVSDAPTEDDMANYILNMADEAGQPHRP

Target ORF information:

RefSeq Version	NM_016422.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ring finger protein 141 (RNF141), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016422.4

ORF Insert Sequence:

ATGGGACAGC AAATTTCGGA TCAGACACAG TTGGTTATTA ACAAGTTACC AGAAAAAGTA 
GCAAAACATG TTACGTTGGT TCGAGAGAGT GGCTCCTTAA CTTATGAAGA ATTTCTTGGG 
AGAGTAGCTG AGCTTAATGA TGTAACGGCT AAAGTGGCTT CTGGCCAGGA AAAACATCTT 
CTCTTTGAGG TACAACCTGG GTCTGATTCC TCTGCTTTTT GGAAAGTGGT TGTACGGGTG 
GTCTGTACCA AGATTAACAA AAGCAGTGGC ATTGTGGAGG CATCACGGAT CATGAATTTA 
TACCAGTTTA TTCAACTTTA TAAAGATATC ACAAGTCAAG CAGCAGGAGT ATTGGCACAG 
AGCTCCACCT CTGAAGAACC TGATGAAAAC TCATCCTCTG TAACATCTTG TCAGGCTAGT 
CTTTGGATGG GAAGGGTGAA GCAGCTGACC GATGAGGAGG AGTGTTGTAT CTGTATGGAT 
GGGCGGGCTG ACCTCATCCT GCCTTGTGCT CACAGCTTTT GTCAGAAGTG TATTGATAAA 
TGGAGTGATC GACACAGGAA TTGCCCTATT TGTCGCCTAC AGATGACTGG AGCAAATGAA 
TCTTGGGTGG TATCAGATGC ACCCACTGAA GATGATATGG CTAACTATAT TCTTAACATG 
GCTGATGAGG CAGGCCAGCC CCACAGGCCA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The zinc finger domain of RING finger protein 141 reveals a unique RING fold.
Protein science : a publication of the Protein Society26(8)1681-1686(2017 Aug)
Miyamoto K,Uechi A,Saito K

Protein microarray characterization of the S-nitrosoproteome.
Molecular & cellular proteomics : MCP13(1)63-72(2014 Jan)
Lee YI,Giovinazzo D,Kang HC,Lee Y,Jeong JS,Doulias PT,Xie Z,Hu J,Ghasemi M,Ischiropoulos H,Qian J,Zhu H,Blackshaw S,Dawson VL,Dawson TM

High-throughput mapping of a dynamic signaling network in mammalian cells.
Science (New York, N.Y.)307(5715)1621-5(2005 Mar)
Barrios-Rodiles M,Brown KR,Ozdamar B,Bose R,Liu Z,Donovan RS,Shinjo F,Liu Y,Dembowy J,Taylor IW,Luga V,Przulj N,Robinson M,Suzuki H,Hayashizaki Y,Jurisica I,Wrana JL

Molecular cloning and characterization of a mouse spermatogenesis-related ring finger gene znf230.
Biochemical and biophysical research communications306(2)347-53(2003 Jun)
Qiu W,Zhang S,Xiao C,Xu W,Ma Y,Liu Y,Wu Q

The shorter zinc finger protein ZNF230 gene message is transcribed in fertile male testes and may be related to human spermatogenesis.
The Biochemical journal359(Pt 3)721-7(2001 Nov)
Zhang S,Qiu W,Wu H,Zhang G,Huang M,Xiao C,Yang J,Kamp C,Huang X,Huellen K,Yue Y,Pan A,Lebo R,Milunsky A,Vogt PH

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RNF141 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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