P4HB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	P4HB
Entrez Gene ID	5034
Full Name	prolyl 4-hydroxylase subunit beta
Synonyms	CLCRP1,DSI,ERBA2L,GIT,P4Hbeta,PDI,PDIA1,PHDB,PO4DB,PO4HB,PROHB
General protein information	Preferred Names prolyl 4-hydroxylase subunit beta Names protein disulfide-isomerase cellular thyroid hormone-binding protein collagen prolyl 4-hydroxylase beta glutathione-insulin transhydrogenase p55 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide prolyl 4-hydroxylase, beta polypeptide protein disulfide isomerase family A, member 1 protein disulfide isomerase-associated 1 protein disulfide isomerase/oxidoreductase protocollagen hydroxylase testicular secretory protein Li 32 thyroid hormone-binding protein p55
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.3
Summary	This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008].
Disorder MIM:	176790
Disorder Html:	Cole-Carpenter syndrome 1, 112240 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_024450777.1	XP_024306545.1	protein disulfide-isomerase isoform X1
NM_000918.4	NP_000909.2	protein disulfide-isomerase precursor
NM_000918.3	NP_000909.2	protein disulfide-isomerase precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	P4HB	XP_540488.2
Mus musculus (house mouse)	P4hb	NP_035162.1
Rattus norvegicus (Norway rat)	P4hb	NP_037130.1
Gallus gallus (chicken)	P4HB	NP_001185639.1
Danio rerio (zebrafish)	p4hb	NP_998529.3
Eremothecium gossypii	AGOS_AFR718W	NP_986266.2
Arabidopsis thaliana (thale cress)	PDIL1-4	NP_851234.1
Xenopus tropicalis (tropical clawed frog)	p4hb	NP_001034820.1
Homo sapiens (human)	P4HB	NP_000909.2
Pan troglodytes (chimpanzee)	P4HB	NP_001233358.1
Drosophila melanogaster (fruit fly)	Pdi	NP_524079.1
Saccharomyces cerevisiae (baker's yeast)	PDI1	NP_009887.1
Neurospora crassa	NCU09223	XP_959167.1
Oryza sativa (rice)	Os02g0100100	NP_001045579.1
Caenorhabditis elegans (roundworm)	pdi-2	NP_508778.1
Arabidopsis thaliana (thale cress)	PDIL1-3	NP_191056.2
	LOC714702	XP_002800695.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012407	XP_551775.3
Bos taurus (cattle)	P4HB	NP_776560.1
Kluyveromyces lactis	KLLA0C01111g	XP_452244.1
Schizosaccharomyces pombe (fission yeast)	SPAC1F5.02	NP_592871.1
Magnaporthe oryzae (rice blast fungus)	MGG_05753	XP_003710672.1

Gene Ontology

The following P4HB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the P4HB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25382	NM_000918.4 Latest version!	Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu104410	XM_024450777.1 Latest version!	Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu25382	NM_000918.3	Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

P4HB ( NM_000918.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000909.2 Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), mRNA.

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CloneID	OHu25382
Clone ID Related Accession (Same CDS sequence)	NM_000918.4 , NM_000918.3
Accession Version	NM_000918.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	protein disulfide-isomerase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB466371.1 and BC010859.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000918.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.5600.1, HM005572.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000331483.9/ ENSP00000327801.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGCGCC GCGCTCTGCT GTGCCTGGCC GTGGCCGCCC TGGTGCGCGC CGACGCCCCC 
GAGGAGGAGG ACCACGTCCT GGTGCTGCGG AAAAGCAACT TCGCGGAGGC GCTGGCGGCC 
CACAAGTACC TGCTGGTGGA GTTCTATGCC CCTTGGTGTG GCCACTGCAA GGCTCTGGCC 
CCTGAGTATG CCAAAGCCGC TGGGAAGCTG AAGGCAGAAG GTTCCGAGAT CAGGTTGGCC 
AAGGTGGACG CCACGGAGGA GTCTGACCTG GCCCAGCAGT ACGGCGTGCG CGGCTATCCC 
ACCATCAAGT TCTTCAGGAA TGGAGACACG GCTTCCCCCA AGGAATATAC AGCTGGCAGA 
GAGGCTGATG ACATCGTGAA CTGGCTGAAG AAGCGCACGG GCCCGGCTGC CACCACCCTG 
CCTGACGGCG CAGCTGCAGA GTCCTTGGTG GAGTCCAGCG AGGTGGCTGT CATCGGCTTC 
TTCAAGGACG TGGAGTCGGA CTCTGCCAAG CAGTTTTTGC AGGCAGCAGA GGCCATCGAT 
GACATACCAT TTGGGATCAC TTCCAACAGT GACGTGTTCT CCAAATACCA GCTCGACAAA 
GATGGGGTTG TCCTCTTTAA GAAGTTTGAT GAAGGCCGGA ACAACTTTGA AGGGGAGGTC 
ACCAAGGAGA ACCTGCTGGA CTTTATCAAA CACAACCAGC TGCCCCTTGT CATCGAGTTC 
ACCGAGCAGA CAGCCCCGAA GATTTTTGGA GGTGAAATCA AGACTCACAT CCTGCTGTTC 
TTGCCCAAGA GTGTGTCTGA CTATGACGGC AAACTGAGCA ACTTCAAAAC AGCAGCCGAG 
AGCTTCAAGG GCAAGATCCT GTTCATCTTC ATCGACAGCG ACCACACCGA CAACCAGCGC 
ATCCTCGAGT TCTTTGGCCT GAAGAAGGAA GAGTGCCCGG CCGTGCGCCT CATCACCCTG 
GAGGAGGAGA TGACCAAGTA CAAGCCCGAA TCGGAGGAGC TGACGGCAGA GAGGATCACA 
GAGTTCTGCC ACCGCTTCCT GGAGGGCAAA ATCAAGCCCC ACCTGATGAG CCAGGAGCTG 
CCGGAGGACT GGGACAAGCA GCCTGTCAAG GTGCTTGTTG GGAAGAACTT TGAAGACGTG 
GCTTTTGATG AGAAAAAAAA CGTCTTTGTG GAGTTCTATG CCCCATGGTG TGGTCACTGC 
AAACAGTTGG CTCCCATTTG GGATAAACTG GGAGAGACGT ACAAGGACCA TGAGAACATC 
GTCATCGCCA AGATGGACTC GACTGCCAAC GAGGTGGAGG CCGTCAAAGT GCACAGCTTC 
CCCACACTCA AGTTCTTTCC TGCCAGTGCC GACAGGACGG TCATTGATTA CAACGGGGAA 
CGCACGCTGG ATGGTTTTAA GAAATTCCTG GAGAGCGGTG GCCAGGATGG GGCAGGGGAT 
GATGACGATC TCGAGGACCT GGAAGAAGCA GAGGAGCCAG ACATGGAGGA AGACGATGAT 
CAGAAAGCTG TGAAAGATGA ACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000909.2
CDS	65..1591
Translation	MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL

Target ORF information:

RefSeq Version	NM_000918.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000918.4

ORF Insert Sequence:

ATGCTGCGCC GCGCTCTGCT GTGCCTGGCC GTGGCCGCCC TGGTGCGCGC CGACGCCCCC 
GAGGAGGAGG ACCACGTCCT GGTGCTGCGG AAAAGCAACT TCGCGGAGGC GCTGGCGGCC 
CACAAGTACC TGCTGGTGGA GTTCTATGCC CCTTGGTGTG GCCACTGCAA GGCTCTGGCC 
CCTGAGTATG CCAAAGCCGC TGGGAAGCTG AAGGCAGAAG GTTCCGAGAT CAGGTTGGCC 
AAGGTGGACG CCACGGAGGA GTCTGACCTG GCCCAGCAGT ACGGCGTGCG CGGCTATCCC 
ACCATCAAGT TCTTCAGGAA TGGAGACACG GCTTCCCCCA AGGAATATAC AGCTGGCAGA 
GAGGCTGATG ACATCGTGAA CTGGCTGAAG AAGCGCACGG GCCCGGCTGC CACCACCCTG 
CCTGACGGCG CAGCTGCAGA GTCCTTGGTG GAGTCCAGCG AGGTGGCTGT CATCGGCTTC 
TTCAAGGACG TGGAGTCGGA CTCTGCCAAG CAGTTTTTGC AGGCAGCAGA GGCCATCGAT 
GACATACCAT TTGGGATCAC TTCCAACAGT GACGTGTTCT CCAAATACCA GCTCGACAAA 
GATGGGGTTG TCCTCTTTAA GAAGTTTGAT GAAGGCCGGA ACAACTTTGA AGGGGAGGTC 
ACCAAGGAGA ACCTGCTGGA CTTTATCAAA CACAACCAGC TGCCCCTTGT CATCGAGTTC 
ACCGAGCAGA CAGCCCCGAA GATTTTTGGA GGTGAAATCA AGACTCACAT CCTGCTGTTC 
TTGCCCAAGA GTGTGTCTGA CTATGACGGC AAACTGAGCA ACTTCAAAAC AGCAGCCGAG 
AGCTTCAAGG GCAAGATCCT GTTCATCTTC ATCGACAGCG ACCACACCGA CAACCAGCGC 
ATCCTCGAGT TCTTTGGCCT GAAGAAGGAA GAGTGCCCGG CCGTGCGCCT CATCACCCTG 
GAGGAGGAGA TGACCAAGTA CAAGCCCGAA TCGGAGGAGC TGACGGCAGA GAGGATCACA 
GAGTTCTGCC ACCGCTTCCT GGAGGGCAAA ATCAAGCCCC ACCTGATGAG CCAGGAGCTG 
CCGGAGGACT GGGACAAGCA GCCTGTCAAG GTGCTTGTTG GGAAGAACTT TGAAGACGTG 
GCTTTTGATG AGAAAAAAAA CGTCTTTGTG GAGTTCTATG CCCCATGGTG TGGTCACTGC 
AAACAGTTGG CTCCCATTTG GGATAAACTG GGAGAGACGT ACAAGGACCA TGAGAACATC 
GTCATCGCCA AGATGGACTC GACTGCCAAC GAGGTGGAGG CCGTCAAAGT GCACAGCTTC 
CCCACACTCA AGTTCTTTCC TGCCAGTGCC GACAGGACGG TCATTGATTA CAACGGGGAA 
CGCACGCTGG ATGGTTTTAA GAAATTCCTG GAGAGCGGTG GCCAGGATGG GGCAGGGGAT 
GATGACGATC TCGAGGACCT GGAAGAAGCA GAGGAGCCAG ACATGGAGGA AGACGATGAT 
CAGAAAGCTG TGAAAGATGA ACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P4HB ( NM_000918.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000909.2 Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), mRNA.

Price & Availability↑

CloneID	OHu25382
Clone ID Related Accession (Same CDS sequence)	NM_000918.4 , NM_000918.3
Accession Version	NM_000918.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	protein disulfide-isomerase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU131354.1, DB466371.1, BC010859.1 and CA412209.1. This sequence is a reference standard in the RefSeqGene project. On Jan 5, 2007 this sequence version replaced NM_000918.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HM005572.1, SRR1163655.109560.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGCGCC GCGCTCTGCT GTGCCTGGCC GTGGCCGCCC TGGTGCGCGC CGACGCCCCC 
GAGGAGGAGG ACCACGTCCT GGTGCTGCGG AAAAGCAACT TCGCGGAGGC GCTGGCGGCC 
CACAAGTACC TGCTGGTGGA GTTCTATGCC CCTTGGTGTG GCCACTGCAA GGCTCTGGCC 
CCTGAGTATG CCAAAGCCGC TGGGAAGCTG AAGGCAGAAG GTTCCGAGAT CAGGTTGGCC 
AAGGTGGACG CCACGGAGGA GTCTGACCTG GCCCAGCAGT ACGGCGTGCG CGGCTATCCC 
ACCATCAAGT TCTTCAGGAA TGGAGACACG GCTTCCCCCA AGGAATATAC AGCTGGCAGA 
GAGGCTGATG ACATCGTGAA CTGGCTGAAG AAGCGCACGG GCCCGGCTGC CACCACCCTG 
CCTGACGGCG CAGCTGCAGA GTCCTTGGTG GAGTCCAGCG AGGTGGCTGT CATCGGCTTC 
TTCAAGGACG TGGAGTCGGA CTCTGCCAAG CAGTTTTTGC AGGCAGCAGA GGCCATCGAT 
GACATACCAT TTGGGATCAC TTCCAACAGT GACGTGTTCT CCAAATACCA GCTCGACAAA 
GATGGGGTTG TCCTCTTTAA GAAGTTTGAT GAAGGCCGGA ACAACTTTGA AGGGGAGGTC 
ACCAAGGAGA ACCTGCTGGA CTTTATCAAA CACAACCAGC TGCCCCTTGT CATCGAGTTC 
ACCGAGCAGA CAGCCCCGAA GATTTTTGGA GGTGAAATCA AGACTCACAT CCTGCTGTTC 
TTGCCCAAGA GTGTGTCTGA CTATGACGGC AAACTGAGCA ACTTCAAAAC AGCAGCCGAG 
AGCTTCAAGG GCAAGATCCT GTTCATCTTC ATCGACAGCG ACCACACCGA CAACCAGCGC 
ATCCTCGAGT TCTTTGGCCT GAAGAAGGAA GAGTGCCCGG CCGTGCGCCT CATCACCCTG 
GAGGAGGAGA TGACCAAGTA CAAGCCCGAA TCGGAGGAGC TGACGGCAGA GAGGATCACA 
GAGTTCTGCC ACCGCTTCCT GGAGGGCAAA ATCAAGCCCC ACCTGATGAG CCAGGAGCTG 
CCGGAGGACT GGGACAAGCA GCCTGTCAAG GTGCTTGTTG GGAAGAACTT TGAAGACGTG 
GCTTTTGATG AGAAAAAAAA CGTCTTTGTG GAGTTCTATG CCCCATGGTG TGGTCACTGC 
AAACAGTTGG CTCCCATTTG GGATAAACTG GGAGAGACGT ACAAGGACCA TGAGAACATC 
GTCATCGCCA AGATGGACTC GACTGCCAAC GAGGTGGAGG CCGTCAAAGT GCACAGCTTC 
CCCACACTCA AGTTCTTTCC TGCCAGTGCC GACAGGACGG TCATTGATTA CAACGGGGAA 
CGCACGCTGG ATGGTTTTAA GAAATTCCTG GAGAGCGGTG GCCAGGATGG GGCAGGGGAT 
GATGACGATC TCGAGGACCT GGAAGAAGCA GAGGAGCCAG ACATGGAGGA AGACGATGAT 
CAGAAAGCTG TGAAAGATGA ACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000909.2
CDS	198..1724
Translation	MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL

Target ORF information:

RefSeq Version	NM_000918.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000918.3

ORF Insert Sequence:

ATGCTGCGCC GCGCTCTGCT GTGCCTGGCC GTGGCCGCCC TGGTGCGCGC CGACGCCCCC 
GAGGAGGAGG ACCACGTCCT GGTGCTGCGG AAAAGCAACT TCGCGGAGGC GCTGGCGGCC 
CACAAGTACC TGCTGGTGGA GTTCTATGCC CCTTGGTGTG GCCACTGCAA GGCTCTGGCC 
CCTGAGTATG CCAAAGCCGC TGGGAAGCTG AAGGCAGAAG GTTCCGAGAT CAGGTTGGCC 
AAGGTGGACG CCACGGAGGA GTCTGACCTG GCCCAGCAGT ACGGCGTGCG CGGCTATCCC 
ACCATCAAGT TCTTCAGGAA TGGAGACACG GCTTCCCCCA AGGAATATAC AGCTGGCAGA 
GAGGCTGATG ACATCGTGAA CTGGCTGAAG AAGCGCACGG GCCCGGCTGC CACCACCCTG 
CCTGACGGCG CAGCTGCAGA GTCCTTGGTG GAGTCCAGCG AGGTGGCTGT CATCGGCTTC 
TTCAAGGACG TGGAGTCGGA CTCTGCCAAG CAGTTTTTGC AGGCAGCAGA GGCCATCGAT 
GACATACCAT TTGGGATCAC TTCCAACAGT GACGTGTTCT CCAAATACCA GCTCGACAAA 
GATGGGGTTG TCCTCTTTAA GAAGTTTGAT GAAGGCCGGA ACAACTTTGA AGGGGAGGTC 
ACCAAGGAGA ACCTGCTGGA CTTTATCAAA CACAACCAGC TGCCCCTTGT CATCGAGTTC 
ACCGAGCAGA CAGCCCCGAA GATTTTTGGA GGTGAAATCA AGACTCACAT CCTGCTGTTC 
TTGCCCAAGA GTGTGTCTGA CTATGACGGC AAACTGAGCA ACTTCAAAAC AGCAGCCGAG 
AGCTTCAAGG GCAAGATCCT GTTCATCTTC ATCGACAGCG ACCACACCGA CAACCAGCGC 
ATCCTCGAGT TCTTTGGCCT GAAGAAGGAA GAGTGCCCGG CCGTGCGCCT CATCACCCTG 
GAGGAGGAGA TGACCAAGTA CAAGCCCGAA TCGGAGGAGC TGACGGCAGA GAGGATCACA 
GAGTTCTGCC ACCGCTTCCT GGAGGGCAAA ATCAAGCCCC ACCTGATGAG CCAGGAGCTG 
CCGGAGGACT GGGACAAGCA GCCTGTCAAG GTGCTTGTTG GGAAGAACTT TGAAGACGTG 
GCTTTTGATG AGAAAAAAAA CGTCTTTGTG GAGTTCTATG CCCCATGGTG TGGTCACTGC 
AAACAGTTGG CTCCCATTTG GGATAAACTG GGAGAGACGT ACAAGGACCA TGAGAACATC 
GTCATCGCCA AGATGGACTC GACTGCCAAC GAGGTGGAGG CCGTCAAAGT GCACAGCTTC 
CCCACACTCA AGTTCTTTCC TGCCAGTGCC GACAGGACGG TCATTGATTA CAACGGGGAA 
CGCACGCTGG ATGGTTTTAA GAAATTCCTG GAGAGCGGTG GCCAGGATGG GGCAGGGGAT 
GATGACGATC TCGAGGACCT GGAAGAAGCA GAGGAGCCAG ACATGGAGGA AGACGATGAT 
CAGAAAGCTG TGAAAGATGA ACTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

P4HB ( XM_024450777.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306545.1 Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104410
Clone ID Related Accession (Same CDS sequence)	XM_024450777.1
Accession Version	XM_024450777.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein disulfide-isomerase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCGCC GCGCTCTGCT GTGCCTGGCC GTGGCCGCCC TGGTGCGCGC CGACGCCCCC 
GAGGAGGAGG ACCACGTCCT GGTGCTGCGG AAAAGCAACT TCGCGGAGGC GCTGGCGGCC 
CACAAGTACC TGCTGGTGGA GTTCTATGCC CCTTGGTGTG GCCACTGCAA GGCTCTGGCC 
CCTGAGTATG CCAAAGCCGC TGGGAAGCTG AAGGCAGAAG GTTCCGAGAT CAGGTTGGCC 
AAGGTGGACG CCACGGAGGA GTCTGACCTG GCCCAGCAGT ACGGCGTGCG CGGCTATCCC 
ACCATCAAGT TCTTCAGGAA TGGAGACACG GCTTCCCCCA AGGAATATAC AGCTGGCAGA 
GAGGCTGATG ACATCGTGAA CTGGCTGAAG AAGCGCACGG GCCCGGCTGC CACCACCCTG 
CCTGACGGCG CAGCTGCAGA GTCCTTGGTG GAGTCCAGCG AGGTGGCTGT CATCGGCTTC 
TTCAAGGACG TGGAGTCGGA CTCTGCCAAG CAGTTTTTGC AGGCAGCAGA GGCCATCGAT 
GACATACCAT TTGGGATCAC TTCCAACAGT GACGTGTTCT CCAAATACCA GCTCGACAAA 
GATGGGGTTG TCCTCTTTAA GAAGTTTGAT GAAGGCCGGA ACAACTTTGA AGGGGAGGTC 
ACCAAGGAGA ACCTGCTGGA CTTTATCAAA CACAACCAGC TGCCCCTTGT CATCGAGTTC 
ACCGAGCAGA CAGCCCCGAA GATTTTTGGA GGTGAAATCA AGACTCACAT CCTGCTGTTC 
TTGCCCAAGA GTGTGTCTGA CTATGACGGC AAACTGAGCA ACTTCAAAAC AGCAGCCGAG 
AGCTTCAAGG GCAAGATCCT GTTCATCTTC ATCGACAGCG ACCACACCGA CAACCAGCGC 
ATCCTCGAGT TCTTTGGCCT GAAGAAGGAA GAGTGCCCGG CCGTGCGCCT CATCACCCTG 
GAGGAGGAGA TGACCAAGTA CAAGCCCGAA TCGGAGGAGC TGACGGCAGA GAGGATCACA 
GAGTTCTGCC ACCGCTTCCT GGAGGGCAAA ATCAAGCCCC ACCTGATGAG CCAGGAGCTG 
CCGGAGGACT GGGACAAGCA GCCTGTCAAG GTGCTTGTTG GGAAGAACTT TGAAGACGTG 
GCTTTTGATG AGAAAAAAAA CGTCTTTGTG GAGTTCTGTA AGTGTTGCCC TTTCAGCTCC 
CCAGGTCCGT GCCACCAGGG CACGCGCAAG GTAGGCAGAC TCCTGGGGAA GCGTCTGCCA 
GTGGCTTTGT GTCCAGGACA CACCCTAGAA CTGCTTTCTT TTCAGATGCC CCATGGTGTG 
GTCACTGCAA ACAGTTGGCT CCCATTTGGG ATAAACTGGG AGAGACGTAC AAGGACCATG 
AGAACATCGT CATCGCCAAG ATGGACTCGA CTGCCAACGA GGTGGAGGCC GTCAAAGTGC 
ACAGCTTCCC CACACTCAAG TTCTTTCCTG CCAGTGCCGA CAGGACGGTC ATTGATTACA 
ACGGGGAACG CACGCTGGAT GGTTTTAAGA AATTCCTGGA GAGCGGTGGC CAGGATGGGG 
CAGGGGATGA TGACGATCTC GAGGACCTGG AAGAAGCAGA GGAGCCAGAC ATGGAGGAAG 
ACGATGATCA GAAAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306545.1
CDS	65..1705
Translation	MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFCKCCPFSSPGPCHQGTRKVGRLLGKRLPVALCPGHTLELLSFQMPHGVVTANSWLPFGINWERRTRTMRTSSSPRWTRLPTRWRPSKCTASPHSSSFLPVPTGRSLITTGNARWMVLRNSWRAVARMGQGMMTISRTWKKQRSQTWRKTMIRKL

Target ORF information:

RefSeq Version	XM_024450777.1
Organism	Homo sapiens(human)
Definition	Homo sapiens prolyl 4-hydroxylase subunit beta (P4HB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450777.1

ORF Insert Sequence:

ATGCTGCGCC GCGCTCTGCT GTGCCTGGCC GTGGCCGCCC TGGTGCGCGC CGACGCCCCC 
GAGGAGGAGG ACCACGTCCT GGTGCTGCGG AAAAGCAACT TCGCGGAGGC GCTGGCGGCC 
CACAAGTACC TGCTGGTGGA GTTCTATGCC CCTTGGTGTG GCCACTGCAA GGCTCTGGCC 
CCTGAGTATG CCAAAGCCGC TGGGAAGCTG AAGGCAGAAG GTTCCGAGAT CAGGTTGGCC 
AAGGTGGACG CCACGGAGGA GTCTGACCTG GCCCAGCAGT ACGGCGTGCG CGGCTATCCC 
ACCATCAAGT TCTTCAGGAA TGGAGACACG GCTTCCCCCA AGGAATATAC AGCTGGCAGA 
GAGGCTGATG ACATCGTGAA CTGGCTGAAG AAGCGCACGG GCCCGGCTGC CACCACCCTG 
CCTGACGGCG CAGCTGCAGA GTCCTTGGTG GAGTCCAGCG AGGTGGCTGT CATCGGCTTC 
TTCAAGGACG TGGAGTCGGA CTCTGCCAAG CAGTTTTTGC AGGCAGCAGA GGCCATCGAT 
GACATACCAT TTGGGATCAC TTCCAACAGT GACGTGTTCT CCAAATACCA GCTCGACAAA 
GATGGGGTTG TCCTCTTTAA GAAGTTTGAT GAAGGCCGGA ACAACTTTGA AGGGGAGGTC 
ACCAAGGAGA ACCTGCTGGA CTTTATCAAA CACAACCAGC TGCCCCTTGT CATCGAGTTC 
ACCGAGCAGA CAGCCCCGAA GATTTTTGGA GGTGAAATCA AGACTCACAT CCTGCTGTTC 
TTGCCCAAGA GTGTGTCTGA CTATGACGGC AAACTGAGCA ACTTCAAAAC AGCAGCCGAG 
AGCTTCAAGG GCAAGATCCT GTTCATCTTC ATCGACAGCG ACCACACCGA CAACCAGCGC 
ATCCTCGAGT TCTTTGGCCT GAAGAAGGAA GAGTGCCCGG CCGTGCGCCT CATCACCCTG 
GAGGAGGAGA TGACCAAGTA CAAGCCCGAA TCGGAGGAGC TGACGGCAGA GAGGATCACA 
GAGTTCTGCC ACCGCTTCCT GGAGGGCAAA ATCAAGCCCC ACCTGATGAG CCAGGAGCTG 
CCGGAGGACT GGGACAAGCA GCCTGTCAAG GTGCTTGTTG GGAAGAACTT TGAAGACGTG 
GCTTTTGATG AGAAAAAAAA CGTCTTTGTG GAGTTCTGTA AGTGTTGCCC TTTCAGCTCC 
CCAGGTCCGT GCCACCAGGG CACGCGCAAG GTAGGCAGAC TCCTGGGGAA GCGTCTGCCA 
GTGGCTTTGT GTCCAGGACA CACCCTAGAA CTGCTTTCTT TTCAGATGCC CCATGGTGTG 
GTCACTGCAA ACAGTTGGCT CCCATTTGGG ATAAACTGGG AGAGACGTAC AAGGACCATG 
AGAACATCGT CATCGCCAAG ATGGACTCGA CTGCCAACGA GGTGGAGGCC GTCAAAGTGC 
ACAGCTTCCC CACACTCAAG TTCTTTCCTG CCAGTGCCGA CAGGACGGTC ATTGATTACA 
ACGGGGAACG CACGCTGGAT GGTTTTAAGA AATTCCTGGA GAGCGGTGGC CAGGATGGGG 
CAGGGGATGA TGACGATCTC GAGGACCTGG AAGAAGCAGA GGAGCCAGAC ATGGAGGAAG 
ACGATGATCA GAAAGCTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

見積依頼

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03-6811-6572

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03-6811-6573
050-3174-7589(受注専用)

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オンライン注文

P4HB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報