NFKBIA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NFKBIA
Entrez Gene ID	4792
Full Name	NFKB inhibitor alpha
Synonyms	IKBA,MAD-3,NFKBI
General protein information	Preferred Names NFKB inhibitor alpha Names NF-kappa-B inhibitor alpha I-kappa-B-alpha IkappaBalpha ikB-alpha major histocompatibility complex enhancer-binding protein MAD3 nuclear factor of kappa light chain gene enhancer in B-cells nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q13.2
Summary	This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].
Disorder MIM:	164008
Disorder Html:	Ectodermal dysplasia, anhidrotic, with T-cell immunodeficiency, 612132 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_020529.2	NP_065390.1	NF-kappa-B inhibitor alpha
NM_020529.3	NP_065390.1	NF-kappa-B inhibitor alpha

Pathways from BioSystems

Homologies

	NFKBIA	XP_001087842.1
Canis lupus familiaris (dog)	NFKBIA	XP_537413.3
Bos taurus (cattle)	NFKBIA	NP_001039333.1
Danio rerio (zebrafish)	nfkbiaa	NP_998349.1
Pan troglodytes (chimpanzee)	NFKBIA	XP_522823.2
Rattus norvegicus (Norway rat)	Nfkbia	NP_001099190.2
Gallus gallus (chicken)	NFKBIA	NP_001001472.2
Danio rerio (zebrafish)	nfkbiab	NP_955923.1
Anopheles gambiae (African malaria mosquito)	CACT	XP_317542.4
Homo sapiens (human)	NFKBIA	NP_065390.1
Mus musculus (house mouse)	Nfkbia	NP_035037.2
Xenopus tropicalis (tropical clawed frog)	nfkbia	NP_001004851.1
Drosophila melanogaster (fruit fly)	cact	NP_001260496.1

Gene Ontology

The following NFKBIA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFKBIA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19341	NM_020529.3 Latest version!	Homo sapiens NFKB inhibitor alpha (NFKBIA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu19341	NM_020529.2	Homo sapiens NFKB inhibitor alpha (NFKBIA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NFKBIA ( NM_020529.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_065390.1 Homo sapiens NFKB inhibitor alpha (NFKBIA), mRNA.

Price & Availability↑

CloneID	OHu19341
Clone ID Related Accession (Same CDS sequence)	NM_020529.2 , NM_020529.3
Accession Version	NM_020529.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL133163.3, BC004983.1 and BU737609.1. This sequence is a reference standard in the RefSeqGene project. On Feb 23, 2008 this sequence version replaced NM_020529.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.134380.1, BC002601.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTTCCAGG CGGCCGAGCG CCCCCAGGAG TGGGCCATGG AGGGCCCCCG CGACGGGCTG 
AAGAAGGAGC GGCTACTGGA CGACCGCCAC GACAGCGGCC TGGACTCCAT GAAAGACGAG 
GAGTACGAGC AGATGGTCAA GGAGCTGCAG GAGATCCGCC TCGAGCCGCA GGAGGTGCCG 
CGCGGCTCGG AGCCCTGGAA GCAGCAGCTC ACCGAGGACG GGGACTCGTT CCTGCACTTG 
GCCATCATCC ATGAAGAAAA GGCACTGACC ATGGAAGTGA TCCGCCAGGT GAAGGGAGAC 
CTGGCCTTCC TCAACTTCCA GAACAACCTG CAGCAGACTC CACTCCACTT GGCTGTGATC 
ACCAACCAGC CAGAAATTGC TGAGGCACTT CTGGGAGCTG GCTGTGATCC TGAGCTCCGA 
GACTTTCGAG GAAATACCCC CCTACACCTT GCCTGTGAGC AGGGCTGCCT GGCCAGCGTG 
GGAGTCCTGA CTCAGTCCTG CACCACCCCG CACCTCCACT CCATCCTGAA GGCTACCAAC 
TACAATGGCC ACACGTGTCT ACACTTAGCC TCTATCCATG GCTACCTGGG CATCGTGGAG 
CTTTTGGTGT CCTTGGGTGC TGATGTCAAT GCTCAGGAGC CCTGTAATGG CCGGACTGCC 
CTTCACCTCG CAGTGGACCT GCAAAATCCT GACCTGGTGT CACTCCTGTT GAAGTGTGGG 
GCTGATGTCA ACAGAGTTAC CTACCAGGGC TATTCTCCCT ACCAGCTCAC CTGGGGCCGC 
CCAAGCACCC GGATACAGCA GCAGCTGGGC CAGCTGACAC TAGAAAACCT TCAGATGCTG 
CCAGAGAGTG AGGATGAGGA GAGCTATGAC ACAGAGTCAG AGTTCACGGA GTTCACAGAG 
GACGAGCTGC CCTATGATGA CTGTGTGTTT GGAGGCCAGC GTCTGACGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065390.1
CDS	111..1064
Translation	MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL

Target ORF information:

RefSeq Version	NM_020529.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor alpha (NFKBIA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020529.2

ORF Insert Sequence:

ATGTTCCAGG CGGCCGAGCG CCCCCAGGAG TGGGCCATGG AGGGCCCCCG CGACGGGCTG 
AAGAAGGAGC GGCTACTGGA CGACCGCCAC GACAGCGGCC TGGACTCCAT GAAAGACGAG 
GAGTACGAGC AGATGGTCAA GGAGCTGCAG GAGATCCGCC TCGAGCCGCA GGAGGTGCCG 
CGCGGCTCGG AGCCCTGGAA GCAGCAGCTC ACCGAGGACG GGGACTCGTT CCTGCACTTG 
GCCATCATCC ATGAAGAAAA GGCACTGACC ATGGAAGTGA TCCGCCAGGT GAAGGGAGAC 
CTGGCCTTCC TCAACTTCCA GAACAACCTG CAGCAGACTC CACTCCACTT GGCTGTGATC 
ACCAACCAGC CAGAAATTGC TGAGGCACTT CTGGGAGCTG GCTGTGATCC TGAGCTCCGA 
GACTTTCGAG GAAATACCCC CCTACACCTT GCCTGTGAGC AGGGCTGCCT GGCCAGCGTG 
GGAGTCCTGA CTCAGTCCTG CACCACCCCG CACCTCCACT CCATCCTGAA GGCTACCAAC 
TACAATGGCC ACACGTGTCT ACACTTAGCC TCTATCCATG GCTACCTGGG CATCGTGGAG 
CTTTTGGTGT CCTTGGGTGC TGATGTCAAT GCTCAGGAGC CCTGTAATGG CCGGACTGCC 
CTTCACCTCG CAGTGGACCT GCAAAATCCT GACCTGGTGT CACTCCTGTT GAAGTGTGGG 
GCTGATGTCA ACAGAGTTAC CTACCAGGGC TATTCTCCCT ACCAGCTCAC CTGGGGCCGC 
CCAAGCACCC GGATACAGCA GCAGCTGGGC CAGCTGACAC TAGAAAACCT TCAGATGCTG 
CCAGAGAGTG AGGATGAGGA GAGCTATGAC ACAGAGTCAG AGTTCACGGA GTTCACAGAG 
GACGAGCTGC CCTATGATGA CTGTGTGTTT GGAGGCCAGC GTCTGACGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFKBIA ( NM_020529.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065390.1 Homo sapiens NFKB inhibitor alpha (NFKBIA), mRNA.

Price & Availability↑

CloneID	OHu19341
Clone ID Related Accession (Same CDS sequence)	NM_020529.2 , NM_020529.3
Accession Version	NM_020529.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 954bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	NF-kappa-B inhibitor alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL133163.3 and BC004983.1. On Dec 4, 2019 this sequence version replaced NM_020529.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004983.1, M69043.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTTCCAGG CGGCCGAGCG CCCCCAGGAG TGGGCCATGG AGGGCCCCCG CGACGGGCTG 
AAGAAGGAGC GGCTACTGGA CGACCGCCAC GACAGCGGCC TGGACTCCAT GAAAGACGAG 
GAGTACGAGC AGATGGTCAA GGAGCTGCAG GAGATCCGCC TCGAGCCGCA GGAGGTGCCG 
CGCGGCTCGG AGCCCTGGAA GCAGCAGCTC ACCGAGGACG GGGACTCGTT CCTGCACTTG 
GCCATCATCC ATGAAGAAAA GGCACTGACC ATGGAAGTGA TCCGCCAGGT GAAGGGAGAC 
CTGGCCTTCC TCAACTTCCA GAACAACCTG CAGCAGACTC CACTCCACTT GGCTGTGATC 
ACCAACCAGC CAGAAATTGC TGAGGCACTT CTGGGAGCTG GCTGTGATCC TGAGCTCCGA 
GACTTTCGAG GAAATACCCC CCTACACCTT GCCTGTGAGC AGGGCTGCCT GGCCAGCGTG 
GGAGTCCTGA CTCAGTCCTG CACCACCCCG CACCTCCACT CCATCCTGAA GGCTACCAAC 
TACAATGGCC ACACGTGTCT ACACTTAGCC TCTATCCATG GCTACCTGGG CATCGTGGAG 
CTTTTGGTGT CCTTGGGTGC TGATGTCAAT GCTCAGGAGC CCTGTAATGG CCGGACTGCC 
CTTCACCTCG CAGTGGACCT GCAAAATCCT GACCTGGTGT CACTCCTGTT GAAGTGTGGG 
GCTGATGTCA ACAGAGTTAC CTACCAGGGC TATTCTCCCT ACCAGCTCAC CTGGGGCCGC 
CCAAGCACCC GGATACAGCA GCAGCTGGGC CAGCTGACAC TAGAAAACCT TCAGATGCTG 
CCAGAGAGTG AGGATGAGGA GAGCTATGAC ACAGAGTCAG AGTTCACGGA GTTCACAGAG 
GACGAGCTGC CCTATGATGA CTGTGTGTTT GGAGGCCAGC GTCTGACGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065390.1
CDS	106..1059
Translation	MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL

Target ORF information:

RefSeq Version	NM_020529.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NFKB inhibitor alpha (NFKBIA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020529.3

ORF Insert Sequence:

ATGTTCCAGG CGGCCGAGCG CCCCCAGGAG TGGGCCATGG AGGGCCCCCG CGACGGGCTG 
AAGAAGGAGC GGCTACTGGA CGACCGCCAC GACAGCGGCC TGGACTCCAT GAAAGACGAG 
GAGTACGAGC AGATGGTCAA GGAGCTGCAG GAGATCCGCC TCGAGCCGCA GGAGGTGCCG 
CGCGGCTCGG AGCCCTGGAA GCAGCAGCTC ACCGAGGACG GGGACTCGTT CCTGCACTTG 
GCCATCATCC ATGAAGAAAA GGCACTGACC ATGGAAGTGA TCCGCCAGGT GAAGGGAGAC 
CTGGCCTTCC TCAACTTCCA GAACAACCTG CAGCAGACTC CACTCCACTT GGCTGTGATC 
ACCAACCAGC CAGAAATTGC TGAGGCACTT CTGGGAGCTG GCTGTGATCC TGAGCTCCGA 
GACTTTCGAG GAAATACCCC CCTACACCTT GCCTGTGAGC AGGGCTGCCT GGCCAGCGTG 
GGAGTCCTGA CTCAGTCCTG CACCACCCCG CACCTCCACT CCATCCTGAA GGCTACCAAC 
TACAATGGCC ACACGTGTCT ACACTTAGCC TCTATCCATG GCTACCTGGG CATCGTGGAG 
CTTTTGGTGT CCTTGGGTGC TGATGTCAAT GCTCAGGAGC CCTGTAATGG CCGGACTGCC 
CTTCACCTCG CAGTGGACCT GCAAAATCCT GACCTGGTGT CACTCCTGTT GAAGTGTGGG 
GCTGATGTCA ACAGAGTTAC CTACCAGGGC TATTCTCCCT ACCAGCTCAC CTGGGGCCGC 
CCAAGCACCC GGATACAGCA GCAGCTGGGC CAGCTGACAC TAGAAAACCT TCAGATGCTG 
CCAGAGAGTG AGGATGAGGA GAGCTATGAC ACAGAGTCAG AGTTCACGGA GTTCACAGAG 
GACGAGCTGC CCTATGATGA CTGTGTGTTT GGAGGCCAGC GTCTGACGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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NFKBIA cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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