MAG cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAG
Entrez Gene ID	4099
Full Name	myelin associated glycoprotein
Synonyms	GMA,S-MAG,SIGLEC-4A,SIGLEC4A,SPG75
General protein information	Preferred Names myelin associated glycoprotein Names myelin-associated glycoprotein sialic acid binding Ig-like lectin 4A sialic acid-binding immunoglobulin-like lectin 4A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.12
Summary	The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010].
Disorder MIM:	159460
Disorder Html:	Spastic paraplegia 75, autosomal recessive, 616680 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002361.4	NP_002352.1	myelin-associated glycoprotein isoform a precursor
NM_001199216.1	NP_001186145.1	myelin-associated glycoprotein isoform c
NM_002361.3	NP_002352.1	myelin-associated glycoprotein isoform a precursor
NM_080600.2	NP_542167.1	myelin-associated glycoprotein isoform b precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Mag	NP_058886.1
Xenopus tropicalis (tropical clawed frog)	mag	XP_002943135.1
Bos taurus (cattle)	MAG	NP_001035660.2
Danio rerio (zebrafish)	mag	NP_001007063.1
Homo sapiens (human)	MAG	NP_002352.1
	MAG	XP_001111459.2
Mus musculus (house mouse)	Mag	NP_034888.1
Canis lupus familiaris (dog)	MAG	XP_005616772.1

Gene Ontology
Bibliography

Related articles in PubMed

Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder.
Lossos A, Elazar N, Lerer I, Schueler-Furman O, Fellig Y, Glick B, Zimmerman BE, Azulay H, Dotan S, Goldberg S, Gomori JM, Ponger P, Newman JP, Marreed H, Steck AJ, Schaeren-Wiemers N, Mor N, Harel M, Geiger T, Eshed-Eisenbach Y, Meiner V, Peles E
Brain : a journal of neurology138(Pt 9)2521-36(2015 Sep)

Heterogeneity of Polyneuropathy Associated with Anti-MAG Antibodies.
Magy L, Kabor? R, Mathis S, Lebeau P, Ghorab K, Caudie C, Vallat JM
Journal of immunology research2015450391(2015)

LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.
Mantuano E, Lam MS, Gonias SL
The Journal of biological chemistry288(47)34009-18(2013 Nov)

The possible relationship between allergic manifestations and elevated serum levels of brain specific auto-antibodies in autistic children.
Mostafa GA, Al-Ayadhi LY
Journal of neuroimmunology261(1-2)77-81(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study identify involvement of myelin-associated glycoprotein in this family with a disorder affecting the central and peripheral nervous system, and suggest that loss of the protein function is responsible for the unique clinical phenotype
Title: Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder.

polyneuropathy associated with anti-MAG antibodies is less homogeneous.
Title: Heterogeneity of Polyneuropathy Associated with Anti-MAG Antibodies.

LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.
Title: LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.

Increased serum levels of MAG (and MBP) were found in autistic patients with allergic manifestations compared to those without these manifestations.
Title: The possible relationship between allergic manifestations and elevated serum levels of brain specific auto-antibodies in autistic children.

Results show that MAG is important for axon-glia contact in a model for Charcot-Marie-Tooth disease type 1A, and suggest that its increased expression in patients has a compensatory role in the disease pathology
Title: An essential role of MAG in mediating axon-myelin attachment in Charcot-Marie-Tooth 1A disease.

The following MAG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13781	NM_001199216.1 Latest version!	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu13785	NM_002361.4 Latest version!	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$204.50-$286.30 $409.00
OHu19652	NM_080600.2 Latest version!	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
View Old Accession Versions >>
OHu13785	NM_002361.3	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$204.50-$286.30 $409.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAG ( NM_001199216.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186145.1 Homo sapiens myelin associated glycoprotein (MAG), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu13781
Clone ID Related Accession (Same CDS sequence)	NM_001199216.1
Accession Version	NM_001199216.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1806bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	myelin-associated glycoprotein isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC331168.1, AK308976.1 and BC093045.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294644.1, SRR1660807.146617.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCCTCGT CCATCTCGGC CTTCGAAGGC ACGTGCGTCT CCATCCCCTG CCGCTTTGAC 
TTCCCGGATG AGCTGCGGCC CGCTGTGGTG CATGGTGTCT GGTACTTCAA TAGCCCCTAC 
CCCAAGAACT ACCCCCCGGT GGTCTTCAAG TCGCGCACCC AAGTAGTCCA CGAGAGCTTC 
CAGGGCCGCA GCCGCCTCCT GGGGGACCTG GGCCTGCGAA ACTGCACCCT CCTGCTCAGC 
AACGTCAGCC CCGAGCTGGG CGGGAAGTAC TACTTCCGTG GGGACCTGGG CGGCTACAAC 
CAGTACACCT TCTCAGAGCA CAGCGTCCTG GATATCGTCA ACACCCCCAA CATCGTGGTG 
CCCCCAGAGG TGGTGGCAGG CACGGAGGTG GAGGTCAGCT GCATGGTGCC GGACAACTGC 
CCAGAGCTGC GCCCTGAGCT GAGCTGGCTG GGCCACGAGG GGCTGGGGGA GCCCGCTGTG 
CTGGGCCGGC TGCGGGAGGA CGAGGGCACC TGGGTGCAGG TGTCACTGCT GCACTTCGTG 
CCCACGAGGG AGGCCAACGG CCACAGGCTG GGCTGCCAGG CCTCCTTCCC CAACACCACC 
CTGCAGTTCG AGGGCTACGC CAGCATGGAC GTCAAGTACC CCCCGGTGAT TGTGGAGATG 
AACTCCTCGG TGGAGGCCAT CGAGGGCTCC CACGTGAGCC TGCTCTGTGG GGCTGACAGC 
AACCCCCCGC CGCTGCTGAC CTGGATGCGG GACGGGACAG TCCTCCGGGA GGCGGTGGCC 
GAGAGCCTGC TCCTGGAGCT GGAGGAGGTG ACCCCCGCCG AAGACGGCGT CTATGCCTGC 
CTGGCCGAGA ATGCCTATGG CCAGGACAAC CGCACCGTGG GGCTCAGTGT CATGTATGCA 
CCCTGGAAGC CAACAGTGAA CGGGACAATG GTGGCCGTAG AGGGGGAGAC GGTCTCTATC 
TTGTGCTCCA CACAGAGCAA CCCGGACCCT ATTCTCACCA TCTTCAAGGA GAAGCAGATC 
CTGTCCACGG TCATCTACGA GAGCGAGCTG CAGCTGGAGC TGCCGGCCGT GTCACCCGAG 
GATGATGGAG AGTACTGGTG TGTGGCTGAG AACCAGTATG GCCAGAGGGC CACCGCCTTC 
AACCTGTCTG TGGAGTTCGC CCCTGTGCTC CTCCTGGAGT CCCACTGCGC GGCAGCCCGA 
GACACGGTGC AGTGCCTGTG CGTGGTGAAG TCCAACCCGG AGCCGTCCGT GGCCTTTGAG 
CTGCCATCGC GCAATGTGAC CGTGAACGAG AGCGAGCGGG AGTTCGTGTA CTCGGAGCGC 
AGCGGCCTCG TGCTCACCAG CATCCTCACG CTGCGGGGGC AGGCCCAGGC CCCGCCCCGC 
GTCATCTGCA CCGCGAGGAA CCTCTATGGC GCCAAGAGCC TGGAGCTGCC CTTCCAGGGA 
GCCCATCGAC TGATGTGGGC CAAGATCGGG CCTGTGGGCG CCGTGGTCGC CTTTGCCATC 
CTGATTGCCA TCGTCTGCTA CATTACCCAG ACACGCAGGA AAAAGAACGT GACAGAGAGC 
CCCAGCTTCT CGGCAGGGGA CAACCCTCCC GTCCTGTTCA GCAGCGACTT CCGCATCTCT 
GGGGCACCAG AGAAGTACGA GAGCGAGAGG CGCCTGGGAT CTGAGAGGAG GCTGCTGGGC 
CTTCGGGGTG AGCCCCCAGA GCTGGACCTG AGCTATTCTC ACTCGGACCT GGGGAAACGG 
CCCACCAAGG ACAGCTACAC GCTGACGGAG GAGCTAGCTG AGTATGCTGA AATCCGGGTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186145.1
CDS	261..2066
Translation	MPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK

Target ORF information:

RefSeq Version	NM_001199216.1
Organism	Homo sapiens(human)
Definition	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199216.1

ORF Insert Sequence:

ATGCCCTCGT CCATCTCGGC CTTCGAAGGC ACGTGCGTCT CCATCCCCTG CCGCTTTGAC 
TTCCCGGATG AGCTGCGGCC CGCTGTGGTG CATGGTGTCT GGTACTTCAA TAGCCCCTAC 
CCCAAGAACT ACCCCCCGGT GGTCTTCAAG TCGCGCACCC AAGTAGTCCA CGAGAGCTTC 
CAGGGCCGCA GCCGCCTCCT GGGGGACCTG GGCCTGCGAA ACTGCACCCT CCTGCTCAGC 
AACGTCAGCC CCGAGCTGGG CGGGAAGTAC TACTTCCGTG GGGACCTGGG CGGCTACAAC 
CAGTACACCT TCTCAGAGCA CAGCGTCCTG GATATCGTCA ACACCCCCAA CATCGTGGTG 
CCCCCAGAGG TGGTGGCAGG CACGGAGGTG GAGGTCAGCT GCATGGTGCC GGACAACTGC 
CCAGAGCTGC GCCCTGAGCT GAGCTGGCTG GGCCACGAGG GGCTGGGGGA GCCCGCTGTG 
CTGGGCCGGC TGCGGGAGGA CGAGGGCACC TGGGTGCAGG TGTCACTGCT GCACTTCGTG 
CCCACGAGGG AGGCCAACGG CCACAGGCTG GGCTGCCAGG CCTCCTTCCC CAACACCACC 
CTGCAGTTCG AGGGCTACGC CAGCATGGAC GTCAAGTACC CCCCGGTGAT TGTGGAGATG 
AACTCCTCGG TGGAGGCCAT CGAGGGCTCC CACGTGAGCC TGCTCTGTGG GGCTGACAGC 
AACCCCCCGC CGCTGCTGAC CTGGATGCGG GACGGGACAG TCCTCCGGGA GGCGGTGGCC 
GAGAGCCTGC TCCTGGAGCT GGAGGAGGTG ACCCCCGCCG AAGACGGCGT CTATGCCTGC 
CTGGCCGAGA ATGCCTATGG CCAGGACAAC CGCACCGTGG GGCTCAGTGT CATGTATGCA 
CCCTGGAAGC CAACAGTGAA CGGGACAATG GTGGCCGTAG AGGGGGAGAC GGTCTCTATC 
TTGTGCTCCA CACAGAGCAA CCCGGACCCT ATTCTCACCA TCTTCAAGGA GAAGCAGATC 
CTGTCCACGG TCATCTACGA GAGCGAGCTG CAGCTGGAGC TGCCGGCCGT GTCACCCGAG 
GATGATGGAG AGTACTGGTG TGTGGCTGAG AACCAGTATG GCCAGAGGGC CACCGCCTTC 
AACCTGTCTG TGGAGTTCGC CCCTGTGCTC CTCCTGGAGT CCCACTGCGC GGCAGCCCGA 
GACACGGTGC AGTGCCTGTG CGTGGTGAAG TCCAACCCGG AGCCGTCCGT GGCCTTTGAG 
CTGCCATCGC GCAATGTGAC CGTGAACGAG AGCGAGCGGG AGTTCGTGTA CTCGGAGCGC 
AGCGGCCTCG TGCTCACCAG CATCCTCACG CTGCGGGGGC AGGCCCAGGC CCCGCCCCGC 
GTCATCTGCA CCGCGAGGAA CCTCTATGGC GCCAAGAGCC TGGAGCTGCC CTTCCAGGGA 
GCCCATCGAC TGATGTGGGC CAAGATCGGG CCTGTGGGCG CCGTGGTCGC CTTTGCCATC 
CTGATTGCCA TCGTCTGCTA CATTACCCAG ACACGCAGGA AAAAGAACGT GACAGAGAGC 
CCCAGCTTCT CGGCAGGGGA CAACCCTCCC GTCCTGTTCA GCAGCGACTT CCGCATCTCT 
GGGGCACCAG AGAAGTACGA GAGCGAGAGG CGCCTGGGAT CTGAGAGGAG GCTGCTGGGC 
CTTCGGGGTG AGCCCCCAGA GCTGGACCTG AGCTATTCTC ACTCGGACCT GGGGAAACGG 
CCCACCAAGG ACAGCTACAC GCTGACGGAG GAGCTAGCTG AGTATGCTGA AATCCGGGTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAG ( NM_002361.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002352.1 Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13785
Clone ID Related Accession (Same CDS sequence)	NM_002361.4 , NM_002361.3
Accession Version	NM_002361.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	myelin-associated glycoprotein isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK223562.1 and BC093045.1. On Nov 22, 2018 this sequence version replaced NM_002361.3. Transcript Variant: This variant (1) lacks exon 11 and has the stop codon in exon 12, as compared to variant 2. Isoform a is 44 aa longer and contains a different carboxy terminus when compared to isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK222649.1, AK223562.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000392213.8/ ENSP00000376048.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC 
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC 
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA 
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC 
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC 
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC 
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG 
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG 
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA 
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC 
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG 
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC 
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC 
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC 
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC 
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG 
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC 
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG 
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG 
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC 
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG 
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC 
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC 
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG 
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG 
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG 
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC 
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGAGCG AGAGGCGCCT GGGATCTGAG 
AGGAGGCTGC TGGGCCTTCG GGGTGAGCCC CCAGAGCTGG ACCTGAGCTA TTCTCACTCG 
GACCTGGGGA AACGGCCCAC CAAGGACAGC TACACGCTGA CGGAGGAGCT AGCTGAGTAT 
GCTGAAATCC GGGTCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002352.1
CDS	124..2004
Translation	MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK

Target ORF information:

RefSeq Version	NM_002361.4
Organism	Homo sapiens(human)
Definition	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002361.4

ORF Insert Sequence:

ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC 
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC 
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA 
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC 
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC 
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC 
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG 
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG 
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA 
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC 
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG 
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC 
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC 
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC 
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC 
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG 
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC 
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG 
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG 
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC 
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG 
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC 
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC 
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG 
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG 
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG 
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC 
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGAGCG AGAGGCGCCT GGGATCTGAG 
AGGAGGCTGC TGGGCCTTCG GGGTGAGCCC CCAGAGCTGG ACCTGAGCTA TTCTCACTCG 
GACCTGGGGA AACGGCCCAC CAAGGACAGC TACACGCTGA CGGAGGAGCT AGCTGAGTAT 
GCTGAAATCC GGGTCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAG ( NM_002361.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002352.1 Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13785
Clone ID Related Accession (Same CDS sequence)	NM_002361.4 , NM_002361.3
Accession Version	NM_002361.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1881bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	myelin-associated glycoprotein isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC331168.1, AK223562.1 and BC093045.1. On or before Aug 31, 2013 this sequence version replaced XM_005258946.1, NM_002361.2. Transcript Variant: This variant (1) lacks exon 11 and has the stop codon in exon 12, as compared to variant 2. Isoform a is 44 aa longer and contains a different carboxy terminus when compared to isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223562.1, SRR1803611.195372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC 
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC 
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA 
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC 
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC 
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC 
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG 
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG 
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA 
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC 
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG 
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC 
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC 
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC 
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC 
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG 
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC 
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG 
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG 
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC 
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG 
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC 
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC 
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG 
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG 
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG 
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC 
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGAGCG AGAGGCGCCT GGGATCTGAG 
AGGAGGCTGC TGGGCCTTCG GGGTGAGCCC CCAGAGCTGG ACCTGAGCTA TTCTCACTCG 
GACCTGGGGA AACGGCCCAC CAAGGACAGC TACACGCTGA CGGAGGAGCT AGCTGAGTAT 
GCTGAAATCC GGGTCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002352.1
CDS	199..2079
Translation	MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK

Target ORF information:

RefSeq Version	NM_002361.3
Organism	Homo sapiens(human)
Definition	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002361.3

ORF Insert Sequence:

ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC 
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC 
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA 
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC 
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC 
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC 
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG 
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG 
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA 
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC 
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG 
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC 
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC 
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC 
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC 
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG 
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC 
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG 
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG 
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC 
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG 
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC 
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC 
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG 
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG 
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG 
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC 
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGAGCG AGAGGCGCCT GGGATCTGAG 
AGGAGGCTGC TGGGCCTTCG GGGTGAGCCC CCAGAGCTGG ACCTGAGCTA TTCTCACTCG 
GACCTGGGGA AACGGCCCAC CAAGGACAGC TACACGCTGA CGGAGGAGCT AGCTGAGTAT 
GCTGAAATCC GGGTCAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAG ( NM_080600.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_542167.1 Homo sapiens myelin associated glycoprotein (MAG), transcript variant 2, mRNA.

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CloneID	OHu19652
Clone ID Related Accession (Same CDS sequence)	NM_080600.2
Accession Version	NM_080600.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	myelin-associated glycoprotein isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC331168.1 and BC093045.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced XM_005258947.1, NM_080600.1. Transcript Variant: This variant (2) is a full-length transcript with the stop codon contained in exon 11. It encodes an isoform (b) that is 44 aa shorter and contains a different carboxy terminus when compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC093045.1, SRR1660807.260944.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC 
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC 
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA 
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC 
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC 
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC 
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG 
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG 
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA 
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC 
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG 
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC 
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC 
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC 
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC 
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG 
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC 
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG 
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG 
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC 
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG 
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC 
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC 
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG 
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG 
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG 
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC 
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGTCCA AAGAGGTTTC TACCCTGGAA 
TCTCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542167.1
CDS	199..1947
Translation	MIFLTALPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPPVLFSSDFRISGAPEKYESKEVSTLESH

Target ORF information:

RefSeq Version	NM_080600.2
Organism	Homo sapiens(human)
Definition	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080600.2

ORF Insert Sequence:

ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC 
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC 
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA 
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC 
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC 
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC 
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG 
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG 
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA 
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC 
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG 
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC 
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC 
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC 
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC 
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG 
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC 
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG 
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG 
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC 
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG 
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC 
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC 
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG 
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG 
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG 
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC 
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGTCCA AAGAGGTTTC TACCCTGGAA 
TCTCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder.
Brain : a journal of neurology138(Pt 9)2521-36(2015 Sep)
Lossos A,Elazar N,Lerer I,Schueler-Furman O,Fellig Y,Glick B,Zimmerman BE,Azulay H,Dotan S,Goldberg S,Gomori JM,Ponger P,Newman JP,Marreed H,Steck AJ,Schaeren-Wiemers N,Mor N,Harel M,Geiger T,Eshed-Eisenbach Y,Meiner V,Peles E

Heterogeneity of Polyneuropathy Associated with Anti-MAG Antibodies.
Journal of immunology research2015450391(2015)
Magy L,Kabor? R,Mathis S,Lebeau P,Ghorab K,Caudie C,Vallat JM

LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.
The Journal of biological chemistry288(47)34009-18(2013 Nov)
Mantuano E,Lam MS,Gonias SL

The possible relationship between allergic manifestations and elevated serum levels of brain specific auto-antibodies in autistic children.
Journal of neuroimmunology261(1-2)77-81(2013 Aug)
Mostafa GA,Al-Ayadhi LY

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MAG cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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