MME gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_007289.2	NP_009220.2	neprilysin
XM_011512858.1	XP_011511160.1	neprilysin isoform X1
XM_011512855.1	XP_011511157.1	neprilysin isoform X1
NM_007288.3	NP_009219.2	neprilysin isoform a
NM_001354644.1	NP_001341573.1	neprilysin isoform b
NM_000902.3	NP_000893.2	neprilysin isoform a
XM_006713647.3	XP_006713710.1	neprilysin isoform X1
XM_006713646.2	XP_006713709.1	neprilysin isoform X1
XM_006713647.2	XP_006713710.1	neprilysin isoform X1
XM_011512855.2	XP_011511157.1	neprilysin isoform X1
NM_007289.4	NP_009220.2	neprilysin isoform a
XM_006713646.3	XP_006713709.1	neprilysin isoform X1
NM_007287.2	NP_009218.2	neprilysin isoform a
XM_011512856.2	XP_011511158.1	neprilysin isoform X1
XM_006713647.4	XP_006713710.1	neprilysin isoform X1
NM_000902.4	NP_000893.2	neprilysin isoform a
XM_011512857.1	XP_011511159.1	neprilysin isoform X1
XM_011512857.2	XP_011511159.1	neprilysin isoform X1
NM_001354643.1	NP_001341572.1	neprilysin isoform a
NM_007289.3	NP_009220.2	neprilysin isoform a
NM_007288.2	NP_009219.2	neprilysin
XM_011512856.1	XP_011511158.1	neprilysin isoform X1
NM_007287.3	NP_009218.2	neprilysin isoform a
NM_001354642.1	NP_001341571.1	neprilysin isoform a

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17309	NM_000902.4 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_001354643.1 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_007287.3 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1bis, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_001354642.1 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_007288.3 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_007289.4 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_006713646.3 Latest version!	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_006713647.4 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_011512855.2 Latest version!	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_011512856.2 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_011512858.1 Latest version!	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_011512857.2 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu103005	NM_001354644.1 Latest version!	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu17309	XM_006713647.2	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_011512855.1	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_007289.2	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_006713646.2	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_006713647.3	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_000902.3	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_011512857.1	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_007289.3	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_007288.2	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	XM_011512856.1	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17309	NM_007287.2	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1bis, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

MME ( NM_007289.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_009220.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_007289.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-06
Organism	Homo sapiens(Human)
Product	neprilysin
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA574242.1, X07166.1 and AC106724.3. On Oct 17, 2006 this sequence version replaced NM_007289.1. Transcript Variant: This variant (2b) is the longest transcript and includes alternate exon 2b. Variants 2b, 2a, 1bis and 1 all encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC101632.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009220.2
CDS	188..2440
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_007289.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007289.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_007288.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009219.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2a, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_007288.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117384.5 and AC106724.3. On Aug 17, 2017 this sequence version replaced NM_007288.2. Transcript Variant: This variant (2a) contains an alternate 5' UTR exon, compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.186886.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009219.2
CDS	296..2548
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_007288.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007288.3

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_000902.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000893.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_000902.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM151602.1, X07166.1 and AC106724.3. This sequence is a reference standard in the RefSeqGene project. On Oct 17, 2006 this sequence version replaced NM_000902.2. Transcript Variant: This variant (1) contains an alternate 5' UTR exon compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.199667.1, SRR1803613.116409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000893.2
CDS	121..2373
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_000902.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000902.3

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_007289.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_009220.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_007289.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117384.5 and AC106724.3. On Oct 1, 2019 this sequence version replaced NM_007289.3. Transcript Variant: This variant (2b) is the longest transcript and includes alternate exon 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC101632.1, DRR138524.75021.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009220.2
CDS	159..2411
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_007289.4
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007289.4

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_007287.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_009218.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1bis, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_007287.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB142029.1, X07166.1 and AC106724.3. On Oct 17, 2006 this sequence version replaced NM_007287.1. Transcript Variant: This variant (1bis) contains an alternate 5' UTR exon compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.89126.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009218.2
CDS	97..2349
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_007287.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1bis, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007287.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_000902.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000893.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_000902.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM151602.1, X07166.1 and AC106724.3. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_000902.3. Transcript Variant: This variant (1) contains an alternate 5' UTR exon compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.199667.1, SRR1803613.116409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000893.2
CDS	96..2348
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_000902.4
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000902.4

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_001354643.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341572.1 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_001354643.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117384.5, Y00811.1 and AC106724.3. On Aug 17, 2017 this sequence version replaced XM_006713646.3. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y00811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341572.1
CDS	235..2487
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_001354643.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354643.1

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_007289.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009220.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_007289.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117384.5 and AC106724.3. On Aug 17, 2017 this sequence version replaced NM_007289.2. Transcript Variant: This variant (2b) is the longest transcript and includes alternate exon 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC101632.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009220.2
CDS	467..2719
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_007289.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2b, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007289.3

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_007288.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_009219.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2a, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_007288.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-06
Organism	Homo sapiens(Human)
Product	neprilysin
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP418894.1, X07166.1 and AC106724.3. On Oct 17, 2006 this sequence version replaced NM_007288.1. Transcript Variant: This variant (2a) contains an alternate 5' UTR exon, compared to variant 2b. Variants 2b, 2a, 1bis and 1 all encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.186886.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009219.2
CDS	143..2395
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_007288.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 2a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007288.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_007287.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009218.2 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1bis, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_007287.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117384.5, DB142029.1, X07166.1 and AC106724.3. On Jun 2, 2019 this sequence version replaced NM_007287.2. Transcript Variant: This variant (1bis) contains an alternate 5' UTR exon compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.89126.1, DRR138518.421534.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009218.2
CDS	143..2395
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_007287.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 1bis, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007287.3

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_001354642.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341571.1 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	NM_001354642.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	neprilysin isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK291761.1 and AC106724.3. On Aug 17, 2017 this sequence version replaced XM_011512855.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 2b. Variants 1, 1bis, 2a, 2b, 3, and 4 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341571.1
CDS	212..2464
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	NM_001354642.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354642.1

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_011512858.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511160.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_011512858.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011511160.1

Translation

MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_011512858.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512858.1

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_011512855.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511157.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_011512855.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011511157.1

Translation

MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_011512855.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512855.1

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_006713647.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713710.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_006713647.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	neprilysin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006713647.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006713710.1
CDS	3281..5533
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_006713647.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713647.3

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_006713646.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713709.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_006713646.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006713709.1

Translation

MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_006713646.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713646.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_006713647.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713710.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_006713647.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_006713710.1

Translation

MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_006713647.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713647.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_011512855.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511157.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_011512855.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512855.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511157.1
CDS	212..2464
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_011512855.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512855.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_006713646.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713709.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_006713646.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006713646.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006713709.1
CDS	135..2387
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_006713646.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713646.3

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_011512856.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511158.1 Homo sapiens membrane metalloendopeptidase (MME), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_011512856.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	neprilysin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512856.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511158.1
CDS	139..2391
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_011512856.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512856.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_006713647.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713710.1 Homo sapiens membrane metalloendopeptidase (MME), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_006713647.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	neprilysin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006713647.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006713710.1
CDS	3282..5534
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_006713647.4
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713647.4

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_011512857.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511159.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_011512857.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011511159.1

Translation

MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_011512857.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512857.1

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_011512857.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511159.1 Homo sapiens membrane metalloendopeptidase (MME), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_011512857.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	neprilysin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512857.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511159.1
CDS	110..2362
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_011512857.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512857.2

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( XM_011512856.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511158.1 Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X2, mRNA.

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CloneID	OHu17309
Clone ID Related Accession (Same CDS sequence)	NM_007289.2 , XM_011512858.1 , XM_011512855.1 , NM_007288.3 , NM_000902.3 , XM_006713647.3 , XM_006713646.2 , XM_006713647.2 , XM_011512855.2 , NM_007289.4 , XM_006713646.3 , NM_007287.2 , XM_011512856.2 , XM_006713647.4 , NM_000902.4 , XM_011512857.1 , XM_011512857.2 , NM_001354643.1 , NM_007289.3 , NM_007288.2 , XM_011512856.1 , NM_007287.3 , NM_001354642.1
Accession Version	XM_011512856.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	neprilysin isoform X1
Comment

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011511158.1

Translation

MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW

Target ORF information:

RefSeq Version	XM_011512856.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens membrane metallo-endopeptidase (MME), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512856.1

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGCTGC TCGACTGATC CAAAACATGG ATGCCACCAC TGAGCCTTGT 
ACAGACTTTT TCAAATATGC TTGCGGAGGC TGGTTGAAAC GTAATGTCAT TCCCGAGACC 
AGCTCCCGTT ACGGCAACTT TGACATTTTA AGAGATGAAC TAGAAGTCGT TTTGAAAGAT 
GTCCTTCAAG AACCCAAAAC TGAAGATATA GTAGCAGTGC AGAAAGCAAA AGCATTGTAC 
AGGTCTTGTA TAAATGAATC TGCTATTGAT AGCAGAGGTG GAGAACCTCT ACTCAAACTG 
TTACCAGACA TATATGGGTG GCCAGTAGCA ACAGAAAACT GGGAGCAAAA ATATGGTGCT 
TCTTGGACAG CTGAAAAAGC TATTGCACAA CTGAATTCTA AATATGGGAA AAAAGTCCTT 
ATTAATTTGT TTGTTGGCAC TGATGATAAG AATTCTGTGA ATCATGTAAT TCATATTGAC 
CAACCTCGAC TTGGCCTCCC TTCTAGAGAT TACTATGAAT GCACTGGAAT CTATAAAGAG 
GCTTGTACAG CATATGTGGA TTTTATGATT TCTGTGGCCA GATTGATTCG TCAGGAAGAA 
AGATTGCCCA TCGATGAAAA CCAGCTTGCT TTGGAAATGA ATAAAGTTAT GGAATTGGAA 
AAAGAAATTG CCAATGCTAC GGCTAAACCT GAAGATCGAA ATGATCCAAT GCTTCTGTAT 
AACAAGATGA CATTGGCCCA GATCCAAAAT AACTTTTCAC TAGAGATCAA TGGGAAGCCA 
TTCAGCTGGT TGAATTTCAC AAATGAAATC ATGTCAACTG TGAATATTAG TATTACAAAT 
GAGGAAGATG TGGTTGTTTA TGCTCCAGAA TATTTAACCA AACTTAAGCC CATTCTTACC 
AAATATTCTG CCAGAGATCT TCAAAATTTA ATGTCCTGGA GATTCATAAT GGATCTTGTA 
AGCAGCCTCA GCCGAACCTA CAAGGAGTCC AGAAATGCTT TCCGCAAGGC CCTTTATGGT 
ACAACCTCAG AAACAGCAAC TTGGAGACGT TGTGCAAACT ATGTCAATGG GAATATGGAA 
AATGCTGTGG GGAGGCTTTA TGTGGAAGCA GCATTTGCTG GAGAGAGTAA ACATGTGGTC 
GAGGATTTGA TTGCACAGAT CCGAGAAGTT TTTATTCAGA CTTTAGATGA CCTCACTTGG 
ATGGATGCCG AGACAAAAAA GAGAGCTGAA GAAAAGGCCT TAGCAATTAA AGAAAGGATC 
GGCTATCCTG ATGACATTGT TTCAAATGAT AACAAACTGA ATAATGAGTA CCTCGAGTTG 
AACTACAAAG AAGATGAATA CTTCGAGAAC ATAATTCAAA ATTTGAAATT CAGCCAAAGT 
AAACAACTGA AGAAGCTCCG AGAAAAGGTG GACAAAGATG AGTGGATAAG TGGAGCAGCT 
GTAGTCAATG CATTTTACTC TTCAGGAAGA AATCAGATAG TCTTCCCAGC CGGCATTCTG 
CAGCCCCCCT TCTTTAGTGC CCAGCAGTCC AACTCATTGA ACTATGGGGG CATCGGCATG 
GTCATAGGAC ACGAAATCAC CCATGGCTTC GATGACAATG GCAGAAACTT TAACAAAGAT 
GGAGACCTCG TTGACTGGTG GACTCAACAG TCTGCAAGTA ACTTTAAGGA GCAATCCCAG 
TGCATGGTGT ATCAGTATGG AAACTTTTCC TGGGACCTGG CAGGTGGACA GCACCTTAAT 
GGAATTAATA CACTGGGAGA AAACATTGCT GATAATGGAG GTCTTGGTCA AGCATACAGA 
GCCTATCAGA ATTATATTAA AAAGAATGGC GAAGAAAAAT TACTTCCTGG ACTTGACCTA 
AATCACAAAC AACTATTTTT CTTGAACTTT GCACAGGTGT GGTGTGGAAC CTATAGGCCA 
GAGTATGCGG TTAACTCCAT TAAAACAGAT GTGCACAGTC CAGGCAATTT CAGGATTATT 
GGGACTTTGC AGAACTCTGC AGAGTTTTCA GAAGCCTTTC ACTGCCGCAA GAATTCATAC 
ATGAATCCAG AAAAGAAGTG CCGGGTTTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MME ( NM_001354644.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001341573.1 Homo sapiens membrane metalloendopeptidase (MME), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu103005
Clone ID Related Accession (Same CDS sequence)	NM_001354644.1
Accession Version	NM_001354644.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 243bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	neprilysin isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC117384.5 and BC106070.1. Transcript Variant: This variant (5) differs in the 3' UTR and coding sequence compared to variant 2b. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC106070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGGCAT GGTAGCACGC GCCTATAATC CCAGAGGGAG GAGAATTGCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001341573.1
CDS	467..709
Translation	MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSGMVARAYNPRGRRIA

Target ORF information:

RefSeq Version	NM_001354644.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane metalloendopeptidase (MME), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001354644.1

ORF Insert Sequence:

ATGGGCAAGT CAGAAAGTCA GATGGATATA ACTGATATCA ACACTCCAAA GCCAAAGAAG 
AAACAGCGAT GGACTCCACT GGAGATCAGC CTCTCGGTCC TTGTCCTGCT CCTCACCATC 
ATAGCTGTGA CAATGATCGC ACTCTATGCA ACCTACGATG ATGGTATTTG CAAGTCATCA 
GACTGCATAA AATCAGGCAT GGTAGCACGC GCCTATAATC CCAGAGGGAG GAGAATTGCT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	MME
Entrez Gene ID	4311
Full Name	membrane metalloendopeptidase
Synonyms	CALLA,CD10,CMT2T,NEP,SCA43,SFE
General protein information	Preferred Names membrane metalloendopeptidase Names neprilysin atriopeptidase common acute lymphocytic leukemia antigen membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) membrane metallo-endopeptidase variant 1 membrane metallo-endopeptidase variant 2 neprilysin-390 neprilysin-411 neutral endopeptidase 24.11 skin fibroblast elastase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q25.2
Summary	The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017].
Disorder MIM:	120520
Disorder Html:	Charcot-Marie-Tooth disease, axonal, type 2T, 617017 (3); ?Spinocerebellar ataxia 43, 617018 (3)

Bos taurus (cattle)	MME	NP_001179813.1
Homo sapiens (human)	MME	NP_009220.2
Pan troglodytes (chimpanzee)	MME	XP_001148532.1
Canis lupus familiaris (dog)	MME	XP_005634647.1
Gallus gallus (chicken)	MME	NP_001004412.1
	MME	XP_001105907.1
Mus musculus (house mouse)	Mme	NP_032630.2
Rattus norvegicus (Norway rat)	Mme	NP_036740.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

MME cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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