NDUFC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NDUFC1
Entrez Gene ID	4717
Full Name	NADH:ubiquinone oxidoreductase subunit C1
Synonyms	KFYI
General protein information	Preferred Names NADH:ubiquinone oxidoreductase subunit C1 Names NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial CI-KFYI NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa NADH-ubiquinone oxidoreductase KFYI subunit complex I KFYI subunit complex I-KFYI
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q31.1
Summary	The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
Disorder MIM:	603844

mRNA and Protein(s)

mRNA	Protein	Name
NM_001184989.1	NP_001171918.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
NM_001184989.2	NP_001171918.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
NM_001184986.1	NP_001171915.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
NM_001184991.1	NP_001171920.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
NM_001184987.1	NP_001171916.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
NM_002494.3	NP_002485.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
NM_001184990.1	NP_001171919.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
NM_001184988.1	NP_001171917.1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	NDUFC1	NP_776989.1
Homo sapiens (human)	NDUFC1	NP_002485.1
	NDUFC1	XP_001087956.2
Canis lupus familiaris (dog)	NDUFC1	XP_005631837.1
Mus musculus (house mouse)	Ndufc1	NP_079799.1
Rattus norvegicus (Norway rat)	Ndufc1	XP_003749323.2

Gene Ontology
Bibliography

Related articles in PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT
Nature538(7623)123-126(2016 Oct)

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
Wang AG, Yoon SY, Oh JH, Jeon YJ, Kim M, Kim JM, Byun SS, Yang JO, Kim JH, Kim DG, Yeom YI, Yoo HS, Kim YS, Kim NS
Biochemical and biophysical research communications345(3)1022-32(2006 Jul)

Transcriptome analysis of human gastric cancer.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.
Loeffen JL, Triepels RH, van den Heuvel LP, Schuelke M, Buskens CA, Smeets RJ, Trijbels JM, Smeitink JA
Biochemical and biophysical research communications253(2)415-22(1998 Dec)

Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain.
Emahazion T, Beskow A, Gyllensten U, Brookes AJ
Cytogenetics and cell genetics82(1-2)115-9(1998)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NDUFC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NDUFC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08503	NM_001184991.1 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08503	NM_001184989.2 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08503	NM_001184986.1 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08503	NM_001184987.1 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08503	NM_001184990.1 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08503	NM_002494.3 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08503	NM_001184988.1 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu08503	NM_001184989.1	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NDUFC1 ( NM_001184989.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171918.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_001184989.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM768825.1, CB160001.1 and W56292.1. Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.520470.1, SRR1163657.427013.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171918.1
CDS	358..588
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_001184989.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184989.1

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFC1 ( NM_001184989.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171918.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_001184989.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB160001.1 and W56292.1. On Nov 24, 2018 this sequence version replaced NM_001184989.1. Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.520470.1, SRR1163657.427013.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000394223.2/ ENSP00000377770.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171918.1
CDS	284..514
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_001184989.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184989.2

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFC1 ( NM_001184986.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171915.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_001184986.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CX163301.1, CA313899.1 and W56292.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: CA313899.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171915.1
CDS	831..1061
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_001184986.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184986.1

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFC1 ( NM_001184991.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171920.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_001184991.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CX163301.1, CB047240.1, AC097376.3 and W56292.1. Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.160601.1, SRR1163655.636974.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171920.1
CDS	772..1002
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_001184991.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184991.1

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFC1 ( NM_001184987.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171916.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_001184987.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM768825.1, BU677336.1 and W56292.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BU677336.1, SRR1163658.512964.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171916.1
CDS	299..529
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_001184987.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184987.1

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFC1 ( NM_002494.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002485.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_002494.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG701467.1, BC107682.1, AC097376.3 and W56292.1. On May 29, 2010 this sequence version replaced NM_002494.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC107682.1, BM310149.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002485.1
CDS	434..664
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_002494.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002494.3

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFC1 ( NM_001184990.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171919.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_001184990.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM768825.1, CN347371.1, AC097376.3 and W56292.1. Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.384223.1, CN347371.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171919.1
CDS	295..525
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_001184990.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184990.1

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFC1 ( NM_001184988.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171917.1 Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu08503
Clone ID Related Accession (Same CDS sequence)	NM_001184989.1 , NM_001184989.2 , NM_001184986.1 , NM_001184991.1 , NM_001184987.1 , NM_002494.3 , NM_001184990.1 , NM_001184988.1
Accession Version	NM_001184988.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM768825.1 and W56292.1. On Aug 31, 2013 this sequence version replaced XM_005263026.1. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BM768825.1, BM831140.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171917.1
CDS	335..565
Translation	MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIKQHNEDILEYKRRNGLE

Target ORF information:

RefSeq Version	NM_001184988.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit C1 (NDUFC1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184988.1

ORF Insert Sequence:

ATGGCGCCGT CCGCCTTGCT GCGTCCCCTT TCCCGGCTGC TGGCCCCCGC CAGGCTCCCG 
AGCGGCCCTT CAGTGCGATC AAAGTTCTAC GTGCGAGAGC CGCCGAATGC CAAACCTGAC 
TGGCTGAAAG TTGGGTTCAC CTTGGGCACC ACTGTCTTCT TGTGGATCTA TCTCATCAAA 
CAACACAATG AAGATATTTT AGAGTACAAA AGAAGAAATG GGCTGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Nature538(7623)123-126(2016 Oct)
Stroud DA,Surgenor EE,Formosa LE,Reljic B,Frazier AE,Dibley MG,Osellame LD,Stait T,Beilharz TH,Thorburn DR,Salim A,Ryan MT

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
Biochemical and biophysical research communications345(3)1022-32(2006 Jul)
Wang AG,Yoon SY,Oh JH,Jeon YJ,Kim M,Kim JM,Byun SS,Yang JO,Kim JH,Kim DG,Yeom YI,Yoo HS,Kim YS,Kim NS

Transcriptome analysis of human gastric cancer.
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)
Oh JH,Yang JO,Hahn Y,Kim MR,Byun SS,Jeon YJ,Kim JM,Song KS,Noh SM,Kim S,Yoo HS,Kim YS,Kim NS

cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.
Biochemical and biophysical research communications253(2)415-22(1998 Dec)
Loeffen JL,Triepels RH,van den Heuvel LP,Schuelke M,Buskens CA,Smeets RJ,Trijbels JM,Smeitink JA

Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain.
Cytogenetics and cell genetics82(1-2)115-9(1998)
Emahazion T,Beskow A,Gyllensten U,Brookes AJ

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NDUFC1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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ORF Insert Sequence:

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ORF Insert Sequence:

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