DUXA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DUXA
Entrez Gene ID	503835
Full Name	double homeobox A
General protein information	Preferred Names double homeobox A Names double homeobox protein A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.43
Summary	Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the DUXA homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008].
Disorder MIM:	611168

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012729.1	NP_001012747.1	double homeobox protein A
NM_001012729.2	NP_001012747.1	double homeobox protein A

Pathways from BioSystems

Homologies

Homo sapiens (human)	DUXA	NP_001012747.1
Bos taurus (cattle)	DUXA	XP_005219865.1
Pan troglodytes (chimpanzee)	DUXA	XP_524417.2
	LOC709447	XP_001097965.2

Gene Ontology
Bibliography

Related articles in PubMed

Wnt signaling and Dupuytren's disease.
Dolmans GH, Werker PM, Hennies HC, Furniss D, Festen EA, Franke L, Becker K, van der Vlies P, Wolffenbuttel BH, Tinschert S, Toliat MR, Nothnagel M, Franke A, Klopp N, Wichmann HE, N?rnberg P, Giele H, Ophoff RA, Wijmenga C, , , ,
The New England journal of medicine365(4)307-17(2011 Jul)

Annotation, nomenclature and evolution of four novel homeobox genes expressed in the human germ line.
Booth HA, Holland PW
Gene387(1-2)7-14(2007 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DUXA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DUXA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04077	NM_001012729.2 Latest version!	Homo sapiens double homeobox A (DUXA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
View Old Accession Versions >>
OHu04077	NM_001012729.1	Homo sapiens double homeobox A (DUXA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DUXA ( NM_001012729.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001012747.1 Homo sapiens double homeobox A (DUXA), mRNA.

Price & Availability↑

CloneID	OHu04077
Clone ID Related Accession (Same CDS sequence)	NM_001012729.1 , NM_001012729.2
Accession Version	NM_001012729.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 615bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	double homeobox protein A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. This record has been curated by NCBI staff in collaboration with Anne Booth and Peter Holland. The reference sequence was derived from AC025588.1. ##Evidence-Data-START## Transcript exon combination :: LN651089.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGAAG ACACCTATTC ACACAAGATG GTAAAAACAA ATCATAGGCG CTGTCGCACA 
AAATTCACAG AAGAACAGTT GAAAATCCTC ATCAATACCT TCAATCAAAA GCCTTACCCA 
GGTTATGCTA CCAAACAAAA ACTTGCTTTA GAAATCAATA CAGAAGAGTC CAGAATCCAG 
ATTTGGTTTC AGAATCGAAG AGCTAGGCAC GGATTCCAGA AAAGACCAGA AGCTGAGACT 
TTAGAATCAA GCCAGAGCCA GGGGCAAGAT CAACCTGGTG TGGAGTTTCA AAGTAGAGAA 
GCCAGACGGT GTCGTACCAC CTACAGCGCC TCTCAGTTAC ACACTCTCAT CAAGGCATTT 
ATGAAAAACC CATATCCTGG GATTGATTCC AGAGAAGAAC TTGCTAAAGA AATCGGTGTT 
CCAGAGTCAA GAGTCCAAAT TTGGTTCCAA AATCGAAGAT CTAGATTACT TCTCCAGAGA 
AAAAGGGAAC CTGTGGCGTC CTTAGAACAA GAAGAGCAGG GCAAGATTCC TGAGGGACTG 
CAAGGTGCAG AAGATACACA AAATGGCACC AACTTCACTA GTGACTCTCA TTTCTCTGGA 
GCCAGAACGT GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012747.1
CDS	46..660
Translation	MAEDTYSHKMVKTNHRRCRTKFTEEQLKILINTFNQKPYPGYATKQKLALEINTEESRIQIWFQNRRARHGFQKRPEAETLESSQSQGQDQPGVEFQSREARRCRTTYSASQLHTLIKAFMKNPYPGIDSREELAKEIGVPESRVQIWFQNRRSRLLLQRKREPVASLEQEEQGKIPEGLQGAEDTQNGTNFTSDSHFSGARTW

Target ORF information:

RefSeq Version	NM_001012729.1
Organism	Homo sapiens(human)
Definition	Homo sapiens double homeobox A (DUXA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012729.1

ORF Insert Sequence:

ATGGCCGAAG ACACCTATTC ACACAAGATG GTAAAAACAA ATCATAGGCG CTGTCGCACA 
AAATTCACAG AAGAACAGTT GAAAATCCTC ATCAATACCT TCAATCAAAA GCCTTACCCA 
GGTTATGCTA CCAAACAAAA ACTTGCTTTA GAAATCAATA CAGAAGAGTC CAGAATCCAG 
ATTTGGTTTC AGAATCGAAG AGCTAGGCAC GGATTCCAGA AAAGACCAGA AGCTGAGACT 
TTAGAATCAA GCCAGAGCCA GGGGCAAGAT CAACCTGGTG TGGAGTTTCA AAGTAGAGAA 
GCCAGACGGT GTCGTACCAC CTACAGCGCC TCTCAGTTAC ACACTCTCAT CAAGGCATTT 
ATGAAAAACC CATATCCTGG GATTGATTCC AGAGAAGAAC TTGCTAAAGA AATCGGTGTT 
CCAGAGTCAA GAGTCCAAAT TTGGTTCCAA AATCGAAGAT CTAGATTACT TCTCCAGAGA 
AAAAGGGAAC CTGTGGCGTC CTTAGAACAA GAAGAGCAGG GCAAGATTCC TGAGGGACTG 
CAAGGTGCAG AAGATACACA AAATGGCACC AACTTCACTA GTGACTCTCA TTTCTCTGGA 
GCCAGAACGT GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DUXA ( NM_001012729.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001012747.1 Homo sapiens double homeobox A (DUXA), mRNA.

Price & Availability↑

CloneID	OHu04077
Clone ID Related Accession (Same CDS sequence)	NM_001012729.1 , NM_001012729.2
Accession Version	NM_001012729.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 615bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	double homeobox protein A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Anne Booth and Peter Holland. The reference sequence was derived from AC025588.1. On Jun 28, 2019 this sequence version replaced NM_001012729.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.163686.1, SRR5189667.340465.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCCGAAG ACACCTATTC ACACAAGATG GTAAAAACAA ATCATAGGCG CTGTCGCACA 
AAATTCACAG AAGAACAGTT GAAAATCCTC ATCAATACCT TCAATCAAAA GCCTTACCCA 
GGTTATGCTA CCAAACAAAA ACTTGCTTTA GAAATCAATA CAGAAGAGTC CAGAATCCAG 
ATTTGGTTTC AGAATCGAAG AGCTAGGCAC GGATTCCAGA AAAGACCAGA AGCTGAGACT 
TTAGAATCAA GCCAGAGCCA GGGGCAAGAT CAACCTGGTG TGGAGTTTCA AAGTAGAGAA 
GCCAGACGGT GTCGTACCAC CTACAGCGCC TCTCAGTTAC ACACTCTCAT CAAGGCATTT 
ATGAAAAACC CATATCCTGG GATTGATTCC AGAGAAGAAC TTGCTAAAGA AATCGGTGTT 
CCAGAGTCAA GAGTCCAAAT TTGGTTCCAA AATCGAAGAT CTAGATTACT TCTCCAGAGA 
AAAAGGGAAC CTGTGGCGTC CTTAGAACAA GAAGAGCAGG GCAAGATTCC TGAGGGACTG 
CAAGGTGCAG AAGATACACA AAATGGCACC AACTTCACTA GTGACTCTCA TTTCTCTGGA 
GCCAGAACGT GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012747.1
CDS	43..657
Translation	MAEDTYSHKMVKTNHRRCRTKFTEEQLKILINTFNQKPYPGYATKQKLALEINTEESRIQIWFQNRRARHGFQKRPEAETLESSQSQGQDQPGVEFQSREARRCRTTYSASQLHTLIKAFMKNPYPGIDSREELAKEIGVPESRVQIWFQNRRSRLLLQRKREPVASLEQEEQGKIPEGLQGAEDTQNGTNFTSDSHFSGARTW

Target ORF information:

RefSeq Version	NM_001012729.2
Organism	Homo sapiens(human)
Definition	Homo sapiens double homeobox A (DUXA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012729.2

ORF Insert Sequence:

ATGGCCGAAG ACACCTATTC ACACAAGATG GTAAAAACAA ATCATAGGCG CTGTCGCACA 
AAATTCACAG AAGAACAGTT GAAAATCCTC ATCAATACCT TCAATCAAAA GCCTTACCCA 
GGTTATGCTA CCAAACAAAA ACTTGCTTTA GAAATCAATA CAGAAGAGTC CAGAATCCAG 
ATTTGGTTTC AGAATCGAAG AGCTAGGCAC GGATTCCAGA AAAGACCAGA AGCTGAGACT 
TTAGAATCAA GCCAGAGCCA GGGGCAAGAT CAACCTGGTG TGGAGTTTCA AAGTAGAGAA 
GCCAGACGGT GTCGTACCAC CTACAGCGCC TCTCAGTTAC ACACTCTCAT CAAGGCATTT 
ATGAAAAACC CATATCCTGG GATTGATTCC AGAGAAGAAC TTGCTAAAGA AATCGGTGTT 
CCAGAGTCAA GAGTCCAAAT TTGGTTCCAA AATCGAAGAT CTAGATTACT TCTCCAGAGA 
AAAAGGGAAC CTGTGGCGTC CTTAGAACAA GAAGAGCAGG GCAAGATTCC TGAGGGACTG 
CAAGGTGCAG AAGATACACA AAATGGCACC AACTTCACTA GTGACTCTCA TTTCTCTGGA 
GCCAGAACGT GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Wnt signaling and Dupuytren's disease.
The New England journal of medicine365(4)307-17(2011 Jul)
Dolmans GH,Werker PM,Hennies HC,Furniss D,Festen EA,Franke L,Becker K,van der Vlies P,Wolffenbuttel BH,Tinschert S,Toliat MR,Nothnagel M,Franke A,Klopp N,Wichmann HE,N?rnberg P,Giele H,Ophoff RA,Wijmenga C,,,,

Annotation, nomenclature and evolution of four novel homeobox genes expressed in the human germ line.
Gene387(1-2)7-14(2007 Jan)
Booth HA,Holland PW

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DUXA cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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