NINJ2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NINJ2
Entrez Gene ID	4815
Full Name	ninjurin 2
General protein information	Preferred Names ninjurin 2 Names ninjurin-2 nerve injury-induced protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.33
Summary	The protein encoded by this gene belongs to the ninjurin (for nerve injury induced) family. It is a cell surface adhesion protein that is upregulated in Schwann cells surrounding the distal segment of injured nerve, and promotes neurite outgrowth, thus may have a role in nerve regeneration after nerve injury. [provided by RefSeq, Oct 2011].
Disorder MIM:	607297

mRNA and Protein(s)

mRNA	Protein	Name
NM_016533.5	NP_057617.2	ninjurin-2 isoform 1
NM_001294345.2	NP_001281274.1	ninjurin-2 isoform 2
NM_016533.6	NP_057617.3	ninjurin-2 isoform 1
NM_001294345.1	NP_001281274.1	ninjurin-2 isoform 2
NM_001294346.1	NP_001281275.1	ninjurin-2 isoform 3
NM_001367996.1	NP_001354925.1	ninjurin-2 isoform 3
NM_001294346.2	NP_001281275.1	ninjurin-2 isoform 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ninj2	NP_057927.1
Homo sapiens (human)	NINJ2	NP_057617.2
Canis lupus familiaris (dog)	NINJ2	XP_854702.2
Rattus norvegicus (Norway rat)	Ninj2	NP_067606.1
Danio rerio (zebrafish)	ninj2	XP_001339643.2
Gallus gallus (chicken)	NINJ2	XP_416382.3
	NINJ2	XP_001095186.2
Pan troglodytes (chimpanzee)	NINJ2	XP_001149633.1
Xenopus tropicalis (tropical clawed frog)	ninj2	XP_004913180.1

Gene Ontology
Bibliography

Related articles in PubMed

NINJ2- A novel regulator of endothelial inflammation and activation.
Wang J, Fa J, Wang P, Jia X, Peng H, Chen J, Wang Y, Wang C, Chen Q, Tu X, Wang QK, Xu C
Cellular signalling35231-241(2017 Jul)

A Novel Functional Polymorphism in the NINJ2 Promoter Predicts Risk of Large Artery Atherosclerotic Stroke.
Zhang Z, Ni G, Xu G, Xu J, Liu X
Molecular neurobiology53(10)7178-7183(2016 Dec)

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.
Bis JC, DeStefano A, Liu X, Brody JA, Choi SH, Verhaaren BF, Debette S, Ikram MA, Shahar E, Butler KR Jr, Gottesman RF, Muzny D, Kovar CL, Psaty BM, Hofman A, Lumley T, Gupta M, Wolf PA, van Duijn C, Gibbs RA, Mosley TH, Longstreth WT Jr, Boerwinkle E, Seshadri S, Fornage M
PloS one9(6)e99798(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the AA genotype carriers had significantly increased NINJ2 mRNA expression levels in the Chinese population, suggesting that the rs3809263 G > A polymorphism is a functional single nucleotide polymorphism and a biomarker for risk of large artery atherosclerotic stroke.
Title: A Novel Functional Polymorphism in the NINJ2 Promoter Predicts Risk of Large Artery Atherosclerotic Stroke.

Risk of ischemic stroke was higher especially when the carriers of rs11833579 AA NINJ2 genotype were smokers.
Title: Association between NINJ2 gene polymorphisms and ischemic stroke: a family-based case-control study.

Data shows that common and rare variants in the NINJ2 region were nominally associated with incident ischemic stroke patients.
Title: Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.

This meta-analysis suggest that rs12425791 is relative to ischemic stroke risk under dominant model in Asian population, but not for rs11833579.
Title: The rs11833579 and rs12425791 polymorphisms and risk of ischemic stroke in an Asian population: a meta-analysis.

Data suggest that the gene NINJ2 rs11833579 A/A or G/A genotype may bring forward the onset age of first-ever ischemic stroke without increasing silent cerebrovascular lesions prior to the stroke.
Title: NINJ2 SNP may affect the onset age of first-ever ischemic stroke without increasing silent cerebrovascular lesions.

The following NINJ2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NINJ2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28707	NM_001294346.2 Latest version!	Homo sapiens ninjurin 2 (NINJ2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu28707	NM_001367996.1 Latest version!	Homo sapiens ninjurin 2 (NINJ2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu28705	NM_016533.5 Latest version!	Homo sapiens ninjurin 2 (NINJ2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu28706	NM_001294345.2 Latest version!	Homo sapiens ninjurin 2 (NINJ2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu107897	NM_016533.6 Latest version!	Homo sapiens ninjurin 2 (NINJ2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu28706	NM_001294345.1	Homo sapiens ninjurin 2 (NINJ2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu28707	NM_001294346.1	Homo sapiens ninjurin 2 (NINJ2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NINJ2 ( NM_001294346.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001281275.1 Homo sapiens ninjurin 2 (NINJ2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu28707
Clone ID Related Accession (Same CDS sequence)	NM_001294346.1 , NM_001367996.1 , NM_001294346.2
Accession Version	NM_001294346.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-05
Organism	Homo sapiens(human)
Product	ninjurin-2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from R06312.1, CD695373.1 and AF205633.1. Transcript Variant: This variant (3) contains an alternate 5' terminal exon which results in a different 5' UTR and causes translation initiation at a downstream start codon compared to variant 1. The encoded isoform (3) has a shorter N-terminus compared to isoform 1. Variants 3 and 4 both encode the same isoform (3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.254458.1, SRR1163657.323668.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCTGGACG TGGCCCTGTT CATGTCCAAC GCCATGCGGC TGAAGGCGGT GCTGGAGCAG 
GGACCATCCT CTCACTACTA CACCACCCTG GTCACCCTCA TCAGCCTCTC TCTGCTCCTG 
CAGGTGGTCA TCGGTGTCCT GCTCGTGGTC ATTGCACGGC TGAACCTGAA TGAGGTAGAA 
AAGCAGTGGC GACTCAACCA GCTCAACAAC GCAGCCACCA TCTTGGTCTT CTTCACTGTG 
GTCATCAATG TTTTCATTAC AGCCTTCGGG GCACATAAAA CAGGGTTCCT GGCTGCCAGG 
GCCTCAAGGA ATCCTCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001281275.1
CDS	251..571
Translation	MLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL

Target ORF information:

RefSeq Version	NM_001294346.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ninjurin 2 (NINJ2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001294346.1

ORF Insert Sequence:

ATGCTGGACG TGGCCCTGTT CATGTCCAAC GCCATGCGGC TGAAGGCGGT GCTGGAGCAG 
GGACCATCCT CTCACTACTA CACCACCCTG GTCACCCTCA TCAGCCTCTC TCTGCTCCTG 
CAGGTGGTCA TCGGTGTCCT GCTCGTGGTC ATTGCACGGC TGAACCTGAA TGAGGTAGAA 
AAGCAGTGGC GACTCAACCA GCTCAACAAC GCAGCCACCA TCTTGGTCTT CTTCACTGTG 
GTCATCAATG TTTTCATTAC AGCCTTCGGG GCACATAAAA CAGGGTTCCT GGCTGCCAGG 
GCCTCAAGGA ATCCTCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NINJ2 ( NM_001367996.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001354925.1 Homo sapiens ninjurin 2 (NINJ2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu28707
Clone ID Related Accession (Same CDS sequence)	NM_001294346.1 , NM_001367996.1 , NM_001294346.2
Accession Version	NM_001367996.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	ninjurin-2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021054.28 and AC006205.9. Transcript Variant: This variant (4), as well as variant 3, encodes isoform 3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.31461.1, SRR1163658.158812.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCTGGACG TGGCCCTGTT CATGTCCAAC GCCATGCGGC TGAAGGCGGT GCTGGAGCAG 
GGACCATCCT CTCACTACTA CACCACCCTG GTCACCCTCA TCAGCCTCTC TCTGCTCCTG 
CAGGTGGTCA TCGGTGTCCT GCTCGTGGTC ATTGCACGGC TGAACCTGAA TGAGGTAGAA 
AAGCAGTGGC GACTCAACCA GCTCAACAAC GCAGCCACCA TCTTGGTCTT CTTCACTGTG 
GTCATCAATG TTTTCATTAC AGCCTTCGGG GCACATAAAA CAGGGTTCCT GGCTGCCAGG 
GCCTCAAGGA ATCCTCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001354925.1
CDS	333..653
Translation	MLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL

Target ORF information:

RefSeq Version	NM_001367996.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ninjurin 2 (NINJ2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001367996.1

ORF Insert Sequence:

ATGCTGGACG TGGCCCTGTT CATGTCCAAC GCCATGCGGC TGAAGGCGGT GCTGGAGCAG 
GGACCATCCT CTCACTACTA CACCACCCTG GTCACCCTCA TCAGCCTCTC TCTGCTCCTG 
CAGGTGGTCA TCGGTGTCCT GCTCGTGGTC ATTGCACGGC TGAACCTGAA TGAGGTAGAA 
AAGCAGTGGC GACTCAACCA GCTCAACAAC GCAGCCACCA TCTTGGTCTT CTTCACTGTG 
GTCATCAATG TTTTCATTAC AGCCTTCGGG GCACATAAAA CAGGGTTCCT GGCTGCCAGG 
GCCTCAAGGA ATCCTCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NINJ2 ( NM_001294346.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001281275.1 Homo sapiens ninjurin 2 (NINJ2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu28707
Clone ID Related Accession (Same CDS sequence)	NM_001294346.1 , NM_001367996.1 , NM_001294346.2
Accession Version	NM_001294346.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Homo sapiens(human)
Product	ninjurin-2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from R06312.1, CD695373.1 and AF205633.1. On Jun 2, 2019 this sequence version replaced NM_001294346.1. Transcript Variant: This variant (3) contains an alternate 5' terminal exon which results in a different 5' UTR and causes translation initiation at a downstream start codon compared to variant 1. The encoded isoform (3) has a shorter N-terminus compared to isoform 1. Variants 3 and 4 both encode the same isoform (3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.254458.1, SRR1163657.430710.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147975 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGGACG TGGCCCTGTT CATGTCCAAC GCCATGCGGC TGAAGGCGGT GCTGGAGCAG 
GGACCATCCT CTCACTACTA CACCACCCTG GTCACCCTCA TCAGCCTCTC TCTGCTCCTG 
CAGGTGGTCA TCGGTGTCCT GCTCGTGGTC ATTGCACGGC TGAACCTGAA TGAGGTAGAA 
AAGCAGTGGC GACTCAACCA GCTCAACAAC GCAGCCACCA TCTTGGTCTT CTTCACTGTG 
GTCATCAATG TTTTCATTAC AGCCTTCGGG GCACATAAAA CAGGGTTCCT GGCTGCCAGG 
GCCTCAAGGA ATCCTCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001281275.1
CDS	202..522
Translation	MLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL

Target ORF information:

RefSeq Version	NM_001294346.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ninjurin 2 (NINJ2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001294346.2

ORF Insert Sequence:

ATGCTGGACG TGGCCCTGTT CATGTCCAAC GCCATGCGGC TGAAGGCGGT GCTGGAGCAG 
GGACCATCCT CTCACTACTA CACCACCCTG GTCACCCTCA TCAGCCTCTC TCTGCTCCTG 
CAGGTGGTCA TCGGTGTCCT GCTCGTGGTC ATTGCACGGC TGAACCTGAA TGAGGTAGAA 
AAGCAGTGGC GACTCAACCA GCTCAACAAC GCAGCCACCA TCTTGGTCTT CTTCACTGTG 
GTCATCAATG TTTTCATTAC AGCCTTCGGG GCACATAAAA CAGGGTTCCT GGCTGCCAGG 
GCCTCAAGGA ATCCTCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NINJ2 ( NM_016533.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_057617.2 Homo sapiens ninjurin 2 (NINJ2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28705
Clone ID Related Accession (Same CDS sequence)	NM_016533.5
Accession Version	NM_016533.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	ninjurin-2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK296012.1, BI597990.1 and AF205633.1. On Jul 1, 2014 this sequence version replaced NM_016533.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.130396.1, SRR1803614.352708.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGGTC TGTCCCGCCA GCTGTGTGCT CTCTCCCACC CGAAGAAAGC AGCAGAGACT 
CAGACGGCGG AGCCTGGAGG AGCCCACGCA GTCTGTTCCC GGCACCCGGT GCGTGTGAAG 
GGACTTGAGG GCAGCGAGAT GGAATCAGCA AGAGAAAACA TCGACCTTCA ACCTGGAAGC 
TCCGACCCCA GGAGCCAGCC CATCAACCTG AACCATTACG CCACCAAGAA GAGCGTGGCG 
GAGAGCATGC TGGACGTGGC CCTGTTCATG TCCAACGCCA TGCGGCTGAA GGCGGTGCTG 
GAGCAGGGAC CATCCTCTCA CTACTACACC ACCCTGGTCA CCCTCATCAG CCTCTCTCTG 
CTCCTGCAGG TGGTCATCGG TGTCCTGCTC GTGGTCATTG CACGGCTGAA CCTGAATGAG 
GTAGAAAAGC AGTGGCGACT CAACCAGCTC AACAACGCAG CCACCATCTT GGTCTTCTTC 
ACTGTGGTCA TCAATGTTTT CATTACAGCC TTCGGGGCAC ATAAAACAGG GTTCCTGGCT 
GCCAGGGCCT CAAGGAATCC TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057617.2
CDS	244..810
Translation	MAGLSRQLCALSHPKKAAETQTAEPGGAHAVCSRHPVRVKGLEGSEMESARENIDLQPGSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL

Target ORF information:

RefSeq Version	NM_016533.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ninjurin 2 (NINJ2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016533.5

ORF Insert Sequence:

ATGGCAGGTC TGTCCCGCCA GCTGTGTGCT CTCTCCCACC CGAAGAAAGC AGCAGAGACT 
CAGACGGCGG AGCCTGGAGG AGCCCACGCA GTCTGTTCCC GGCACCCGGT GCGTGTGAAG 
GGACTTGAGG GCAGCGAGAT GGAATCAGCA AGAGAAAACA TCGACCTTCA ACCTGGAAGC 
TCCGACCCCA GGAGCCAGCC CATCAACCTG AACCATTACG CCACCAAGAA GAGCGTGGCG 
GAGAGCATGC TGGACGTGGC CCTGTTCATG TCCAACGCCA TGCGGCTGAA GGCGGTGCTG 
GAGCAGGGAC CATCCTCTCA CTACTACACC ACCCTGGTCA CCCTCATCAG CCTCTCTCTG 
CTCCTGCAGG TGGTCATCGG TGTCCTGCTC GTGGTCATTG CACGGCTGAA CCTGAATGAG 
GTAGAAAAGC AGTGGCGACT CAACCAGCTC AACAACGCAG CCACCATCTT GGTCTTCTTC 
ACTGTGGTCA TCAATGTTTT CATTACAGCC TTCGGGGCAC ATAAAACAGG GTTCCTGGCT 
GCCAGGGCCT CAAGGAATCC TCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NINJ2 ( NM_001294345.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001281274.1 Homo sapiens ninjurin 2 (NINJ2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28706
Clone ID Related Accession (Same CDS sequence)	NM_001294345.2 , NM_001294345.1
Accession Version	NM_001294345.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	ninjurin-2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC006205.9, CB995632.1, BM128205.1 and AF205633.1. On Jun 2, 2019 this sequence version replaced NM_001294345.1. Transcript Variant: This variant (2) contains an alternate 5' terminal exon which results in a different 5' UTR and causes translation initiation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus, and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.433530.1, SRR5189652.30231.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTATA TGCCTGGAAG CTCCGACCCC AGGAGCCAGC CCATCAACCT GAACCATTAC 
GCCACCAAGA AGAGCGTGGC GGAGAGCATG CTGGACGTGG CCCTGTTCAT GTCCAACGCC 
ATGCGGCTGA AGGCGGTGCT GGAGCAGGGA CCATCCTCTC ACTACTACAC CACCCTGGTC 
ACCCTCATCA GCCTCTCTCT GCTCCTGCAG GTGGTCATCG GTGTCCTGCT CGTGGTCATT 
GCACGGCTGA ACCTGAATGA GGTAGAAAAG CAGTGGCGAC TCAACCAGCT CAACAACGCA 
GCCACCATCT TGGTCTTCTT CACTGTGGTC ATCAATGTTT TCATTACAGC CTTCGGGGCA 
CATAAAACAG GGTTCCTGGC TGCCAGGGCC TCAAGGAATC CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001281274.1
CDS	60..467
Translation	MMYMPGSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL

Target ORF information:

RefSeq Version	NM_001294345.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ninjurin 2 (NINJ2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001294345.2

ORF Insert Sequence:

ATGATGTATA TGCCTGGAAG CTCCGACCCC AGGAGCCAGC CCATCAACCT GAACCATTAC 
GCCACCAAGA AGAGCGTGGC GGAGAGCATG CTGGACGTGG CCCTGTTCAT GTCCAACGCC 
ATGCGGCTGA AGGCGGTGCT GGAGCAGGGA CCATCCTCTC ACTACTACAC CACCCTGGTC 
ACCCTCATCA GCCTCTCTCT GCTCCTGCAG GTGGTCATCG GTGTCCTGCT CGTGGTCATT 
GCACGGCTGA ACCTGAATGA GGTAGAAAAG CAGTGGCGAC TCAACCAGCT CAACAACGCA 
GCCACCATCT TGGTCTTCTT CACTGTGGTC ATCAATGTTT TCATTACAGC CTTCGGGGCA 
CATAAAACAG GGTTCCTGGC TGCCAGGGCC TCAAGGAATC CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NINJ2 ( NM_001294345.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001281274.1 Homo sapiens ninjurin 2 (NINJ2), transcript variant 2, mRNA.

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CloneID	OHu28706
Clone ID Related Accession (Same CDS sequence)	NM_001294345.2 , NM_001294345.1
Accession Version	NM_001294345.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	ninjurin-2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB995632.1, BM128205.1, AC006205.9 and AF205633.1. On Jul 1, 2014 this sequence version replaced XM_005253689.2. Transcript Variant: This variant (2) contains an alternate 5' terminal exon which results in a different 5' UTR and causes translation initiation at an alternate start codon compared to variant 1. The encoded isoform (2) has a distinct N-terminus, and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.358441.1, SRR1163658.245168.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTATA TGCCTGGAAG CTCCGACCCC AGGAGCCAGC CCATCAACCT GAACCATTAC 
GCCACCAAGA AGAGCGTGGC GGAGAGCATG CTGGACGTGG CCCTGTTCAT GTCCAACGCC 
ATGCGGCTGA AGGCGGTGCT GGAGCAGGGA CCATCCTCTC ACTACTACAC CACCCTGGTC 
ACCCTCATCA GCCTCTCTCT GCTCCTGCAG GTGGTCATCG GTGTCCTGCT CGTGGTCATT 
GCACGGCTGA ACCTGAATGA GGTAGAAAAG CAGTGGCGAC TCAACCAGCT CAACAACGCA 
GCCACCATCT TGGTCTTCTT CACTGTGGTC ATCAATGTTT TCATTACAGC CTTCGGGGCA 
CATAAAACAG GGTTCCTGGC TGCCAGGGCC TCAAGGAATC CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001281274.1
CDS	57..464
Translation	MMYMPGSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL

Target ORF information:

RefSeq Version	NM_001294345.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ninjurin 2 (NINJ2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001294345.1

ORF Insert Sequence:

ATGATGTATA TGCCTGGAAG CTCCGACCCC AGGAGCCAGC CCATCAACCT GAACCATTAC 
GCCACCAAGA AGAGCGTGGC GGAGAGCATG CTGGACGTGG CCCTGTTCAT GTCCAACGCC 
ATGCGGCTGA AGGCGGTGCT GGAGCAGGGA CCATCCTCTC ACTACTACAC CACCCTGGTC 
ACCCTCATCA GCCTCTCTCT GCTCCTGCAG GTGGTCATCG GTGTCCTGCT CGTGGTCATT 
GCACGGCTGA ACCTGAATGA GGTAGAAAAG CAGTGGCGAC TCAACCAGCT CAACAACGCA 
GCCACCATCT TGGTCTTCTT CACTGTGGTC ATCAATGTTT TCATTACAGC CTTCGGGGCA 
CATAAAACAG GGTTCCTGGC TGCCAGGGCC TCAAGGAATC CTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NINJ2 ( NM_016533.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_057617.3 Homo sapiens ninjurin 2 (NINJ2), transcript variant 1, mRNA.

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CloneID	OHu107897
Clone ID Related Accession (Same CDS sequence)	NM_016533.6
Accession Version	NM_016533.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	ninjurin-2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021054.28, AF205633.1 and AC006205.9. On Jan 6, 2019 this sequence version replaced NM_016533.5. Transcript Variant: This variant (1) encodes the longest isoform (1). CCDS Note: The coding region has been updated to start at a downstream in-frame start codon that is supported by conservation data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.10988.1, SRR5189652.163921.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAATCAG CAAGAGAAAA CATCGACCTT CAACCTGGAA GCTCCGACCC CAGGAGCCAG 
CCCATCAACC TGAACCATTA CGCCACCAAG AAGAGCGTGG CGGAGAGCAT GCTGGACGTG 
GCCCTGTTCA TGTCCAACGC CATGCGGCTG AAGGCGGTGC TGGAGCAGGG ACCATCCTCT 
CACTACTACA CCACCCTGGT CACCCTCATC AGCCTCTCTC TGCTCCTGCA GGTGGTCATC 
GGTGTCCTGC TCGTGGTCAT TGCACGGCTG AACCTGAATG AGGTAGAAAA GCAGTGGCGA 
CTCAACCAGC TCAACAACGC AGCCACCATC TTGGTCTTCT TCACTGTGGT CATCAATGTT 
TTCATTACAG CCTTCGGGGC ACATAAAACA GGGTTCCTGG CTGCCAGGGC CTCAAGGAAT 
CCTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057617.3
CDS	86..514
Translation	MESARENIDLQPGSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL

Target ORF information:

RefSeq Version	NM_016533.6
Organism	Homo sapiens(human)
Definition	Homo sapiens ninjurin 2 (NINJ2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016533.6

ORF Insert Sequence:

ATGGAATCAG CAAGAGAAAA CATCGACCTT CAACCTGGAA GCTCCGACCC CAGGAGCCAG 
CCCATCAACC TGAACCATTA CGCCACCAAG AAGAGCGTGG CGGAGAGCAT GCTGGACGTG 
GCCCTGTTCA TGTCCAACGC CATGCGGCTG AAGGCGGTGC TGGAGCAGGG ACCATCCTCT 
CACTACTACA CCACCCTGGT CACCCTCATC AGCCTCTCTC TGCTCCTGCA GGTGGTCATC 
GGTGTCCTGC TCGTGGTCAT TGCACGGCTG AACCTGAATG AGGTAGAAAA GCAGTGGCGA 
CTCAACCAGC TCAACAACGC AGCCACCATC TTGGTCTTCT TCACTGTGGT CATCAATGTT 
TTCATTACAG CCTTCGGGGC ACATAAAACA GGGTTCCTGG CTGCCAGGGC CTCAAGGAAT 
CCTCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NINJ2- A novel regulator of endothelial inflammation and activation.
Cellular signalling35231-241(2017 Jul)
Wang J,Fa J,Wang P,Jia X,Peng H,Chen J,Wang Y,Wang C,Chen Q,Tu X,Wang QK,Xu C

A Novel Functional Polymorphism in the NINJ2 Promoter Predicts Risk of Large Artery Atherosclerotic Stroke.
Molecular neurobiology53(10)7178-7183(2016 Dec)
Zhang Z,Ni G,Xu G,Xu J,Liu X

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.
PloS one9(6)e99798(2014)
Bis JC,DeStefano A,Liu X,Brody JA,Choi SH,Verhaaren BF,Debette S,Ikram MA,Shahar E,Butler KR Jr,Gottesman RF,Muzny D,Kovar CL,Psaty BM,Hofman A,Lumley T,Gupta M,Wolf PA,van Duijn C,Gibbs RA,Mosley TH,Longstreth WT Jr,Boerwinkle E,Seshadri S,Fornage M

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NINJ2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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