EID3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EID3
Entrez Gene ID	493861
Full Name	EP300 interacting inhibitor of differentiation 3
Synonyms	NS4EB,NSE4B,NSMCE4B
General protein information	Preferred Names EP300 interacting inhibitor of differentiation 3 Names EP300-interacting inhibitor of differentiation 3 E1A-like inhibitor of differentiation 3 EID-1-like inhibitor of differentiation 3 EID-3 non-SMC element 4 homolog B non-structural maintenance of chromosomes element 4 homolog B testis tissue sperm-binding protein Li 96mP
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q23.3
Disorder MIM:	612986

mRNA and Protein(s)

mRNA	Protein	Name
NM_001008394.2	NP_001008395.1	EP300-interacting inhibitor of differentiation 3
NM_001008394.3	NP_001008395.1	EP300-interacting inhibitor of differentiation 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	EID3	NP_001008395.1
Pan troglodytes (chimpanzee)	EID3	XP_001159521.1
	EID3	XP_001088807.2
Bos taurus (cattle)	EID3	NP_001093782.1
Mus musculus (house mouse)	Eid3	NP_079775.2
Rattus norvegicus (Norway rat)	Eid3	NP_001037769.2
Schizosaccharomyces pombe (fission yeast)	nse4	NP_001018837.1
Canis lupus familiaris (dog)	EID3	XP_005626020.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

EID3 directly associates with DNMT3A during transdifferentiation of human umbilical cord mesenchymal stem cells to NPC-like cells.
Luo L, Chen WJ, Yin JQ, Xu RX
Scientific reports740463(2017 Jan)

Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
Ji Y, Schaid DJ, Desta Z, Kubo M, Batzler AJ, Snyder K, Mushiroda T, Kamatani N, Ogburn E, Hall-Flavin D, Flockhart D, Nakamura Y, Mrazek DA, Weinshilboum RM
British journal of clinical pharmacology78(2)373-83(2014 Aug)

Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families.
Hudson JJ, Bednarova K, Kozakova L, Liao C, Guerineau M, Colnaghi R, Vidot S, Marek J, Bathula SR, Lehmann AR, Palecek J
PloS one6(2)e17270(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EID3 acts as an inhibitor of CBP/p300-dependent transcription in a tissue-specific manner.
Title: EID3 is a novel EID family member and an inhibitor of CBP-dependent co-activation.

The following EID3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EID3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55906	NM_001008394.3 Latest version!	Homo sapiens EP300 interacting inhibitor of differentiation 3 (EID3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu55906	NM_001008394.2	Homo sapiens EP300 interacting inhibitor of differentiation 3 (EID3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EID3 ( NM_001008394.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001008395.1 Homo sapiens EP300 interacting inhibitor of differentiation 3 (EID3), mRNA.

Price & Availability↑

CloneID	OHu55906
Clone ID Related Accession (Same CDS sequence)	NM_001008394.2 , NM_001008394.3
Accession Version	NM_001008394.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-29
Organism	Homo sapiens(human)
Product	EP300-interacting inhibitor of differentiation 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI461575.1 and BC027612.2. On Jul 6, 2011 this sequence version replaced NM_001008394.1.

ATGAAGATGG ATGTGTCAGT GAGGGCCGCG GGCTGCTCCG ACGACCTCAG CTCTGGGGAG 
GCCGACGTAG ACCCAAAGCT CCTGGAGCTC ACCGCTGACG AGGAGAAGTG CCGCAGCATC 
CGCAGGCAGT ACCGGCAGCT CATGTACTGC GTGCGGCAGA ACCGGGAGGA CATCGTGAGC 
TCGGCGAACA ACTCCTTAAC CGAGGCTCTG GAGGAAGCCA ACGTCCTCTT TGATGGCGTG 
AGCCGAACCA GAGAAGCAGC CCTCGACGCC CGGTTTCTTG TTATGGCTTC TGATTTGGGT 
AAAGAAAAGG CAAAGCAGTT AAACTCAGAT ATGAACTTCT TTAATCAGTT AGCATTTTGT 
GACTTTCTGT TTCTGTTCGT GGGTCTGAAT TGGATGGAAG GCGATCCTGA CAAGTTGAGT 
GATTGTGATG ATAGCATAGC TCTTTCCTTC TGGAAGGCAA TAGAAAAGGA AGCAACATCC 
TGGATGGTAA AAGCTGAGAC ATTCCATTTT GTTTTTGGTT CATTCAAGCT AGAACGTTCT 
GCACCAAAGC CCCGACTTGA ACACCAGAAA AAAGTTCGCA AGATGGAAGA AAATGGCAAC 
ATGCCTACAA AGTTGCAGAA GTTGGACCTG AGTAGTTATC CAGAAGCGAC AGAAAAAAAC 
GTAGAAAGGA TTTTGGGATT GTTGCAAACC TACTTTCGAA AGTATCCTGA TACTCCTGTG 
TCCTATTTTG AGTTTGTGAT TGATCCAAAC TCTTTTTCTC GTACTGTGGA GAATATATTT 
TATGTTTCTT TTATTGTAAG AGATGGTTTT GCAAGAATAA GGCTTGATGA AGACAGGCTG 
CCAATATTAG AGCCGATGAA TGTTAACCAA ATGGGTGAGG GAAATGATTC CAGTTGCCAT 
GGCAGGAAAC AGGGAGTTAT ATCTTTGACT TTACAGGAGT GGAAAAACAT TGTGGCAGCT 
TTTGAAATTT CTGAGGCTAT GATTACATAC TCCTCATACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008395.1
CDS	204..1205
Translation	MKMDVSVRAAGCSDDLSSGEADVDPKLLELTADEEKCRSIRRQYRQLMYCVRQNREDIVSSANNSLTEALEEANVLFDGVSRTREAALDARFLVMASDLGKEKAKQLNSDMNFFNQLAFCDFLFLFVGLNWMEGDPDKLSDCDDSIALSFWKAIEKEATSWMVKAETFHFVFGSFKLERSAPKPRLEHQKKVRKMEENGNMPTKLQKLDLSSYPEATEKNVERILGLLQTYFRKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIVRDGFARIRLDEDRLPILEPMNVNQMGEGNDSSCHGRKQGVISLTLQEWKNIVAAFEISEAMITYSSY

Target ORF information:

RefSeq Version	NM_001008394.2
Organism	Homo sapiens(human)
Definition	Homo sapiens EP300 interacting inhibitor of differentiation 3 (EID3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008394.2

ORF Insert Sequence:

ATGAAGATGG ATGTGTCAGT GAGGGCCGCG GGCTGCTCCG ACGACCTCAG CTCTGGGGAG 
GCCGACGTAG ACCCAAAGCT CCTGGAGCTC ACCGCTGACG AGGAGAAGTG CCGCAGCATC 
CGCAGGCAGT ACCGGCAGCT CATGTACTGC GTGCGGCAGA ACCGGGAGGA CATCGTGAGC 
TCGGCGAACA ACTCCTTAAC CGAGGCTCTG GAGGAAGCCA ACGTCCTCTT TGATGGCGTG 
AGCCGAACCA GAGAAGCAGC CCTCGACGCC CGGTTTCTTG TTATGGCTTC TGATTTGGGT 
AAAGAAAAGG CAAAGCAGTT AAACTCAGAT ATGAACTTCT TTAATCAGTT AGCATTTTGT 
GACTTTCTGT TTCTGTTCGT GGGTCTGAAT TGGATGGAAG GCGATCCTGA CAAGTTGAGT 
GATTGTGATG ATAGCATAGC TCTTTCCTTC TGGAAGGCAA TAGAAAAGGA AGCAACATCC 
TGGATGGTAA AAGCTGAGAC ATTCCATTTT GTTTTTGGTT CATTCAAGCT AGAACGTTCT 
GCACCAAAGC CCCGACTTGA ACACCAGAAA AAAGTTCGCA AGATGGAAGA AAATGGCAAC 
ATGCCTACAA AGTTGCAGAA GTTGGACCTG AGTAGTTATC CAGAAGCGAC AGAAAAAAAC 
GTAGAAAGGA TTTTGGGATT GTTGCAAACC TACTTTCGAA AGTATCCTGA TACTCCTGTG 
TCCTATTTTG AGTTTGTGAT TGATCCAAAC TCTTTTTCTC GTACTGTGGA GAATATATTT 
TATGTTTCTT TTATTGTAAG AGATGGTTTT GCAAGAATAA GGCTTGATGA AGACAGGCTG 
CCAATATTAG AGCCGATGAA TGTTAACCAA ATGGGTGAGG GAAATGATTC CAGTTGCCAT 
GGCAGGAAAC AGGGAGTTAT ATCTTTGACT TTACAGGAGT GGAAAAACAT TGTGGCAGCT 
TTTGAAATTT CTGAGGCTAT GATTACATAC TCCTCATACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EID3 ( NM_001008394.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001008395.1 Homo sapiens EP300 interacting inhibitor of differentiation 3 (EID3), mRNA.

Price & Availability↑

CloneID	OHu55906
Clone ID Related Accession (Same CDS sequence)	NM_001008394.2 , NM_001008394.3
Accession Version	NM_001008394.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	EP300-interacting inhibitor of differentiation 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI461575.1 and BC027612.2. On May 17, 2019 this sequence version replaced NM_001008394.2. ##Evidence-Data-START## Transcript is intronless :: HM005376.1, BC027612.2 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000527879.2/ ENSP00000435619.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAAGATGG ATGTGTCAGT GAGGGCCGCG GGCTGCTCCG ACGACCTCAG CTCTGGGGAG 
GCCGACGTAG ACCCAAAGCT CCTGGAGCTC ACCGCTGACG AGGAGAAGTG CCGCAGCATC 
CGCAGGCAGT ACCGGCAGCT CATGTACTGC GTGCGGCAGA ACCGGGAGGA CATCGTGAGC 
TCGGCGAACA ACTCCTTAAC CGAGGCTCTG GAGGAAGCCA ACGTCCTCTT TGATGGCGTG 
AGCCGAACCA GAGAAGCAGC CCTCGACGCC CGGTTTCTTG TTATGGCTTC TGATTTGGGT 
AAAGAAAAGG CAAAGCAGTT AAACTCAGAT ATGAACTTCT TTAATCAGTT AGCATTTTGT 
GACTTTCTGT TTCTGTTCGT GGGTCTGAAT TGGATGGAAG GCGATCCTGA CAAGTTGAGT 
GATTGTGATG ATAGCATAGC TCTTTCCTTC TGGAAGGCAA TAGAAAAGGA AGCAACATCC 
TGGATGGTAA AAGCTGAGAC ATTCCATTTT GTTTTTGGTT CATTCAAGCT AGAACGTTCT 
GCACCAAAGC CCCGACTTGA ACACCAGAAA AAAGTTCGCA AGATGGAAGA AAATGGCAAC 
ATGCCTACAA AGTTGCAGAA GTTGGACCTG AGTAGTTATC CAGAAGCGAC AGAAAAAAAC 
GTAGAAAGGA TTTTGGGATT GTTGCAAACC TACTTTCGAA AGTATCCTGA TACTCCTGTG 
TCCTATTTTG AGTTTGTGAT TGATCCAAAC TCTTTTTCTC GTACTGTGGA GAATATATTT 
TATGTTTCTT TTATTGTAAG AGATGGTTTT GCAAGAATAA GGCTTGATGA AGACAGGCTG 
CCAATATTAG AGCCGATGAA TGTTAACCAA ATGGGTGAGG GAAATGATTC CAGTTGCCAT 
GGCAGGAAAC AGGGAGTTAT ATCTTTGACT TTACAGGAGT GGAAAAACAT TGTGGCAGCT 
TTTGAAATTT CTGAGGCTAT GATTACATAC TCCTCATACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008395.1
CDS	197..1198
Translation	MKMDVSVRAAGCSDDLSSGEADVDPKLLELTADEEKCRSIRRQYRQLMYCVRQNREDIVSSANNSLTEALEEANVLFDGVSRTREAALDARFLVMASDLGKEKAKQLNSDMNFFNQLAFCDFLFLFVGLNWMEGDPDKLSDCDDSIALSFWKAIEKEATSWMVKAETFHFVFGSFKLERSAPKPRLEHQKKVRKMEENGNMPTKLQKLDLSSYPEATEKNVERILGLLQTYFRKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIVRDGFARIRLDEDRLPILEPMNVNQMGEGNDSSCHGRKQGVISLTLQEWKNIVAAFEISEAMITYSSY

Target ORF information:

RefSeq Version	NM_001008394.3
Organism	Homo sapiens(human)
Definition	Homo sapiens EP300 interacting inhibitor of differentiation 3 (EID3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008394.3

ORF Insert Sequence:

ATGAAGATGG ATGTGTCAGT GAGGGCCGCG GGCTGCTCCG ACGACCTCAG CTCTGGGGAG 
GCCGACGTAG ACCCAAAGCT CCTGGAGCTC ACCGCTGACG AGGAGAAGTG CCGCAGCATC 
CGCAGGCAGT ACCGGCAGCT CATGTACTGC GTGCGGCAGA ACCGGGAGGA CATCGTGAGC 
TCGGCGAACA ACTCCTTAAC CGAGGCTCTG GAGGAAGCCA ACGTCCTCTT TGATGGCGTG 
AGCCGAACCA GAGAAGCAGC CCTCGACGCC CGGTTTCTTG TTATGGCTTC TGATTTGGGT 
AAAGAAAAGG CAAAGCAGTT AAACTCAGAT ATGAACTTCT TTAATCAGTT AGCATTTTGT 
GACTTTCTGT TTCTGTTCGT GGGTCTGAAT TGGATGGAAG GCGATCCTGA CAAGTTGAGT 
GATTGTGATG ATAGCATAGC TCTTTCCTTC TGGAAGGCAA TAGAAAAGGA AGCAACATCC 
TGGATGGTAA AAGCTGAGAC ATTCCATTTT GTTTTTGGTT CATTCAAGCT AGAACGTTCT 
GCACCAAAGC CCCGACTTGA ACACCAGAAA AAAGTTCGCA AGATGGAAGA AAATGGCAAC 
ATGCCTACAA AGTTGCAGAA GTTGGACCTG AGTAGTTATC CAGAAGCGAC AGAAAAAAAC 
GTAGAAAGGA TTTTGGGATT GTTGCAAACC TACTTTCGAA AGTATCCTGA TACTCCTGTG 
TCCTATTTTG AGTTTGTGAT TGATCCAAAC TCTTTTTCTC GTACTGTGGA GAATATATTT 
TATGTTTCTT TTATTGTAAG AGATGGTTTT GCAAGAATAA GGCTTGATGA AGACAGGCTG 
CCAATATTAG AGCCGATGAA TGTTAACCAA ATGGGTGAGG GAAATGATTC CAGTTGCCAT 
GGCAGGAAAC AGGGAGTTAT ATCTTTGACT TTACAGGAGT GGAAAAACAT TGTGGCAGCT 
TTTGAAATTT CTGAGGCTAT GATTACATAC TCCTCATACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

EID3 directly associates with DNMT3A during transdifferentiation of human umbilical cord mesenchymal stem cells to NPC-like cells.
Scientific reports740463(2017 Jan)
Luo L,Chen WJ,Yin JQ,Xu RX

Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
British journal of clinical pharmacology78(2)373-83(2014 Aug)
Ji Y,Schaid DJ,Desta Z,Kubo M,Batzler AJ,Snyder K,Mushiroda T,Kamatani N,Ogburn E,Hall-Flavin D,Flockhart D,Nakamura Y,Mrazek DA,Weinshilboum RM

Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families.
PloS one6(2)e17270(2011 Feb)
Hudson JJ,Bednarova K,Kozakova L,Liao C,Guerineau M,Colnaghi R,Vidot S,Marek J,Bathula SR,Lehmann AR,Palecek J