NFYA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NFYA
Entrez Gene ID	4800
Full Name	nuclear transcription factor Y subunit alpha
Synonyms	CBF-A,CBF-B,HAP2,NF-YA
General protein information	Preferred Names nuclear transcription factor Y subunit alpha Names nuclear transcription factor Y subunit alpha CAAT-box DNA binding protein subunit A CCAAT-binding transcription factor subunit B HAP2 CCAAT-binding protein Transcription factor NF-Y, A subunit nuclear transcription factor Y subunit A nuclear transcription factor Y, alpha
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.1
Summary	The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008].
Disorder MIM:	189903

mRNA and Protein(s)

mRNA	Protein	Name
NM_002505.5	NP_002496.1	nuclear transcription factor Y subunit alpha isoform 1
NM_002505.4	NP_002496.1	nuclear transcription factor Y subunit alpha isoform 1
NM_021705.3	NP_068351.1	nuclear transcription factor Y subunit alpha isoform 2
NM_021705.4	NP_068351.1	nuclear transcription factor Y subunit alpha isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NFYA	XP_005627361.1
Bos taurus (cattle)	NFYA	NP_001014956.1
Danio rerio (zebrafish)	nfyal	NP_001002731.1
Pan troglodytes (chimpanzee)	NFYA	XP_001173997.1
Danio rerio (zebrafish)	nfya	NP_001076264.1
Xenopus tropicalis (tropical clawed frog)	nfya	NP_988933.1
Homo sapiens (human)	NFYA	NP_002496.1
	NFYA	XP_001117262.1
Mus musculus (house mouse)	Nfya	NP_001104302.1
Rattus norvegicus (Norway rat)	Nfya	NP_036997.1
Gallus gallus (chicken)	NFYA	NP_001006325.1

Gene Ontology
Bibliography

Related articles in PubMed

Prognostic role of NF-YA splicing isoforms and Lamin A status in low grade endometrial cancer.
Cicchillitti L, Corrado G, Carosi M, Dabrowska ME, Loria R, Falcioni R, Cutillo G, Piaggio G, Vizza E
Oncotarget8(5)7935-7945(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

increased expression of NF-YA may promote a malignant phenotype in OS cells via modulation of FASN expression.
Title: Transcription factor NF?YA promotes a malignant phenotype by upregulating fatty acid synthase expression.

The findings indicate that overexpression of NF-YA contributes to tumor angiogenesis through EZH2-STAT3 signaling in human melanoma cells, highlighting NF-YA as a potential therapeutic target in human melanoma.
Title: NF-YA promotes invasion and angiogenesis by upregulating EZH2-STAT3 signaling in human melanoma cells.

A direct non-transcriptional role of NF-Y in the overall efficiency of DNA replication, specifically in the DNA elongation process.
Title: Direct non transcriptional role of NF-Y in DNA replication.

our results indicate that NF-YA alternative splicing is an influential muscle cell determinant, through direct regulation of selected cell cycle blocking genes, and, directly and indirectly, of muscle-specific transcription factors
Title: NF-YA splice variants have different roles on muscle differentiation.

Data indicate that specific cancer-driving nodes are generally under NF-YA/B control.
Title: NF-Y activates genes of metabolic pathways altered in cancer cells.

The following NFYA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFYA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09041	NM_002505.5 Latest version!	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu09167	NM_021705.4 Latest version!	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu09041	NM_002505.4	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu09167	NM_021705.3	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NFYA ( NM_002505.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002496.1 Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09041
Clone ID Related Accession (Same CDS sequence)	NM_002505.5 , NM_002505.4
Accession Version	NM_002505.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Homo sapiens(human)
Product	nuclear transcription factor Y subunit alpha isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM561405.1, X59711.1, AL031778.1 and BQ184804.1. On Jun 2, 2019 this sequence version replaced NM_002505.4. Transcript Variant: This variant (1) includes alternate exon B, resulting in the long isoform, isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.158135.1, SRR1803613.251019.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGCAGCA GGGTGGTGTC ACTGCTGTGC AGTTGCAGAC TGAGGCCCAG 
GTGGCATCCG CCTCAGGCCA GCAAGTCCAG ACCCTCCAGG TAGTCCAAGG GCAGCCATTA 
ATGGTGCAGG TCAGTGGAGG CCAGCTAATC ACATCAACTG GCCAACCCAT CATGGTCCAG 
GCTGTCCCTG GTGGACAAGG TCAAACCATC ATGCAAGTAC CTGTTTCTGG AACACAGGGT 
TTGCAGCAAA TACAGTTGGT CCCACCTGGA CAGATCCAGA TCCAGGGTGG ACAGGCTGTG 
CAGGTGCAGG GCCAGCAGGG CCAGACCCAG CAGATCATCA TCCAGCAGCC CCAGACGGCT 
GTCACTGCTG GCCAGACTCA GACACAGCAG CAGATTGCTG TCCAGGGACA GCAAGTGGCA 
CAGACTGCTG AAGGGCAGAC CATCGTCTAT CAACCAGTTA ATGCAGATGG CACCATTCTC 
CAGCAAGTTA CAGTCCCTGT TTCAGGCATG ATCACTATCC CAGCAGCCAG TTTGGCAGGA 
GCACAGATTG TTCAAACAGG AGCCAATACC AACACAACCA GCAGTGGGCA AGGGACTGTC 
ACTGTGACAC TACCAGTGGC AGGCAATGTG GTCAATTCAG GAGGGATGGT CATGATGGTT 
CCTGGGGCTG GCTCTGTGCC TGCTATCCAA AGAATCCCTC TACCTGGAGC AGAGATGCTT 
GAAGAAGAGC CTCTCTACGT GAATGCCAAA CAATACCACC GTATTCTTAA GAGGAGGCAA 
GCCCGAGCTA AACTAGAGGC AGAAGGGAAA ATTCCAAAGG AGAGAAGGAA ATACCTGCAT 
GAGTCTCGGC ACCGTCATGC CATGGCACGG AAGCGTGGTG AAGGTGGACG ATTTTTCTCT 
CCAAAGGAAA AGGATAGTCC CCATATGCAG GATCCAAACC AAGCCGATGA AGAAGCAATG 
ACACAGATCA TCCGAGTGTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002496.1
CDS	173..1216
Translation	MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Target ORF information:

RefSeq Version	NM_002505.5
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002505.5

ORF Insert Sequence:

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGCAGCA GGGTGGTGTC ACTGCTGTGC AGTTGCAGAC TGAGGCCCAG 
GTGGCATCCG CCTCAGGCCA GCAAGTCCAG ACCCTCCAGG TAGTCCAAGG GCAGCCATTA 
ATGGTGCAGG TCAGTGGAGG CCAGCTAATC ACATCAACTG GCCAACCCAT CATGGTCCAG 
GCTGTCCCTG GTGGACAAGG TCAAACCATC ATGCAAGTAC CTGTTTCTGG AACACAGGGT 
TTGCAGCAAA TACAGTTGGT CCCACCTGGA CAGATCCAGA TCCAGGGTGG ACAGGCTGTG 
CAGGTGCAGG GCCAGCAGGG CCAGACCCAG CAGATCATCA TCCAGCAGCC CCAGACGGCT 
GTCACTGCTG GCCAGACTCA GACACAGCAG CAGATTGCTG TCCAGGGACA GCAAGTGGCA 
CAGACTGCTG AAGGGCAGAC CATCGTCTAT CAACCAGTTA ATGCAGATGG CACCATTCTC 
CAGCAAGTTA CAGTCCCTGT TTCAGGCATG ATCACTATCC CAGCAGCCAG TTTGGCAGGA 
GCACAGATTG TTCAAACAGG AGCCAATACC AACACAACCA GCAGTGGGCA AGGGACTGTC 
ACTGTGACAC TACCAGTGGC AGGCAATGTG GTCAATTCAG GAGGGATGGT CATGATGGTT 
CCTGGGGCTG GCTCTGTGCC TGCTATCCAA AGAATCCCTC TACCTGGAGC AGAGATGCTT 
GAAGAAGAGC CTCTCTACGT GAATGCCAAA CAATACCACC GTATTCTTAA GAGGAGGCAA 
GCCCGAGCTA AACTAGAGGC AGAAGGGAAA ATTCCAAAGG AGAGAAGGAA ATACCTGCAT 
GAGTCTCGGC ACCGTCATGC CATGGCACGG AAGCGTGGTG AAGGTGGACG ATTTTTCTCT 
CCAAAGGAAA AGGATAGTCC CCATATGCAG GATCCAAACC AAGCCGATGA AGAAGCAATG 
ACACAGATCA TCCGAGTGTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFYA ( NM_002505.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002496.1 Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09041
Clone ID Related Accession (Same CDS sequence)	NM_002505.5 , NM_002505.4
Accession Version	NM_002505.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	nuclear transcription factor Y subunit alpha isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM561405.1, X59711.1, AL031778.1 and BQ184804.1. On Aug 20, 2008 this sequence version replaced NM_002505.3. Transcript Variant: This variant (1) includes alternate exon B, resulting in the long isoform, isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.53571.1, SRR1803613.251019.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGCAGCA GGGTGGTGTC ACTGCTGTGC AGTTGCAGAC TGAGGCCCAG 
GTGGCATCCG CCTCAGGCCA GCAAGTCCAG ACCCTCCAGG TAGTCCAAGG GCAGCCATTA 
ATGGTGCAGG TCAGTGGAGG CCAGCTAATC ACATCAACTG GCCAACCCAT CATGGTCCAG 
GCTGTCCCTG GTGGACAAGG TCAAACCATC ATGCAAGTAC CTGTTTCTGG AACACAGGGT 
TTGCAGCAAA TACAGTTGGT CCCACCTGGA CAGATCCAGA TCCAGGGTGG ACAGGCTGTG 
CAGGTGCAGG GCCAGCAGGG CCAGACCCAG CAGATCATCA TCCAGCAGCC CCAGACGGCT 
GTCACTGCTG GCCAGACTCA GACACAGCAG CAGATTGCTG TCCAGGGACA GCAAGTGGCA 
CAGACTGCTG AAGGGCAGAC CATCGTCTAT CAACCAGTTA ATGCAGATGG CACCATTCTC 
CAGCAAGTTA CAGTCCCTGT TTCAGGCATG ATCACTATCC CAGCAGCCAG TTTGGCAGGA 
GCACAGATTG TTCAAACAGG AGCCAATACC AACACAACCA GCAGTGGGCA AGGGACTGTC 
ACTGTGACAC TACCAGTGGC AGGCAATGTG GTCAATTCAG GAGGGATGGT CATGATGGTT 
CCTGGGGCTG GCTCTGTGCC TGCTATCCAA AGAATCCCTC TACCTGGAGC AGAGATGCTT 
GAAGAAGAGC CTCTCTACGT GAATGCCAAA CAATACCACC GTATTCTTAA GAGGAGGCAA 
GCCCGAGCTA AACTAGAGGC AGAAGGGAAA ATTCCAAAGG AGAGAAGGAA ATACCTGCAT 
GAGTCTCGGC ACCGTCATGC CATGGCACGG AAGCGTGGTG AAGGTGGACG ATTTTTCTCT 
CCAAAGGAAA AGGATAGTCC CCATATGCAG GATCCAAACC AAGCCGATGA AGAAGCAATG 
ACACAGATCA TCCGAGTGTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002496.1
CDS	179..1222
Translation	MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Target ORF information:

RefSeq Version	NM_002505.4
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002505.4

ORF Insert Sequence:

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGCAGCA GGGTGGTGTC ACTGCTGTGC AGTTGCAGAC TGAGGCCCAG 
GTGGCATCCG CCTCAGGCCA GCAAGTCCAG ACCCTCCAGG TAGTCCAAGG GCAGCCATTA 
ATGGTGCAGG TCAGTGGAGG CCAGCTAATC ACATCAACTG GCCAACCCAT CATGGTCCAG 
GCTGTCCCTG GTGGACAAGG TCAAACCATC ATGCAAGTAC CTGTTTCTGG AACACAGGGT 
TTGCAGCAAA TACAGTTGGT CCCACCTGGA CAGATCCAGA TCCAGGGTGG ACAGGCTGTG 
CAGGTGCAGG GCCAGCAGGG CCAGACCCAG CAGATCATCA TCCAGCAGCC CCAGACGGCT 
GTCACTGCTG GCCAGACTCA GACACAGCAG CAGATTGCTG TCCAGGGACA GCAAGTGGCA 
CAGACTGCTG AAGGGCAGAC CATCGTCTAT CAACCAGTTA ATGCAGATGG CACCATTCTC 
CAGCAAGTTA CAGTCCCTGT TTCAGGCATG ATCACTATCC CAGCAGCCAG TTTGGCAGGA 
GCACAGATTG TTCAAACAGG AGCCAATACC AACACAACCA GCAGTGGGCA AGGGACTGTC 
ACTGTGACAC TACCAGTGGC AGGCAATGTG GTCAATTCAG GAGGGATGGT CATGATGGTT 
CCTGGGGCTG GCTCTGTGCC TGCTATCCAA AGAATCCCTC TACCTGGAGC AGAGATGCTT 
GAAGAAGAGC CTCTCTACGT GAATGCCAAA CAATACCACC GTATTCTTAA GAGGAGGCAA 
GCCCGAGCTA AACTAGAGGC AGAAGGGAAA ATTCCAAAGG AGAGAAGGAA ATACCTGCAT 
GAGTCTCGGC ACCGTCATGC CATGGCACGG AAGCGTGGTG AAGGTGGACG ATTTTTCTCT 
CCAAAGGAAA AGGATAGTCC CCATATGCAG GATCCAAACC AAGCCGATGA AGAAGCAATG 
ACACAGATCA TCCGAGTGTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFYA ( NM_021705.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_068351.1 Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09167
Clone ID Related Accession (Same CDS sequence)	NM_021705.3 , NM_021705.4
Accession Version	NM_021705.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-11
Organism	Homo sapiens(human)
Product	nuclear transcription factor Y subunit alpha isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM561405.1, BC039244.1, AL031778.1 and BQ184804.1. On or before Aug 22, 2008 this sequence version replaced XM_001716589.1, XM_001717592.1, XM_001718396.1, NM_021705.2. Transcript Variant: This variant (2) is missing alternate exon B, resulting in the short isoform, isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.276525.1, SRR1803615.64636.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGGTCCA AGGGCAGCCA TTAATGGTGC AGGTCAGTGG AGGCCAGCTA 
ATCACATCAA CTGGCCAACC CATCATGGTC CAGGCTGTCC CTGGTGGACA AGGTCAAACC 
ATCATGCAAG TACCTGTTTC TGGAACACAG GGTTTGCAGC AAATACAGTT GGTCCCACCT 
GGACAGATCC AGATCCAGGG TGGACAGGCT GTGCAGGTGC AGGGCCAGCA GGGCCAGACC 
CAGCAGATCA TCATCCAGCA GCCCCAGACG GCTGTCACTG CTGGCCAGAC TCAGACACAG 
CAGCAGATTG CTGTCCAGGG ACAGCAAGTG GCACAGACTG CTGAAGGGCA GACCATCGTC 
TATCAACCAG TTAATGCAGA TGGCACCATT CTCCAGCAAG TTACAGTCCC TGTTTCAGGC 
ATGATCACTA TCCCAGCAGC CAGTTTGGCA GGAGCACAGA TTGTTCAAAC AGGAGCCAAT 
ACCAACACAA CCAGCAGTGG GCAAGGGACT GTCACTGTGA CACTACCAGT GGCAGGCAAT 
GTGGTCAATT CAGGAGGGAT GGTCATGATG GTTCCTGGGG CTGGCTCTGT GCCTGCTATC 
CAAAGAATCC CTCTACCTGG AGCAGAGATG CTTGAAGAAG AGCCTCTCTA CGTGAATGCC 
AAACAATACC ACCGTATTCT TAAGAGGAGG CAAGCCCGAG CTAAACTAGA GGCAGAAGGG 
AAAATTCCAA AGGAGAGAAG GAAATACCTG CATGAGTCTC GGCACCGTCA TGCCATGGCA 
CGGAAGCGTG GTGAAGGTGG ACGATTTTTC TCTCCAAAGG AAAAGGATAG TCCCCATATG 
CAGGATCCAA ACCAAGCCGA TGAAGAAGCA ATGACACAGA TCATCCGAGT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068351.1
CDS	179..1135
Translation	MEQYTANSNSSTEQIVVQAGQIQQQVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Target ORF information:

RefSeq Version	NM_021705.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021705.3

ORF Insert Sequence:

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGGTCCA AGGGCAGCCA TTAATGGTGC AGGTCAGTGG AGGCCAGCTA 
ATCACATCAA CTGGCCAACC CATCATGGTC CAGGCTGTCC CTGGTGGACA AGGTCAAACC 
ATCATGCAAG TACCTGTTTC TGGAACACAG GGTTTGCAGC AAATACAGTT GGTCCCACCT 
GGACAGATCC AGATCCAGGG TGGACAGGCT GTGCAGGTGC AGGGCCAGCA GGGCCAGACC 
CAGCAGATCA TCATCCAGCA GCCCCAGACG GCTGTCACTG CTGGCCAGAC TCAGACACAG 
CAGCAGATTG CTGTCCAGGG ACAGCAAGTG GCACAGACTG CTGAAGGGCA GACCATCGTC 
TATCAACCAG TTAATGCAGA TGGCACCATT CTCCAGCAAG TTACAGTCCC TGTTTCAGGC 
ATGATCACTA TCCCAGCAGC CAGTTTGGCA GGAGCACAGA TTGTTCAAAC AGGAGCCAAT 
ACCAACACAA CCAGCAGTGG GCAAGGGACT GTCACTGTGA CACTACCAGT GGCAGGCAAT 
GTGGTCAATT CAGGAGGGAT GGTCATGATG GTTCCTGGGG CTGGCTCTGT GCCTGCTATC 
CAAAGAATCC CTCTACCTGG AGCAGAGATG CTTGAAGAAG AGCCTCTCTA CGTGAATGCC 
AAACAATACC ACCGTATTCT TAAGAGGAGG CAAGCCCGAG CTAAACTAGA GGCAGAAGGG 
AAAATTCCAA AGGAGAGAAG GAAATACCTG CATGAGTCTC GGCACCGTCA TGCCATGGCA 
CGGAAGCGTG GTGAAGGTGG ACGATTTTTC TCTCCAAAGG AAAAGGATAG TCCCCATATG 
CAGGATCCAA ACCAAGCCGA TGAAGAAGCA ATGACACAGA TCATCCGAGT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFYA ( NM_021705.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_068351.1 Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09167
Clone ID Related Accession (Same CDS sequence)	NM_021705.3 , NM_021705.4
Accession Version	NM_021705.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-15
Organism	Homo sapiens(human)
Product	nuclear transcription factor Y subunit alpha isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM561405.1, BC039244.1, AL031778.1 and BQ184804.1. On Jun 2, 2019 this sequence version replaced NM_021705.3. Transcript Variant: This variant (2) is missing alternate exon B, resulting in the short isoform, isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.276525.1, SRR1803615.64636.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGGTCCA AGGGCAGCCA TTAATGGTGC AGGTCAGTGG AGGCCAGCTA 
ATCACATCAA CTGGCCAACC CATCATGGTC CAGGCTGTCC CTGGTGGACA AGGTCAAACC 
ATCATGCAAG TACCTGTTTC TGGAACACAG GGTTTGCAGC AAATACAGTT GGTCCCACCT 
GGACAGATCC AGATCCAGGG TGGACAGGCT GTGCAGGTGC AGGGCCAGCA GGGCCAGACC 
CAGCAGATCA TCATCCAGCA GCCCCAGACG GCTGTCACTG CTGGCCAGAC TCAGACACAG 
CAGCAGATTG CTGTCCAGGG ACAGCAAGTG GCACAGACTG CTGAAGGGCA GACCATCGTC 
TATCAACCAG TTAATGCAGA TGGCACCATT CTCCAGCAAG TTACAGTCCC TGTTTCAGGC 
ATGATCACTA TCCCAGCAGC CAGTTTGGCA GGAGCACAGA TTGTTCAAAC AGGAGCCAAT 
ACCAACACAA CCAGCAGTGG GCAAGGGACT GTCACTGTGA CACTACCAGT GGCAGGCAAT 
GTGGTCAATT CAGGAGGGAT GGTCATGATG GTTCCTGGGG CTGGCTCTGT GCCTGCTATC 
CAAAGAATCC CTCTACCTGG AGCAGAGATG CTTGAAGAAG AGCCTCTCTA CGTGAATGCC 
AAACAATACC ACCGTATTCT TAAGAGGAGG CAAGCCCGAG CTAAACTAGA GGCAGAAGGG 
AAAATTCCAA AGGAGAGAAG GAAATACCTG CATGAGTCTC GGCACCGTCA TGCCATGGCA 
CGGAAGCGTG GTGAAGGTGG ACGATTTTTC TCTCCAAAGG AAAAGGATAG TCCCCATATG 
CAGGATCCAA ACCAAGCCGA TGAAGAAGCA ATGACACAGA TCATCCGAGT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068351.1
CDS	173..1129
Translation	MEQYTANSNSSTEQIVVQAGQIQQQVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDSPHMQDPNQADEEAMTQIIRVS

Target ORF information:

RefSeq Version	NM_021705.4
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear transcription factor Y subunit alpha (NFYA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021705.4

ORF Insert Sequence:

ATGGAGCAGT ATACAGCAAA CAGCAATAGT TCGACAGAGC AGATTGTTGT CCAGGCAGGA 
CAGATTCAGC AGCAGGTCCA AGGGCAGCCA TTAATGGTGC AGGTCAGTGG AGGCCAGCTA 
ATCACATCAA CTGGCCAACC CATCATGGTC CAGGCTGTCC CTGGTGGACA AGGTCAAACC 
ATCATGCAAG TACCTGTTTC TGGAACACAG GGTTTGCAGC AAATACAGTT GGTCCCACCT 
GGACAGATCC AGATCCAGGG TGGACAGGCT GTGCAGGTGC AGGGCCAGCA GGGCCAGACC 
CAGCAGATCA TCATCCAGCA GCCCCAGACG GCTGTCACTG CTGGCCAGAC TCAGACACAG 
CAGCAGATTG CTGTCCAGGG ACAGCAAGTG GCACAGACTG CTGAAGGGCA GACCATCGTC 
TATCAACCAG TTAATGCAGA TGGCACCATT CTCCAGCAAG TTACAGTCCC TGTTTCAGGC 
ATGATCACTA TCCCAGCAGC CAGTTTGGCA GGAGCACAGA TTGTTCAAAC AGGAGCCAAT 
ACCAACACAA CCAGCAGTGG GCAAGGGACT GTCACTGTGA CACTACCAGT GGCAGGCAAT 
GTGGTCAATT CAGGAGGGAT GGTCATGATG GTTCCTGGGG CTGGCTCTGT GCCTGCTATC 
CAAAGAATCC CTCTACCTGG AGCAGAGATG CTTGAAGAAG AGCCTCTCTA CGTGAATGCC 
AAACAATACC ACCGTATTCT TAAGAGGAGG CAAGCCCGAG CTAAACTAGA GGCAGAAGGG 
AAAATTCCAA AGGAGAGAAG GAAATACCTG CATGAGTCTC GGCACCGTCA TGCCATGGCA 
CGGAAGCGTG GTGAAGGTGG ACGATTTTTC TCTCCAAAGG AAAAGGATAG TCCCCATATG 
CAGGATCCAA ACCAAGCCGA TGAAGAAGCA ATGACACAGA TCATCCGAGT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Prognostic role of NF-YA splicing isoforms and Lamin A status in low grade endometrial cancer.
Oncotarget8(5)7935-7945(2017 Jan)
Cicchillitti L,Corrado G,Carosi M,Dabrowska ME,Loria R,Falcioni R,Cutillo G,Piaggio G,Vizza E

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NFYA cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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