Gene Symbol | MEF2C |
Entrez Gene ID | 4208 |
Full Name | myocyte enhancer factor 2C |
Synonyms | C5DELq14.3,DEL5q14.3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]. |
Disorder MIM: | |
Disorder Html: | Mental retardation, stereotypic movements, epilepsy, and/or cerebral malformations, 613443 (3); Chromosome 5q14.3 deletion syndrome, 613443 (4) |