Gene Symbol | NFE2L2 |
Entrez Gene ID | 4780 |
Full Name | nuclear factor, erythroid 2 like 2 |
Synonyms | HEBP1,IMDDHH,NRF2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]. |
Disorder MIM: | |
Disorder Html: | Immunodeficiency, developmental delay, and hypohomocysteinemia, 617744 (3) |