MSX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MSX1
Entrez Gene ID	4487
Full Name	msh homeobox 1
Synonyms	ECTD3,HOX7,HYD1,STHAG1
General protein information	Preferred Names msh homeobox 1 Names homeobox protein MSX-1 homeobox 7 homeobox protein Hox-7 msh homeo box 1 msh homeobox 1-like protein msh homeobox homolog 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p16.2
Summary	This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008].
Disorder MIM:	142983
Disorder Html:	Tooth agenesis, selective, 1, with or without orofacial cleft, 106600 (3); Orofacial cleft 5, 608874 (3); Ectodermal dysplasia 3, Witkop type, 189500 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002448.3	NP_002439.2	homeobox protein MSX-1

Pathways from BioSystems

Homologies

Homo sapiens (human)	MSX1	NP_002439.2
Mus musculus (house mouse)	Msx1	NP_034965.2
Rattus norvegicus (Norway rat)	Msx1	NP_112321.1
	MSX1	XP_001118871.2
Xenopus tropicalis (tropical clawed frog)	msx1	NP_001032329.1
Canis lupus familiaris (dog)	MSX1	XP_545946.2
Gallus gallus (chicken)	MSX1	NP_990819.1
Danio rerio (zebrafish)	msxe	NP_571348.1
Bos taurus (cattle)	MSX1	NP_777223.1
Pan troglodytes (chimpanzee)	MSX1	NP_001182191.1

Gene Ontology

The following MSX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MSX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu18516	NM_002448.3 Latest version!	Homo sapiens msh homeobox 1 (MSX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MSX1 ( NM_002448.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002439.2 Homo sapiens msh homeobox 1 (MSX1), mRNA.

Price & Availability↑

CloneID	OHu18516
Clone ID Related Accession (Same CDS sequence)	NM_002448.3
Accession Version	NM_002448.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	homeobox protein MSX-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU117561.1, BC067353.1 and AC092437.4. This sequence is a reference standard in the RefSeqGene project. On Dec 1, 2006 this sequence version replaced NM_002448.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M97676.1, BC021285.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000382723.5/ ENSP00000372170.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCCGG CTGCTGACAT GACTTCTTTG CCACTCGGTG TCAAAGTGGA GGACTCCGCC 
TTCGGCAAGC CGGCGGGGGG AGGCGCGGGC CAGGCCCCCA GCGCCGCCGC GGCCACGGCA 
GCCGCCATGG GCGCGGACGA GGAGGGGGCC AAGCCCAAAG TGTCCCCTTC GCTCCTGCCC 
TTCAGCGTGG AGGCGCTCAT GGCCGACCAC AGGAAGCCGG GGGCCAAGGA GAGCGCCCTG 
GCGCCCTCCG AGGGCGTGCA GGCGGCGGGT GGCTCGGCGC AGCCACTGGG CGTCCCGCCG 
GGGTCGCTGG GAGCCCCGGA CGCGCCCTCT TCGCCGCGGC CGCTCGGCCA TTTCTCGGTG 
GGGGGACTCC TCAAGCTGCC AGAAGATGCG CTCGTCAAAG CCGAGAGCCC CGAGAAGCCC 
GAGAGGACCC CGTGGATGCA GAGCCCCCGC TTCTCCCCGC CGCCGGCCAG GCGGCTGAGC 
CCCCCAGCCT GCACCCTCCG CAAACACAAG ACGAACCGTA AGCCGCGGAC GCCCTTCACC 
ACCGCGCAGC TGCTGGCGCT GGAGCGCAAG TTCCGCCAGA AGCAGTACCT GTCCATCGCC 
GAGCGCGCGG AGTTCTCCAG CTCGCTCAGC CTCACTGAGA CGCAGGTGAA GATATGGTTC 
CAGAACCGCC GCGCCAAGGC AAAGAGACTA CAAGAGGCAG AGCTGGAGAA GCTGAAGATG 
GCCGCCAAGC CCATGCTGCC ACCGGCTGCC TTCGGCCTCT CCTTCCCTCT CGGCGGCCCC 
GCAGCTGTAG CGGCCGCGGC GGGTGCCTCG CTCTACGGTG CCTCTGGCCC CTTCCAGCGC 
GCCGCGCTGC CTGTGGCGCC CGTGGGACTC TACACGGCCC ATGTGGGCTA CAGCATGTAC 
CACCTGACAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002439.2
CDS	236..1147
Translation	MAPAADMTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT

Target ORF information:

RefSeq Version	NM_002448.3
Organism	Homo sapiens(human)
Definition	Homo sapiens msh homeobox 1 (MSX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002448.3

ORF Insert Sequence:

ATGGCCCCGG CTGCTGACAT GACTTCTTTG CCACTCGGTG TCAAAGTGGA GGACTCCGCC 
TTCGGCAAGC CGGCGGGGGG AGGCGCGGGC CAGGCCCCCA GCGCCGCCGC GGCCACGGCA 
GCCGCCATGG GCGCGGACGA GGAGGGGGCC AAGCCCAAAG TGTCCCCTTC GCTCCTGCCC 
TTCAGCGTGG AGGCGCTCAT GGCCGACCAC AGGAAGCCGG GGGCCAAGGA GAGCGCCCTG 
GCGCCCTCCG AGGGCGTGCA GGCGGCGGGT GGCTCGGCGC AGCCACTGGG CGTCCCGCCG 
GGGTCGCTGG GAGCCCCGGA CGCGCCCTCT TCGCCGCGGC CGCTCGGCCA TTTCTCGGTG 
GGGGGACTCC TCAAGCTGCC AGAAGATGCG CTCGTCAAAG CCGAGAGCCC CGAGAAGCCC 
GAGAGGACCC CGTGGATGCA GAGCCCCCGC TTCTCCCCGC CGCCGGCCAG GCGGCTGAGC 
CCCCCAGCCT GCACCCTCCG CAAACACAAG ACGAACCGTA AGCCGCGGAC GCCCTTCACC 
ACCGCGCAGC TGCTGGCGCT GGAGCGCAAG TTCCGCCAGA AGCAGTACCT GTCCATCGCC 
GAGCGCGCGG AGTTCTCCAG CTCGCTCAGC CTCACTGAGA CGCAGGTGAA GATATGGTTC 
CAGAACCGCC GCGCCAAGGC AAAGAGACTA CAAGAGGCAG AGCTGGAGAA GCTGAAGATG 
GCCGCCAAGC CCATGCTGCC ACCGGCTGCC TTCGGCCTCT CCTTCCCTCT CGGCGGCCCC 
GCAGCTGTAG CGGCCGCGGC GGGTGCCTCG CTCTACGGTG CCTCTGGCCC CTTCCAGCGC 
GCCGCGCTGC CTGTGGCGCC CGTGGGACTC TACACGGCCC ATGTGGGCTA CAGCATGTAC 
CACCTGACAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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MSX1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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