Gene Symbol | MYOC |
Entrez Gene ID | 4653 |
Full Name | myocilin |
Synonyms | GLC1A,GPOA,JOAG,JOAG1,TIGR |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Glaucoma 1A, primary open angle, 137750 (3) |