Gene Symbol | MIF |
Entrez Gene ID | 4282 |
Full Name | macrophage migration inhibitory factor |
Synonyms | GIF,GLIF,MMIF |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | {Rheumatoid arthritis, systemic juvenile, susceptibility to}, 604302 (3) |