NPR1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NPR1
Entrez Gene ID	4881
Full Name	natriuretic peptide receptor 1
Synonyms	ANPRA,ANPa,GUC2A,GUCY2A,NPRA
General protein information	Preferred Names natriuretic peptide receptor 1 Names atrial natriuretic peptide receptor 1 ANP-A ANPR-A GC-A NPR-A atrial natriuretic peptide receptor type A atrionatriuretic peptide receptor A guanylate cyclase A natriuretic peptide A type receptor natriuretic peptide receptor A natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) testicular tissue protein Li 20
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q21.3
Summary	Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009].
Disorder MIM:	108960

mRNA and Protein(s)

mRNA	Protein	Name
NM_000906.4	NP_000897.3	atrial natriuretic peptide receptor 1 precursor
XM_017001374.2	XP_016856863.1	atrial natriuretic peptide receptor 1 isoform X2
XM_005245218.1	XP_005245275.1	atrial natriuretic peptide receptor 1 isoform X1
XM_017001374.1	XP_016856863.1	atrial natriuretic peptide receptor 1 isoform X2
NM_000906.3	NP_000897.3	atrial natriuretic peptide receptor 1 precursor
XM_005245218.2	XP_005245275.1	atrial natriuretic peptide receptor 1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NPR1	XP_003308543.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008691	XP_314790.4
Canis lupus familiaris (dog)	NPR1	XP_547577.2
Danio rerio (zebrafish)	npr1a	NP_001038402.1
	NPR1	XP_002808282.1
Mus musculus (house mouse)	Npr1	NP_032753.5
Homo sapiens (human)	NPR1	NP_000897.3
Bos taurus (cattle)	NPR1	NP_001179680.1
Rattus norvegicus (Norway rat)	Npr1	NP_036745.1
Drosophila melanogaster (fruit fly)	CG3216	NP_726013.2

Gene Ontology
Bibliography

Related articles in PubMed

Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction.
Nakagawa M, Naruko T, Sugioka K, Kitabayashi C, Shirai N, Takagi M, Yoshiyama M, Ohsawa M, Ueda M
Molecular medicine reports16(3)3324-3330(2017 Sep)

CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading.
Miura K, Nojiri T, Akitake Y, Ando K, Fukuhara S, Zenitani M, Kimura T, Hino J, Miyazato M, Hosoda H, Kangawa K
The Biochemical journal474(11)1897-1918(2017 05)

Natriuretic peptide receptor A inhibition suppresses gastric cancer development through reactive oxygen species-mediated G2/M cell cycle arrest and cell death.
Li Z, Wang JW, Wang WZ, Zhi XF, Zhang Q, Li BW, Wang LJ, Xie KL, Tao JQ, Tang J, Wei S, Zhu Y, Xu H, Zhang DC, Yang L, Xu ZK
Free radical biology & medicine99593-607(2016 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that signaling via ANP/ANPR (atrial natriuretic factor/ANP receptor) in vascular endothelial cells activates PAK4 (p21-activated kinase 4) and CCM2 (cerebral cavernous malformation 2 protein), resulting in phosphorylation of MLC (myosin light chain), cytoskeletal reorganization, and cell spreading; kinase homology domain of ANPRA (guanylyl cyclase-A) activates downstream targets of ANP/ANPR signaling.
Title: CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading.

The results indicate that the inhibition of NPRA suppresses gastric cancer development and targeting NPRA may represent a promising strategy for the treatment of gastric cancer.
Title: Natriuretic peptide receptor A inhibition suppresses gastric cancer development through reactive oxygen species-mediated G2/M cell cycle arrest and cell death.

Data suggest up-regulation of NPRA in skeletal muscle (SM) correlates with whole-body insulin sensitivity; NPRA is down-regulated in SM in obese subjects compared to normal controls; NPRA in SM is up-regulated in response to diet-induced weight loss.
Title: Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes.

After ligand binding, NPRA is rapidly internalized and trafficked from the cell surface into endosomes, Res and lysosomes, with concurrent generation of intracellular cyclic GMP in HEK-293 cells.
Title: Subcellular trafficking of guanylyl cyclase/natriuretic peptide receptor-A with concurrent generation of intracellular cGMP.

In this review we highlight the mechanisms by which NPR-A affects signaling pathways involved in inflammation and cancer, and we discuss its potential as a novel target in inflammation, cancer, and cancer-related inflammation
Title: NPR-A: A Therapeutic Target in Inflammation and Cancer.

The following NPR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NPR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09254	NM_000906.4 Latest version!	Homo sapiens natriuretic peptide receptor 1 (NPR1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu90065	XM_017001374.2 Latest version!	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu34418	XM_005245218.2 Latest version!	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu90065	XM_017001374.1	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu09254	NM_000906.3	Homo sapiens natriuretic peptide receptor 1 (NPR1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu34418	XM_005245218.1	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NPR1 ( NM_000906.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000897.3 Homo sapiens natriuretic peptide receptor 1 (NPR1), mRNA.

Price & Availability↑

CloneID	OHu09254
Clone ID Related Accession (Same CDS sequence)	NM_000906.4 , NM_000906.3
Accession Version	NM_000906.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3186bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	atrial natriuretic peptide receptor 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK025024.1. On Nov 22, 2018 this sequence version replaced NM_000906.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK025024.1, HM005333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000368680.4/ ENSP00000357669.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CAAAAAGCTG 
TGGACGGCCC CTGAGCTCCT GCGAATGGCT TCACCCCCTG TGCGGGGCTC CCAGGCTGGT 
GACGTATACA GCTTTGGGAT CATCCTTCAG GAGATTGCCC TGAGGAGTGG GGTCTTCCAC 
GTGGAAGGTT TGGACCTGAG CCCCAAAGAG ATCATCGAGC GGGTGACTCG GGGTGAGCAG 
CCCCCCTTCC GGCCCTCCCT GGCCCTGCAG AGTCACCTGG AGGAGTTGGG GCTGCTCATG 
CAGCGGTGCT GGGCTGAGGA CCCACAGGAG AGGCCACCAT TCCAGCAGAT CCGCCTGACG 
TTGCGCAAAT TTAACAGGGA GAACAGCAGC AACATCCTGG ACAACCTGCT GTCCCGCATG 
GAGCAGTACG CGAACAATCT GGAGGAACTG GTGGAGGAGC GGACCCAGGC ATACCTGGAG 
GAGAAGCGCA AGGCTGAGGC CCTGCTCTAC CAGATCCTGC CTCACTCAGT GGCTGAGCAG 
CTGAAGCGTG GGGAGACGGT GCAGGCCGAA GCCTTTGACA GTGTTACCAT CTACTTCAGT 
GACATTGTGG GTTTCACAGC GCTGTCGGCG GAGAGCACAC CCATGCAGGT GGTGACCCTG 
CTCAATGACC TGTACACTTG CTTTGATGCT GTCATAGACA ACTTTGATGT GTACAAGGTG 
GAGACAATTG GCGATGCCTA CATGGTGGTG TCAGGGCTCC CTGTGCGGAA CGGGCGGCTA 
CACGCCTGCG AGGTAGCCCG CATGGCCCTG GCACTGCTGG ATGCTGTGCG CTCCTTCCGA 
ATCCGCCACC GGCCCCAGGA GCAGCTGCGC TTGCGCATTG GCATCCACAC AGGACCTGTG 
TGTGCTGGAG TGGTGGGACT GAAGATGCCC CGTTACTGTC TCTTTGGGGA TACAGTCAAC 
ACAGCCTCAA GAATGGAGTC TAATGGGGAA GCCCTGAAGA TCCACTTGTC TTCTGAGACC 
AAGGCTGTCC TGGAGGAGTT TGGTGGTTTC GAGCTGGAGC TTCGAGGGGA TGTAGAAATG 
AAGGGCAAAG GCAAGGTTCG GACCTACTGG CTCCTTGGGG AGAGGGGGAG TAGCACCCGA 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000897.3
CDS	422..3607
Translation	MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG

Target ORF information:

RefSeq Version	NM_000906.4
Organism	Homo sapiens(human)
Definition	Homo sapiens natriuretic peptide receptor 1 (NPR1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000906.4

ORF Insert Sequence:

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CAAAAAGCTG 
TGGACGGCCC CTGAGCTCCT GCGAATGGCT TCACCCCCTG TGCGGGGCTC CCAGGCTGGT 
GACGTATACA GCTTTGGGAT CATCCTTCAG GAGATTGCCC TGAGGAGTGG GGTCTTCCAC 
GTGGAAGGTT TGGACCTGAG CCCCAAAGAG ATCATCGAGC GGGTGACTCG GGGTGAGCAG 
CCCCCCTTCC GGCCCTCCCT GGCCCTGCAG AGTCACCTGG AGGAGTTGGG GCTGCTCATG 
CAGCGGTGCT GGGCTGAGGA CCCACAGGAG AGGCCACCAT TCCAGCAGAT CCGCCTGACG 
TTGCGCAAAT TTAACAGGGA GAACAGCAGC AACATCCTGG ACAACCTGCT GTCCCGCATG 
GAGCAGTACG CGAACAATCT GGAGGAACTG GTGGAGGAGC GGACCCAGGC ATACCTGGAG 
GAGAAGCGCA AGGCTGAGGC CCTGCTCTAC CAGATCCTGC CTCACTCAGT GGCTGAGCAG 
CTGAAGCGTG GGGAGACGGT GCAGGCCGAA GCCTTTGACA GTGTTACCAT CTACTTCAGT 
GACATTGTGG GTTTCACAGC GCTGTCGGCG GAGAGCACAC CCATGCAGGT GGTGACCCTG 
CTCAATGACC TGTACACTTG CTTTGATGCT GTCATAGACA ACTTTGATGT GTACAAGGTG 
GAGACAATTG GCGATGCCTA CATGGTGGTG TCAGGGCTCC CTGTGCGGAA CGGGCGGCTA 
CACGCCTGCG AGGTAGCCCG CATGGCCCTG GCACTGCTGG ATGCTGTGCG CTCCTTCCGA 
ATCCGCCACC GGCCCCAGGA GCAGCTGCGC TTGCGCATTG GCATCCACAC AGGACCTGTG 
TGTGCTGGAG TGGTGGGACT GAAGATGCCC CGTTACTGTC TCTTTGGGGA TACAGTCAAC 
ACAGCCTCAA GAATGGAGTC TAATGGGGAA GCCCTGAAGA TCCACTTGTC TTCTGAGACC 
AAGGCTGTCC TGGAGGAGTT TGGTGGTTTC GAGCTGGAGC TTCGAGGGGA TGTAGAAATG 
AAGGGCAAAG GCAAGGTTCG GACCTACTGG CTCCTTGGGG AGAGGGGGAG TAGCACCCGA 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NPR1 ( NM_000906.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000897.3 Homo sapiens natriuretic peptide receptor 1 (NPR1), mRNA.

Price & Availability↑

CloneID	OHu09254
Clone ID Related Accession (Same CDS sequence)	NM_000906.4 , NM_000906.3
Accession Version	NM_000906.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3186bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	atrial natriuretic peptide receptor 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK025024.1. On Feb 14, 2008 this sequence version replaced NM_000906.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK025024.1, HM005333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CAAAAAGCTG 
TGGACGGCCC CTGAGCTCCT GCGAATGGCT TCACCCCCTG TGCGGGGCTC CCAGGCTGGT 
GACGTATACA GCTTTGGGAT CATCCTTCAG GAGATTGCCC TGAGGAGTGG GGTCTTCCAC 
GTGGAAGGTT TGGACCTGAG CCCCAAAGAG ATCATCGAGC GGGTGACTCG GGGTGAGCAG 
CCCCCCTTCC GGCCCTCCCT GGCCCTGCAG AGTCACCTGG AGGAGTTGGG GCTGCTCATG 
CAGCGGTGCT GGGCTGAGGA CCCACAGGAG AGGCCACCAT TCCAGCAGAT CCGCCTGACG 
TTGCGCAAAT TTAACAGGGA GAACAGCAGC AACATCCTGG ACAACCTGCT GTCCCGCATG 
GAGCAGTACG CGAACAATCT GGAGGAACTG GTGGAGGAGC GGACCCAGGC ATACCTGGAG 
GAGAAGCGCA AGGCTGAGGC CCTGCTCTAC CAGATCCTGC CTCACTCAGT GGCTGAGCAG 
CTGAAGCGTG GGGAGACGGT GCAGGCCGAA GCCTTTGACA GTGTTACCAT CTACTTCAGT 
GACATTGTGG GTTTCACAGC GCTGTCGGCG GAGAGCACAC CCATGCAGGT GGTGACCCTG 
CTCAATGACC TGTACACTTG CTTTGATGCT GTCATAGACA ACTTTGATGT GTACAAGGTG 
GAGACAATTG GCGATGCCTA CATGGTGGTG TCAGGGCTCC CTGTGCGGAA CGGGCGGCTA 
CACGCCTGCG AGGTAGCCCG CATGGCCCTG GCACTGCTGG ATGCTGTGCG CTCCTTCCGA 
ATCCGCCACC GGCCCCAGGA GCAGCTGCGC TTGCGCATTG GCATCCACAC AGGACCTGTG 
TGTGCTGGAG TGGTGGGACT GAAGATGCCC CGTTACTGTC TCTTTGGGGA TACAGTCAAC 
ACAGCCTCAA GAATGGAGTC TAATGGGGAA GCCCTGAAGA TCCACTTGTC TTCTGAGACC 
AAGGCTGTCC TGGAGGAGTT TGGTGGTTTC GAGCTGGAGC TTCGAGGGGA TGTAGAAATG 
AAGGGCAAAG GCAAGGTTCG GACCTACTGG CTCCTTGGGG AGAGGGGGAG TAGCACCCGA 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000897.3
CDS	422..3607
Translation	MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG

Target ORF information:

RefSeq Version	NM_000906.3
Organism	Homo sapiens(human)
Definition	Homo sapiens natriuretic peptide receptor 1 (NPR1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000906.3

ORF Insert Sequence:

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CAAAAAGCTG 
TGGACGGCCC CTGAGCTCCT GCGAATGGCT TCACCCCCTG TGCGGGGCTC CCAGGCTGGT 
GACGTATACA GCTTTGGGAT CATCCTTCAG GAGATTGCCC TGAGGAGTGG GGTCTTCCAC 
GTGGAAGGTT TGGACCTGAG CCCCAAAGAG ATCATCGAGC GGGTGACTCG GGGTGAGCAG 
CCCCCCTTCC GGCCCTCCCT GGCCCTGCAG AGTCACCTGG AGGAGTTGGG GCTGCTCATG 
CAGCGGTGCT GGGCTGAGGA CCCACAGGAG AGGCCACCAT TCCAGCAGAT CCGCCTGACG 
TTGCGCAAAT TTAACAGGGA GAACAGCAGC AACATCCTGG ACAACCTGCT GTCCCGCATG 
GAGCAGTACG CGAACAATCT GGAGGAACTG GTGGAGGAGC GGACCCAGGC ATACCTGGAG 
GAGAAGCGCA AGGCTGAGGC CCTGCTCTAC CAGATCCTGC CTCACTCAGT GGCTGAGCAG 
CTGAAGCGTG GGGAGACGGT GCAGGCCGAA GCCTTTGACA GTGTTACCAT CTACTTCAGT 
GACATTGTGG GTTTCACAGC GCTGTCGGCG GAGAGCACAC CCATGCAGGT GGTGACCCTG 
CTCAATGACC TGTACACTTG CTTTGATGCT GTCATAGACA ACTTTGATGT GTACAAGGTG 
GAGACAATTG GCGATGCCTA CATGGTGGTG TCAGGGCTCC CTGTGCGGAA CGGGCGGCTA 
CACGCCTGCG AGGTAGCCCG CATGGCCCTG GCACTGCTGG ATGCTGTGCG CTCCTTCCGA 
ATCCGCCACC GGCCCCAGGA GCAGCTGCGC TTGCGCATTG GCATCCACAC AGGACCTGTG 
TGTGCTGGAG TGGTGGGACT GAAGATGCCC CGTTACTGTC TCTTTGGGGA TACAGTCAAC 
ACAGCCTCAA GAATGGAGTC TAATGGGGAA GCCCTGAAGA TCCACTTGTC TTCTGAGACC 
AAGGCTGTCC TGGAGGAGTT TGGTGGTTTC GAGCTGGAGC TTCGAGGGGA TGTAGAAATG 
AAGGGCAAAG GCAAGGTTCG GACCTACTGG CTCCTTGGGG AGAGGGGGAG TAGCACCCGA 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NPR1 ( XM_017001374.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856863.1 Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X2, mRNA.

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CloneID	OHu90065
Clone ID Related Accession (Same CDS sequence)	XM_017001374.2 , XM_017001374.1
Accession Version	XM_017001374.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2115bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	atrial natriuretic peptide receptor 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017001374.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CACTTTGGGC 
TCCCTCACTC GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856863.1
CDS	461..2575
Translation	MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYATLGSLTR

Target ORF information:

RefSeq Version	XM_017001374.2
Organism	Homo sapiens(human)
Definition	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001374.2

ORF Insert Sequence:

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CACTTTGGGC 
TCCCTCACTC GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NPR1 ( XM_017001374.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856863.1 Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu90065
Clone ID Related Accession (Same CDS sequence)	XM_017001374.2 , XM_017001374.1
Accession Version	XM_017001374.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2115bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	atrial natriuretic peptide receptor 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CACTTTGGGC 
TCCCTCACTC GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856863.1
CDS	493..2607
Translation	MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYATLGSLTR

Target ORF information:

RefSeq Version	XM_017001374.1
Organism	Homo sapiens(human)
Definition	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001374.1

ORF Insert Sequence:

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
GGCAACCTCG TGGCTGTGAA ACGTGTGAAC CGTAAACGCA TTGAGCTGAC ACGAAAAGTC 
CTGTTTGAAC TGAAGCATAT GCGGGATGTG CAGAATGAAC ACCTGACCAG GTTTGTGGGA 
GCCTGCACCG ACCCCCCCAA TATCTGCATC CTCACAGAGT ACTGTCCCCG TGGGAGCCTG 
CAGGACATTC TGGAGAATGA GAGCATCACC CTGGACTGGA TGTTCCGGTA CTCACTCACC 
AATGACATCG TCAAGGGCAT GCTGTTTCTA CACAATGGGG CTATCTGTTC CCATGGGAAC 
CTCAAGTCAT CCAACTGCGT GGTAGATGGG CGCTTTGTGC TCAAGATCAC CGACTATGGG 
CTGGAGAGCT TCAGGGACCT GGACCCAGAG CAAGGACACA CCGTTTATGC CACTTTGGGC 
TCCCTCACTC GGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NPR1 ( XM_005245218.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245275.1 Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu34418
Clone ID Related Accession (Same CDS sequence)	XM_005245218.1 , XM_005245218.2
Accession Version	XM_005245218.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3108bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	atrial natriuretic peptide receptor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
ATGCGGGATG TGCAGAATGA ACACCTGACC AGGTTTGTGG GAGCCTGCAC CGACCCCCCC 
AATATCTGCA TCCTCACAGA GTACTGTCCC CGTGGGAGCC TGCAGGACAT TCTGGAGAAT 
GAGAGCATCA CCCTGGACTG GATGTTCCGG TACTCACTCA CCAATGACAT CGTCAAGGGC 
ATGCTGTTTC TACACAATGG GGCTATCTGT TCCCATGGGA ACCTCAAGTC ATCCAACTGC 
GTGGTAGATG GGCGCTTTGT GCTCAAGATC ACCGACTATG GGCTGGAGAG CTTCAGGGAC 
CTGGACCCAG AGCAAGGACA CACCGTTTAT GCCAAAAAGC TGTGGACGGC CCCTGAGCTC 
CTGCGAATGG CTTCACCCCC TGTGCGGGGC TCCCAGGCTG GTGACGTATA CAGCTTTGGG 
ATCATCCTTC AGGAGATTGC CCTGAGGAGT GGGGTCTTCC ACGTGGAAGG TTTGGACCTG 
AGCCCCAAAG AGATCATCGA GCGGGTGACT CGGGGTGAGC AGCCCCCCTT CCGGCCCTCC 
CTGGCCCTGC AGAGTCACCT GGAGGAGTTG GGGCTGCTCA TGCAGCGGTG CTGGGCTGAG 
GACCCACAGG AGAGGCCACC ATTCCAGCAG ATCCGCCTGA CGTTGCGCAA ATTTAACAGG 
GAGAACAGCA GCAACATCCT GGACAACCTG CTGTCCCGCA TGGAGCAGTA CGCGAACAAT 
CTGGAGGAAC TGGTGGAGGA GCGGACCCAG GCATACCTGG AGGAGAAGCG CAAGGCTGAG 
GCCCTGCTCT ACCAGATCCT GCCTCACTCA GTGGCTGAGC AGCTGAAGCG TGGGGAGACG 
GTGCAGGCCG AAGCCTTTGA CAGTGTTACC ATCTACTTCA GTGACATTGT GGGTTTCACA 
GCGCTGTCGG CGGAGAGCAC ACCCATGCAG GTGGTGACCC TGCTCAATGA CCTGTACACT 
TGCTTTGATG CTGTCATAGA CAACTTTGAT GTGTACAAGG TGGAGACAAT TGGCGATGCC 
TACATGGTGG TGTCAGGGCT CCCTGTGCGG AACGGGCGGC TACACGCCTG CGAGGTAGCC 
CGCATGGCCC TGGCACTGCT GGATGCTGTG CGCTCCTTCC GAATCCGCCA CCGGCCCCAG 
GAGCAGCTGC GCTTGCGCAT TGGCATCCAC ACAGGACCTG TGTGTGCTGG AGTGGTGGGA 
CTGAAGATGC CCCGTTACTG TCTCTTTGGG GATACAGTCA ACACAGCCTC AAGAATGGAG 
TCTAATGGGG AAGCCCTGAA GATCCACTTG TCTTCTGAGA CCAAGGCTGT CCTGGAGGAG 
TTTGGTGGTT TCGAGCTGGA GCTTCGAGGG GATGTAGAAA TGAAGGGCAA AGGCAAGGTT 
CGGACCTACT GGCTCCTTGG GGAGAGGGGG AGTAGCACCC GAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245275.1
CDS	493..3600
Translation	MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG

Target ORF information:

RefSeq Version	XM_005245218.1
Organism	Homo sapiens(human)
Definition	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245218.1

ORF Insert Sequence:

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
ATGCGGGATG TGCAGAATGA ACACCTGACC AGGTTTGTGG GAGCCTGCAC CGACCCCCCC 
AATATCTGCA TCCTCACAGA GTACTGTCCC CGTGGGAGCC TGCAGGACAT TCTGGAGAAT 
GAGAGCATCA CCCTGGACTG GATGTTCCGG TACTCACTCA CCAATGACAT CGTCAAGGGC 
ATGCTGTTTC TACACAATGG GGCTATCTGT TCCCATGGGA ACCTCAAGTC ATCCAACTGC 
GTGGTAGATG GGCGCTTTGT GCTCAAGATC ACCGACTATG GGCTGGAGAG CTTCAGGGAC 
CTGGACCCAG AGCAAGGACA CACCGTTTAT GCCAAAAAGC TGTGGACGGC CCCTGAGCTC 
CTGCGAATGG CTTCACCCCC TGTGCGGGGC TCCCAGGCTG GTGACGTATA CAGCTTTGGG 
ATCATCCTTC AGGAGATTGC CCTGAGGAGT GGGGTCTTCC ACGTGGAAGG TTTGGACCTG 
AGCCCCAAAG AGATCATCGA GCGGGTGACT CGGGGTGAGC AGCCCCCCTT CCGGCCCTCC 
CTGGCCCTGC AGAGTCACCT GGAGGAGTTG GGGCTGCTCA TGCAGCGGTG CTGGGCTGAG 
GACCCACAGG AGAGGCCACC ATTCCAGCAG ATCCGCCTGA CGTTGCGCAA ATTTAACAGG 
GAGAACAGCA GCAACATCCT GGACAACCTG CTGTCCCGCA TGGAGCAGTA CGCGAACAAT 
CTGGAGGAAC TGGTGGAGGA GCGGACCCAG GCATACCTGG AGGAGAAGCG CAAGGCTGAG 
GCCCTGCTCT ACCAGATCCT GCCTCACTCA GTGGCTGAGC AGCTGAAGCG TGGGGAGACG 
GTGCAGGCCG AAGCCTTTGA CAGTGTTACC ATCTACTTCA GTGACATTGT GGGTTTCACA 
GCGCTGTCGG CGGAGAGCAC ACCCATGCAG GTGGTGACCC TGCTCAATGA CCTGTACACT 
TGCTTTGATG CTGTCATAGA CAACTTTGAT GTGTACAAGG TGGAGACAAT TGGCGATGCC 
TACATGGTGG TGTCAGGGCT CCCTGTGCGG AACGGGCGGC TACACGCCTG CGAGGTAGCC 
CGCATGGCCC TGGCACTGCT GGATGCTGTG CGCTCCTTCC GAATCCGCCA CCGGCCCCAG 
GAGCAGCTGC GCTTGCGCAT TGGCATCCAC ACAGGACCTG TGTGTGCTGG AGTGGTGGGA 
CTGAAGATGC CCCGTTACTG TCTCTTTGGG GATACAGTCA ACACAGCCTC AAGAATGGAG 
TCTAATGGGG AAGCCCTGAA GATCCACTTG TCTTCTGAGA CCAAGGCTGT CCTGGAGGAG 
TTTGGTGGTT TCGAGCTGGA GCTTCGAGGG GATGTAGAAA TGAAGGGCAA AGGCAAGGTT 
CGGACCTACT GGCTCCTTGG GGAGAGGGGG AGTAGCACCC GAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NPR1 ( XM_005245218.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245275.1 Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu34418
Clone ID Related Accession (Same CDS sequence)	XM_005245218.1 , XM_005245218.2
Accession Version	XM_005245218.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3108bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	atrial natriuretic peptide receptor 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005245218.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
ATGCGGGATG TGCAGAATGA ACACCTGACC AGGTTTGTGG GAGCCTGCAC CGACCCCCCC 
AATATCTGCA TCCTCACAGA GTACTGTCCC CGTGGGAGCC TGCAGGACAT TCTGGAGAAT 
GAGAGCATCA CCCTGGACTG GATGTTCCGG TACTCACTCA CCAATGACAT CGTCAAGGGC 
ATGCTGTTTC TACACAATGG GGCTATCTGT TCCCATGGGA ACCTCAAGTC ATCCAACTGC 
GTGGTAGATG GGCGCTTTGT GCTCAAGATC ACCGACTATG GGCTGGAGAG CTTCAGGGAC 
CTGGACCCAG AGCAAGGACA CACCGTTTAT GCCAAAAAGC TGTGGACGGC CCCTGAGCTC 
CTGCGAATGG CTTCACCCCC TGTGCGGGGC TCCCAGGCTG GTGACGTATA CAGCTTTGGG 
ATCATCCTTC AGGAGATTGC CCTGAGGAGT GGGGTCTTCC ACGTGGAAGG TTTGGACCTG 
AGCCCCAAAG AGATCATCGA GCGGGTGACT CGGGGTGAGC AGCCCCCCTT CCGGCCCTCC 
CTGGCCCTGC AGAGTCACCT GGAGGAGTTG GGGCTGCTCA TGCAGCGGTG CTGGGCTGAG 
GACCCACAGG AGAGGCCACC ATTCCAGCAG ATCCGCCTGA CGTTGCGCAA ATTTAACAGG 
GAGAACAGCA GCAACATCCT GGACAACCTG CTGTCCCGCA TGGAGCAGTA CGCGAACAAT 
CTGGAGGAAC TGGTGGAGGA GCGGACCCAG GCATACCTGG AGGAGAAGCG CAAGGCTGAG 
GCCCTGCTCT ACCAGATCCT GCCTCACTCA GTGGCTGAGC AGCTGAAGCG TGGGGAGACG 
GTGCAGGCCG AAGCCTTTGA CAGTGTTACC ATCTACTTCA GTGACATTGT GGGTTTCACA 
GCGCTGTCGG CGGAGAGCAC ACCCATGCAG GTGGTGACCC TGCTCAATGA CCTGTACACT 
TGCTTTGATG CTGTCATAGA CAACTTTGAT GTGTACAAGG TGGAGACAAT TGGCGATGCC 
TACATGGTGG TGTCAGGGCT CCCTGTGCGG AACGGGCGGC TACACGCCTG CGAGGTAGCC 
CGCATGGCCC TGGCACTGCT GGATGCTGTG CGCTCCTTCC GAATCCGCCA CCGGCCCCAG 
GAGCAGCTGC GCTTGCGCAT TGGCATCCAC ACAGGACCTG TGTGTGCTGG AGTGGTGGGA 
CTGAAGATGC CCCGTTACTG TCTCTTTGGG GATACAGTCA ACACAGCCTC AAGAATGGAG 
TCTAATGGGG AAGCCCTGAA GATCCACTTG TCTTCTGAGA CCAAGGCTGT CCTGGAGGAG 
TTTGGTGGTT TCGAGCTGGA GCTTCGAGGG GATGTAGAAA TGAAGGGCAA AGGCAAGGTT 
CGGACCTACT GGCTCCTTGG GGAGAGGGGG AGTAGCACCC GAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245275.1
CDS	461..3568
Translation	MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG

Target ORF information:

RefSeq Version	XM_005245218.2
Organism	Homo sapiens(human)
Definition	Homo sapiens natriuretic peptide receptor 1 (NPR1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245218.2

ORF Insert Sequence:

ATGCCGGGGC CCCGGCGCCC CGCTGGCTCC CGCCTGCGCC TGCTCCTGCT CCTGCTGCTG 
CCGCCGCTGC TGCTGCTGCT CCGGGGCAGC CACGCGGGCA ACCTGACGGT AGCCGTGGTA 
CTGCCGCTGG CCAATACCTC GTACCCCTGG TCGTGGGCGC GCGTGGGACC CGCCGTGGAG 
CTGGCCCTGG CCCAGGTGAA GGCGCGCCCC GACTTGCTGC CGGGCTGGAC GGTCCGCACG 
GTGCTGGGCA GCAGCGAAAA CGCGCTGGGC GTCTGCTCCG ACACCGCAGC GCCCCTGGCC 
GCGGTGGACC TCAAGTGGGA GCACAACCCC GCTGTGTTCC TGGGCCCCGG CTGCGTGTAC 
GCCGCCGCCC CAGTGGGGCG CTTCACCGCG CACTGGCGGG TCCCGCTGCT GACCGCCGGC 
GCCCCGGCGC TGGGCTTCGG TGTCAAGGAC GAGTATGCGC TGACCACCCG CGCGGGGCCC 
AGCTACGCCA AGCTGGGGGA CTTCGTGGCG GCGCTGCACC GACGGCTGGG CTGGGAGCGC 
CAAGCGCTCA TGCTCTACGC CTACCGGCCG GGTGACGAAG AGCACTGCTT CTTCCTCGTG 
GAGGGGCTGT TCATGCGGGT CCGCGACCGC CTCAATATTA CGGTGGACCA CCTGGAGTTC 
GCCGAGGACG ACCTCAGCCA CTACACCAGG CTGCTGCGGA CCATGCCGCG CAAAGGCCGA 
GTTATCTACA TCTGCAGCTC CCCTGATGCC TTCAGAACCC TCATGCTCCT GGCCCTGGAA 
GCTGGCTTGT GTGGGGAGGA CTACGTTTTC TTCCACCTGG ATATCTTTGG GCAAAGCCTG 
CAAGGTGGAC AGGGCCCTGC TCCCCGCAGG CCCTGGGAGA GAGGGGATGG GCAGGATGTC 
AGTGCCCGCC AGGCCTTTCA GGCTGCCAAA ATCATTACAT ATAAAGACCC AGATAATCCC 
GAGTACTTGG AATTCCTGAA GCAGTTAAAA CACCTGGCCT ATGAGCAGTT CAACTTCACC 
ATGGAGGATG GCCTGGTGAA CACCATCCCA GCATCCTTCC ACGACGGGCT CCTGCTCTAT 
ATCCAGGCAG TGACGGAGAC TCTGGCACAT GGGGGAACTG TTACTGATGG GGAGAACATC 
ACTCAGCGGA TGTGGAACCG AAGCTTTCAA GGTGTGACAG GATACCTGAA AATTGATAGC 
AGTGGCGATC GGGAAACAGA CTTCTCCCTC TGGGATATGG ATCCCGAGAA TGGTGCCTTC 
AGGGTTGTAC TGAACTACAA TGGGACTTCC CAAGAGCTGG TGGCTGTGTC GGGGCGCAAA 
CTGAACTGGC CCCTGGGGTA CCCTCCTCCT GACATCCCCA AATGTGGCTT TGACAACGAA 
GACCCAGCAT GCAACCAAGA TCACCTTTCC ACCCTGGAGG TGCTGGCTTT GGTGGGCAGC 
CTCTCCTTGC TCGGCATTCT GATTGTCTCC TTCTTCATAT ACAGGAAGAT GCAGCTGGAG 
AAGGAACTGG CCTCGGAGCT GTGGCGGGTG CGCTGGGAGG ACGTTGAGCC CAGTAGCCTT 
GAGAGGCACC TGCGGAGTGC AGGCAGCCGG CTGACCCTGA GCGGGAGAGG CTCCAATTAC 
GGCTCCCTGC TAACCACAGA GGGCCAGTTC CAAGTCTTTG CCAAGACAGC ATATTATAAG 
ATGCGGGATG TGCAGAATGA ACACCTGACC AGGTTTGTGG GAGCCTGCAC CGACCCCCCC 
AATATCTGCA TCCTCACAGA GTACTGTCCC CGTGGGAGCC TGCAGGACAT TCTGGAGAAT 
GAGAGCATCA CCCTGGACTG GATGTTCCGG TACTCACTCA CCAATGACAT CGTCAAGGGC 
ATGCTGTTTC TACACAATGG GGCTATCTGT TCCCATGGGA ACCTCAAGTC ATCCAACTGC 
GTGGTAGATG GGCGCTTTGT GCTCAAGATC ACCGACTATG GGCTGGAGAG CTTCAGGGAC 
CTGGACCCAG AGCAAGGACA CACCGTTTAT GCCAAAAAGC TGTGGACGGC CCCTGAGCTC 
CTGCGAATGG CTTCACCCCC TGTGCGGGGC TCCCAGGCTG GTGACGTATA CAGCTTTGGG 
ATCATCCTTC AGGAGATTGC CCTGAGGAGT GGGGTCTTCC ACGTGGAAGG TTTGGACCTG 
AGCCCCAAAG AGATCATCGA GCGGGTGACT CGGGGTGAGC AGCCCCCCTT CCGGCCCTCC 
CTGGCCCTGC AGAGTCACCT GGAGGAGTTG GGGCTGCTCA TGCAGCGGTG CTGGGCTGAG 
GACCCACAGG AGAGGCCACC ATTCCAGCAG ATCCGCCTGA CGTTGCGCAA ATTTAACAGG 
GAGAACAGCA GCAACATCCT GGACAACCTG CTGTCCCGCA TGGAGCAGTA CGCGAACAAT 
CTGGAGGAAC TGGTGGAGGA GCGGACCCAG GCATACCTGG AGGAGAAGCG CAAGGCTGAG 
GCCCTGCTCT ACCAGATCCT GCCTCACTCA GTGGCTGAGC AGCTGAAGCG TGGGGAGACG 
GTGCAGGCCG AAGCCTTTGA CAGTGTTACC ATCTACTTCA GTGACATTGT GGGTTTCACA 
GCGCTGTCGG CGGAGAGCAC ACCCATGCAG GTGGTGACCC TGCTCAATGA CCTGTACACT 
TGCTTTGATG CTGTCATAGA CAACTTTGAT GTGTACAAGG TGGAGACAAT TGGCGATGCC 
TACATGGTGG TGTCAGGGCT CCCTGTGCGG AACGGGCGGC TACACGCCTG CGAGGTAGCC 
CGCATGGCCC TGGCACTGCT GGATGCTGTG CGCTCCTTCC GAATCCGCCA CCGGCCCCAG 
GAGCAGCTGC GCTTGCGCAT TGGCATCCAC ACAGGACCTG TGTGTGCTGG AGTGGTGGGA 
CTGAAGATGC CCCGTTACTG TCTCTTTGGG GATACAGTCA ACACAGCCTC AAGAATGGAG 
TCTAATGGGG AAGCCCTGAA GATCCACTTG TCTTCTGAGA CCAAGGCTGT CCTGGAGGAG 
TTTGGTGGTT TCGAGCTGGA GCTTCGAGGG GATGTAGAAA TGAAGGGCAA AGGCAAGGTT 
CGGACCTACT GGCTCCTTGG GGAGAGGGGG AGTAGCACCC GAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction.
Molecular medicine reports16(3)3324-3330(2017 Sep)
Nakagawa M,Naruko T,Sugioka K,Kitabayashi C,Shirai N,Takagi M,Yoshiyama M,Ohsawa M,Ueda M

CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading.
The Biochemical journal474(11)1897-1918(2017 05)
Miura K,Nojiri T,Akitake Y,Ando K,Fukuhara S,Zenitani M,Kimura T,Hino J,Miyazato M,Hosoda H,Kangawa K

Natriuretic peptide receptor A inhibition suppresses gastric cancer development through reactive oxygen species-mediated G2/M cell cycle arrest and cell death.
Free radical biology & medicine99593-607(2016 10)
Li Z,Wang JW,Wang WZ,Zhi XF,Zhang Q,Li BW,Wang LJ,Xie KL,Tao JQ,Tang J,Wei S,Zhu Y,Xu H,Zhang DC,Yang L,Xu ZK

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NPR1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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