PAFAH1B3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PAFAH1B3
Entrez Gene ID	5050
Full Name	platelet activating factor acetylhydrolase 1b catalytic subunit 3
Synonyms	PAFAHG
General protein information	Preferred Names platelet activating factor acetylhydrolase 1b catalytic subunit 3 Names platelet-activating factor acetylhydrolase IB subunit gamma PAF acetylhydrolase 29 kDa subunit PAF-AH 29 kDa subunit PAF-AH subunit gamma PAF-AH1b alpha 1 subunit PAFAH subunit gamma platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) platelet-activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009].
Disorder MIM:	603074

mRNA and Protein(s)

mRNA	Protein	Name
XM_017026848.1	XP_016882337.1	platelet-activating factor acetylhydrolase IB subunit gamma isoform X1
NM_002573.3	NP_002564.1	platelet-activating factor acetylhydrolase IB subunit gamma
NM_001145939.1	NP_001139411.1	platelet-activating factor acetylhydrolase IB subunit gamma
NM_001145940.1	NP_001139412.1	platelet-activating factor acetylhydrolase IB subunit gamma
XM_017026846.1	XP_016882335.1	platelet-activating factor acetylhydrolase IB subunit gamma isoform X1
XM_017026847.1	XP_016882336.1	platelet-activating factor acetylhydrolase IB subunit gamma isoform X1
NM_002573.4	NP_002564.1	platelet-activating factor acetylhydrolase IB subunit gamma

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Pafah1b3	NP_032802.1
Danio rerio (zebrafish)	pafah1b3	NP_957352.1
Pan troglodytes (chimpanzee)	PAFAH1B3	XP_003953557.1
	PAFAH1B3	XP_002801307.1
Bos taurus (cattle)	PAFAH1B3	NP_777090.1
Xenopus tropicalis (tropical clawed frog)	pafah1b3	NP_001006715.1
Canis lupus familiaris (dog)	PAFAH1B3	XP_005616589.1
Rattus norvegicus (Norway rat)	Pafah1b3	NP_446106.1
Homo sapiens (human)	PAFAH1B3	NP_002564.1

Gene Ontology
Bibliography

Related articles in PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer.
Kohnz RA, Mulvihill MM, Chang JW, Hsu KL, Sorrentino A, Cravatt BF, Bandyopadhyay S, Goga A, Nomura DK
ACS chemical biology10(7)1624-30(2015 Jul)

Metabolic profiling reveals PAFAH1B3 as a critical driver of breast cancer pathogenicity.
Mulvihill MM, Benjamin DI, Ji X, Le Scolan E, Louie SM, Shieh A, Green M, Narasimhalu T, Morris PJ, Luo K, Nomura DK
Chemistry & biology21(7)831-40(2014 Jul)

FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.
Teh MT, Gemenetzidis E, Patel D, Tariq R, Nadir A, Bahta AW, Waseem A, Hutchison IL
PloS one7(3)e34329(2012)

Opposing effects of Ndel1 and alpha1 or alpha2 on cytoplasmic dynein through competitive binding to Lis1.
Ding C, Liang X, Ma L, Yuan X, Zhu X
Journal of cell science122(Pt 16)2820-7(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PAFAH1B2 and 1B3 are important in maintaining cancer pathogenicity across a wide spectrum of cancer types.
Title: Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer.

PAFAH1B3 as a critical metabolic node in breast cancer
Title: Metabolic profiling reveals PAFAH1B3 as a critical driver of breast cancer pathogenicity.

PAFAH1B3 has been found to be differentially methylated in head and neck squamous cell carcinoma.
Title: FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.

intracellular type I PAF acetylhydrolase (PAFAH1B2 and PAFAH1B3) is the major aspirin hydrolase of human blood
Title: Intracellular erythrocyte platelet-activating factor acetylhydrolase I inactivates aspirin in blood.

These results indicate an antagonistic effect of alpha1, alpha2 and Ndel1 for Lis1 binding, probably to modulate dynein functions in vivo.
Title: Opposing effects of Ndel1 and alpha1 or alpha2 on cytoplasmic dynein through competitive binding to Lis1.

The following PAFAH1B3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAFAH1B3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02878	NM_002573.4 Latest version!	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02878	NM_001145940.1 Latest version!	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu02878	NM_001145939.1 Latest version!	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu88495	XM_017026848.1 Latest version!	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu88495	XM_017026847.1 Latest version!	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu88495	XM_017026846.1 Latest version!	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu02878	NM_002573.3	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PAFAH1B3 ( NM_002573.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002564.1 Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02878
Clone ID Related Accession (Same CDS sequence)	NM_002573.3 , NM_001145939.1 , NM_001145940.1 , NM_002573.4
Accession Version	NM_002573.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	platelet-activating factor acetylhydrolase IB subunit gamma
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB216829.1 and BC003016.1. On Mar 21, 2009 this sequence version replaced NM_002573.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003016.1, SRR1163658.299038.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002564.1
CDS	336..1031
Translation	MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP

Target ORF information:

RefSeq Version	NM_002573.3
Organism	Homo sapiens(human)
Definition	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002573.3

ORF Insert Sequence:

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAFAH1B3 ( NM_001145939.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139411.1 Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02878
Clone ID Related Accession (Same CDS sequence)	NM_002573.3 , NM_001145939.1 , NM_001145940.1 , NM_002573.4
Accession Version	NM_001145939.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	platelet-activating factor acetylhydrolase IB subunit gamma
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE048307.1 and BC003016.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.548635.1, SRR1163657.335438.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139411.1
CDS	358..1053
Translation	MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP

Target ORF information:

RefSeq Version	NM_001145939.1
Organism	Homo sapiens(human)
Definition	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145939.1

ORF Insert Sequence:

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAFAH1B3 ( NM_001145940.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139412.1 Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu02878
Clone ID Related Accession (Same CDS sequence)	NM_002573.3 , NM_001145939.1 , NM_001145940.1 , NM_002573.4
Accession Version	NM_001145940.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	platelet-activating factor acetylhydrolase IB subunit gamma
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA432316.1 and BC003016.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF058315.1, BP261876.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139412.1
CDS	119..814
Translation	MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP

Target ORF information:

RefSeq Version	NM_001145940.1
Organism	Homo sapiens(human)
Definition	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145940.1

ORF Insert Sequence:

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAFAH1B3 ( NM_002573.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002564.1 Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02878
Clone ID Related Accession (Same CDS sequence)	NM_002573.3 , NM_001145939.1 , NM_001145940.1 , NM_002573.4
Accession Version	NM_002573.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	platelet-activating factor acetylhydrolase IB subunit gamma
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB216829.1 and BC003016.1. On Jun 2, 2019 this sequence version replaced NM_002573.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.561806.1, SRR1163657.8512.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002564.1
CDS	316..1011
Translation	MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP

Target ORF information:

RefSeq Version	NM_002573.4
Organism	Homo sapiens(human)
Definition	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002573.4

ORF Insert Sequence:

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG TGAATGAGCG ACAGCCCCAG GCCCGGGTTG TGGTGCTGGG CCTGCTTCCG 
CGAGGCCAAC ATCCCAACCC ACTTCGGGAG AAGAACCGAC AGGTGAACGA GCTGGTACGG 
GCGGCACTGG CTGGCCACCC TCGGGCCCAC TTCCTAGATG CCGACCCTGG CTTTGTGCAC 
TCAGATGGCA CCATCAGCCA TCATGACATG TATGATTACC TGCATCTGAG CCGCCTGGGC 
TACACACCTG TTTGCCGGGC TCTGCACTCC CTGCTTCTGC GTCTGCTGGC CCAAGACCAG 
GGCCAAGGTG CTCCCCTGCT GGAGCCCGCA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAFAH1B3 ( XM_017026848.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882337.1 Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu88495
Clone ID Related Accession (Same CDS sequence)	XM_017026848.1 , XM_017026846.1 , XM_017026847.1
Accession Version	XM_017026848.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	platelet-activating factor acetylhydrolase IB subunit gamma isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG GCCTGCTTCC GCGAGGCCAA CATCCCAACC CACTTCGGGA GAAGAACCGA 
CAGGTGAACG AGCTGGTACG GGCGGCACTG GCTGGCCACC CTCGGGCCCA CTTCCTAGAT 
GCCGACCCTG GCTTTGTGCA CTCAGATGGC ACCATCAGCC ATCATGACAT GTATGATTAC 
CTGCATCTGA GCCGCCTGGG CTACACACCT GTTTGCCGGG CTCTGCACTC CCTGCTTCTG 
CGTCTGCTGG CCCAAGACCA GGGCCAAGGT GCTCCCCTGC TGGAGCCCGC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882337.1
CDS	119..775
Translation	MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP

Target ORF information:

RefSeq Version	XM_017026848.1
Organism	Homo sapiens(human)
Definition	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026848.1

ORF Insert Sequence:

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG GCCTGCTTCC GCGAGGCCAA CATCCCAACC CACTTCGGGA GAAGAACCGA 
CAGGTGAACG AGCTGGTACG GGCGGCACTG GCTGGCCACC CTCGGGCCCA CTTCCTAGAT 
GCCGACCCTG GCTTTGTGCA CTCAGATGGC ACCATCAGCC ATCATGACAT GTATGATTAC 
CTGCATCTGA GCCGCCTGGG CTACACACCT GTTTGCCGGG CTCTGCACTC CCTGCTTCTG 
CGTCTGCTGG CCCAAGACCA GGGCCAAGGT GCTCCCCTGC TGGAGCCCGC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAFAH1B3 ( XM_017026846.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882335.1 Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88495
Clone ID Related Accession (Same CDS sequence)	XM_017026848.1 , XM_017026846.1 , XM_017026847.1
Accession Version	XM_017026846.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	platelet-activating factor acetylhydrolase IB subunit gamma isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG GCCTGCTTCC GCGAGGCCAA CATCCCAACC CACTTCGGGA GAAGAACCGA 
CAGGTGAACG AGCTGGTACG GGCGGCACTG GCTGGCCACC CTCGGGCCCA CTTCCTAGAT 
GCCGACCCTG GCTTTGTGCA CTCAGATGGC ACCATCAGCC ATCATGACAT GTATGATTAC 
CTGCATCTGA GCCGCCTGGG CTACACACCT GTTTGCCGGG CTCTGCACTC CCTGCTTCTG 
CGTCTGCTGG CCCAAGACCA GGGCCAAGGT GCTCCCCTGC TGGAGCCCGC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882335.1
CDS	188..844
Translation	MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP

Target ORF information:

RefSeq Version	XM_017026846.1
Organism	Homo sapiens(human)
Definition	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026846.1

ORF Insert Sequence:

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG GCCTGCTTCC GCGAGGCCAA CATCCCAACC CACTTCGGGA GAAGAACCGA 
CAGGTGAACG AGCTGGTACG GGCGGCACTG GCTGGCCACC CTCGGGCCCA CTTCCTAGAT 
GCCGACCCTG GCTTTGTGCA CTCAGATGGC ACCATCAGCC ATCATGACAT GTATGATTAC 
CTGCATCTGA GCCGCCTGGG CTACACACCT GTTTGCCGGG CTCTGCACTC CCTGCTTCTG 
CGTCTGCTGG CCCAAGACCA GGGCCAAGGT GCTCCCCTGC TGGAGCCCGC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAFAH1B3 ( XM_017026847.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882336.1 Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu88495
Clone ID Related Accession (Same CDS sequence)	XM_017026848.1 , XM_017026846.1 , XM_017026847.1
Accession Version	XM_017026847.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	platelet-activating factor acetylhydrolase IB subunit gamma isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG GCCTGCTTCC GCGAGGCCAA CATCCCAACC CACTTCGGGA GAAGAACCGA 
CAGGTGAACG AGCTGGTACG GGCGGCACTG GCTGGCCACC CTCGGGCCCA CTTCCTAGAT 
GCCGACCCTG GCTTTGTGCA CTCAGATGGC ACCATCAGCC ATCATGACAT GTATGATTAC 
CTGCATCTGA GCCGCCTGGG CTACACACCT GTTTGCCGGG CTCTGCACTC CCTGCTTCTG 
CGTCTGCTGG CCCAAGACCA GGGCCAAGGT GCTCCCCTGC TGGAGCCCGC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882336.1
CDS	353..1009
Translation	MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP

Target ORF information:

RefSeq Version	XM_017026847.1
Organism	Homo sapiens(human)
Definition	Homo sapiens platelet activating factor acetylhydrolase 1b catalytic subunit 3 (PAFAH1B3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026847.1

ORF Insert Sequence:

ATGAGTGGAG AGGAGAACCC AGCCAGCAAG CCCACGCCGG TGCAGGACGT ACAGGGCGAC 
GGGCGCTGGA TGTCCCTGCA CCATCGGTTC GTGGCTGACA GCAAAGATAA GGAACCCGAA 
GTCGTCTTCA TCGGGGACTC CTTGGTCCAG CTCATGCACC AGTGCGAGAT CTGGCGCGAG 
CTCTTCTCTC CTCTGCATGC ACTTAACTTT GGCATTGGTG GTGACGGCAC ACAGCATGTA 
CTGTGGCGGC TGGAGAATGG GGAGCTGGAA CACATCCGGC CCAAGATTGT GGTGGTCTGG 
GTGGGCACCA ACAACCACGG ACACACAGCA GAGCAGGTGA CTGGTGGCAT CAAGGCCATT 
GTGCAACTGG GCCTGCTTCC GCGAGGCCAA CATCCCAACC CACTTCGGGA GAAGAACCGA 
CAGGTGAACG AGCTGGTACG GGCGGCACTG GCTGGCCACC CTCGGGCCCA CTTCCTAGAT 
GCCGACCCTG GCTTTGTGCA CTCAGATGGC ACCATCAGCC ATCATGACAT GTATGATTAC 
CTGCATCTGA GCCGCCTGGG CTACACACCT GTTTGCCGGG CTCTGCACTC CCTGCTTCTG 
CGTCTGCTGG CCCAAGACCA GGGCCAAGGT GCTCCCCTGC TGGAGCCCGC ACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer.
ACS chemical biology10(7)1624-30(2015 Jul)
Kohnz RA,Mulvihill MM,Chang JW,Hsu KL,Sorrentino A,Cravatt BF,Bandyopadhyay S,Goga A,Nomura DK

Metabolic profiling reveals PAFAH1B3 as a critical driver of breast cancer pathogenicity.
Chemistry & biology21(7)831-40(2014 Jul)
Mulvihill MM,Benjamin DI,Ji X,Le Scolan E,Louie SM,Shieh A,Green M,Narasimhalu T,Morris PJ,Luo K,Nomura DK

FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.
PloS one7(3)e34329(2012)
Teh MT,Gemenetzidis E,Patel D,Tariq R,Nadir A,Bahta AW,Waseem A,Hutchison IL

Opposing effects of Ndel1 and alpha1 or alpha2 on cytoplasmic dynein through competitive binding to Lis1.
Journal of cell science122(Pt 16)2820-7(2009 Aug)
Ding C,Liang X,Ma L,Yuan X,Zhu X

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PAFAH1B3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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