MAGEA6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAGEA6
Entrez Gene ID	4105
Full Name	MAGE family member A6
Synonyms	CT1.6,MAGE-3b,MAGE3B,MAGE6
General protein information	Preferred Names MAGE family member A6 Names melanoma-associated antigen 6 MAGE-6 antigen MAGE3B antigen cancer/testis antigen 1.6 cancer/testis antigen family 1, member 6 melanoma antigen family A, 6 melanoma antigen family A6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq28
Summary	This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
Disorder MIM:	300176

mRNA and Protein(s)

mRNA	Protein	Name
NM_005363.2	NP_005354.1	melanoma-associated antigen 6
XM_011531162.1	XP_011529464.1	melanoma-associated antigen 6 isoform X1
NM_175868.1	NP_787064.1	melanoma-associated antigen 6
NM_175868.2	NP_787064.1	melanoma-associated antigen 6
NM_005363.3	NP_005354.1	melanoma-associated antigen 6

Pathways from BioSystems

Homologies

	LOC711544	XP_001100355.2
Homo sapiens (human)	MAGEA6	NP_787064.1
Homo sapiens (human)	MAGEA3	NP_005353.1
	MAGEA3	XP_001094934.2

Gene Ontology
Bibliography

Related articles in PubMed

MAGEA6 promotes human glioma cell survival via targeting AMPK?1.
Pan SJ, Ren J, Jiang H, Liu W, Hu LY, Pan YX, Sun B, Sun QF, Bian LG
Cancer letters41221-29(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MAGEA6 promotes glioma cell survival possibly via targeting AMPKalpha1.
Title: MAGEA6 promotes human glioma cell survival via targeting AMPK?1.

MageA6 and MageA11 form a protein complex resulting in the stabilization of MageA11 and consequently the enhancement of androgen receptor activity.
Title: Functional interaction between co-expressed MAGE-A proteins.

MAGEA3/6 positivity was associated with significantly better disease-free survival.
Title: A Comprehensive Expression Analysis of Cancer Testis Antigens in Head and Neck Squamous Cell Carcinoma Revels MAGEA3/6 as a Marker for Recurrence.

Study describes a widespread mechanism to suppress AMPK through its ubiquitination and degradation by the cancer-specific MAGE-A3/6-TRIM28 ubiquitin ligase. MAGE-A3 and MAGE-A6 are highly similar proteins normally expressed only in the male germline but frequently re-activated in human cancers.
Title: Degradation of AMPK by a cancer-specific ubiquitin ligase.

To identify novel CTL epitopes from MAGE-A6 and MAGE-A12 antigens.
Title: Identification of novel MAGE-A6- and MAGE-A12-derived HLA-A24-restricted cytotoxic T lymphocyte epitopes using an in silico peptide-docking assay.

The following MAGEA6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEA6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07419	NM_005363.3 Latest version!	Homo sapiens MAGE family member A6 (MAGEA6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu07419	NM_175868.2 Latest version!	Homo sapiens MAGE family member A6 (MAGEA6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu07419	XM_011531162.1 Latest version!	Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu07419	NM_175868.1	Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu07419	NM_005363.2	Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAGEA6 ( NM_005363.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005354.1 Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07419
Clone ID Related Accession (Same CDS sequence)	NM_005363.2 , XM_011531162.1 , NM_175868.1 , NM_175868.2 , NM_005363.3
Accession Version	NM_005363.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	melanoma-associated antigen 6
Comment

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005354.1
Translation	MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAKLVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYIFATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFGDPKKLLTQYFVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE

Target ORF information:

RefSeq Version	NM_005363.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005363.2

ORF Insert Sequence:

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA6 ( NM_175868.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_787064.1 Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07419
Clone ID Related Accession (Same CDS sequence)	NM_005363.2 , XM_011531162.1 , NM_175868.1 , NM_175868.2 , NM_005363.3
Accession Version	NM_175868.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	melanoma-associated antigen 6
Comment

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_787064.1
Translation	MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAKLVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYIFATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFGDPKKLLTQYFVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE

Target ORF information:

RefSeq Version	NM_175868.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175868.1

ORF Insert Sequence:

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA6 ( NM_175868.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_787064.1 Homo sapiens MAGE family member A6 (MAGEA6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07419
Clone ID Related Accession (Same CDS sequence)	NM_005363.2 , XM_011531162.1 , NM_175868.1 , NM_175868.2 , NM_005363.3
Accession Version	NM_175868.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	melanoma-associated antigen 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM015284.1, BU182516.1, BC041599.1 and BX640600.1. On Dec 19, 2015 this sequence version replaced NM_175868.1. Transcript Variant: This variant (2) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU182516.1, BG179514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680, SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_787064.1
CDS	272..1216
Translation	MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAKLVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYIFATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFGDPKKLLTQYFVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE

Target ORF information:

RefSeq Version	NM_175868.2
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member A6 (MAGEA6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175868.2

ORF Insert Sequence:

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA6 ( NM_005363.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005354.1 Homo sapiens MAGE family member A6 (MAGEA6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu07419
Clone ID Related Accession (Same CDS sequence)	NM_005363.2 , XM_011531162.1 , NM_175868.1 , NM_175868.2 , NM_005363.3
Accession Version	NM_005363.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	melanoma-associated antigen 6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM015284.1, BC041599.1, BE542284.1 and BX640600.1. On Dec 19, 2015 this sequence version replaced NM_005363.2. Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM015284.1, BC041599.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005354.1
CDS	208..1152
Translation	MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAKLVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYIFATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFGDPKKLLTQYFVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE

Target ORF information:

RefSeq Version	NM_005363.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member A6 (MAGEA6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005363.3

ORF Insert Sequence:

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEA6 ( XM_011531162.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529464.1 Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant X1, mRNA.

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CloneID	OHu07419
Clone ID Related Accession (Same CDS sequence)	NM_005363.2 , XM_011531162.1 , NM_175868.1 , NM_175868.2 , NM_005363.3
Accession Version	XM_011531162.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	melanoma-associated antigen 6 isoform X1
Comment

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529464.1
Translation	MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAKLVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASDSLQLVFGIELMEVDPIGHVYIFATCLGLSYDGLLGDNQIMPKTGFLIIILAIIAKEGDCAPEEKIWEELSVLEVFEGREDSIFGDPKKLLTQYFVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHMVKISGGPRISYPLLHEWALREGEE

Target ORF information:

RefSeq Version	XM_011531162.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011531162.1

ORF Insert Sequence:

ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC 
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT 
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG 
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC 
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG 
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC 
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG 
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC 
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC 
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA 
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG 
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG 
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA 
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC 
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MAGEA6 promotes human glioma cell survival via targeting AMPK?1.
Cancer letters41221-29(2018 Jan)
Pan SJ,Ren J,Jiang H,Liu W,Hu LY,Pan YX,Sun B,Sun QF,Bian LG

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MAGEA6 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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