TAS2R9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS2R9
Entrez Gene ID	50835
Full Name	taste 2 receptor member 9
Synonyms	T2R9,TRB6
General protein information	Preferred Names taste 2 receptor member 9 Names taste receptor type 2 member 9 taste receptor, family B, member 6 taste receptor, type 2, member 9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.2
Summary	This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008].
Disorder MIM:	604795

mRNA and Protein(s)

mRNA	Protein	Name
NM_023917.2	NP_076406.1	taste receptor type 2 member 9

Pathways from BioSystems

Homologies

	LOC717940	XP_001115467.1
Xenopus tropicalis (tropical clawed frog)	tas2r7	NP_001165465.1
Homo sapiens (human)	TAS2R9	NP_076406.1
Canis lupus familiaris (dog)	TAS2R9	XP_003640026.1
Xenopus tropicalis (tropical clawed frog)	t2r10	NP_001165473.1
Pan troglodytes (chimpanzee)	TAS2R9	XP_001150212.1
Xenopus tropicalis (tropical clawed frog)	t2r2	NP_001165409.1

Gene Ontology
Bibliography

Related articles in PubMed

Differences in food intake and genetic variability in taste receptors between Czech pregnant women with and without gestational diabetes mellitus.
Bart?kov? V, Kuricov? K, Zl?mal F, B?lobr?dkov? J, Ka?kov? K
European journal of nutrition(2016 Oct)

Bitter taste receptors influence glucose homeostasis.
Dotson CD, Zhang L, Xu H, Shin YK, Vigues S, Ott SH, Elson AE, Choi HJ, Shaw H, Egan JM, Mitchell BD, Li X, Steinle NI, Munger SD
PloS one3(12)e3974(2008)

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Go Y, Satta Y, Takenaka O, Takahata N
Genetics170(1)313-26(2005 May)

Evolution of bitter taste receptors in humans and apes.
Fischer A, Gilad Y, Man O, P??bo S
Molecular biology and evolution22(3)432-6(2005 Mar)

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ
Cell112(3)293-301(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A functionally compromised TAS2R receptor negatively impacts glucose homeostasis, providing an important link between alimentary chemosensation and metabolic disease.
Title: Bitter taste receptors influence glucose homeostasis.

The following TAS2R9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS2R9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29843	NM_023917.2 Latest version!	Homo sapiens taste 2 receptor member 9 (TAS2R9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS2R9 ( NM_023917.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_076406.1 Homo sapiens taste 2 receptor member 9 (TAS2R9), mRNA.

Price & Availability↑

CloneID	OHu29843
Clone ID Related Accession (Same CDS sequence)	NM_023917.2
Accession Version	NM_023917.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 9
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC095519.1 and BC069066.1. On Jun 23, 2005 this sequence version replaced NM_023917.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC095519.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000240691.4/ ENSP00000240691.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCCAAGTG CAATAGAGGC AATATATATT ATTTTAATTG CTGGTGAATT GACCATAGGG 
ATTTGGGGAA ATGGATTCAT TGTACTAGTT AACTGCATTG ACTGGCTCAA AAGAAGAGAT 
ATTTCCTTGA TTGACATCAT CCTGATCAGC TTGGCCATCT CCAGAATCTG TCTGCTGTGT 
GTAATATCAT TAGATGGCTT CTTTATGCTG CTCTTTCCAG GTACATATGG CAATAGCGTG 
CTAGTAAGCA TTGTGAATGT TGTCTGGACA TTTGCCAATA ATTCAAGTCT CTGGTTTACT 
TCTTGCCTCA GTATCTTCTA TTTACTCAAG ATAGCCAATA TATCGCACCC ATTTTTCTTC 
TGGCTGAAGC TAAAGATCAA CAAGGTCATG CTTGCGATTC TTCTGGGGTC CTTTCTTATC 
TCTTTAATTA TTAGTGTTCC AAAGAATGAT GATATGTGGT ATCACCTTTT CAAAGTCAGT 
CATGAAGAAA ACATTACTTG GAAATTCAAA GTGAGTAAAA TTCCAGGTAC TTTCAAACAG 
TTAACCCTGA ACCTGGGGGT GATGGTTCCC TTTATCCTTT GCCTGATCTC ATTTTTCTTG 
TTACTTTTCT CCCTAGTTAG ACACACCAAG CAGATTCGAC TGCATGCTAC AGGGTTCAGA 
GACCCCAGTA CAGAGGCCCA CATGAGGGCC ATAAAGGCAG TGATCATCTT TCTGCTCCTC 
CTCATCGTGT ACTACCCAGT CTTTCTTGTT ATGACCTCTA GCGCTCTGAT TCCTCAGGGA 
AAATTAGTGT TGATGATTGG TGACATAGTA ACTGTCATTT TCCCATCAAG CCATTCATTC 
ATTCTAATTA TGGGAAATAG CAAGTTGAGG GAAGCTTTTC TGAAGATGTT AAGATTTGTG 
AAGTGTTTCC TTAGAAGAAG AAAGCCTTTT GTTCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076406.1
CDS	94..1032
Translation	MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVKCFLRRRKPFVP

Target ORF information:

RefSeq Version	NM_023917.2
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 9 (TAS2R9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023917.2

ORF Insert Sequence:

ATGCCAAGTG CAATAGAGGC AATATATATT ATTTTAATTG CTGGTGAATT GACCATAGGG 
ATTTGGGGAA ATGGATTCAT TGTACTAGTT AACTGCATTG ACTGGCTCAA AAGAAGAGAT 
ATTTCCTTGA TTGACATCAT CCTGATCAGC TTGGCCATCT CCAGAATCTG TCTGCTGTGT 
GTAATATCAT TAGATGGCTT CTTTATGCTG CTCTTTCCAG GTACATATGG CAATAGCGTG 
CTAGTAAGCA TTGTGAATGT TGTCTGGACA TTTGCCAATA ATTCAAGTCT CTGGTTTACT 
TCTTGCCTCA GTATCTTCTA TTTACTCAAG ATAGCCAATA TATCGCACCC ATTTTTCTTC 
TGGCTGAAGC TAAAGATCAA CAAGGTCATG CTTGCGATTC TTCTGGGGTC CTTTCTTATC 
TCTTTAATTA TTAGTGTTCC AAAGAATGAT GATATGTGGT ATCACCTTTT CAAAGTCAGT 
CATGAAGAAA ACATTACTTG GAAATTCAAA GTGAGTAAAA TTCCAGGTAC TTTCAAACAG 
TTAACCCTGA ACCTGGGGGT GATGGTTCCC TTTATCCTTT GCCTGATCTC ATTTTTCTTG 
TTACTTTTCT CCCTAGTTAG ACACACCAAG CAGATTCGAC TGCATGCTAC AGGGTTCAGA 
GACCCCAGTA CAGAGGCCCA CATGAGGGCC ATAAAGGCAG TGATCATCTT TCTGCTCCTC 
CTCATCGTGT ACTACCCAGT CTTTCTTGTT ATGACCTCTA GCGCTCTGAT TCCTCAGGGA 
AAATTAGTGT TGATGATTGG TGACATAGTA ACTGTCATTT TCCCATCAAG CCATTCATTC 
ATTCTAATTA TGGGAAATAG CAAGTTGAGG GAAGCTTTTC TGAAGATGTT AAGATTTGTG 
AAGTGTTTCC TTAGAAGAAG AAAGCCTTTT GTTCCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Differences in food intake and genetic variability in taste receptors between Czech pregnant women with and without gestational diabetes mellitus.
European journal of nutrition(2016 Oct)
Bart?kov? V,Kuricov? K,Zl?mal F,B?lobr?dkov? J,Ka?kov? K

Bitter taste receptors influence glucose homeostasis.
PloS one3(12)e3974(2008)
Dotson CD,Zhang L,Xu H,Shin YK,Vigues S,Ott SH,Elson AE,Choi HJ,Shaw H,Egan JM,Mitchell BD,Li X,Steinle NI,Munger SD

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics170(1)313-26(2005 May)
Go Y,Satta Y,Takenaka O,Takahata N

Evolution of bitter taste receptors in humans and apes.
Molecular biology and evolution22(3)432-6(2005 Mar)
Fischer A,Gilad Y,Man O,P??bo S

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.
Cell112(3)293-301(2003 Feb)
Zhang Y,Hoon MA,Chandrashekar J,Mueller KL,Cook B,Wu D,Zuker CS,Ryba NJ

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TAS2R9 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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