Gene Symbol | MCL1 |
Entrez Gene ID | 4170 |
Full Name | MCL1, BCL2 family apoptosis regulator |
Synonyms | BCL2L3,EAT,MCL1-ES,MCL1L,MCL1S,Mcl-1,TM,bcl2-L-3,mcl1/EAT |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]. |
Disorder MIM: |