Gene Symbol | NQO2 |
Entrez Gene ID | 4835 |
Full Name | N-ribosyldihydronicotinamide:quinone reductase 2 |
Synonyms | DHQV,DIA6,NMOR2,QR2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(Human) |
Genome | |
Summary | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]. |
Disorder MIM: | |
Disorder Html: | {?Breast cancer susceptibility}, 114480 (1) |