SPANXN1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SPANXN1
Entrez Gene ID	494118
Full Name	SPANX family member N1
Synonyms	CT11.6
General protein information	Preferred Names SPANX family member N1 Names sperm protein associated with the nucleus on the X chromosome N1 cancer/testis antigen family 11, member 6 nuclear-associated protein SPAN-Xn1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq27.3
Summary	This gene represents one of several duplicated family members that are located on chromosome X. This gene family encodes proteins that play a role in spermiogenesis. These proteins represent a specific subgroup of cancer/testis-associated antigens, and they may be candidates for tumor vaccines. This family member belongs to a subgroup of related genes that are present in all primates and rats and mice, and thus, it represents one of the ancestral family members. [provided by RefSeq, May 2010].
Disorder MIM:	300664

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009614.3	NP_001009614.1	sperm protein associated with the nucleus on the X chromosome N1
NM_001009614.2	NP_001009614.1	sperm protein associated with the nucleus on the X chromosome N1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Hominoid-specific SPANXA/D genes demonstrate differential expression in individuals and protein localization to a distinct nuclear envelope domain during spermatid morphogenesis.
Westbrook VA, Schoppee PD, Vanage GR, Klotz KL, Diekman AB, Flickinger CJ, Coppola MA, Herr JC
Molecular human reproduction12(11)703-16(2006 Nov)

The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids.
Kouprina N, Mullokandov M, Rogozin IB, Collins NK, Solomon G, Otstot J, Risinger JI, Koonin EV, Barrett JC, Larionov V
Proceedings of the National Academy of Sciences of the United States of America101(9)3077-82(2004 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SPANXN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPANXN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19424	NM_001009614.3 Latest version!	Homo sapiens SPANX family member N1 (SPANXN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu19424	NM_001009614.2	Homo sapiens SPANX family member N1 (SPANXN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SPANXN1 ( NM_001009614.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009614.1 Homo sapiens SPANX family member N1 (SPANXN1), mRNA.

Price & Availability↑

CloneID	OHu19424
Clone ID Related Accession (Same CDS sequence)	NM_001009614.3 , NM_001009614.2
Accession Version	NM_001009614.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 219bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	sperm protein associated with the nucleus on the X chromosome N1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL713923.2, DQ336118.1 and AL356499.16. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_001009614.2. ##Evidence-Data-START## Transcript exon combination :: DQ336118.1, DQ336119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000370493.4/ ENSP00000359524.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGAACAGC CCACTTCAAG CATCAATGGG GAGAAGAGGA AGAGCCCCTG TGAATCCAAC 
AATGAAAATG ATGAGATGCA GGAGACACCA AACAGGGACT TAGCCCCCGA ACCGAGTTTG 
AAAAAGATGA AAACGTCAGA ATATTCAACA GTATTAGCGT TTTGCTACAG GAAAGCTAAG 
AAAATACATT CAAATCAACT GGAGAATGAC CAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009614.1
CDS	85..303
Translation	MEQPTSSINGEKRKSPCESNNENDEMQETPNRDLAPEPSLKKMKTSEYSTVLAFCYRKAKKIHSNQLENDQS

Target ORF information:

RefSeq Version	NM_001009614.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SPANX family member N1 (SPANXN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009614.3

ORF Insert Sequence:

ATGGAACAGC CCACTTCAAG CATCAATGGG GAGAAGAGGA AGAGCCCCTG TGAATCCAAC 
AATGAAAATG ATGAGATGCA GGAGACACCA AACAGGGACT TAGCCCCCGA ACCGAGTTTG 
AAAAAGATGA AAACGTCAGA ATATTCAACA GTATTAGCGT TTTGCTACAG GAAAGCTAAG 
AAAATACATT CAAATCAACT GGAGAATGAC CAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SPANXN1 ( NM_001009614.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009614.1 Homo sapiens SPANX family member N1 (SPANXN1), mRNA.

Price & Availability↑

CloneID	OHu19424
Clone ID Related Accession (Same CDS sequence)	NM_001009614.3 , NM_001009614.2
Accession Version	NM_001009614.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 219bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	sperm protein associated with the nucleus on the X chromosome N1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ336118.1 and AL356499.16. This sequence is a reference standard in the RefSeqGene project. On Mar 22, 2007 this sequence version replaced NM_001009614.1. ##Evidence-Data-START## Transcript exon combination :: DQ336118.1, DQ336119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGGAACAGC CCACTTCAAG CATCAATGGG GAGAAGAGGA AGAGCCCCTG TGAATCCAAC 
AATGAAAATG ATGAGATGCA GGAGACACCA AACAGGGACT TAGCCCCCGA ACCGAGTTTG 
AAAAAGATGA AAACGTCAGA ATATTCAACA GTATTAGCGT TTTGCTACAG GAAAGCTAAG 
AAAATACATT CAAATCAACT GGAGAATGAC CAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009614.1
CDS	1..219
Translation	MEQPTSSINGEKRKSPCESNNENDEMQETPNRDLAPEPSLKKMKTSEYSTVLAFCYRKAKKIHSNQLENDQS

Target ORF information:

RefSeq Version	NM_001009614.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SPANX family member N1 (SPANXN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009614.2

ORF Insert Sequence:

ATGGAACAGC CCACTTCAAG CATCAATGGG GAGAAGAGGA AGAGCCCCTG TGAATCCAAC 
AATGAAAATG ATGAGATGCA GGAGACACCA AACAGGGACT TAGCCCCCGA ACCGAGTTTG 
AAAAAGATGA AAACGTCAGA ATATTCAACA GTATTAGCGT TTTGCTACAG GAAAGCTAAG 
AAAATACATT CAAATCAACT GGAGAATGAC CAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hominoid-specific SPANXA/D genes demonstrate differential expression in individuals and protein localization to a distinct nuclear envelope domain during spermatid morphogenesis.
Molecular human reproduction12(11)703-16(2006 Nov)
Westbrook VA,Schoppee PD,Vanage GR,Klotz KL,Diekman AB,Flickinger CJ,Coppola MA,Herr JC

The SPANX gene family of cancer/testis-specific antigens: rapid evolution and amplification in African great apes and hominids.
Proceedings of the National Academy of Sciences of the United States of America101(9)3077-82(2004 Mar)
Kouprina N,Mullokandov M,Rogozin IB,Collins NK,Solomon G,Otstot J,Risinger JI,Koonin EV,Barrett JC,Larionov V

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SPANXN1 cDNA ORF clone, Homo sapiens(human)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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