F8A3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	F8A3
Entrez Gene ID	474384
Full Name	coagulation factor VIII associated 3
General protein information	Preferred Names coagulation factor VIII associated 3 Names factor VIII intron 22 protein coagulation factor VIII-associated (intronic transcript) 3 cpG island protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq28
Summary	This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most telomeric copy. Although its function is unknown, the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII, this gene is transcribed abundantly in a wide variety of cell types. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007524.2	NP_001007525.1	40-kDa huntingtin-associated protein
NM_001007524.1	NP_001007525.1	factor VIII intron 22 protein

Pathways from BioSystems

Homologies

	F8A1	XP_001091814.1
Bos taurus (cattle)	LOC617475	XP_002699745.1
Rattus norvegicus (Norway rat)	F8a1	NP_001102793.1
Homo sapiens (human)	F8A2	NP_001007524.1
Homo sapiens (human)	F8A1	NP_036283.2
Mus musculus (house mouse)	F8a	NP_032004.2
Danio rerio (zebrafish)	zgc:101679	NP_001006078.1
Homo sapiens (human)	F8A3	NP_001007525.1
Xenopus tropicalis (tropical clawed frog)	f8a1	NP_001072171.1

Gene Ontology
Bibliography

Related articles in PubMed

The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity.
Huang ZN, Her LS
Molecular neurobiology(2016 Nov)

Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.
Pal A, Severin F, Lommer B, Shevchenko A, Zerial M
The Journal of cell biology172(4)605-18(2006 Feb)

Gene conversion and evolution of Xq28 duplicons involved in recurring inversions causing severe hemophilia A.
Bagnall RD, Ayres KL, Green PM, Giannelli F
Genome research15(2)214-23(2005 Feb)

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S
EMBO reports1(3)287-92(2000 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following F8A3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F8A3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29434	NM_001007524.2 Latest version!	Homo sapiens coagulation factor VIII associated 3 (F8A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29434	NM_001007524.1	Homo sapiens coagulation factor VIII associated 3 (F8A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

F8A3 ( NM_001007524.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001007525.1 Homo sapiens coagulation factor VIII associated 3 (F8A3), mRNA.

Price & Availability↑

CloneID	OHu29434
Clone ID Related Accession (Same CDS sequence)	NM_001007524.2 , NM_001007524.1
Accession Version	NM_001007524.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	40-kDa huntingtin-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX571846.3. On Dec 4, 2019 this sequence version replaced NM_001007524.1. ##Evidence-Data-START## Transcript is intronless :: AL554983.3, AL582641.3 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCAG CGGCTGCAGG CCTGGGCGGC GGCGGCGCCG GCCCGGGACC CGAGGCCGGG 
GACTTCCTGG CCCGCTACCG GCTGGTATCG AACAAGCTGA AGAAGCGGTT CCTGCGGAAG 
CCGAACGTGG CGGAGGCCGG CGAGCAGTTC GGACAGCTGG GCCGGGAGCT GCGCGCCCAG 
GAGTGTCTGC CCTACGCGGC CTGGTGCCAG CTGGCGGTGG CGCGCTGCCA GCAGGCGCTC 
TTCCACGGGC CCGGGGAGGC GCTGGCCCTC ACCGAGGCCG CCCGCCTCTT CCTGCGGCAG 
GAGCGCGACG CGCGCCAGCG CCTGGTCTGC CCCGCCGCCT ACGGGGAGCC GCTGCAGGCC 
GCCGCCAGCG CCCTGGGCGC CGCGGTGCGT CTGCACCTCG AGCTGGGCCA GCCGGCCGCC 
GCCGCCGCCC TCTGCCTCGA GCTGGCCGCC GCCCTGCGCG ACCTGGGCCA GCCGGCCGCC 
GCCGCCGGTC ACTTCCAGCG CGCCGCCCAG CTCCAGCTGC CCCAGCTGCC CCTGGCCGCG 
CTGCAGGCGC TTGGCGAGGC CGCCTCCTGC CAGCTGCTGG CGCGCGACTA CACCGGCGCC 
CTGGCGGTCT TCACGCGCAT GCAGCGCCTG GCGCGGGAGC ACGGCAGCCA CCCGGTGCAG 
TCACTGCCGC CGCCCCCGCC GCCGGCACCC CAGCCCGGGC CCGGGGCGAC GCCCGCCCTA 
CCGGCCGCGC TGCTTCCTCC GAACTCCGGC TCGGCGGCGC CCTCTCCCGC CGCCCTGGGC 
GCCTTCTCGG ACGTGCTGGT CCGCTGCGAG GTGTCCCGCG TGCTGCTGCT GCTCCTCCTG 
CAACCACCGC CCGCCAAGCT GCTGCCGGAG CACGCCCAGA CCCTGGAGAA GTACTCCTGG 
GAGGCTTTTG ACAGCCACGG GCAGGAGAGC AGCGGCCAGC TTCCCGAGGA GCTCTTTCTG 
CTGCTCCAGT CTTTGGTCAT GGCTACCCAC GAAAAGGACA CGGAAGCCAT CAAGTCGCTG 
CAGGTGGAGA TGTGGCCACT GTTGACTGCT GAGCAGAACC ACCTCCTTCA CCTCGTTCTG 
CAAGAAACCA TCTCCCCCTC AGGACAGGGA GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007525.1
CDS	21..1136
Translation	MAAAAAGLGGGGAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGEAASCQLLARDYTGALAVFTRMQRLAREHGSHPVQSLPPPPPPAPQPGPGATPALPAALLPPNSGSAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDSHGQESSGQLPEELFLLLQSLVMATHEKDTEAIKSLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV

Target ORF information:

RefSeq Version	NM_001007524.2
Organism	Homo sapiens(human)
Definition	Homo sapiens coagulation factor VIII associated 3 (F8A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007524.2

ORF Insert Sequence:

ATGGCGGCAG CGGCTGCAGG CCTGGGCGGC GGCGGCGCCG GCCCGGGACC CGAGGCCGGG 
GACTTCCTGG CCCGCTACCG GCTGGTATCG AACAAGCTGA AGAAGCGGTT CCTGCGGAAG 
CCGAACGTGG CGGAGGCCGG CGAGCAGTTC GGACAGCTGG GCCGGGAGCT GCGCGCCCAG 
GAGTGTCTGC CCTACGCGGC CTGGTGCCAG CTGGCGGTGG CGCGCTGCCA GCAGGCGCTC 
TTCCACGGGC CCGGGGAGGC GCTGGCCCTC ACCGAGGCCG CCCGCCTCTT CCTGCGGCAG 
GAGCGCGACG CGCGCCAGCG CCTGGTCTGC CCCGCCGCCT ACGGGGAGCC GCTGCAGGCC 
GCCGCCAGCG CCCTGGGCGC CGCGGTGCGT CTGCACCTCG AGCTGGGCCA GCCGGCCGCC 
GCCGCCGCCC TCTGCCTCGA GCTGGCCGCC GCCCTGCGCG ACCTGGGCCA GCCGGCCGCC 
GCCGCCGGTC ACTTCCAGCG CGCCGCCCAG CTCCAGCTGC CCCAGCTGCC CCTGGCCGCG 
CTGCAGGCGC TTGGCGAGGC CGCCTCCTGC CAGCTGCTGG CGCGCGACTA CACCGGCGCC 
CTGGCGGTCT TCACGCGCAT GCAGCGCCTG GCGCGGGAGC ACGGCAGCCA CCCGGTGCAG 
TCACTGCCGC CGCCCCCGCC GCCGGCACCC CAGCCCGGGC CCGGGGCGAC GCCCGCCCTA 
CCGGCCGCGC TGCTTCCTCC GAACTCCGGC TCGGCGGCGC CCTCTCCCGC CGCCCTGGGC 
GCCTTCTCGG ACGTGCTGGT CCGCTGCGAG GTGTCCCGCG TGCTGCTGCT GCTCCTCCTG 
CAACCACCGC CCGCCAAGCT GCTGCCGGAG CACGCCCAGA CCCTGGAGAA GTACTCCTGG 
GAGGCTTTTG ACAGCCACGG GCAGGAGAGC AGCGGCCAGC TTCCCGAGGA GCTCTTTCTG 
CTGCTCCAGT CTTTGGTCAT GGCTACCCAC GAAAAGGACA CGGAAGCCAT CAAGTCGCTG 
CAGGTGGAGA TGTGGCCACT GTTGACTGCT GAGCAGAACC ACCTCCTTCA CCTCGTTCTG 
CAAGAAACCA TCTCCCCCTC AGGACAGGGA GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F8A3 ( NM_001007524.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001007525.1 Homo sapiens coagulation factor VIII associated 3 (F8A3), mRNA.

Price & Availability↑

CloneID	OHu29434
Clone ID Related Accession (Same CDS sequence)	NM_001007524.2 , NM_001007524.1
Accession Version	NM_001007524.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	factor VIII intron 22 protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY620001.1. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCGGCAG CGGCTGCAGG CCTGGGCGGC GGCGGCGCCG GCCCGGGACC CGAGGCCGGG 
GACTTCCTGG CCCGCTACCG GCTGGTATCG AACAAGCTGA AGAAGCGGTT CCTGCGGAAG 
CCGAACGTGG CGGAGGCCGG CGAGCAGTTC GGACAGCTGG GCCGGGAGCT GCGCGCCCAG 
GAGTGTCTGC CCTACGCGGC CTGGTGCCAG CTGGCGGTGG CGCGCTGCCA GCAGGCGCTC 
TTCCACGGGC CCGGGGAGGC GCTGGCCCTC ACCGAGGCCG CCCGCCTCTT CCTGCGGCAG 
GAGCGCGACG CGCGCCAGCG CCTGGTCTGC CCCGCCGCCT ACGGGGAGCC GCTGCAGGCC 
GCCGCCAGCG CCCTGGGCGC CGCGGTGCGT CTGCACCTCG AGCTGGGCCA GCCGGCCGCC 
GCCGCCGCCC TCTGCCTCGA GCTGGCCGCC GCCCTGCGCG ACCTGGGCCA GCCGGCCGCC 
GCCGCCGGTC ACTTCCAGCG CGCCGCCCAG CTCCAGCTGC CCCAGCTGCC CCTGGCCGCG 
CTGCAGGCGC TTGGCGAGGC CGCCTCCTGC CAGCTGCTGG CGCGCGACTA CACCGGCGCC 
CTGGCGGTCT TCACGCGCAT GCAGCGCCTG GCGCGGGAGC ACGGCAGCCA CCCGGTGCAG 
TCACTGCCGC CGCCCCCGCC GCCGGCACCC CAGCCCGGGC CCGGGGCGAC GCCCGCCCTA 
CCGGCCGCGC TGCTTCCTCC GAACTCCGGC TCGGCGGCGC CCTCTCCCGC CGCCCTGGGC 
GCCTTCTCGG ACGTGCTGGT CCGCTGCGAG GTGTCCCGCG TGCTGCTGCT GCTCCTCCTG 
CAACCACCGC CCGCCAAGCT GCTGCCGGAG CACGCCCAGA CCCTGGAGAA GTACTCCTGG 
GAGGCTTTTG ACAGCCACGG GCAGGAGAGC AGCGGCCAGC TTCCCGAGGA GCTCTTTCTG 
CTGCTCCAGT CTTTGGTCAT GGCTACCCAC GAAAAGGACA CGGAAGCCAT CAAGTCGCTG 
CAGGTGGAGA TGTGGCCACT GTTGACTGCT GAGCAGAACC ACCTCCTTCA CCTCGTTCTG 
CAAGAAACCA TCTCCCCCTC AGGACAGGGA GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007525.1
CDS	1..1116
Translation	MAAAAAGLGGGGAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGEAASCQLLARDYTGALAVFTRMQRLAREHGSHPVQSLPPPPPPAPQPGPGATPALPAALLPPNSGSAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDSHGQESSGQLPEELFLLLQSLVMATHEKDTEAIKSLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV

Target ORF information:

RefSeq Version	NM_001007524.1
Organism	Homo sapiens(human)
Definition	Homo sapiens coagulation factor VIII associated 3 (F8A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007524.1

ORF Insert Sequence:

ATGGCGGCAG CGGCTGCAGG CCTGGGCGGC GGCGGCGCCG GCCCGGGACC CGAGGCCGGG 
GACTTCCTGG CCCGCTACCG GCTGGTATCG AACAAGCTGA AGAAGCGGTT CCTGCGGAAG 
CCGAACGTGG CGGAGGCCGG CGAGCAGTTC GGACAGCTGG GCCGGGAGCT GCGCGCCCAG 
GAGTGTCTGC CCTACGCGGC CTGGTGCCAG CTGGCGGTGG CGCGCTGCCA GCAGGCGCTC 
TTCCACGGGC CCGGGGAGGC GCTGGCCCTC ACCGAGGCCG CCCGCCTCTT CCTGCGGCAG 
GAGCGCGACG CGCGCCAGCG CCTGGTCTGC CCCGCCGCCT ACGGGGAGCC GCTGCAGGCC 
GCCGCCAGCG CCCTGGGCGC CGCGGTGCGT CTGCACCTCG AGCTGGGCCA GCCGGCCGCC 
GCCGCCGCCC TCTGCCTCGA GCTGGCCGCC GCCCTGCGCG ACCTGGGCCA GCCGGCCGCC 
GCCGCCGGTC ACTTCCAGCG CGCCGCCCAG CTCCAGCTGC CCCAGCTGCC CCTGGCCGCG 
CTGCAGGCGC TTGGCGAGGC CGCCTCCTGC CAGCTGCTGG CGCGCGACTA CACCGGCGCC 
CTGGCGGTCT TCACGCGCAT GCAGCGCCTG GCGCGGGAGC ACGGCAGCCA CCCGGTGCAG 
TCACTGCCGC CGCCCCCGCC GCCGGCACCC CAGCCCGGGC CCGGGGCGAC GCCCGCCCTA 
CCGGCCGCGC TGCTTCCTCC GAACTCCGGC TCGGCGGCGC CCTCTCCCGC CGCCCTGGGC 
GCCTTCTCGG ACGTGCTGGT CCGCTGCGAG GTGTCCCGCG TGCTGCTGCT GCTCCTCCTG 
CAACCACCGC CCGCCAAGCT GCTGCCGGAG CACGCCCAGA CCCTGGAGAA GTACTCCTGG 
GAGGCTTTTG ACAGCCACGG GCAGGAGAGC AGCGGCCAGC TTCCCGAGGA GCTCTTTCTG 
CTGCTCCAGT CTTTGGTCAT GGCTACCCAC GAAAAGGACA CGGAAGCCAT CAAGTCGCTG 
CAGGTGGAGA TGTGGCCACT GTTGACTGCT GAGCAGAACC ACCTCCTTCA CCTCGTTCTG 
CAAGAAACCA TCTCCCCCTC AGGACAGGGA GTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity.
Molecular neurobiology(2016 Nov)
Huang ZN,Her LS

Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.
The Journal of cell biology172(4)605-18(2006 Feb)
Pal A,Severin F,Lommer B,Shevchenko A,Zerial M

Gene conversion and evolution of Xq28 duplicons involved in recurring inversions causing severe hemophilia A.
Genome research15(2)214-23(2005 Feb)
Bagnall RD,Ayres KL,Green PM,Giannelli F

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.
EMBO reports1(3)287-92(2000 Sep)
Simpson JC,Wellenreuther R,Poustka A,Pepperkok R,Wiemann S

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F8A3 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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