Gene Symbol | MYCN |
Entrez Gene ID | 4613 |
Full Name | MYCN proto-oncogene, bHLH transcription factor |
Synonyms | MODED,N-myc,NMYC,ODED,bHLHe37 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]. |
Disorder MIM: | |
Disorder Html: | Feingold syndrome 1, 164280 (3) |